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4GZZ
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Crystal structures of bacterial RNA Polymerase paused elongation complexes
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Weixlbaumer, A, Leon, K, Landick, R, Darst, S.A.
登録日2012-09-06
公開日2013-02-13
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (4.2927 Å)
主引用文献Structural basis of transcriptional pausing in bacteria.
Cell(Cambridge,Mass.), 152, 2013
6WS0
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BU of 6ws0 by Molmil
Rational drug design of phenazopyridine derivatives as novel inhibitors of Rev1-CT
分子名称: DNA polymerase zeta catalytic subunit, DNA repair protein REV1, Mitotic spindle assembly checkpoint protein MAD2B
著者McPherson, K.S, Korzhnev, D.M.
登録日2020-04-30
公開日2020-12-23
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Structure-Based Drug Design of Phenazopyridine Derivatives as Inhibitors of Rev1 Interactions in Translesion Synthesis.
Chemmedchem, 16, 2021
6BI7
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BU of 6bi7 by Molmil
Crystal structure of Rev7-WT/Rev3 as a monomer under high-salt conditions
分子名称: DNA polymerase zeta catalytic subunit, Mitotic spindle assembly checkpoint protein MAD2B
著者Rizzo, A.A, Korzhnev, D.M, Hao, B, Li, Y.
登録日2017-11-01
公開日2018-08-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Rev7 dimerization is important for assembly and function of the Rev1/Pol zeta translesion synthesis complex.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6U2U
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BU of 6u2u by Molmil
Helix-Loop-helix motif of mouse DNA-binding protein inhibitor ID-1
分子名称: DNA-binding protein inhibitor ID-1
著者Benezra, R, Pavletich, N.P, Goldgur, Y, Gall, A.-L.
登録日2019-08-20
公開日2019-10-16
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献A Small-Molecule Pan-Id Antagonist Inhibits Pathologic Ocular Neovascularization.
Cell Rep, 29, 2019
6MKO
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BU of 6mko by Molmil
Crystallographic solvent mapping analysis of glycerol bound to APE1
分子名称: DNA-(apurinic or apyrimidinic site) lyase, GLYCEROL
著者Georgiadis, M.M, He, H, Chen, Q.
登録日2018-09-25
公開日2019-01-30
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Discovery of Macrocyclic Inhibitors of Apurinic/Apyrimidinic Endonuclease 1.
J. Med. Chem., 62, 2019
7SVV
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BU of 7svv by Molmil
TnsBctd-TnsC complex
分子名称: DNA (5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), MAGNESIUM ION, ...
著者Park, J, Tsai, A.W.T, Kellogg, E.H.
登録日2021-11-19
公開日2022-08-10
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.54 Å)
主引用文献Mechanistic details of CRISPR-associated transposon recruitment and integration revealed by cryo-EM.
Proc.Natl.Acad.Sci.USA, 119, 2022
8GUJ
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Bre1-nucleosome complex (Model II)
分子名称: DNA (147-mer), E3 ubiquitin-protein ligase BRE1A, E3 ubiquitin-protein ligase BRE1B, ...
著者Onishi, S, Sato, K, Hamada, K, Nishizawa, T, Nureki, O, Ogata, K, Sengoku, T.
登録日2022-09-12
公開日2023-09-20
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structure of the human Bre1 complex bound to the nucleosome.
Nat Commun, 15, 2024
8GUI
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BU of 8gui by Molmil
Bre1-nucleosome complex (Model I)
分子名称: DNA (147-mer), E3 ubiquitin-protein ligase BRE1A, E3 ubiquitin-protein ligase BRE1B, ...
著者Onishi, S, Hamada, K, Sato, K, Nishizawa, T, Nureki, O, Ogata, K, Sengoku, T.
登録日2022-09-12
公開日2023-09-20
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (2.81 Å)
主引用文献Structure of the human Bre1 complex bound to the nucleosome.
Nat Commun, 15, 2024
3OS1
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BU of 3os1 by Molmil
PFV target capture complex (TCC) at 2.97 A resolution
分子名称: DNA (5'-D(*AP*TP*TP*GP*TP*CP*AP*TP*GP*GP*AP*AP*TP*TP*TP*CP*GP*CP*A)-3'), DNA (5'-D(*CP*CP*CP*GP*AP*GP*GP*CP*AP*CP*GP*TP*GP*CP*TP*AP*GP*CP*AP*CP*GP*TP*GP*CP*CP*TP*CP*GP*GP*G)-3'), DNA (5'-D(*TP*GP*CP*GP*AP*AP*AP*TP*TP*CP*CP*AP*TP*GP*AP*CP*(2DA))-3'), ...
著者Maertens, G.N, Hare, S, Cherepanov, P.
登録日2010-09-08
公開日2010-11-17
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.97 Å)
主引用文献The mechanism of retroviral integration from X-ray structures of its key intermediates
Nature, 468, 2010
3OS0
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BU of 3os0 by Molmil
PFV strand transfer complex (STC) at 2.81 A resolution
分子名称: DNA (5'-D(*AP*TP*TP*GP*TP*CP*AP*TP*GP*GP*AP*AP*TP*TP*TP*CP*GP*CP*A)-3'), DNA (5'-D(*CP*CP*CP*GP*AP*G*GP*CP*AP*CP*GP*TP*G)-3'), DNA (5'-D(*TP*GP*CP*GP*AP*AP*AP*TP*TP*CP*CP*AP*TP*GP*AP*CP*A)-3'), ...
