PDB: 194 件ウェブページステータス検索Chemie searchBIRD

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3F48	Crystal structure of LeuT bound to L-alanine and sodium 分子名称: ALANINE, SODIUM ION, Transporter, ... 著者 Singh, S.K, Piscitelli, C.L, Yamashita, A, Gouaux, E. 登録日 2008-10-31 公開日 2008-12-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 A competitive inhibitor traps LeuT in an open-to-out conformation. Science, 322, 2008
3GJD	Crystal Structure of LeuT with bound OG 分子名称: CHLORIDE ION, LEUCINE, SODIUM ION, ... 著者 Winther, A.M.L, Quick, M, Javitch, J.A, Nissen, P. 登録日 2009-03-08 公開日 2009-04-28 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Binding of an octylglucoside detergent molecule in the second substrate (S2) site of LeuT establishes an inhibitor-bound conformation Proc.Natl.Acad.Sci.USA, 106, 2009
3F3C	Crystal structure of LeuT bound to 4-Fluoro-L-Phenylalanine and sodium 分子名称: 4-FLUORO-L-PHENYLALANINE, SODIUM ION, Transporter, ... 著者 Singh, S.K, Piscitelli, C.L, Yamashita, A, Gouaux, E. 登録日 2008-10-30 公開日 2008-12-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 A competitive inhibitor traps LeuT in an open-to-out conformation. Science, 322, 2008
3GWU	Leucine transporter LeuT in complex with sertraline 分子名称: (1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine, LEUCINE, SODIUM ION, ... 著者 Zhou, Z, Zhen, J, Karpowich, N.K, Law, C.J, Reith, M.E.A, Wang, D.N. 登録日 2009-04-01 公開日 2009-05-12 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Antidepressant specificity of serotonin transporter suggested by three LeuT-SSRI structures. Nat.Struct.Mol.Biol., 16, 2009
3GJC	Crystal Structure of the E290S mutant of LeuT with bound OG 分子名称: LEUCINE, SODIUM ION, Transporter, ... 著者 Winther, A.M.L, Quick, M, Javitch, J.A, Nissen, P. 登録日 2009-03-08 公開日 2009-04-28 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Binding of an octylglucoside detergent molecule in the second substrate (S2) site of LeuT establishes an inhibitor-bound conformation Proc.Natl.Acad.Sci.USA, 106, 2009
3GWV	Leucine transporter LeuT in complex with R-fluoxetine 分子名称: (3R)-N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine, LEUCINE, SODIUM ION, ... 著者 Zhou, Z, Zhen, J, Karpowich, N.K, Law, C.J, Reith, M.E.A, Wang, D.N. 登録日 2009-04-01 公開日 2009-05-12 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Antidepressant specificity of serotonin transporter suggested by three LeuT-SSRI structures. Nat.Struct.Mol.Biol., 16, 2009
3GWW	Leucine transporter LeuT in complex with S-fluoxetine 分子名称: (3S)-N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine, LEUCINE, SODIUM ION, ... 著者 Zhou, Z, Zhen, J, Karpowich, N.K, Law, C.J, Reith, M.E.A, Wang, D.N. 登録日 2009-04-01 公開日 2009-05-12 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.46 Å) 主引用文献 Antidepressant specificity of serotonin transporter suggested by three LeuT-SSRI structures. Nat.Struct.Mol.Biol., 16, 2009
3F3A	Crystal Structure of LeuT bound to L-Tryptophan and Sodium 分子名称: SODIUM ION, TETRADECANE, TRYPTOPHAN, ... 著者 Singh, S.K, Piscitelli, C.L, Yamashita, A, Gouaux, E. 登録日 2008-10-30 公開日 2008-12-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 A competitive inhibitor traps LeuT in an open-to-out conformation. Science, 322, 2008
4XNU	X-ray structure of Drosophila dopamine transporter in complex with nisoxetine 分子名称: CHLORIDE ION, CHOLESTEROL, Integral membrane protein-dopamine transporter, ... 著者 Aravind, P, Wang, K, Gouaux, E. 登録日 2015-01-16 公開日 2015-05-13 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.98 Å) 主引用文献 X-ray structures of Drosophila dopamine transporter in complex with nisoxetine and reboxetine. Nat.Struct.Mol.Biol., 22, 2015
4XPF	X-ray structure of Drosophila dopamine transporter with subsiteB mutations (D121G/S426M) bound to RTI-55 分子名称: 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, ANTIBODY FRAGMENT HEAVY CHAIN-PROTEIN, 9D5-HEAVY CHAIN, ... 著者 Penmatsa, A, Wang, K.H, Gouaux, E. 登録日 2015-01-16 公開日 2015-05-06 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.273 Å) 主引用文献 Neurotransmitter and psychostimulant recognition by the dopamine transporter. Nature, 521, 2015
4XP1	X-ray structure of Drosophila dopamine transporter bound to neurotransmitter dopamine 分子名称: 1,2-ETHANEDIOL, 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Gouaux, E, Penmatsa, A, Wang, K. 登録日 2015-01-16 公開日 2015-05-06 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.89 Å) 主引用文献 Neurotransmitter and psychostimulant recognition by the dopamine transporter. Nature, 521, 2015
4XPG	X-ray structure of Drosophila dopamine transporter with subsiteB mutations (D121G/S426M) bound to beta-CFT or Win35428 分子名称: CHLORIDE ION, CHOLESTEROL, Dopamine transporter, ... 著者 Penmatsa, A, Wang, K.H, Gouaux, E. 登録日 2015-01-16 公開日 2015-05-06 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (3.21 Å) 主引用文献 Neurotransmitter and psychostimulant recognition by the dopamine transporter. Nature, 521, 2015
4XP5	X-ray structure of Drosophila dopamine transporter bound to cocaine analogue-RTI55 分子名称: 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, Antibody fragment heavy chain-protein, 9D5-heavy chain, ... 著者 Gouaux, E, Penmatsa, A, Wang, K. 登録日 2015-01-16 公開日 2015-05-06 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Neurotransmitter and psychostimulant recognition by the dopamine transporter. Nature, 521, 2015
