Loading
PDBj
メニューPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

8ADV
DownloadVisualize
BU of 8adv by Molmil
Lipidic alpha-synuclein fibril - polymorph L1B
分子名称: Alpha-synuclein
著者Frieg, B, Antonschmidt, L, Dienemann, C, Geraets, J.A, Najbauer, E.E, Matthes, D, de Groot, B.L, Andreas, L.B, Becker, S, Griesinger, C, Schroeder, G.F.
登録日2022-07-11
公開日2022-10-12
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (2.98 Å)
主引用文献The 3D structure of lipidic fibrils of alpha-synuclein.
Nat Commun, 13, 2022
8ADS
DownloadVisualize
BU of 8ads by Molmil
Lipidic alpha-synuclein fibril - polymorph L2B
分子名称: Alpha-synuclein
著者Frieg, B, Antonschmidt, L, Dienemann, C, Geraets, J.A, Najbauer, E.E, Matthes, D, de Groot, B.L, Andreas, L.B, Becker, S, Griesinger, C, Schroeder, G.F.
登録日2022-07-11
公開日2022-10-12
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (3.05 Å)
主引用文献The 3D structure of lipidic fibrils of alpha-synuclein.
Nat Commun, 13, 2022
8A4L
DownloadVisualize
BU of 8a4l by Molmil
Lipidic alpha-synuclein fibril - polymorph L2A
分子名称: Alpha-synuclein
著者Frieg, B, Antonschmidt, L, Dienemann, C, Geraets, J.A, Najbauer, E.E, Matthes, D, de Groot, B.L, Andreas, L.B, Becker, S, Griesinger, C, Schroeder, G.F.
登録日2022-06-12
公開日2022-08-17
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (2.68 Å)
主引用文献The 3D structure of lipidic fibrils of alpha-synuclein.
Nat Commun, 13, 2022
8HZC
DownloadVisualize
BU of 8hzc by Molmil
Formed alpha-synuclein fibrils after incubation with heparin for 1 hour (Hep-remod-2)
分子名称: Alpha-synuclein
著者Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D.
登録日2023-01-08
公開日2024-01-10
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Formed alpha-synuclein fibrils after incubation with heparin for 1 hour (Hep-remod-2)
To Be Published
8HZB
DownloadVisualize
BU of 8hzb by Molmil
Formed alpha-synuclein fibrils after incubation with heparin for 1 hour (Hep-remod-1)
分子名称: Alpha-synuclein
著者Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D.
登録日2023-01-08
公開日2024-01-10
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Formed alpha-synuclein fibrils after incubation with heparin for 1 hour (Hep-remod-1)
To Be Published
8HZS
DownloadVisualize
BU of 8hzs by Molmil
Formed alpha-synuclein fibrils after incubation with heparin for 3 days (Hep-remod-3)
分子名称: Alpha-synuclein
著者Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D.
登録日2023-01-09
公開日2024-01-10
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Formed alpha-synuclein fibrils after incubation with heparin for 3 days (Hep-remod-3)
To Be Published
8F1I
DownloadVisualize
BU of 8f1i by Molmil
SigN RNA polymerase early-melted intermediate bound to mismatch fragment dhsU36mm1 (-12T)
分子名称: DNA (36-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Mueller, A.U, Chen, J, Darst, S.A.
登録日2022-11-05
公開日2023-04-05
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献A general mechanism for transcription bubble nucleation in bacteria.
Proc.Natl.Acad.Sci.USA, 120, 2023
8F1J
DownloadVisualize
BU of 8f1j by Molmil
SigN RNA polymerase early-melted intermediate bound to mismatch DNA fragment dhsU36mm2 (-12A)
分子名称: DNA (36-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Mueller, A.U, Chen, J, Darst, S.A.
登録日2022-11-05
公開日2023-04-05
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献A general mechanism for transcription bubble nucleation in bacteria.
Proc.Natl.Acad.Sci.USA, 120, 2023
8F1K
DownloadVisualize
BU of 8f1k by Molmil
SigN RNA polymerase early-melted intermediate bound to full duplex DNA fragment dhsU36 (-12T)
分子名称: DNA (36-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Mueller, A.U, Chen, J, Darst, S.A.