著者Maertens, G.N, Hare, S, Cherepanov, P.
登録日2010-09-08
公開日2010-11-17
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献The mechanism of retroviral integration from X-ray structures of its key intermediates
Nature, 468, 2010
1HQM
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BU of 1hqm by Molmil
CRYSTAL STRUCTURE OF THERMUS AQUATICUS CORE RNA POLYMERASE-INCLUDES COMPLETE STRUCTURE WITH SIDE-CHAINS (EXCEPT FOR DISORDERED REGIONS)-FURTHER REFINED FROM ORIGINAL DEPOSITION-CONTAINS ADDITIONAL SEQUENCE INFORMATION
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Minakhin, L, Bhagat, S, Brunning, A, Campbell, E.A, Darst, S.A, Ebright, R.H, Severinov, K.
登録日2000-12-18
公開日2001-02-07
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Bacterial RNA polymerase subunit omega and eukaryotic RNA polymerase subunit RPB6 are sequence, structural, and functional homologs and promote RNA polymerase assembly.
Proc.Natl.Acad.Sci.USA, 98, 2001
3TAF
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BU of 3taf by Molmil
5-fluorocytosine paired with ddGMP in RB69 gp43
分子名称: DNA (5'-D(*CP*CP*(C37)P*GP*GP*TP*AP*TP*GP*AP*CP*AP*GP*CP*CP*GP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*GP*CP*TP*GP*TP*CP*AP*TP*AP*CP*CP*G)-3'), DNA-directed DNA polymerase, ...
著者Zahn, K.E.
登録日2011-08-04
公開日2011-11-09
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The miscoding potential of 5-hydroxycytosine arises due to template instability in the replicative polymerase active site.
Biochemistry, 50, 2011
1D3U
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TATA-BINDING PROTEIN/TRANSCRIPTION FACTOR (II)B/BRE+TATA-BOX COMPLEX FROM PYROCOCCUS WOESEI
分子名称: DNA 23-MER: BRE+TATA-BOX, DNA 24-MER: BRE+TATA-BOX, TATA-BINDING PROTEIN, ...
著者Littlefield, O, Korkhin, Y, Sigler, P.B.
登録日1999-10-01
公開日1999-11-15
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The structural basis for the oriented assembly of a TBP/TFB/promoter complex.
Proc.Natl.Acad.Sci.USA, 96, 1999
3OS2
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BU of 3os2 by Molmil
PFV target capture complex (TCC) at 3.32 A resolution
分子名称: DNA (5'-D(*AP*TP*TP*GP*TP*CP*AP*TP*GP*GP*AP*AP*TP*TP*TP*CP*GP*CP*A)-3'), DNA (5'-D(*CP*CP*CP*GP*AP*GP*GP*CP*AP*CP*GP*TP*GP*CP*TP*AP*GP*CP*AP*CP*GP*TP*GP*CP*CP*TP*CP*GP*GP*G)-3'), DNA (5'-D(*TP*GP*CP*GP*AP*AP*AP*TP*TP*CP*CP*AP*TP*GP*AP*CP*A)-3'), ...
著者Maertens, G.N, Hare, S, Cherepanov, P.
登録日2010-09-08
公開日2010-11-17
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.32 Å)
主引用文献The mechanism of retroviral integration from X-ray structures of its key intermediates
Nature, 468, 2010
3TAG
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BU of 3tag by Molmil
5-fluorocytosine paired with dAMP in RB69 gp43
分子名称: DNA (5'-D(*CP*CP*(C37)P*GP*GP*TP*AP*TP*GP*AP*CP*AP*GP*CP*CP*GP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*GP*CP*TP*GP*TP*CP*AP*TP*AP*CP*CP*A)-3'), DNA-directed DNA polymerase, ...
著者Zahn, K.E.
登録日2011-08-04
公開日2011-11-09
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献The miscoding potential of 5-hydroxycytosine arises due to template instability in the replicative polymerase active site.
Biochemistry, 50, 2011
1AIS
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BU of 1ais by Molmil
TATA-BINDING PROTEIN/TRANSCRIPTION FACTOR (II)B/TATA-BOX COMPLEX FROM PYROCOCCUS WOESEI
分子名称: DNA (5'-D(*AP*AP*CP*TP*TP*AP*CP*TP*TP*TP*(5IU)P*(5IU)P*AP*AP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*TP*TP*AP*AP*AP*AP*AP*GP*TP*AP*AP*GP*TP*T )-3'), PROTEIN (TATA-BINDING PROTEIN), ...
著者Kosa, P.F, Ghosh, G, Dedecker, B.S, Sigler, P.B.
登録日1997-04-24
公開日1997-07-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The 2.1-A crystal structure of an archaeal preinitiation complex: TATA-box-binding protein/transcription factor (II)B core/TATA-box.