4XPB	X-ray structure of Drosophila dopamine transporter with subsiteB mutations (D121G/S426M) bound to cocaine 分子名称: Antibody fragment heavy chain-protein, 9D5-heavy chain, Antibody fragment light chain-protein, ... 著者 Aravind, P, Wang, K, Gouaux, E. 登録日 2015-01-16 公開日 2015-05-13 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (3.05 Å) 主引用文献 Neurotransmitter and psychostimulant recognition by the dopamine transporter. Nature, 521, 2015
4XPT	X-ray structure of Drosophila dopamine transporter with subsiteB mutations D121G/S426M and EL2 deletion of 162-201 in complex with substrate analogue 3,4 dichlorophen ethylamine 分子名称: 2-(3,4-dichlorophenyl)ethanamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... 著者 Aravind, P, Wang, K, Gouaux, E. 登録日 2015-01-17 公開日 2015-05-06 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (3.36 Å) 主引用文献 Neurotransmitter and psychostimulant recognition by the dopamine transporter. Nature, 521, 2015
4XNX	X-ray structure of Drosophila dopamine transporter in complex with reboxetine 分子名称: (2R)-2-[(R)-(2-ethoxyphenoxy)(phenyl)methyl]morpholine, Antibody fragment heavy chain, CHLORIDE ION, ... 著者 Aravind, P, Wang, K, Gouaux, E. 登録日 2015-01-16 公開日 2015-05-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 X-ray structures of Drosophila dopamine transporter in complex with nisoxetine and reboxetine. Nat.Struct.Mol.Biol., 22, 2015
4XP6	X-ray structure of Drosophila dopamine transporter bound to psychostimulant methamphetamine 分子名称: (2S)-N-methyl-1-phenylpropan-2-amine, 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody fragment heavy chain-protein, ... 著者 Aravind, P, Wang, K, Gouaux, E. 登録日 2015-01-16 公開日 2015-05-13 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Neurotransmitter and psychostimulant recognition by the dopamine transporter. Nature, 521, 2015
4MM8	Crystal structure of LeuBAT (delta13 mutant) in complex with (R)-fluoxetine 分子名称: (3R)-N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine, SODIUM ION, Transporter 著者 Wang, H, Gouaux, E. 登録日 2013-09-08 公開日 2013-10-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.31 Å) 主引用文献 Structural basis for action by diverse antidepressants on biogenic amine transporters. Nature, 503, 2013
4MMF	Crystal structure of LeuBAT (delta5 mutant) in complex with mazindol 分子名称: (5R)-5-(4-chlorophenyl)-2,5-dihydro-3H-imidazo[2,1-a]isoindol-5-ol, SODIUM ION, Transporter, ... 著者 Wang, H, Gouaux, E. 登録日 2013-09-08 公開日 2013-10-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural basis for action by diverse antidepressants on biogenic amine transporters. Nature, 503, 2013
4MM4	Crystal structure of LeuBAT (delta13 mutant) in complex with paroxetine 分子名称: CHLORIDE ION, Paroxetine, SODIUM ION, ... 著者 Wang, H, Gouaux, E. 登録日 2013-09-08 公開日 2013-10-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.886 Å) 主引用文献 Structural basis for action by diverse antidepressants on biogenic amine transporters. Nature, 503, 2013
4XP9	X-ray structure of Drosophila dopamine transporter bound to psychostimulant D-amphetamine 分子名称: (2S)-1-phenylpropan-2-amine, 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Aravind, P, Wang, K, Gouaux, E. 登録日 2015-01-16 公開日 2015-05-06 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Neurotransmitter and psychostimulant recognition by the dopamine transporter. Nature, 521, 2015
4XPH	X-ray structure of Drosophila dopamine transporter with subsiteB mutations (D121G/S426M) bound to 3,4dichlorophenethylamine 分子名称: 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, 2-(3,4-dichlorophenyl)ethanamine, Antibody fragment heavy chain, ... 著者 Penmatsa, A, Wang, K, Gouaux, E. 登録日 2015-01-17 公開日 2015-05-06 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Neurotransmitter and psychostimulant recognition by the dopamine transporter. Nature, 521, 2015
4MM9	Crystal structure of LeuBAT (delta13 mutant) in complex with fluvoxamine 分子名称: Fluvoxamine, SODIUM ION, Transporter 著者 Wang, H, Gouaux, E. 登録日 2013-09-08 公開日 2013-10-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural basis for action by diverse antidepressants on biogenic amine transporters. Nature, 503, 2013
4XPA	X-ray structure of Drosophila dopamine transporter bound to 3,4dichlorophenethylamine 分子名称: 2-(3,4-dichlorophenyl)ethanamine, Antibody fragment heavy chain-protein, 9D5-heavy chain, ... 著者 Aravind, P, Wang, K, Gouaux, E. 登録日 2015-01-16 公開日 2015-05-20 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Neurotransmitter and psychostimulant recognition by the dopamine transporter. Nature, 521, 2015
4MM5	Crystal structure of LeuBAT (delta13 mutant) in complex with sertraline 分子名称: (1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine, SODIUM ION, Transporter 著者 Wang, H, Gouaux, E. 登録日 2013-09-08 公開日 2013-10-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural basis for action by diverse antidepressants on biogenic amine transporters. Nature, 503, 2013

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