PDB: 253 件ウェブページステータス検索Chemie searchBIRD

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3ZFC	Crystal Structure of the Kif4 Motor Domain Complexed With Mg-AMPPNP 分子名称: CHROMOSOME-ASSOCIATED KINESIN KIF4, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER 著者 Chang, Q, Nitta, R, Inoue, S, Hirokawa, N. 登録日 2012-12-11 公開日 2013-03-20 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural Basis for the ATP-Induced Isomerization of Kinesin. J.Mol.Biol., 425, 2013
3ZFD	Crystal Structure of the Kif4 Motor Domain Complexed With Mg-AMPPNP 分子名称: CHROMOSOME-ASSOCIATED KINESIN KIF4, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER 著者 Chang, Q, Nitta, R, Inoue, S, Hirokawa, N. 登録日 2012-12-11 公開日 2013-03-20 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.71 Å) 主引用文献 Structural Basis for the ATP-Induced Isomerization of Kinesin. J.Mol.Biol., 425, 2013
4BBG	Crystal structure of human kinesin Eg5 in complex with 3-(((2-Aminoethyl)sulfanyl)(3-ethylphenyl) phenylmethyl)phenol 分子名称: 3-[(R)-2-azanylethylsulfanyl-(3-ethylphenyl)-phenyl-methyl]phenol, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ... 著者 Kaan, H.Y.K, Kozielski, F. 登録日 2012-09-22 公開日 2013-05-15 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Optimized S-Trityl-L-Cysteine-Based Inhibitors of Kinesin Spindle Protein with Potent in Vivo Antitumor Activity in Lung Cancer Xenograft Models. J.Med.Chem., 56, 2013
4AS7	Eg5 complex 1 分子名称: ADENOSINE-5'-DIPHOSPHATE, CADMIUM ION, CHLORIDE ION, ... 著者 Talapatra, S.K, Kozielski, F. 登録日 2012-04-29 公開日 2013-05-15 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 The Mitotic Kinesin Eg5 Overcomes Inhibition to the Phase I/II Clinical Candidate Sb743921 by an Allosteric Resistance Mechanism. J.Med.Chem., 56, 2013
4HNA	Kinesin motor domain in the ADP-MG-ALFX state in complex with tubulin and a DARPIN 分子名称: ADENOSINE-5'-DIPHOSPHATE, DESIGNED ANKYRIN REPEAT PROTEIN (DARPIN) D2, GUANOSINE-5'-DIPHOSPHATE, ... 著者 Gigant, B, Knossow, M. 登録日 2012-10-19 公開日 2013-06-12 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.19 Å) 主引用文献 Structure of a kinesin-tubulin complex and implications for kinesin motility. Nat.Struct.Mol.Biol., 20, 2013
4FRZ	Arabidopsis KCBP motor domain dimerized via regulatory domain 分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, IMIDAZOLE, ... 著者 Vinogradova, M. 登録日 2012-06-26 公開日 2013-07-10 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Plant Kinesin-Like Calmodulin Binding Protein Employs Its Regulatory Domain for Dimerization. Plos One, 8, 2013
4B7B	Eg5-3 分子名称: ADENOSINE-5'-DIPHOSPHATE, CADMIUM ION, CALCIUM ION, ... 著者 Talapatra, S.K, Kozielski, F. 登録日 2012-08-17 公開日 2013-07-31 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The Mitotic Kinesin Eg5 Overcomes Inhibition to the Phase I/II Clinical Candidate Sb743921 by an Allosteric Resistance Mechanism. J.Med.Chem., 56, 2013
4BXN	Eg5(WT) complex 分子名称: ADENOSINE-5'-DIPHOSPHATE, CADMIUM ION, CHLORIDE ION, ... 著者 Talapatra, S.K, Anthony, N.G, Mackay, S.P, Kozielski, F. 登録日 2013-07-15 公開日 2013-07-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.793 Å) 主引用文献 The Mitotic Kinesin Eg5 Overcomes Inhibition to the Phase I/II Clinical Candidate Sb743921 by an Allosteric Resistance Mechanism. J.Med.Chem., 56, 2013
4BN2	The crystal structure of kinesin-like protein KIF15 分子名称: ADENOSINE-5'-DIPHOSPHATE, KINESIN-LIKE PROTEIN KIF15, MAGNESIUM ION 著者 Klejnot, M, Falnikar, A, Ulaganathan, V, Cross, R, Baas, P, Kozielski, F. 登録日 2013-05-13 公開日 2014-01-15 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.695 Å) 主引用文献 The Crystal Structure and Biochemical Characterization of Kif15: A Bifunctional Molecular Motor Involved in Bipolar Spindle Formation and Neuronal Development Acta Crystallogr.,Sect.D, 70, 2014