Proc.Natl.Acad.Sci.USA, 94, 1997
1H2I
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BU of 1h2i by Molmil
Human Rad52 protein, N-terminal domain
分子名称: DNA REPAIR PROTEIN RAD52 HOMOLOG
著者Singleton, M.R, Wentzell, L.M, Liu, Y, West, S.C, Wigley, D.B.
登録日2002-08-09
公開日2002-10-10
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of the Single-Strand Annealing Domain of Human Rad52 Protein
Proc.Natl.Acad.Sci.USA, 99, 2002
5GSE
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BU of 5gse by Molmil
Crystal structure of unusual nucleosome
分子名称: DNA (250-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
著者Kato, D, Osakabe, A, Arimura, Y, Park, S.Y, Kurumizaka, H.
登録日2016-08-16
公開日2017-05-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.14 Å)
主引用文献Crystal structure of the overlapping dinucleosome composed of hexasome and octasome
Science, 356, 2017
5OF3
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BU of 5of3 by Molmil
Crystal structure of the heterotrimeric PriSLX primase from S. solfataricus.
分子名称: DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA primase large subunit PriL, DNA primase small subunit PriS, ...
著者Pellegrini, L, Holzer, S.
登録日2017-07-10
公開日2017-11-29
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.906 Å)
主引用文献Primer synthesis by a eukaryotic-like archaeal primase is independent of its Fe-S cluster.
Nat Commun, 8, 2017
7X3X
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BU of 7x3x by Molmil
Cryo-EM structure of N1 nucleosome-RA
分子名称: DNA (146-MER), Histone H2A, Histone H2B 1.1, ...
著者Lifei, L, Kangjing, C, Chen, Z.
登録日2022-03-01
公開日2023-09-20
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structure of the ISW1a complex bound to the dinucleosome.
Nat.Struct.Mol.Biol., 31, 2024
3PWE
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BU of 3pwe by Molmil
Crystal structure of the E. coli beta clamp mutant R103C, I305C, C260S, C333S at 2.2A resolution
分子名称: DNA polymerase III subunit beta
著者Marzahn, M.R, Robbins, A.H, McKenna, R, Bloom, L.B.
登録日2010-12-08
公開日2011-10-19
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.199 Å)
主引用文献The E. coli clamp loader can actively pry open the beta-sliding clamp
J.Biol.Chem., 286, 2011
6C31
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BU of 6c31 by Molmil
Crystal structure of TetR family protein Rv0078 in complex with DNA
分子名称: DNA (5'-D(*GP*TP*TP*AP*CP*CP*GP*GP*CP*AP*GP*TP*CP*TP*GP*CP*TP*TP*GP*TP*AP*AP*A)-3'), DNA (5'-D(P*AP*CP*AP*AP*GP*CP*AP*GP*AP*CP*TP*GP*CP*CP*GP*GP*TP*AP*AP*C)-3'), TetR family transcriptional regulator
著者Hsu, H.C, Li, H.
登録日2018-01-09
公開日2018-07-04
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Cytokinin Signaling in Mycobacterium tuberculosis.
MBio, 9, 2018
8G57
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Structure of nucleosome-bound Sirtuin 6 deacetylase
分子名称: DNA strand 1, DNA strand 2, Histone H2A type 1-B/E, ...
著者Chio, U.S, Rechiche, O, Bryll, A.R, Zhu, J, Feldman, J.L, Peterson, C.L, Tan, S, Armache, J.-P.
登録日2023-02-11
公開日2023-04-26
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.07 Å)
主引用文献Cryo-EM structure of the human Sirtuin 6-nucleosome complex.
Sci Adv, 9, 2023
1QPI
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CRYSTAL STRUCTURE OF TETRACYCLINE REPRESSOR/OPERATOR COMPLEX
分子名称: DNA (5'-D(*CP*CP*TP*AP*TP*CP*AP*AP*TP*GP*AP*TP*AP*GP*A)-3'), DNA (5'-D(*TP*CP*TP*AP*TP*CP*AP*TP*TP*GP*AP*TP*AP*GP*G)-3'), IMIDAZOLE, ...
著者Orth, P, Schnappinger, D, Hillen, W, Saenger, W, Hinrichs, W.
登録日1999-05-25
公開日2000-02-28
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis of gene regulation by the tetracycline inducible Tet repressor-operator system.
Nat.Struct.Biol., 7, 2000
3LPE
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BU of 3lpe by Molmil
Crystal structure of Spt4/5NGN heterodimer complex from Methanococcus jannaschii
分子名称: DNA-directed RNA polymerase subunit E'', Putative transcription antitermination protein nusG, ZINC ION
著者Hirtreiter, A, Damsma, G.E, Cheung, A.C.M, Klose, D, Grohmann, D, Vojnic, E, Martin, A.C.R, Cramer, P, Werner, F.
登録日2010-02-05
公開日2010-03-09
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Spt4/5 stimulates transcription elongation through the RNA polymerase clamp coiled-coil motif.
Nucleic Acids Res., 38, 2010

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件を2024-09-04に公開中

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