5Y66

Crystal structure of Pseudomonas fluorescens Kynurenine 3-monooxygenase in complex with L-KYN and Ro61-8048

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Kynurenine 3-monooxygenase	polymer	473	52113.1	1	UniProt (Q84HF5) Pfam (PF01494) In PDB	Pseudomonas fluorescens	PfKMO,Kynurenine 3-hydroxylase
2	A	FLAVIN-ADENINE DINUCLEOTIDE	non-polymer		785.5	1	Chemie (FAD)
3	A	3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide	non-polymer		421.4	1	Chemie (7ZR)
4	A	(2S)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid	non-polymer		208.2	1	Chemie (KYN)
5		water	water		18.0	108	Chemie (HOH)

Sequence modifications

A: 2 - 461 (UniProt: Q84HF5)

PDB	External Database	Details
Met 0	-	expression tag
Gly 1	-	expression tag
Ala 462	-	expression tag
Ala 463	-	expression tag
Ala 464	-	expression tag
Leu 465	-	expression tag
Glu 466	-	expression tag
His 467	-	expression tag
His 468	-	expression tag
His 469	-	expression tag
His 470	-	expression tag
His 471	-	expression tag
His 472	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	52113.1
Non-Polymers*	Number of molecules	3
	Total formula weight	1415.2
All*	Total formula weight	53528.3

*Water molecules are not included.