PDB: 198 件ウェブページステータス検索Chemie searchBIRD

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3GPM	Structure of the trimeric form of the E113G PCNA mutant protein 分子名称: Proliferating cell nuclear antigen 著者 Freudenthal, B.D, Gakhar, L, Ramaswamy, S, Washington, M.T. 登録日 2009-03-23 公開日 2009-06-16 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.8 Å) 主引用文献 A charged residue at the subunit interface of PCNA promotes trimer formation by destabilizing alternate subunit interactions. Acta Crystallogr.,Sect.D, 65, 2009
3HI8	Crystal structure of proliferating cell nuclear antigen (PCNA) from Haloferax volcanii 分子名称: Proliferating cell nuclear antigen PcnA 著者 Morgunova, E, Gray, F.C, MacNeill, S.A, Ladenstein, R. 登録日 2009-05-19 公開日 2009-09-29 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.202 Å) 主引用文献 Structural insights into the adaptation of proliferating cell nuclear antigen (PCNA) from Haloferax volcanii to a high-salt environment. Acta Crystallogr.,Sect.D, 65, 2009
3FDS	Structural insight into recruitment of translesion DNA polymerase Dpo4 to sliding clamp PCNA 分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, DNA polymerase IV, ... 著者 Ling, H. 登録日 2008-11-26 公開日 2009-01-20 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structural insight into recruitment of translesion DNA polymerase Dpo4 to sliding clamp PCNA Mol.Microbiol., 71, 2009
3VKX	Structure of PCNA 分子名称: 3,5,3'TRIIODOTHYRONINE, CHLORIDE ION, Proliferating cell nuclear antigen, ... 著者 Hashimoto, H, Hishiki, A, Shimizu, T, Sato, M, Punchihewa, C, Connelly, M, Actis, M, Waddell, B, Pagala, V, Fujii, N. 登録日 2011-11-26 公開日 2012-03-14 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Identification of small molecule proliferating cell nuclear antigen (PCNA) inhibitor that disrupts interactions with PIP-box proteins and inhibits DNA replication J.Biol.Chem., 287, 2012
1RXZ	C-terminal region of A. fulgidus FEN-1 complexed with A. fulgidus PCNA 分子名称: DNA polymerase sliding clamp, Flap structure-specific endonuclease 著者 Chapados, B.R, Hosfield, D.J, Han, S, Qiu, J, Yelent, B, Shen, B, Tainer, J.A. 登録日 2003-12-18 公開日 2004-01-27 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural Basis for FEN-1 Substrate Specificity and PCNA-Mediated Activation in DNA Replication and Repair Cell(Cambridge,Mass.), 116, 2004
3IFV	Crystal structure of the Haloferax volcanii proliferating cell nuclear antigen 分子名称: PCNA, SODIUM ION 著者 Winter, J.A, Christofi, P, Morroll, S, Bunting, K.A. 登録日 2009-07-26 公開日 2009-09-01 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The crystal structure of Haloferax volcanii proliferating cell nuclear antigen reveals unique surface charge characteristics due to halophilic adaptation Bmc Struct.Biol., 9, 2009
1RWZ	Crystal Structure of Proliferating Cell Nuclear Antigen (PCNA) from A. fulgidus 分子名称: DNA polymerase sliding clamp 著者 Chapados, B.R, Hosfield, D.J, Han, S, Qiu, J, Yelent, B, Shen, B, Tainer, J.A. 登録日 2003-12-17 公開日 2004-01-27 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural Basis for FEN-1 Substrate Specificity and PCNA-Mediated Activation in DNA Replication and Repair Cell(Cambridge,Mass.), 116, 2004
3GPN	Structure of the non-trimeric form of the E113G PCNA mutant protein 分子名称: Proliferating cell nuclear antigen 著者 Freudenthal, B.D, Gakhar, L, Ramaswamy, S, Washington, M.T. 登録日 2009-03-23 公開日 2009-06-16 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 A charged residue at the subunit interface of PCNA promotes trimer formation by destabilizing alternate subunit interactions. Acta Crystallogr.,Sect.D, 65, 2009