4CK6	Pseudo-atomic model of microtubule-bound human kinesin-5 motor domain in the ADP.AlFx state, based on cryo-electron microscopy experiment. 分子名称: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, ... 著者 Goulet, A, Major, J, Jun, Y, Gross, S, Rosenfeld, S, Moores, C. 登録日 2013-12-30 公開日 2014-02-05 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (9.2 Å) 主引用文献 Comprehensive Structural Model of the Mechanochemical Cycle of a Mitotic Motor Highlights Molecular Adaptations in the Kinesin Family. Proc.Natl.Acad.Sci.USA, 111, 2014
4CK7	Pseudo-atomic model of microtubule-bound human kinesin-5 motor domain in presence of adp.alfx (NECK-LINKER IN ITS DISCONNECTED CONFORMATION, based on cryo-electron microscopy experiment 分子名称: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, ... 著者 Goulet, A, Major, J, Jun, Y, Gross, S, Rosenfeld, S, Moores, C. 登録日 2013-12-30 公開日 2014-02-05 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (9.2 Å) 主引用文献 Comprehensive Structural Model of the Mechanochemical Cycle of a Mitotic Motor Highlights Molecular Adaptations in the Kinesin Family. Proc.Natl.Acad.Sci.USA, 111, 2014
4CK5	Pseudo-atomic model of microtubule-bound human kinesin-5 motor domain in the ADP state, based on cryo-electron microscopy experiment. 分子名称: ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Goulet, A, Major, J, Jun, Y, Gross, S, Rosenfeld, S, Moores, C. 登録日 2013-12-30 公開日 2014-02-05 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (10 Å) 主引用文献 Comprehensive Structural Model of the Mechanochemical Cycle of a Mitotic Motor Highlights Molecular Adaptations in the Kinesin Family. Proc.Natl.Acad.Sci.USA, 111, 2014
4OZQ	Crystal structure of the mouse Kif14 motor domain 分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, Chimera of Maltose-binding periplasmic protein and Kinesin family member 14 protein 著者 Arora, K, Talje, L, Asenjo, A.B, Andersen, P, Atchia, K, Joshi, M, Sosa, H, Kwok, B.H, Allingham, J.S. 登録日 2014-02-18 公開日 2014-07-09 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.71 Å) 主引用文献 KIF14 binds tightly to microtubules and adopts a rigor-like conformation. J.Mol.Biol., 426, 2014
4UXP	Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins 分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, KINESIN-3 MOTOR DOMAIN, ... 著者 Atherton, J, Farabella, I, Yu, I.M, Rosenfeld, S.S, Houdusse, A, Topf, M, Moores, C. 登録日 2014-08-27 公開日 2014-09-24 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (6.3 Å) 主引用文献 Conserved Mechanisms of Microtubule-Stimulated Adp Release, ATP Binding, and Force Generation in Transport Kinesins. Elife, 3, 2014
4UXY	Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins 分子名称: ALPHA TUBULIN, BETA TUBULIN, GUANOSINE-5'-DIPHOSPHATE, ... 著者 Atherton, J, Farabella, I, Yu, I.M, Rosenfeld, S.S, Houdusse, A, Topf, M, Moores, C. 登録日 2014-08-27 公開日 2014-09-24 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (6.5 Å) 主引用文献 Conserved Mechanisms of Microtubule-Stimulated Adp Release, ATP Binding, and Force Generation in Transport Kinesins. Elife, 3, 2014
4UXS	Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins 分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, KINESIN-3 MOTOR DOMAIN, ... 著者 Atherton, J, Farabella, I, Yu, I.M, Rosenfeld, S.S, Houdusse, A, Topf, M, Moores, C. 登録日 2014-08-27 公開日 2014-09-24 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (7 Å) 主引用文献 Conserved Mechanisms of Microtubule-Stimulated Adp Release, ATP Binding, and Force Generation in Transport Kinesins. Elife, 3, 2014
