PDB: 205 件ウェブページステータス検索Chemie searchBIRD

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4BK1	Crystal structure of 3-hydroxybenzoate 6-hydroxylase uncovers lipid- assisted flavoprotein strategy for regioselective aromatic hydroxylation: H213S mutant in complex with 3-hydroxybenzoate 分子名称: 3-HYDROXYBENZOIC ACID, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Orru, R, Montersino, S, Barendregt, A, Westphal, A.H, van Duijn, E, Mattevi, A, van Berkel, W.J.H. 登録日 2013-04-21 公開日 2013-07-24 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Crystal Structure of 3-Hydroxybenzoate 6-Hydroxylase Uncovers Lipid-Assisted Flavoprotein Strategy for Regioselective Aromatic Hydroxylation J.Biol.Chem., 288, 2013
2RGJ	Crystal structure of flavin-containing monooxygenase PhzS 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Flavin-containing monooxygenase 著者 Ladner, J.E, Parsons, J.F, Greenhagen, B.T, Robinson, H. 登録日 2007-10-03 公開日 2008-05-20 最終更新日 2017-10-25 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal Structure of the Pyocyanin Biosynthetic Protein PhzS. Biochemistry, 47, 2008
5X68	Crystal Structure of Human KMO 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Kynurenine 3-monooxygenase 著者 Kim, H.T, Hwang, K.Y. 登録日 2017-02-21 公開日 2018-02-21 最終更新日 2018-05-02 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural Basis for Inhibitor-Induced Hydrogen Peroxide Production by Kynurenine 3-Monooxygenase Cell Chem Biol, 25, 2018
5X6P	Crystal structure of Pseudomonas fluorescens KMO 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Kynurenine 3-monooxygenase 著者 Kim, H.T, Hwang, K.Y. 登録日 2017-02-22 公開日 2018-02-21 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Structural Basis for Inhibitor-Induced Hydrogen Peroxide Production by Kynurenine 3-Monooxygenase Cell Chem Biol, 25, 2018
1CJ2	MUTANT GLN34ARG OF PARA-HYDROXYBENZOATE HYDROXYLASE 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, P-HYDROXYBENZOIC ACID, PROTEIN (P-HYDROXYBENZOATE HYDROXYLASE) 著者 Eppink, M.H.M, Overkamp, K.M, Schreuder, H.A, Van Berkel, W.J.H. 登録日 1999-04-21 公開日 1999-04-30 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Switch of coenzyme specificity of p-hydroxybenzoate hydroxylase. J.Mol.Biol., 292, 1999
5Y66	Crystal structure of Pseudomonas fluorescens Kynurenine 3-monooxygenase in complex with L-KYN and Ro61-8048 分子名称: (2S)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid, 3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Xiang, Y, Gao, J.J, Zhu, D.Y. 登録日 2017-08-10 公開日 2017-12-27 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 Biochemistry and structural studies of kynurenine 3-monooxygenase reveal allosteric inhibition by Ro 61-8048 FASEB J., 32, 2018
1CJ4	MUTANT Q34T OF PARA-HYDROXYBENZOATE HYDROXYLASE 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, P-HYDROXYBENZOIC ACID, PROTEIN (P-HYDROXYBENZOATE HYDROXYLASE) 著者 Eppink, M.H.M, Overkamp, K.M, Schreuder, H.A, Van Berkel, W.J.H. 登録日 1999-04-21 公開日 1999-04-30 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Switch of coenzyme specificity of p-hydroxybenzoate hydroxylase. J.Mol.Biol., 292, 1999
1D7L	STRUCTURE-FUNCTION CORRELATIONS OF THE REACTION OF REDUCED NICOTINAMIDE ANALOGS WITH P-HYDROXYBENZOATE HYDROXYLASE SUBSTITUTED WITH A SERIES OF 8-SUBSTITUTED FLAVINS 分子名称: 8-DEMETHYL-8-DIMETHYLAMINO-FLAVIN-ADENINE-DINUCLEOTIDE, P-HYDROXYBENZOATE HYDROXYLASE, P-HYDROXYBENZOIC ACID, ... 著者 Ortiz-Maldonado, M, Gatti, D, Ballou, D.P, Massey, V. 登録日 1999-10-18 公開日 2000-01-21 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure-function correlations of the reaction of reduced nicotinamide analogues with p-hydroxybenzoate hydroxylase substituted with a series of 8-substituted flavins. Biochemistry, 38, 1999
1CJ3	MUTANT TYR38GLU OF PARA-HYDROXYBENZOATE HYDROXYLASE 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, P-HYDROXYBENZOIC ACID, PROTEIN (P-HYDROXYBENZOATE HYDROXYLASE) 著者 Eppink, M.H.M, Overkamp, K.M, Schreuder, H.A, Van Berkel, W.J.H. 登録日 1999-04-21 公開日 1999-04-30 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Switch of coenzyme specificity of p-hydroxybenzoate hydroxylase. J.Mol.Biol., 292, 1999
