7MT8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7mt8 by Molmil](/molmil-images/mine/7mt8) | Rhodopsin kinase (GRK1)-S5E/S488E/T489E in complex with rhodopsin | 分子名称: | RETINAL, Rhodopsin, Rhodopsin kinase GRK1, ... | 著者 | Chen, Q, Chen, C.-L, Tesmer, J.J.G. | 登録日 | 2021-05-13 | 公開日 | 2021-07-07 | 最終更新日 | 2021-08-25 | 実験手法 | ELECTRON MICROSCOPY (5.8 Å) | 主引用文献 | Structures of rhodopsin in complex with G-protein-coupled receptor kinase 1. Nature, 595, 2021
|
|
7MIX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7mix by Molmil](/molmil-images/mine/7mix) | Human N-type voltage-gated calcium channel Cav2.2 in the presence of ziconotide at 3.0 Angstrom resolution | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Yan, N, Gao, S, Yao, X. | 登録日 | 2021-04-18 | 公開日 | 2021-07-07 | 最終更新日 | 2021-08-18 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structure of human Ca v 2.2 channel blocked by the painkiller ziconotide. Nature, 596, 2021
|
|
7MIY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7miy by Molmil](/molmil-images/mine/7miy) | Human N-type voltage-gated calcium channel Cav2.2 at 3.1 Angstrom resolution | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Yan, N, Gao, S, Yao, X. | 登録日 | 2021-04-18 | 公開日 | 2021-07-07 | 最終更新日 | 2021-08-18 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structure of human Ca v 2.2 channel blocked by the painkiller ziconotide. Nature, 596, 2021
|
|
7MTA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7mta by Molmil](/molmil-images/mine/7mta) | Rhodopsin kinase (GRK1)-S5E/S488E/T489E in complex with rhodopsin and Fab1 | 分子名称: | Fab1 Heavy chain, Fab1 Light chain, RETINAL, ... | 著者 | Chen, Q, Chen, C.-L, Tesmer, J.J.G. | 登録日 | 2021-05-13 | 公開日 | 2021-07-07 | 最終更新日 | 2021-08-25 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structures of rhodopsin in complex with G-protein-coupled receptor kinase 1. Nature, 595, 2021
|
|
7MT9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7mt9 by Molmil](/molmil-images/mine/7mt9) | Rhodopsin kinase (GRK1) in complex with rhodopsin | 分子名称: | RETINAL, Rhodopsin, Rhodopsin kinase GRK1, ... | 著者 | Chen, Q, Chen, C.-L, Tesmer, J.J.G. | 登録日 | 2021-05-13 | 公開日 | 2021-07-07 | 最終更新日 | 2021-08-25 | 実験手法 | ELECTRON MICROSCOPY (7 Å) | 主引用文献 | Structures of rhodopsin in complex with G-protein-coupled receptor kinase 1. Nature, 595, 2021
|
|
4ER3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4er3 by Molmil](/molmil-images/mine/4er3) | Crystal Structure of Human DOT1L in complex with inhibitor EPZ004777 | 分子名称: | 1,2-ETHANEDIOL, 7-{5-[(3-{[(4-tert-butylphenyl)carbamoyl]amino}propyl)(propan-2-yl)amino]-5-deoxy-beta-D-ribofuranosyl}-7H-pyrrolo[2,3-d]pyrimidin-4-amine, Histone-lysine N-methyltransferase, ... | 著者 | Wernimont, A.K, Tempel, W, Yu, W, Scopton, A, Li, Y, Nguyen, K.T, Federation, A, Marineau, J, Qi, J, Vedadi, M, Bradner, J.E, Schapira, M, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Brown, P.J, Structural Genomics Consortium (SGC) | 登録日 | 2012-04-19 | 公開日 | 2012-05-16 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors. Nat Commun, 3, 2012
|
|
4E3Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4e3y by Molmil](/molmil-images/mine/4e3y) | X-ray structure of the Serratia marcescens endonuclease at 0.95 A resolution | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | 著者 | Lashkov, A.A, Balaev, V.V, Gabdoulkhakov, A.G, Betzel, C, Mikhailov, A.M. | 登録日 | 2012-03-11 | 公開日 | 2013-05-08 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (0.95 Å) | 主引用文献 | X-ray structure of the Serratia marcescens endonuclease at 0.95 A resolution To be Published
|
|
4E4D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4e4d by Molmil](/molmil-images/mine/4e4d) | Crystal structure of mouse RANKL-OPG complex | 分子名称: | CHLORIDE ION, Tumor necrosis factor ligand superfamily member 11, soluble form, ... | 著者 | Nelson, C.A, Fremont, D.H. | 登録日 | 2012-03-12 | 公開日 | 2012-10-24 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | RANKL Employs Distinct Binding Modes to Engage RANK and the Osteoprotegerin Decoy Receptor. Structure, 20, 2012
