7WTR
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![BU of 7wtr by Molmil](/molmil-images/mine/7wtr) | Cryo-EM structure of a yeast pre-40S ribosomal subunit - State Tsr1-3 | 分子名称: | 18S rRNA, 18S rRNA (guanine(1575)-N(7))-methyltransferase, 40S ribosomal protein S1-A, ... | 著者 | Cheng, J, Lau, B, Thoms, M, Ameismeier, M, Berninghausen, O, Hurt, E, Beckmann, R. | 登録日 | 2022-02-05 | 公開日 | 2022-10-19 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | The nucleoplasmic phase of pre-40S formation prior to nuclear export. Nucleic Acids Res., 50, 2022
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6GC0
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![BU of 6gc0 by Molmil](/molmil-images/mine/6gc0) | 50S ribosomal subunit assembly intermediate state 4 | 分子名称: | 23S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | 著者 | Nikolay, R, Hilal, T, Qin, B, Loerke, J, Buerger, J, Mielke, T, Spahn, C.M.T. | 登録日 | 2018-04-16 | 公開日 | 2018-06-20 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structural Visualization of the Formation and Activation of the 50S Ribosomal Subunit during In Vitro Reconstitution. Mol. Cell, 70, 2018
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4YY3
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![BU of 4yy3 by Molmil](/molmil-images/mine/4yy3) | 30S ribosomal subunit- HigB complex | 分子名称: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | 著者 | Schureck, M.A, Maehigashi, T, Dunham, C.M. | 登録日 | 2015-03-23 | 公開日 | 2016-07-06 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | mRNA bound to the 30S subunit is a HigB toxin substrate. Rna, 22, 2016
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7W1Z
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![BU of 7w1z by Molmil](/molmil-images/mine/7w1z) | Active state CI from Rotenone-NADH dataset, Subclass 2 | 分子名称: | (2R,6aS,12aS)-8,9-dimethoxy-2-(prop-1-en-2-yl)-1,2,12,12a-tetrahydrofuro[2',3':7,8][1]benzopyrano[2,3-c][1]benzopyran-6(6aH)-one, (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ... | 著者 | Gu, J.K, Yang, M.J. | 登録日 | 2021-11-21 | 公開日 | 2023-01-18 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | The coupling mechanism of mammalian mitochondrial complex I. Nat.Struct.Mol.Biol., 29, 2022
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6HIX
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![BU of 6hix by Molmil](/molmil-images/mine/6hix) | Cryo-EM structure of the Trypanosoma brucei mitochondrial ribosome - This entry contains the large mitoribosomal subunit | 分子名称: | 12S rRNA, 50S ribosomal protein L13, putative, ... | 著者 | Ramrath, D.J.F, Niemann, M, Leibundgut, M, Bieri, P, Prange, C, Horn, K, Leitner, A, Boehringer, D, Schneider, A, Ban, N. | 登録日 | 2018-08-31 | 公開日 | 2018-09-26 | 最終更新日 | 2019-02-06 | 実験手法 | ELECTRON MICROSCOPY (3.39 Å) | 主引用文献 | Evolutionary shift toward protein-based architecture in trypanosomal mitochondrial ribosomes. Science, 362, 2018
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6R6P
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![BU of 6r6p by Molmil](/molmil-images/mine/6r6p) | Structure of XBP1u-paused ribosome nascent chain complex (rotated state) | 分子名称: | 18S rRNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... | 著者 | Shanmuganathan, V, Cheng, J, Berninghausen, O, Beckmann, R. | 登録日 | 2019-03-27 | 公開日 | 2019-07-10 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural and mutational analysis of the ribosome-arresting human XBP1u. Elife, 8, 2019
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7W4F
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![BU of 7w4f by Molmil](/molmil-images/mine/7w4f) | Active state CI from Q1-NADH dataset, Subclass 4 | 分子名称: | (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ... | 著者 | Gu, J, Yang, M. | 登録日 | 2021-11-27 | 公開日 | 2023-01-25 | 最終更新日 | 2023-06-28 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | The coupling mechanism of mammalian mitochondrial complex I. Nat.Struct.Mol.Biol., 29, 2022
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1NOH
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![BU of 1noh by Molmil](/molmil-images/mine/1noh) | The structure of bacteriophage phi29 scaffolding protein gp7 after prohead assembly | 分子名称: | HEAD MORPHOGENESIS PROTEIN | 著者 | Morais, M.C, Kanamaru, S, Badasso, M.O, Koti, J.S, Owen, B.L, McMurray, C.T, L Anderson, D, Rossmann, M.G. | 登録日 | 2003-01-16 | 公開日 | 2003-07-01 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Bacteriophage f29 scaffolding protein gp7 before and after prohead assembly Nat.Struct.Biol., 10, 2003
