7YSO
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7YSN
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7YOP
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7YLW
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7YHN
| ANTI-TUMOR AGENT Y48 IN COMPLEX WITH TUBULIN | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-methyl-3-[(4-methylphenyl)sulfonylamino]-~{N}-[(6-methylpyridin-3-yl)methyl]benzamide, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Du, T, Ji, M, Hou, Z, Lin, S, Zhang, J, Wu, D, Zhang, K, Lu, D, Xu, H, Chen, X. | 登録日 | 2022-07-14 | 公開日 | 2023-07-26 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Optimization of Benzamide Derivatives as Potent and Orally Active Tubulin Inhibitors Targeting the Colchicine Binding Site. J.Med.Chem., 65, 2022
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7XR1
| Crystal structure of T2R-TTL-3a complex | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-chloranyl-6-fluoranyl-N-(4-methoxyphenyl)-N-methyl-quinazolin-4-amine, CALCIUM ION, ... | 著者 | Lun, T, Wu, C.Y. | 登録日 | 2022-05-09 | 公開日 | 2023-05-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | 主引用文献 | Crystal structure of T2R-TTL-3a complex To Be Published
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7XR0
| Crystal structure of T2R-TTL-27a complex | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-chloranyl-5-fluoranyl-N-(4-methoxyphenyl)-N-methyl-quinazolin-4-amine, CALCIUM ION, ... | 著者 | Lun, T, Wu, C.Y. | 登録日 | 2022-05-09 | 公開日 | 2023-05-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal structure of T2R-TTL-27a complex To Be Published
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7XQY
| Crystal structure of T2R-TTL-15 complex | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-chloranyl-N-(4-methoxyphenyl)-N-methyl-pyrido[3,2-d]pyrimidin-4-amine, CALCIUM ION, ... | 著者 | Lun, T, ChengYong, W. | 登録日 | 2022-05-09 | 公開日 | 2023-05-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Crystal structure of T2R-TTL-15 complex To Be Published
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7XQX
| Crystal structure of T2R-TTL-27a complex | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-chloranyl-7-fluoranyl-N-(4-methoxyphenyl)-N-methyl-quinazolin-4-amine, CALCIUM ION, ... | 著者 | Lun, T, Wu, C.Y. | 登録日 | 2022-05-09 | 公開日 | 2023-05-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.36 Å) | 主引用文献 | Crystal structure of T2R-TT complex To Be Published
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7X4N
| Crystal Structure of C. elegans kinesin-4 KLP-12 complexed with tubulin and DARPin | 分子名称: | DARPin, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Taguchi, S, Imasaki, T, Saijo-Hamano, Y, Sakai, N, Nitta, R. | 登録日 | 2022-03-03 | 公開日 | 2022-09-21 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.88 Å) | 主引用文献 | Structural model of microtubule dynamics inhibition by kinesin-4 from the crystal structure of KLP-12 -tubulin complex. Elife, 11, 2022
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7X0S
| Human TRiC-tubulin-S3 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ... | 著者 | Cong, Y, Liu, C.X. | 登録日 | 2022-02-22 | 公開日 | 2023-04-12 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Pathway and mechanism of tubulin folding mediated by TRiC/CCT along its ATPase cycle revealed using cryo-EM. Commun Biol, 6, 2023
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7VMK
| Crystal structure of tubulin with 3 | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Jifa, Z, Lun, T. | 登録日 | 2021-10-08 | 公開日 | 2022-10-19 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure of tubulin with 3 To Be Published
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7VMJ
| Crystal structure of tubulin with 17a | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ... | 著者 | Jifa, Z, Lun, T. | 登録日 | 2021-10-08 | 公開日 | 2022-10-19 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystal structure of tubulin with 17j To Be Published
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7VMG
| Crystal structure of tubulin with 17j | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ... | 著者 | Jifa, Z, Lun, T. | 登録日 | 2021-10-08 | 公開日 | 2022-10-19 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | 主引用文献 | Crystal structure of tubulin with 17a To Be Published
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7UNG
| 48-nm repeat of the human respiratory doublet microtubule | 分子名称: | Cilia- and flagella-associated protein 161, Cilia- and flagella-associated protein 20, Cilia- and flagella-associated protein 45, ... | 著者 | Gui, M, Croft, J.T, Zabeo, D, Acharya, V, Kollman, J.M, Burgoyne, T, Hoog, J.L, Brown, A. | 登録日 | 2022-04-11 | 公開日 | 2022-10-05 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | SPACA9 is a lumenal protein of human ciliary singlet and doublet microtubules. Proc.Natl.Acad.Sci.USA, 119, 2022