|
|
4E4S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4e4s by Molmil](/molmil-images/mine/4e4s) | Crystal structure of Pika GITRL | 分子名称: | GLYCEROL, MAGNESIUM ION, Tumor necrosis factor ligand superfamily member 18 | 著者 | Kumar, P.R, Bhosle, R, Bonanno, J, Chowdhury, S, Gizzi, A, Glen, S, Hillerich, B, Hammonds, J, Seidel, R, Toro, R, Nathenson, S.G, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN) | 登録日 | 2012-03-13 | 公開日 | 2012-03-21 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Crystal structure of GITRL from Ochotona princeps to be published
|
|
4E5C
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4e5c by Molmil](/molmil-images/mine/4e5c) | |
4E5H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4e5h by Molmil](/molmil-images/mine/4e5h) | Crystal structure of avian influenza virus PAn bound to compound 3 | 分子名称: | (2Z)-4-[1-benzyl-4-(4-chlorobenzyl)piperidin-4-yl]-2-hydroxy-4-oxobut-2-enoic acid, MANGANESE (II) ION, Polymerase protein PA, ... | 著者 | DuBois, R.M, Slavish, P.J, Webb, T.R, White, S.W. | 登録日 | 2012-03-14 | 公開日 | 2012-08-08 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.158 Å) | 主引用文献 | Structural and Biochemical Basis for Development of Influenza Virus Inhibitors Targeting the PA Endonuclease. Plos Pathog., 8, 2012
|
|
4E5R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4e5r by Molmil](/molmil-images/mine/4e5r) | Crystal Structure of Frog DGCR8 Dimerization Domain | 分子名称: | MGC78846 protein | 著者 | Guo, F, Senturia, R, Laganowsky, A, Barr, I, Scheidemantle, B.D. | 登録日 | 2012-03-14 | 公開日 | 2013-02-27 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Dimerization and heme binding are conserved in amphibian and starfish homologues of the microRNA processing protein DGCR8. Plos One, 7, 2012
|
|
4E5T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4e5t by Molmil](/molmil-images/mine/4e5t) | Crystal structure of a putative Mandelate racemase/Muconate lactonizing enzyme (Target PSI-200750) from Labrenzia alexandrii DFL-11 | 分子名称: | MAGNESIUM ION, Mandelate racemase / muconate lactonizing enzyme, C-terminal domain protein | 著者 | Kumar, P.R, Bonanno, J, Chowdhury, S, Foti, R, Gizzi, A, Glen, S, Hammonds, J, Hillerich, B, Matikainen, B, Seidel, R, Toro, R, Zencheck, W, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) | 登録日 | 2012-03-14 | 公開日 | 2012-03-28 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystal structure of a putative MR/ML enzyme from Labrenzia alexandrii DFL-11 to be published
|
|
7M4T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7m4t by Molmil](/molmil-images/mine/7m4t) | Menin bound to M-1121 | 分子名称: | Menin, methyl {(1S,2R)-2-[(1S)-2-(azetidin-1-yl)-1-(3-fluorophenyl)-1-{1-[(3-methoxy-1-{4-[(1S,4S)-5-propanoyl-2,5-diazabicyclo[2.2.1]heptane-2-sulfonyl]phenyl}azetidin-3-yl)methyl]piperidin-4-yl}ethyl]cyclopentyl}carbamate, praseodymium triacetate | 著者 | Stuckey, J. | 登録日 | 2021-03-22 | 公開日 | 2021-08-11 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.74 Å) | 主引用文献 | Discovery of M-1121 as an Orally Active Covalent Inhibitor of Menin-MLL Interaction Capable of Achieving Complete and Long-Lasting Tumor Regression. J.Med.Chem., 64, 2021
|
|
4EUW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4euw by Molmil](/molmil-images/mine/4euw) | |
4EEC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4eec by Molmil](/molmil-images/mine/4eec) | |
4EYA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4eya by Molmil](/molmil-images/mine/4eya) | Crystal Structure of a Plectonemic RNA Supercoil | 分子名称: | GLYCEROL, N utilization substance protein B homolog, RNA (5'-R(*GP*GP*CP*UP*CP*CP*UP*UP*GP*GP*CP*A)-3'), ... | 著者 | Stagno, J.R, Ji, X. | 登録日 | 2012-05-01 | 公開日 | 2012-06-20 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Crystal structure of a plectonemic RNA supercoil. Nat Commun, 3, 2012
|
|