4UXR	Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins 分子名称: ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Atherton, J, Farabella, I, Yu, I.M, Rosenfeld, S.S, Houdusse, A, Topf, M, Moores, C. 登録日 2014-08-27 公開日 2014-09-24 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (7 Å) 主引用文献 Conserved Mechanisms of Microtubule-Stimulated Adp Release, ATP Binding, and Force Generation in Transport Kinesins. Elife, 3, 2014
4UY0	Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins 分子名称: ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Atherton, J, Farabella, I, Yu, I.M, Rosenfeld, S.S, Houdusse, A, Topf, M, Moores, C. 登録日 2014-08-27 公開日 2014-09-24 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (7.7 Å) 主引用文献 Conserved Mechanisms of Microtubule-Stimulated Adp Release, ATP Binding, and Force Generation in Transport Kinesins. Elife, 3, 2014
4UXO	Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins 分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, KINESIN-3 MOTOR DOMAIN, ... 著者 Atherton, J, Farabella, I, Yu, I.M, Rosenfeld, S.S, Houdusse, A, Topf, M, Moores, C. 登録日 2014-08-27 公開日 2014-09-24 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (6.3 Å) 主引用文献 Conserved Mechanisms of Microtubule-Stimulated Adp Release, ATP Binding, and Force Generation in Transport Kinesins. Elife, 3, 2014
4UXT	Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins 分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, KINESIN HEAVY CHAIN ISOFORM 5A, ... 著者 Atherton, J, Farabella, I, Yu, I.M, Rosenfeld, S.S, Houdusse, A, Topf, M, Moores, C. 登録日 2014-08-27 公開日 2014-09-24 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (7.4 Å) 主引用文献 Conserved Mechanisms of Microtubule-Stimulated Adp Release, ATP Binding, and Force Generation in Transport Kinesins. Elife, 3, 2014
4LNU	Nucleotide-free kinesin motor domain in complex with tubulin and a DARPin 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Designed ankyrin repeat protein (DARPIN) D1, GLYCEROL, ... 著者 Cao, L, Gigant, B, Knossow, M. 登録日 2013-07-12 公開日 2014-12-03 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.19 Å) 主引用文献 The structure of apo-kinesin bound to tubulin links the nucleotide cycle to movement Nat Commun, 5, 2014
3J8X	High-resolution structure of no-nucleotide kinesin on microtubules 分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-1 heavy chain, ... 著者 Shang, Z, Zhou, K, Xu, C, Csencsits, R, Cochran, J.C, Sindelar, C.V. 登録日 2014-11-20 公開日 2014-12-10 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (5 Å) 主引用文献 High-resolution structures of kinesin on microtubules provide a basis for nucleotide-gated force-generation. Elife, 3, 2014
3J8Y	High-resolution structure of ATP analog-bound kinesin on microtubules 分子名称: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Shang, Z, Zhou, K, Xu, C, Csencsits, R, Cochran, J.C, Sindelar, C.V. 登録日 2014-11-20 公開日 2014-12-10 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (5 Å) 主引用文献 High-resolution structures of kinesin on microtubules provide a basis for nucleotide-gated force-generation. Elife, 3, 2014
3WPN	Kinesin spindle protein Eg5 in complex with ATP-competitive inhibitor PVZB1194 分子名称: 3'-fluoro-4'-(trifluoromethyl)biphenyl-4-sulfonamide, Kinesin-like protein KIF11 著者 Yokoyama, H, Katoh, S, Fujii, S. 登録日 2014-01-14 公開日 2015-01-21 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural basis of new allosteric inhibition in Kinesin spindle protein eg5 Acs Chem.Biol., 10, 2015
3X2T	Crystal Structure of the KIF5C Motor Domain With ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, Kinesin heavy chain isoform 5C 著者 Inoue, S, Nitta, R, Hirokawa, N. 登録日 2015-01-02 公開日 2015-04-01 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 X-ray and Cryo-EM structures reveal mutual conformational changes of Kinesin and GTP-state microtubules upon binding Embo J., 34, 2015

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