5Y66
Crystal structure of Pseudomonas fluorescens Kynurenine 3-monooxygenase in complex with L-KYN and Ro61-8048
Summary for 5Y66
Entry DOI | 10.2210/pdb5y66/pdb |
Descriptor | Kynurenine 3-monooxygenase, FLAVIN-ADENINE DINUCLEOTIDE, 3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide, ... (5 entities in total) |
Functional Keywords | kmo, inhibitor, l-kyn, ro 61-8048, oxidoreductase |
Biological source | Pseudomonas fluorescens |
Total number of polymer chains | 1 |
Total formula weight | 53528.28 |
Authors | |
Primary citation | Gao, J.,Yao, L.,Xia, T.,Liao, X.,Zhu, D.,Xiang, Y. Biochemistry and structural studies of kynurenine 3-monooxygenase reveal allosteric inhibition by Ro 61-8048 FASEB J., 32:2036-2045, 2018 Cited by PubMed: 29208702DOI: 10.1096/fj.201700397RR PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.34 Å) |
Structure validation
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