7LBM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7lbm by Molmil](/molmil-images/mine/7lbm) | Structure of the human Mediator-bound transcription pre-initiation complex | 分子名称: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | 著者 | Abdella, R, Talyzina, A, He, Y. | 登録日 | 2021-01-08 | 公開日 | 2021-03-24 | 最終更新日 | 2021-04-14 | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | 主引用文献 | Structure of the human Mediator-bound transcription preinitiation complex. Science, 372, 2021
|
|
4E4Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4e4z by Molmil](/molmil-images/mine/4e4z) | |
4EFD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4efd by Molmil](/molmil-images/mine/4efd) | Crystal Structure of an M17 aminopeptidase from Trypanosoma Brucei, Tb427tmp.02.4440 | 分子名称: | Aminopeptidase, GLYCEROL, MANGANESE (II) ION, ... | 著者 | Wernimont, A.K, Osman, K.T, Loppnau, P, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Hui, R, Lin, Y.H, Structural Genomics Consortium (SGC) | 登録日 | 2012-03-29 | 公開日 | 2012-05-30 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Crystal Structure of an M17 aminopeptidase from Trypanosoma Brucei, Tb427tmp.02.4440 To be Published
|
|
4E69
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4e69 by Molmil](/molmil-images/mine/4e69) | Crystal structure of a sugar kinase (target EFI-502132) from Oceanicola granulosus, unliganded structure | 分子名称: | 1,2-ETHANEDIOL, 2-dehydro-3-deoxygluconokinase, CHLORIDE ION, ... | 著者 | Vetting, M.W, Toro, R, Bhosle, R, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | 登録日 | 2012-03-15 | 公開日 | 2012-04-18 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystal structure of a sugar kinase (target EFI-502132) from Oceanicola granulosus, unliganded structure To be Published
|
|
4EH5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4eh5 by Molmil](/molmil-images/mine/4eh5) | Human p38 MAP kinase in complex with NP-F4 and RL87 | 分子名称: | Mitogen-activated protein kinase 14, N~4~-cyclopropyl-2-phenylquinazoline-4,7-diamine, benzyl pyridine-3-carboxylate | 著者 | Over, B, Gruetter, C, Waldmann, H, Rauh, D. | 登録日 | 2012-04-02 | 公開日 | 2012-12-05 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Natural-product-derived fragments for fragment-based ligand discovery. Nat Chem, 5, 2012
|
|
4E70
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4e70 by Molmil](/molmil-images/mine/4e70) | Crystal Structure Analysis of Coniferyl Alcohol 9-O-Methyltransferase from Linum Nodiflorum in Complex with Coniferyl Alcohol | 分子名称: | 4-[(1E)-3-hydroxyprop-1-en-1-yl]-2-methoxyphenol, Coniferyl alcohol 9-O-methyltransferase, GLYCEROL | 著者 | Wolters, S, Heine, A, Petersen, M. | 登録日 | 2012-03-16 | 公開日 | 2013-05-01 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.6093 Å) | 主引用文献 | Structural analysis of coniferyl alcohol 9-O-methyltransferase from Linum nodiflorum reveals a novel active-site environment. Acta Crystallogr.,Sect.D, 69, 2013
|
|
4EHX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ehx by Molmil](/molmil-images/mine/4ehx) | Crystal structure of LpxK from Aquifex aeolicus at 1.9 angstrom resolution | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, ... | 著者 | Emptage, R.P, Daughtry, K.D, Pemble IV, C.W, Raetz, C.R.H. | 登録日 | 2012-04-04 | 公開日 | 2012-08-29 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of LpxK, the 4'-kinase of lipid A biosynthesis and atypical P-loop kinase functioning at the membrane interface. Proc.Natl.Acad.Sci.USA, 109, 2012
|
|
4EI9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ei9 by Molmil](/molmil-images/mine/4ei9) | Crystal structure of Bacillus cereus TubZ, GTP-form | 分子名称: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, Plasmid replication protein RepX | 著者 | Hayashi, I, Hoshino, S. | 登録日 | 2012-04-05 | 公開日 | 2012-08-15 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Filament formation of the FtsZ/tubulin-like protein TubZ from the Bacillus cereus pXO1 plasmid. J.Biol.Chem., 287, 2012
|
|