登録日2022-11-05
公開日2023-04-05
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献A general mechanism for transcription bubble nucleation in bacteria.
Proc.Natl.Acad.Sci.USA, 120, 2023
9EUU
DownloadVisualize
BU of 9euu by Molmil
Structure of recombinant alpha-synuclein fibrils 1B capable of seeding GCIs in vivo
分子名称: Alpha-synuclein
著者Burger, D, Kashyrina, M, Lewis, A, De Nuccio, F, Mohammed, I, de La Seigliere, H, van den Heuvel, L, Feuillie, C, Verchere, J, Berbon, M, Arotcarena, M, Retailleau, A, Bezard, E, Laferriere, F, Loquet, A, Bousset, L, Baron, T, Lofrumento, D.D, De Giorgi, F, Stahlberg, H, Ichas, F.
登録日2024-03-28
公開日2024-06-05
実験手法ELECTRON MICROSCOPY (1.93 Å)
主引用文献Multiple System Atrophy: Insights from aSyn Fibril Structure
To Be Published
8JO2
DownloadVisualize
BU of 8jo2 by Molmil
Structural basis of transcriptional activation by the OmpR/PhoB-family response regulator PmrA
分子名称: DNA (65-MER), DNA-binding transcriptional regulator BasR, DNA-directed RNA polymerase subunit alpha, ...
著者Lou, Y.-C, Huang, H.-Y, Chen, C, Wu, K.-P.
登録日2023-06-06
公開日2023-08-30
最終更新日2023-10-25
実験手法ELECTRON MICROSCOPY (2.74 Å)
主引用文献Structural basis of transcriptional activation by the OmpR/PhoB-family response regulator PmrA.
Nucleic Acids Res., 51, 2023
6L1T
DownloadVisualize
BU of 6l1t by Molmil
Cryo-EM structure of phosphorylated Tyr39 a-synuclein amyloid fibril
分子名称: Alpha-synuclein
著者Liu, C, Li, Y.M, Zhao, K, Lim, Y.J, Liu, Z.Y.
登録日2019-09-30
公開日2020-08-12
最終更新日2020-09-02
実験手法ELECTRON MICROSCOPY (3.22 Å)
主引用文献Parkinson's disease-related phosphorylation at Tyr39 rearranges alpha-synuclein amyloid fibril structure revealed by cryo-EM.
Proc.Natl.Acad.Sci.USA, 117, 2020
6L1U
DownloadVisualize
BU of 6l1u by Molmil
Cryo-EM structure of phosphorylated Tyr39 alpha-synuclein amyloid fibril
分子名称: Alpha-synuclein
著者Liu, C, Li, Y.M, Zhao, K, Lim, Y.J, Liu, Z.Y.
登録日2019-09-30
公開日2020-08-12
最終更新日2020-09-02
実験手法ELECTRON MICROSCOPY (3.37 Å)
主引用文献Parkinson's disease-related phosphorylation at Tyr39 rearranges alpha-synuclein amyloid fibril structure revealed by cryo-EM.
Proc.Natl.Acad.Sci.USA, 117, 2020
6LRQ
DownloadVisualize
BU of 6lrq by Molmil
Cryo-EM structure of A53T alpha-synuclein amyloid fibril
分子名称: Alpha-synuclein
著者Sun, Y.P, Zhao, K, Liu, C.
登録日2020-01-16
公開日2020-04-08
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.49 Å)
主引用文献Cryo-EM structure of full-length alpha-synuclein amyloid fibril with Parkinson's disease familial A53T mutation.
Cell Res., 30, 2020
6E3K
DownloadVisualize
BU of 6e3k by Molmil
Interferon gamma signalling complex with IFNGR1 and IFNGR2
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Jude, K.M, Mendoza, J.L, Garcia, K.C.
登録日2018-07-14
公開日2019-02-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Structure of the IFN gamma receptor complex guides design of biased agonists.
Nature, 567, 2019
6E3L
DownloadVisualize
BU of 6e3l by Molmil
Interferon gamma signalling complex with IFNGR1 and IFNGR2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CYSTEINE, ...