5Y7A	Crystal structure of Pseudomonas fluorescens Kynurenine 3-monooxygenase in complex with L-KYN 分子名称: (2S)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, Kynurenine 3-monooxygenase 著者 Xiang, Y, Gao, J.J, Zhu, D.Y. 登録日 2017-08-16 公開日 2017-12-27 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.846 Å) 主引用文献 Biochemistry and structural studies of kynurenine 3-monooxygenase reveal allosteric inhibition by Ro 61-8048 FASEB J., 32, 2018
1DOD	THE MOBIL FLAVIN OF 4-OH BENZOATE HYDROXYLASE: MOTION OF A PROSTHETIC GROUP REGULATES CATALYSIS 分子名称: 2,4-DIHYDROXYBENZOIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, P-HYDROXYBENZOATE HYDROXYLASE 著者 Gatti, D.L, Palfey, B.A, Lah, M.S, Entsch, B, Massey, V, Ballou, D.P, Ludwig, M.L. 登録日 1994-09-06 公開日 1994-11-30 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The mobile flavin of 4-OH benzoate hydroxylase. Science, 266, 1994
1DOC	THE MOBIL FLAVIN OF 4-OH BENZOATE HYDROXYLASE: MOTION OF A PROSTHETIC GROUP REGULATES CATALYSIS 分子名称: BROMIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, P-HYDROXYBENZOATE HYDROXYLASE, ... 著者 Gatti, D.L, Palfey, B.A, Lah, M.S, Entsch, B, Massey, V, Ballou, D.P, Ludwig, M.L. 登録日 1994-09-06 公開日 1994-11-30 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The mobile flavin of 4-OH benzoate hydroxylase. Science, 266, 1994
5Y77	Crystal structure of Pseudomonas fluorescens Kynurenine 3-monooxygenase in complex with L-KYN (seMet derivative) 分子名称: (2S)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, Kynurenine 3-monooxygenase 著者 Xiang, Y, Gao, J.J, Zhu, D.Y. 登録日 2017-08-16 公開日 2017-12-27 最終更新日 2018-04-11 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Biochemistry and structural studies of kynurenine 3-monooxygenase reveal allosteric inhibition by Ro 61-8048 FASEB J., 32, 2018
1DOE	THE MOBIL FLAVIN OF 4-OH BENZOATE HYDROXYLASE: MOTION OF A PROSTHETIC GROUP REGULATES CATALYSIS 分子名称: 2,4-DIHYDROXYBENZOIC ACID, BROMIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Gatti, D.L, Palfey, B.A, Lah, M.S, Entsch, B, Massey, V, Ballou, D.P, Ludwig, M.L. 登録日 1994-09-06 公開日 1994-11-30 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The mobile flavin of 4-OH benzoate hydroxylase. Science, 266, 1994
1DOB	THE MOBIL FLAVIN OF 4-OH BENZOATE HYDROXYLASE: MOTION OF A PROSTHETIC GROUP REGULATES CATALYSIS 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, P-HYDROXYBENZOATE HYDROXYLASE, P-HYDROXYBENZOIC ACID 著者 Gatti, D.L, Palfey, B.A, Lah, M.S, Entsch, B, Massey, V, Ballou, D.P, Ludwig, M.L. 登録日 1994-09-06 公開日 1994-11-30 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The mobile flavin of 4-OH benzoate hydroxylase. Science, 266, 1994
6FOZ	The crystal structure of P.fluorescens Kynurenine 3-monooxygenase (KMO) in complex with competitive inhibitor No. 13 分子名称: 5-(3,4-dichlorophenyl)furan-2-carboxylic acid, FLAVIN-ADENINE DINUCLEOTIDE, Kynurenine 3-monooxygenase 著者 Levy, C.W, Leys, D. 登録日 2018-02-08 公開日 2019-08-21 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 A brain-permeable inhibitor of the neurodegenerative disease target kynurenine 3-monooxygenase prevents accumulation of neurotoxic metabolites. Commun Biol, 2, 2019
6FHO	Crystal structure of pqsL, a probable FAD-dependent monooxygenase from Pseudomonas aeruginosa - new refinement 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Probable FAD-dependent monooxygenase 著者 Belviso, B.D, Drees, S.L, Ernst, S, Jagmann, N, Hennecke, U, Fetzner, S. 登録日 2018-01-15 公開日 2018-04-25 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 PqsL uses reduced flavin to produce 2-hydroxylaminobenzoylacetate, a preferred PqsBC substrate in alkyl quinolone biosynthesis inPseudomonas aeruginosa. J. Biol. Chem., 293, 2018