1RXM	C-terminal region of FEN-1 bound to A. fulgidus PCNA 分子名称: DNA polymerase sliding clamp, consensus FEN-1 peptide 著者 Chapados, B.R, Hosfield, D.J, Han, S, Qiu, J, Yelent, B, Shen, B, Tainer, J.A. 登録日 2003-12-18 公開日 2004-01-27 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural Basis for FEN-1 Substrate Specificity and PCNA-Mediated Activation in DNA Replication and Repair Cell(Cambridge,Mass.), 116, 2004
3WGW	Structure of PCNA bound to a small molecule inhibitor 分子名称: 4-{4-[(2S)-2-amino-3-hydroxypropyl]-2,6-diiodophenoxy}phenol, Proliferating cell nuclear antigen, SULFATE ION 著者 Hashimoto, H. 登録日 2013-08-12 公開日 2014-02-05 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 A small molecule inhibitor of monoubiquitinated Proliferating Cell Nuclear Antigen (PCNA) inhibits repair of interstrand DNA cross-link, enhances DNA double strand break, and sensitizes cancer cells to cisplatin. J.Biol.Chem., 289, 2014
1UD9	Crystal Structure of Proliferating Cell Nuclear Antigen (PCNA) Homolog From Sulfolobus tokodaii 分子名称: DNA polymerase sliding clamp A, ZINC ION 著者 Tanabe, E, Yasutake, Y, Tanaka, Y, Yao, M, Tsumoto, K, Kumagai, I, Tanaka, I. 登録日 2003-04-28 公開日 2004-06-15 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 Crystal Structure of Proliferating Cell Nuclear Antigen (PCNA) Homolog From Sulfolobus tokodaii To be published
3L0X	Structure of split yeast PCNA 分子名称: Proliferating cell nuclear antigen 著者 Freudenthal, B.D, Gakhar, L, Ramaswamy, S, Washington, M.T. 登録日 2009-12-10 公開日 2010-03-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structure of monoubiquitinated PCNA and implications for translesion synthesis and DNA polymerase exchange. Nat.Struct.Mol.Biol., 17, 2010
1U7B	Crystal structure of hPCNA bound to residues 331-350 of the flap endonuclease-1 (FEN1) 分子名称: Proliferating cell nuclear antigen, SRQGSTQGRLDDFFKVTGSL peptide of Flap endonuclease-1 著者 Bruning, J.B, Shamoo, Y. 登録日 2004-08-03 公開日 2004-12-14 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Structural and Thermodynamic Analysis of Human PCNA with Peptides Derived from DNA Polymerase-delta p66 Subunit and Flap Endonuclease-1. Structure, 12, 2004
5AUJ	Pyrococcus furiosus proliferating cell nuclear antigen (PCNA) SeMet derivative 分子名称: DNA polymerase sliding clamp 著者 Watanabe, Y, Oyama, T. 登録日 2015-04-21 公開日 2016-04-27 最終更新日 2020-02-19 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Pyrococcus furiosus proliferating cell nuclear antigen (PCNA) SeMet derivative To Be Published
1W60	NATIVE HUMAN PCNA 分子名称: PROLIFERATING CELL NUCLEAR ANTIGEN 著者 Kontopidis, G, Wu, S, Zheleva, D, Taylor, P, Mcinnes, C, Lane, D, Fischer, P, Walkinshaw, M. 登録日 2004-08-11 公開日 2005-01-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Structural and Biochemical Studies of Human Proliferating Cell Nuclear Antigen Complexes Provide a Rationale for Cyclin Association and Inhibitor Design Proc.Natl.Acad.Sci.USA, 102, 2005
1VYJ	Structural and biochemical studies of human PCNA complexes provide the basis for association with CDK/cyclin and rationale for inhibitor design 分子名称: PROLIFERATING CELL NUCLEAR ANTIGEN, SMALL PEPTIDE SAVLQKKITDYFHPKK 著者 Kontopidis, G, Wu, S, Zheleva, D, Taylor, P, Mcinnes, C, Lane, D, Fischer, P, Walkinshaw, M.D. 登録日 2004-04-30 公開日 2005-01-13 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural and Biochemical Studies of Human Proliferating Cell Nuclear Antigen Complexes Provide a Rationale for Cyclin Association and Inhibitor Design Proc.Natl.Acad.Sci.USA, 102, 2005