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6R5Q
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![BU of 6r5q by Molmil](/molmil-images/mine/6r5q) | Structure of XBP1u-paused ribosome nascent chain complex (post-state) | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... | 著者 | Shanmuganathan, V, Cheng, J, Berninghausen, O, Beckmann, R. | 登録日 | 2019-03-25 | 公開日 | 2019-07-10 | 最終更新日 | 2019-10-30 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural and mutational analysis of the ribosome-arresting human XBP1u. Elife, 8, 2019
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6HL0
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![BU of 6hl0 by Molmil](/molmil-images/mine/6hl0) | Crystal Structure of Farnesoid X receptor (FXR) with bound NCoA-2 peptide | 分子名称: | Bile acid receptor, NCoA-2 peptide (Nuclear receptor coactivator 2), LYS-GLU-ASN-ALA-LEU-LEU-ARG-TYR-LEU-LEU-ASP-LYS-ASP | 著者 | Kudlinzki, D, Merk, D, Linhard, V.L, Saxena, K, Schubert-Zsilavecz, M, Schwalbe, H. | 登録日 | 2018-09-10 | 公開日 | 2019-05-29 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | 主引用文献 | Molecular tuning of farnesoid X receptor partial agonism. Nat Commun, 10, 2019
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7W1Y
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![BU of 7w1y by Molmil](/molmil-images/mine/7w1y) | Human MCM double hexamer bound to natural DNA duplex (polyAT/polyTA) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DNA (49-MER), ... | 著者 | Li, J, Dong, J, Dang, S, Zhai, Y. | 登録日 | 2021-11-21 | 公開日 | 2023-02-08 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (2.59 Å) | 主引用文献 | The human pre-replication complex is an open complex. Cell, 186, 2023
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3J7Y
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![BU of 3j7y by Molmil](/molmil-images/mine/3j7y) | Structure of the large ribosomal subunit from human mitochondria | 分子名称: | 16S rRNA, ADENOSINE MONOPHOSPHATE, CRIF1, ... | 著者 | Brown, A, Amunts, A, Bai, X.C, Sugimoto, Y, Edwards, P.C, Murshudov, G, Scheres, S.H.W, Ramakrishnan, V. | 登録日 | 2014-08-26 | 公開日 | 2014-10-15 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structure of the large ribosomal subunit from human mitochondria. Science, 346, 2014
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6R70
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![BU of 6r70 by Molmil](/molmil-images/mine/6r70) | Endogeneous native human 20S proteasome | 分子名称: | Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, ... | 著者 | Schmidli, C, Albiez, S, Rima, L, Righetto, R, Mohammed, I, Oliva, P, Kovacik, L, Stahlberg, H, Braun, T. | 登録日 | 2019-03-28 | 公開日 | 2019-07-03 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Microfluidic protein isolation and sample preparation for high-resolution cryo-EM. Proc.Natl.Acad.Sci.USA, 116, 2019
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3M2M
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![BU of 3m2m by Molmil](/molmil-images/mine/3m2m) | |
3HKZ
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![BU of 3hkz by Molmil](/molmil-images/mine/3hkz) | |
6RSL
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![BU of 6rsl by Molmil](/molmil-images/mine/6rsl) | |
7X8X
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![BU of 7x8x by Molmil](/molmil-images/mine/7x8x) | structural insights into Mycobacterium tuberculosis ClpP1P2 inhibition by Cediranib: implications for developing antimicrobial agents targeting Clp protease | 分子名称: | 4-[1-[3-[4-[(4-fluoranyl-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-quinazolin-7-yl]oxypropyl]piperidin-4-yl]benzamide, 4-[[3,5-bis(fluoranyl)phenyl]methyl]-N-[(4-bromophenyl)methyl]piperazine-1-carboxamide, ATP-dependent Clp protease proteolytic subunit 1, ... | 著者 | Bao, R, Luo, Y.F, Zhu, Y.B, Yang, Y, Zhou, Y.Z. | 登録日 | 2022-03-15 | 公開日 | 2023-04-12 | 最終更新日 | 2024-04-24 | 実験手法 | X-RAY DIFFRACTION (3.24 Å) | 主引用文献 | Discovery and Mechanistic Study of Novel Mycobacterium tuberculosis ClpP1P2 Inhibitors J.Med.Chem., 66, 2023
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6HCJ