6FOY	The crystal structure of P.fluorescens Kynurenine 3-monooxygenase (KMO) in complex with competitive inhibitor No. 9 分子名称: 5-[2,3-bis(chloranyl)phenyl]furan-2-carboxylic acid, CALCIUM ION, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Levy, C.W, Leys, D. 登録日 2018-02-08 公開日 2019-08-21 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 A brain-permeable inhibitor of the neurodegenerative disease target kynurenine 3-monooxygenase prevents accumulation of neurotoxic metabolites. Commun Biol, 2, 2019
6FP1	The crystal structure of P.fluorescens Kynurenine 3-monooxygenase (KMO) in complex with competitive inhibitor No. 1 分子名称: 2-(6-chloranyl-5,7-dimethyl-3-oxidanylidene-1,4-benzoxazin-4-yl)ethanoic acid, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Levy, C.W, Leys, D. 登録日 2018-02-08 公開日 2019-08-21 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 A brain-permeable inhibitor of the neurodegenerative disease target kynurenine 3-monooxygenase prevents accumulation of neurotoxic metabolites. Commun Biol, 2, 2019
6FPH	The crystal structure of P.fluorescens Kynurenine 3-monooxygenase (KMO) in complex with competitive inhibitor No. 1h 分子名称: 6-chloranyl-5,7-dimethyl-4-(1~{H}-1,2,3,4-tetrazol-5-ylmethyl)-1,4-benzoxazin-3-one, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Levy, C.W, Leys, D. 登録日 2018-02-09 公開日 2019-08-21 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 A brain-permeable inhibitor of the neurodegenerative disease target kynurenine 3-monooxygenase prevents accumulation of neurotoxic metabolites. Commun Biol, 2, 2019
5X6Q	Crystal structure of Pseudomonas fluorescens KMO in complex with Ro 61-8048 分子名称: 3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide, FLAVIN-ADENINE DINUCLEOTIDE, Kynurenine 3-monooxygenase 著者 Kim, H.T, Hwang, K.Y. 登録日 2017-02-23 公開日 2018-02-21 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.897 Å) 主引用文献 Structural Basis for Inhibitor-Induced Hydrogen Peroxide Production by Kynurenine 3-Monooxygenase Cell Chem Biol, 25, 2018
6FP0	The crystal structure of P.fluorescens Kynurenine 3-monooxygenase (KMO) in complex with competitive inhibitor No. 4 分子名称: (2~{R})-2-[[(2~{R})-5-chloranyl-1-methyl-2,3-dihydroindol-2-yl]carbonylamino]-2-cyclohexyl-ethanoic acid, DI(HYDROXYETHYL)ETHER, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Levy, C.W, Leys, D. 登録日 2018-02-08 公開日 2019-08-21 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 A brain-permeable inhibitor of the neurodegenerative disease target kynurenine 3-monooxygenase prevents accumulation of neurotoxic metabolites. Commun Biol, 2, 2019
6FOX	The crystal structure of P.fluorescens Kynurenine 3-monooxygenase (KMO) in complex with kynurenine 分子名称: (2S)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid, CALCIUM ION, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Levy, C.W, Leys, D. 登録日 2018-02-08 公開日 2019-08-21 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 A brain-permeable inhibitor of the neurodegenerative disease target kynurenine 3-monooxygenase prevents accumulation of neurotoxic metabolites. Commun Biol, 2, 2019
5X6R	Crystal structure of Saccharomyces cerevisiae KMO in complex with Ro 61-8048 分子名称: 3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide, FLAVIN-ADENINE DINUCLEOTIDE, Kynurenine 3-monooxygenase 著者 Kim, H.T, Hwang, K.Y. 登録日 2017-02-23 公開日 2018-02-21 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.911 Å) 主引用文献 Structural Basis for Inhibitor-Induced Hydrogen Peroxide Production by Kynurenine 3-Monooxygenase Cell Chem Biol, 25, 2018
1PHH	CRYSTAL STRUCTURE OF P-HYDROXYBENZOATE HYDROXYLASE COMPLEXED WITH ITS REACTION PRODUCT 3,4-DIHYDROXYBENZOATE 分子名称: 3,4-DIHYDROXYBENZOIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, P-HYDROXYBENZOATE HYDROXYLASE 著者 Schreuder, H.A, Drenth, J. 登録日 1987-11-04 公開日 1988-04-16 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of p-hydroxybenzoate hydroxylase complexed with its reaction product 3,4-dihydroxybenzoate. J.Mol.Biol., 199, 1988

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