5CFK	Crystal structure of Proliferating Cell Nuclear Antigen from Leishmania donovani at 3.2 A resolution 分子名称: Proliferating cell nuclear antigen,Proliferating cell nuclear antigen 著者 Shukla, P.K, Yadav, S.P, Sharma, P, Kaur, P, Sharma, S, Singh, T.P. 登録日 2015-07-08 公開日 2015-10-07 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Crystal structure of Proliferating Cell Nuclear Antigen from Leishmania donovani at 3.2 A resolution To Be Published
3LX2	Crystal Structure analysis of PCNA from Thermococcus kodakaraensis tk0582 分子名称: DNA polymerase sliding clamp 2, SULFATE ION 著者 Ladner, J.E, Kelman, Z, Pan, M. 登録日 2010-02-24 公開日 2011-01-26 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structures of two active proliferating cell nuclear antigens (PCNAs) encoded by Thermococcus kodakaraensis. Proc.Natl.Acad.Sci.USA, 108, 2011
1VYM	NATIVE HUMAN PCNA 分子名称: PROLIFERATING CELL NUCLEAR ANTIGEN 著者 Kontopidis, G, Wu, S, Zheleva, D, Taylor, P, Mcinnes, C, Lane, D, Fischer, P, Walkinshaw, M. 登録日 2004-05-03 公開日 2005-01-13 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural and Biochemical Studies of Human Proliferating Cell Nuclear Antigen Complexes Provide a Rationale for Cyclin Association and Inhibitor Design Proc.Natl.Acad.Sci.USA, 102, 2005
3LX1	Crystal Structure analysis of PCNA1 from Thermococcus kodakaraensis tk0535 分子名称: DNA polymerase sliding clamp 1, SULFATE ION 著者 Ladner, J.E, Kelman, Z, Pan, M. 登録日 2010-02-24 公開日 2011-01-26 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structures of two active proliferating cell nuclear antigens (PCNAs) encoded by Thermococcus kodakaraensis. Proc.Natl.Acad.Sci.USA, 108, 2011
5DA7	monomeric PCNA bound to a small protein inhibitor 分子名称: DNA polymerase sliding clamp 1, Proliferating cell nuclear antigen, SULFATE ION, ... 著者 Ladner, J.E, Altieri, A.S, Kelman, Z. 登録日 2015-08-19 公開日 2016-05-11 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.802 Å) 主引用文献 A small protein inhibits proliferating cell nuclear antigen by breaking the DNA clamp. Nucleic Acids Res., 44, 2016
3K4X	Eukaryotic Sliding Clamp PCNA Bound to DNA 分子名称: DNA (5'-D(*CP*CP*CP*AP*TP*CP*GP*TP*AP*T)-3'), DNA (5'-D(*TP*TP*TP*TP*AP*TP*AP*CP*GP*AP*TP*GP*GP*G)-3'), Proliferating cell nuclear antigen 著者 McNally, R, Kuriyan, J. 登録日 2009-10-06 公開日 2010-02-16 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.98 Å) 主引用文献 Analysis of the role of PCNA-DNA contacts during clamp loading. Bmc Struct.Biol., 10, 2010
3JA9	Structure of native human PCNA 分子名称: Proliferating cell nuclear antigen 著者 Lau, W.C.Y, Li, Y, Zhang, Q, Huen, M.S.Y. 登録日 2015-05-19 公開日 2015-12-09 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (22 Å) 主引用文献 Molecular architecture of the Ub-PCNA/Pol eta complex bound to DNA Sci Rep, 5, 2015
5DAI	Proliferating cell nuclear antigen homolog 1 bound to FEN-1 peptide 分子名称: C-terminus of FEN-1 protein, DNA polymerase sliding clamp 1, SULFATE ION 著者 Ladner, J.E, Altieri, A.S, Kelman, Z. 登録日 2015-08-20 公開日 2016-05-11 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 A small protein inhibits proliferating cell nuclear antigen by breaking the DNA clamp. Nucleic Acids Res., 44, 2016
6QC0	PCNA complex with Cdt2 C-terminal PIP-box peptide 分子名称: Denticleless protein homolog, Proliferating cell nuclear antigen 著者 Perrakis, A.P, von Castelmur, E. 登録日 2018-12-25 公開日 2019-01-23 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Direct binding of Cdt2 to PCNA is important for targeting the CRL4Cdt2E3 ligase activity to Cdt1. Life Sci Alliance, 1, 2018

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