5Y77

Crystal structure of Pseudomonas fluorescens Kynurenine 3-monooxygenase in complex with L-KYN (seMet derivative)

Summary for 5Y77

• Entry DOI: 10.2210/pdb5y77/pdb
• Related: 5Y66
• Descriptor: Kynurenine 3-monooxygenase, FLAVIN-ADENINE DINUCLEOTIDE, (2S)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid, ... (4 entities in total)
• Functional Keywords: kmo, l-kyn, enzyme, 3-hydroxy-l-kynurenine (l-3ohkyn), oxidoreductase
• Biological source: Pseudomonas fluorescens
• Total number of polymer chains: 2
• Total formula weight: 107526.72

Authors

Xiang, Y.,Gao, J.J.,Zhu, D.Y. (deposition date: 2017-08-16, release date: 2017-12-27, Last modification date: 2018-04-11)

• Primary citation: Gao, J.,Yao, L.,Xia, T.,Liao, X.,Zhu, D.,Xiang, Y.; Biochemistry and structural studies of kynurenine 3-monooxygenase reveal allosteric inhibition by Ro 61-8048; FASEB J., 32:2036-2045, 2018; PubMed: 29208702; DOI: 10.1096/fj.201700397RR

Experimental method

X-RAY DIFFRACTION (1.6 Å)