8HCY
 
 | | Legionella glycosyltransferase | | 分子名称: | Dot/Icm secretion system substrate | | 著者 | Chen, T.T, Ouyang, S.Y. | | 登録日 | 2022-11-03 | | 公開日 | 2023-11-08 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | | 主引用文献 | Structural Basis for the Action Mechanism of Legionella Glycosyltransferase.
Small Struct, 2023
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2V73
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4WGK
 | | Crystal structure of human neutral ceramidase with Zn-bound phosphate | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Airola, M.V, Pulkoski-Gross, M.J, Obeid, L.M, Hannun, Y.A. | | 登録日 | 2014-09-18 | | 公開日 | 2015-07-08 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.582 Å) | | 主引用文献 | Structural Basis for Ceramide Recognition and Hydrolysis by Human Neutral Ceramidase.
Structure, 23, 2015
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2V7N
 | | Unusual twinning in crystals of the CitS binding antibody Fab fragment f3p4 | | 分子名称: | IMMUNOGLOBULIN HEAVY CHAIN, IMMUNOGLOBULIN LIGHT CHAIN | | 著者 | Frey, D, Huber, T, Plueckthun, A, Gruetter, M.G. | | 登録日 | 2007-07-31 | | 公開日 | 2008-06-17 | | 最終更新日 | 2019-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | Structure of the Recombinant Antibody Fab Fragment F3P4.
Acta Crystallogr.,Sect.D, 64, 2008
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8HES
 | | Crystal structure of SARS-CoV-2 RBD and NIV-10 complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, NIV-10 Fab H-chain, NIV-10 Fab L-chain, ... | | 著者 | Moriyama, S, Anraku, Y, Taminishi, S, Adachi, Y, Kuroda, D, Higuchi, Y, Kotaki, R, Tonouchi, K, Yumoto, K, Suzuki, T, Kita, S, Someya, T, Fukuhara, H, Kuroda, Y, Yamamoto, T, Onodera, T, Fukushi, S, Maeda, K, Nakamura-Uchiyama, F, Hashiguchi, T, Hoshino, A, Maenaka, K, Takahashi, Y. | | 登録日 | 2022-11-08 | | 公開日 | 2023-11-08 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural delineation and computational design of SARS-CoV-2-neutralizing antibodies against Omicron subvariants.
Nat Commun, 14, 2023
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4WIJ
 | | HUMAN SPLICING FACTOR, CONSTRUCT 1 | | 分子名称: | Splicing factor, proline- and glutamine-rich | | 著者 | lee, M, bond, c.s. | | 登録日 | 2014-09-26 | | 公開日 | 2015-04-01 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (3.49 Å) | | 主引用文献 | The structure of human SFPQ reveals a coiled-coil mediated polymer essential for functional aggregation in gene regulation.
Nucleic Acids Res., 43, 2015
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8H4F
 | | Blasnase-T13A/P55F with D-asn | | 分子名称: | D-ASPARAGINE, FORMIC ACID, L-asparaginase, ... | | 著者 | Lu, F, Wang, W, Chi, H, Ran, T. | | 登録日 | 2022-10-10 | | 公開日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure-based rational design of Bacillus licheniformis L-asparaginase with low/no D-asparaginase activity for a safer enzyme
To Be Published
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2V9T
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4WIU
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8HCE
 | | Crystal structure of mTREX1-CMP complex | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, AMMONIUM ION, CYTIDINE-5'-MONOPHOSPHATE, ... | | 著者 | Hsiao, Y.Y, Huang, K.W, Wu, C.Y. | | 登録日 | 2022-11-01 | | 公開日 | 2023-11-08 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.501 Å) | | 主引用文献 | Molecular insight into the specific enzymatic properties of TREX1 revealing the diverse functions in processing RNA and DNA/RNA hybrids.
Nucleic Acids Res., 51, 2023
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2VCL
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4WJ5
 | | Structure of HLA-A2 in complex with an altered peptide ligands based on Mart-1 variant epitope | | 分子名称: | Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... | | 著者 | Celie, P.H.N, Rodenko, B, Ovaa, H. | | 登録日 | 2014-09-29 | | 公開日 | 2014-10-29 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Altered Peptide Ligands Revisited: Vaccine Design through Chemically Modified HLA-A2-Restricted T Cell Epitopes.
J Immunol., 193, 2014
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2V6I
 | | Kokobera Virus Helicase | | 分子名称: | PYROPHOSPHATE 2-, RNA HELICASE | | 著者 | Speroni, S, De Colibus, L, Coutard, B, Canard, B, Mattevi, A. | | 登録日 | 2007-07-18 | | 公開日 | 2008-03-25 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure and Biochemical Analysis of Kokobera Virus Helicase
Proteins: Struct., Funct., Bioinf., 70, 2008
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8HE7
 | | ADP-ribosyltransferase 1 (PARP1) catalytic domain bound to a quinazoline-2,4(1H,3H)-dione inhibitor | | 分子名称: | 1-[[4-fluoranyl-3-(3-oxidanylidene-4-pentan-3-yl-piperazin-1-yl)carbonyl-phenyl]methyl]quinazoline-2,4-dione, Poly [ADP-ribose] polymerase 1, processed C-terminus, ... | | 著者 | Wang, X.Y, Zhou, J, Xu, B.L. | | 登録日 | 2022-11-07 | | 公開日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Discovery of Quinazoline-2,4(1 H ,3 H )-dione Derivatives Containing a Piperizinone Moiety as Potent PARP-1/2 Inhibitors─Design, Synthesis, In Vivo Antitumor Activity, and X-ray Crystal Structure Analysis.