著者Jude, K.M, Mendoza, J.L, Garcia, K.C.
登録日2018-07-14
公開日2019-02-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Structure of the IFN gamma receptor complex guides design of biased agonists.
Nature, 567, 2019
7V4B
DownloadVisualize
BU of 7v4b by Molmil
Heparin-induced alpha-synuclein fibrils polymorph 3
分子名称: Alpha-synuclein
著者Tao, Y.Q, Sun, Y.P, Liu, C, Li, D.
登録日2021-08-12
公開日2022-08-17
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Heparin-induced alpha-synuclein fibrils polymorph 3
To Be Published
7V4C
DownloadVisualize
BU of 7v4c by Molmil
Heparin-induced alpha-synuclein fibrils polymorph 4
分子名称: Alpha-synuclein
著者Tao, Y.Q, Sun, Y.P, Liu, C, Li, D.
登録日2021-08-12
公開日2022-08-17
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Heparin-induced alpha-synuclein fibrils polymorph 4
To Be Published
7V47
DownloadVisualize
BU of 7v47 by Molmil
Type 1A alpha-synuclein fibril seeded by cerebrospinal fluid from a preclinical Parkinson's disease patient
分子名称: Alpha-synuclein
著者Fan, Y, Sun, Y.P, Wang, J, Liu, C.
登録日2021-08-12
公開日2022-08-17
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease.
Structure, 31, 2023
7V48
DownloadVisualize
BU of 7v48 by Molmil
Type 1D alpha-synuclein fibril seeded by cerebrospinal fluid from a postmortal Parkinson's disease patient
分子名称: Alpha-synuclein
著者Fan, Y, Sun, Y.P, Wang, J, Liu, C.
登録日2021-08-12
公開日2022-08-17
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease.
Structure, 31, 2023
7V4A
DownloadVisualize
BU of 7v4a by Molmil
Heparin-induced alpha-synuclein fibrils polymorph 1
分子名称: Alpha-synuclein
著者Tao, Y.Q, Sun, Y.P, Liu, C, Li, D.
登録日2021-08-12
公開日2022-08-17
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Heparin-induced alpha-synuclein fibrils polymorph 1
To Be Published
7V4D
DownloadVisualize
BU of 7v4d by Molmil
Heparin-remodelled alpha-synuclein fibrils
分子名称: Alpha-synuclein
著者Tao, Y.Q, Sun, Y.P, Xia, W.C, Zhao, Q.Y, Liu, C, Li, D.
登録日2021-08-12
公開日2022-08-17
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Heparin-remodelled alpha-synuclein fibrils
To Be Published
7V49
DownloadVisualize
BU of 7v49 by Molmil
Type 4 alpha-synuclein fibril seeded by cerebrospinal fluid from a postmortal Parkinson's disease patient
分子名称: Alpha-synuclein
著者Fan, Y, Sun, Y.P, Wang, J, Liu, C.
登録日2021-08-12
公開日2022-08-17
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease.
Structure, 31, 2023
1XCV
DownloadVisualize
BU of 1xcv by Molmil
Crystal Structure Of (H79AC102D)Dtxr complexed with Nickel(II)
分子名称: Diphtheria toxin repressor mutant, NICKEL (II) ION
著者D'aquino, J.A, Ringe, D.
登録日2004-09-03
公開日2005-08-16
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Mechanism of metal ion activation of the diphtheria toxin repressor DtxR.
Proc.Natl.Acad.Sci.USA, 102, 2005
7C1D
DownloadVisualize
BU of 7c1d by Molmil
Cryo-EM structure of the hE46K cross-seeded hWT alpha-synuclein fibril
分子名称: Alpha-synuclein
著者Sun, Y.P, Zhao, K, Liu, C.
登録日2020-05-03
公開日2021-05-05
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Wild-type alpha-synuclein inherits the structure and exacerbated neuropathology of E46K mutant fibril strain by cross-seeding.
Proc.Natl.Acad.Sci.USA, 118, 2021

223532

件を2024-08-07に公開中

PDB statisticsPDBj update infoContact PDBjnumon