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7UN1
| 8-nm repeat of the human sperm tip singlet microtubule | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Gui, M, Croft, J.T, Zabeo, D, Acharya, V, Kollman, J.M, Burgoyne, T, Hoog, J.L, Brown, A. | 登録日 | 2022-04-08 | 公開日 | 2022-10-05 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (6 Å) | 主引用文献 | SPACA9 is a lumenal protein of human ciliary singlet and doublet microtubules. Proc.Natl.Acad.Sci.USA, 119, 2022
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7U0F
| HIV-1 Rev in complex with tubulin | 分子名称: | Protein Rev, Tubulin alpha-1A chain, Tubulin beta chain | 著者 | Eren, E. | 登録日 | 2022-02-18 | 公開日 | 2023-08-23 | 最終更新日 | 2023-10-18 | 実験手法 | ELECTRON MICROSCOPY (3.53 Å) | 主引用文献 | Structural basis of microtubule depolymerization by the kinesin-like activity of HIV-1 Rev. Structure, 31, 2023
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7TUB
| The beta-tubulin folding intermediate IV | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ... | 著者 | Zhao, Y, Frydman, J, Chiu, W. | 登録日 | 2022-02-02 | 公開日 | 2022-12-28 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structural visualization of the tubulin folding pathway directed by human chaperonin TRiC/CCT. Cell, 185, 2022
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7TTT
| The beta-tubulin folding intermediate III | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ... | 著者 | Zhao, Y, Frydman, J, Chiu, W. | 登録日 | 2022-02-01 | 公開日 | 2022-12-28 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural visualization of the tubulin folding pathway directed by human chaperonin TRiC/CCT. Cell, 185, 2022
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7TTN
| The beta-tubulin folding intermediate II | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ... | 著者 | Zhao, Y, Frydman, J, Chiu, W. | 登録日 | 2022-02-01 | 公開日 | 2022-12-28 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural visualization of the tubulin folding pathway directed by human chaperonin TRiC/CCT. Cell, 185, 2022
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7TTF
| Tubulin-RB3_SLD in complex with compound 12k | 分子名称: | 7-methoxy-4-[2-(methylamino)-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl]-3,4-dihydroquinoxalin-2(1H)-one, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | White, S.W, Yun, M. | 登録日 | 2022-02-01 | 公開日 | 2023-04-12 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Design, Synthesis, and Biological Evaluation of Pyrimidine Dihydroquinoxalinone Derivatives as Tubulin Colchicine Site-Binding Agents That Displayed Potent Anticancer Activity Both In Vitro and In Vivo. Acs Pharmacol Transl Sci, 6, 2023
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7TTE
| Tubulin-RB3_SLD in complex with compound 12j | 分子名称: | 4-[2-(cyclopropylamino)-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl]-7-methoxy-3,4-dihydroquinoxalin-2(1H)-one, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | White, S.W, Yun, M. | 登録日 | 2022-02-01 | 公開日 | 2023-04-12 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Design, Synthesis, and Biological Evaluation of Pyrimidine Dihydroquinoxalinone Derivatives as Tubulin Colchicine Site-Binding Agents That Displayed Potent Anticancer Activity Both In Vitro and In Vivo. Acs Pharmacol Transl Sci, 6, 2023
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7TTD
| Tubulin-RB3_SLD in complex with compound 12e | 分子名称: | 7-methoxy-4-[2-(morpholin-4-yl)-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl]-3,4-dihydroquinoxalin-2(1H)-one, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | White, S.W, Yun, M. | 登録日 | 2022-02-01 | 公開日 | 2023-04-12 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | 主引用文献 | Design, Synthesis, and Biological Evaluation of Pyrimidine Dihydroquinoxalinone Derivatives as Tubulin Colchicine Site-Binding Agents That Displayed Potent Anticancer Activity Both In Vitro and In Vivo. Acs Pharmacol Transl Sci, 6, 2023
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7TRG
| The beta-tubulin folding intermediate I | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ... | 著者 | Zhao, Y, Frydman, J, Chiu, W. | 登録日 | 2022-01-28 | 公開日 | 2022-12-28 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural visualization of the tubulin folding pathway directed by human chaperonin TRiC/CCT. Cell, 185, 2022
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7TR3
| CaKip3[2-482] - AMP-PNP in complex with a dolastatin-10-stabilized tubulin ring | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein, ... | 著者 | Benoit, M.P.M.H, Asenjo, A.B, Hunter, B, Allingham, J.S, Sosa, H. | 登録日 | 2022-01-27 | 公開日 | 2022-07-20 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Kinesin-8-specific loop-2 controls the dual activities of the motor domain according to tubulin protofilament shape. Nat Commun, 13, 2022
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