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![BU of 6hcj by Molmil](/molmil-images/mine/6hcj) | Structure of the rabbit 80S ribosome on globin mRNA in the rotated state with A/P and P/E tRNAs | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... | 著者 | Juszkiewicz, S, Chandrasekaran, V, Lin, Z, Kraatz, S, Ramakrishnan, V, Hegde, R.S. | 登録日 | 2018-08-15 | 公開日 | 2018-10-17 | 最終更新日 | 2018-11-14 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | ZNF598 Is a Quality Control Sensor of Collided Ribosomes. Mol. Cell, 72, 2018
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1MLZ
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![BU of 1mlz by Molmil](/molmil-images/mine/1mlz) | Crystal Structure of 7,8-Diaminopelargonic Acid Synthase in complex with the trans-isomer of amiclenomycin. | 分子名称: | 7,8-diamino-pelargonic acid aminotransferase, PYRIDOXAL-5'-PHOSPHATE, SODIUM ION, ... | 著者 | Sandmark, J, Mann, S, Marquet, A, Schneider, G. | 登録日 | 2002-09-02 | 公開日 | 2002-12-04 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Structural basis for the inhibition of the biosynthesis of biotin by the antibiotic amiclenomycin J.Biol.Chem., 277, 2002
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6HCQ
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![BU of 6hcq by Molmil](/molmil-images/mine/6hcq) | Structure of the rabbit collided di-ribosome (collided monosome) | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... | 著者 | Juszkiewicz, S, Chandrasekaran, V, Lin, Z, Kraatz, S, Ramakrishnan, V, Hegde, R.S. | 登録日 | 2018-08-16 | 公開日 | 2018-10-17 | 最終更新日 | 2018-11-14 | 実験手法 | ELECTRON MICROSCOPY (6.5 Å) | 主引用文献 | ZNF598 Is a Quality Control Sensor of Collided Ribosomes. Mol. Cell, 72, 2018
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7XFN
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![BU of 7xfn by Molmil](/molmil-images/mine/7xfn) | Structure of nucleosome-DI complex (-55I, Apo state) | 分子名称: | DNA (152-MER), Histone H2A type 1, Histone H2B 1.1, ... | 著者 | Zheng, L, Tsai, B, Gao, N. | 登録日 | 2022-04-01 | 公開日 | 2023-04-19 | 最終更新日 | 2023-11-08 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structural and mechanistic insights into the DNA glycosylase AAG-mediated base excision in nucleosome. Cell Discov, 9, 2023
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7XFL
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![BU of 7xfl by Molmil](/molmil-images/mine/7xfl) | Structure of nucleosome-AAG complex (A-53I, free state) | 分子名称: | DNA (152-MER), Histone H2A type 1, Histone H2B 1.1, ... | 著者 | Zheng, L, Tsai, B, Gao, N. | 登録日 | 2022-04-01 | 公開日 | 2023-04-19 | 最終更新日 | 2023-11-08 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structural and mechanistic insights into the DNA glycosylase AAG-mediated base excision in nucleosome. Cell Discov, 9, 2023
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7XFH
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![BU of 7xfh by Molmil](/molmil-images/mine/7xfh) | Structure of nucleosome-AAG complex (A-30I, post-catalytic state) | 分子名称: | DNA (152-MER), DNA-3-methyladenine glycosylase, Histone H2A type 1, ... | 著者 | Zheng, L, Tsai, B, Gao, N. | 登録日 | 2022-04-01 | 公開日 | 2023-04-19 | 最終更新日 | 2023-11-08 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural and mechanistic insights into the DNA glycosylase AAG-mediated base excision in nucleosome. Cell Discov, 9, 2023
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7XFM
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![BU of 7xfm by Molmil](/molmil-images/mine/7xfm) | Structure of nucleosome-AAG complex (A-53I, post-catalytic state) | 分子名称: | DNA (152-MER), DNA-3-methyladenine glycosylase, Histone H2A type 1, ... | 著者 | Zheng, L, Tsai, B, Gao, N. | 登録日 | 2022-04-01 | 公開日 | 2023-04-19 | 最終更新日 | 2023-11-08 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural and mechanistic insights into the DNA glycosylase AAG-mediated base excision in nucleosome. Cell Discov, 9, 2023
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7XFC
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![BU of 7xfc by Molmil](/molmil-images/mine/7xfc) | Structure of nucleosome-DI complex (-30I, Apo state) | 分子名称: | DNA (152-MER), Histone H2A type 1, Histone H2B 1.1, ... | 著者 | Zheng, L, Tsai, B, Gao, N. | 登録日 | 2022-04-01 | 公開日 | 2023-04-19 | 最終更新日 | 2023-11-08 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural and mechanistic insights into the DNA glycosylase AAG-mediated base excision in nucleosome. Cell Discov, 9, 2023
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