J.Med.Chem., 66, 2023
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4WJM
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4WJQ
 | | Crystal Structure of SUMO1 in complex with Daxx | | 分子名称: | Daxx, Small ubiquitin-related modifier 1 | | 著者 | Cappadocia, L, Mascle, X.H, Bourdeau, V, Tremblay-Belzile, S, Chaker-Margot, M, Lussier-Price, M, Wada, J, Sakaguchi, K, Aubry, M, Ferbeyre, G, Omichinski, J.G. | | 登録日 | 2014-10-01 | | 公開日 | 2014-12-31 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Structural and Functional Characterization of the Phosphorylation-Dependent Interaction between PML and SUMO1.
Structure, 23, 2015
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2VFD
 | | Crystal structure of the F96S mutant of Plasmodium falciparum triosephosphate isomerase | | 分子名称: | SULFATE ION, TRIOSEPHOSPHATE ISOMERASE | | 著者 | Gayathri, P, Banerjee, M, Vijayalakshmi, A, Balaram, H, Balaram, P, Murthy, M.R.N. | | 登録日 | 2007-11-03 | | 公開日 | 2008-12-09 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Biochemical and Structural Characterization of Residue 96 Mutants of Plasmodium Falciparum Triosephosphate Isomerase: Active-Site Loop Conformation, Hydration and Identification of a Dimer-Interface Ligand-Binding Site.
Acta Crystallogr.,Sect.D, 65, 2009
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8HGF
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8HCJ
 | | Structure of GH43 family enzyme, Xylan 1, 4 Beta- xylosidase from pseudopedobacter saltans | | 分子名称: | CALCIUM ION, Xylan 1,4-beta-xylosidase | | 著者 | Vishwakarma, P, Sachdeva, E, Goyal, A, Ethayathulla, A.S, Das, U, Kaur, P. | | 登録日 | 2022-11-01 | | 公開日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.566 Å) | | 主引用文献 | Structure of GH43 family enzyme, Xylan 1, 4 Beta- xylosidase from pseudopedobacter saltans
To Be Published
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2VL3
 | | Oxidized and reduced forms of human peroxiredoxin 5 | | 分子名称: | PEROXIREDOXIN-5 | | 著者 | Smeets, A, Declercq, J.P. | | 登録日 | 2008-01-08 | | 公開日 | 2008-08-26 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | The Crystal Structures of Oxidized Forms of Human Peroxiredoxin 5 with an Intramolecular Disulfide Bond Confirm the Proposed Enzymatic Mechanism for Atypical 2-Cys Peroxiredoxins.
Arch.Biochem.Biophys., 477, 2008
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4WJX
 | | Crystal structure of human chitotriosidase-1 catalytic domain at 1.0 A resolution | | 分子名称: | Chitotriosidase-1, L(+)-TARTARIC ACID | | 著者 | Fadel, F, Zhao, Y, Cachau, R, Cousido-Siah, A, Ruiz, F.X, Harlos, K, Howard, E, Mitschler, A, Podjarny, A. | | 登録日 | 2014-10-01 | | 公開日 | 2015-07-08 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (1 Å) | | 主引用文献 | New insights into the enzymatic mechanism of human chitotriosidase (CHIT1) catalytic domain by atomic resolution X-ray diffraction and hybrid QM/MM
Acta Crystallogr.,Sect.D, 71, 2015
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8HG7
 | | Structure of human SGLT2-MAP17 complex with Sotagliflozin | | 分子名称: | (2S,3R,4R,5S,6R)-2-[4-chloranyl-3-[(4-ethoxyphenyl)methyl]phenyl]-6-methylsulfanyl-oxane-3,4,5-triol, 2-acetamido-2-deoxy-beta-D-glucopyranose, PDZK1-interacting protein 1, ... | | 著者 | Hiraizumi, M, Kishida, H, Miyaguchi, I, Nureki, O. | | 登録日 | 2022-11-14 | | 公開日 | 2023-11-15 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Transport and inhibition mechanism of the human SGLT2-MAP17 glucose transporter.
Nat.Struct.Mol.Biol., 31, 2024
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4WK5
 | | Crystal structure of a Isoprenoid Synthase family member from Thermotoga neapolitana DSM 4359, target EFI-509458 | | 分子名称: | Geranyltranstransferase | | 著者 | Toro, R, Bhosle, R, Vetting, M.W, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Stead, M, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hillerich, B, Love, J, Seidel, R.D, Whalen, K.L, Gerlt, J.A, Poulter, C.D, Almo, S.C, Enzyme Function Initiative (EFI) | | 登録日 | 2014-10-01 | | 公開日 | 2014-11-19 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal structure of a Isoprenoid Synthase family member from Thermotoga neapolitana DSM 4359, target EFI-509458
To be published
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2VF3
 | | Aquifex aeolicus IspE in complex with ligand | | 分子名称: | 4-DIPHOSPHOCYTIDYL-2C-METHYL-D-ERYTHRITOL KINASE, BROMIDE ION, CHLORIDE ION, ... | | 著者 | Alphey, M.S, Hunter, W.N. | | 登録日 | 2007-10-30 | | 公開日 | 2008-11-25 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Inhibitors of the Kinase Ispe: Structure-Activity Relationships and Co-Crystal Structure Analysis.
Org.Biomol.Chem., 6, 2008
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8HCC
 | | Crystal structure of mTREX1-RNA product complex (AMP) | | 分子名称: | ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, SODIUM ION, ... | | 著者 | Hsiao, Y.Y, Huang, K.W, Wu, C.Y. | | 登録日 | 2022-11-01 | | 公開日 | 2023-11-08 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Molecular insight into the specific enzymatic properties of TREX1 revealing the diverse functions in processing RNA and DNA/RNA hybrids.
Nucleic Acids Res., 51, 2023
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