3OS0

PFV strand transfer complex (STC) at 2.81 A resolution

Summary for 3OS0

• Entry DOI: 10.2210/pdb3os0/pdb
• Related: 3L2R 3OS1 3OS2
• Descriptor: Integrase, DNA (5'-D(*AP*TP*TP*GP*TP*CP*AP*TP*GP*GP*AP*AP*TP*TP*TP*CP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*GP*AP*AP*AP*TP*TP*CP*CP*AP*TP*GP*AP*CP*A)-3'), ... (8 entities in total)
• Functional Keywords: protein-dna complex, tetramer, dna integration, endonuclease, metal-binding, multifunctional enzyme, nuclease, nucleotidyltransferase, nucleus, transferase, viral nucleoprotein, virion, dna-binding, zinc binding, hhcc motif, viral protein, recombination, recombination-dna complex, recombination/dna
• Biological source: Human spumaretrovirus; More
• Cellular location: Integrase: Virion (Potential). Protease/Reverse transcriptase/ribonuclease H: Host nucleus (By similarity): P14350
• Total number of polymer chains: 6
• Total formula weight: 109239.55

Authors

Maertens, G.N.,Hare, S.,Cherepanov, P. (deposition date: 2010-09-08, release date: 2010-11-17, Last modification date: 2023-11-01)

• Primary citation: Maertens, G.N.,Hare, S.,Cherepanov, P.; The mechanism of retroviral integration from X-ray structures of its key intermediates; Nature, 468:326-329, 2010; PubMed: 21068843; DOI: 10.1038/nature09517

Experimental method

X-RAY DIFFRACTION (2.81 Å)