PDB: 155 件ウェブページステータス検索Chemie searchBIRD

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5HD1	Crystal structure of antimicrobial peptide Pyrrhocoricin bound to the Thermus thermophilus 70S ribosome 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... 著者 Gagnon, M.G, Roy, R.N, Lomakin, I.B, Florin, T, Mankin, A.S, Steitz, T.A. 登録日 2016-01-04 公開日 2016-04-06 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structures of proline-rich peptides bound to the ribosome reveal a common mechanism of protein synthesis inhibition. Nucleic Acids Res., 44, 2016
8CVJ	Crystal structure of the Thermus thermophilus 70S ribosome in complex with mRNA, aminoacylated A-site Phe-NH-tRNAphe, peptidyl P-site fMSEAC-NH-tRNAmet, and deacylated E-site tRNAphe at 2.40A resolution 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... 著者 Syroegin, E.A, Aleksandrova, E.V, Polikanov, Y.S. 登録日 2022-05-18 公開日 2022-10-19 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Insights into the ribosome function from the structures of non-arrested ribosome-nascent chain complexes. Nat.Chem., 15, 2023
8CVL	Crystal structure of the Thermus thermophilus 70S ribosome in complex with mRNA, aminoacylated A-site Phe-NH-tRNAphe, peptidyl P-site fMTHSMRC-NH-tRNAmet, and deacylated E-site tRNAphe at 2.30A resolution 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... 著者 Syroegin, E.A, Aleksandrova, E.V, Polikanov, Y.S. 登録日 2022-05-18 公開日 2022-10-19 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Insights into the ribosome function from the structures of non-arrested ribosome-nascent chain complexes. Nat.Chem., 15, 2023
8CVK	Crystal structure of the Thermus thermophilus 70S ribosome in complex with mRNA, aminoacylated A-site Phe-NH-tRNAphe, peptidyl P-site fMRC-NH-tRNAmet, and deacylated E-site tRNAphe at 2.50A resolution 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... 著者 Syroegin, E.A, Aleksandrova, E.V, Polikanov, Y.S. 登録日 2022-05-18 公開日 2022-10-19 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Insights into the ribosome function from the structures of non-arrested ribosome-nascent chain complexes. Nat.Chem., 15, 2023
8EKB	Crystal structure of the Thermus thermophilus 70S ribosome in complex with mRNA, deacylated P-site tRNAmet, and thermorubin at 2.70A resolution 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... 著者 Paranjpe, M.N, Polikanov, Y.S. 登録日 2022-09-20 公開日 2022-12-21 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Insights into the molecular mechanism of translation inhibition by the ribosome-targeting antibiotic thermorubin. Nucleic Acids Res., 51, 2023
8FC1	Crystal structure of the Thermus thermophilus 70S ribosome in complex with protein Y, hygromycin A, and erythromycin at 2.50A resolution 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ... 著者 Chen, C.-W, Syroegin, E.A, Svetlov, M.S, Polikanov, Y.S. 登録日 2022-12-01 公開日 2023-07-12 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural insights into the mechanism of overcoming Erm-mediated resistance by macrolides acting together with hygromycin-A. Nat Commun, 14, 2023
8FC2	Crystal structure of the Thermus thermophilus 70S ribosome in complex with protein Y, hygromycin A, and azithromycin at 2.50A resolution 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ... 著者 Chen, C.-W, Syroegin, E.A, Svetlov, M.S, Polikanov, Y.S. 登録日 2022-12-01 公開日 2023-07-12 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural insights into the mechanism of overcoming Erm-mediated resistance by macrolides acting together with hygromycin-A. Nat Commun, 14, 2023
8FC6	Crystal structure of the A2058-N6-dimethylated Thermus thermophilus 70S ribosome in complex with protein Y, hygromycin A, and telithromycin at 2.35A resolution 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ... 著者 Chen, C.-W, Syroegin, E.A, Svetlov, M.S, Polikanov, Y.S. 登録日 2022-12-01 公開日 2023-07-26 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Structural insights into the mechanism of overcoming Erm-mediated resistance by macrolides acting together with hygromycin-A. Nat Commun, 14, 2023
8FC4	Crystal structure of the A2058-N6-dimethylated Thermus thermophilus 70S ribosome in complex with protein Y, hygromycin A, and erythromycin at 2.45A resolution 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ... 著者 Chen, C.-W, Syroegin, E.A, Svetlov, M.S, Polikanov, Y.S. 登録日 2022-12-01 公開日 2023-07-26 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Structural insights into the mechanism of overcoming Erm-mediated resistance by macrolides acting together with hygromycin-A. Nat Commun, 14, 2023
8FC5	Crystal structure of the A2058-N6-dimethylated Thermus thermophilus 70S ribosome in complex with protein Y, hygromycin A, and azithromycin at 2.65A resolution 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ... 著者 Chen, C.-W, Syroegin, E.A, Svetlov, M.S, Polikanov, Y.S. 登録日 2022-12-01 公開日 2023-07-26 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Structural insights into the mechanism of overcoming Erm-mediated resistance by macrolides acting together with hygromycin-A. Nat Commun, 14, 2023
8FC3	Crystal structure of the Thermus thermophilus 70S ribosome in complex with protein Y, hygromycin A, and telithromycin at 2.60A resolution 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ... 著者 Chen, C.-W, Syroegin, E.A, Svetlov, M.S, Polikanov, Y.S. 登録日 2022-12-01 公開日 2023-07-12 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural insights into the mechanism of overcoming Erm-mediated resistance by macrolides acting together with hygromycin-A. Nat Commun, 14, 2023
8EV6	Crystal structure of the Thermus thermophilus 70S ribosome in complex with amikacin, mRNA, and A-, P-, and E-site tRNAs 分子名称: (2S)-N-[(1R,2S,3S,4R,5S)-4-[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-5-azanyl-2-[(2S,3R,4S,5S ,6R)-4-azanyl-6-(hydroxymethyl)-3,5-bis(oxidanyl)oxan-2-yl]oxy-3-oxidanyl-cyclohexyl]-4-azanyl-2-oxidanyl-butanamide, 16S Ribosomal RNA, 23S Ribosomal RNA, ... 著者 Seely, S.M, Gagnon, M.G. 登録日 2022-10-19 公開日 2023-08-09 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.946 Å) 主引用文献 Molecular basis of the pleiotropic effects by the antibiotic amikacin on the ribosome. Nat Commun, 14, 2023
8EV7	Crystal structure of the Thermus thermophilus 70S ribosome in complex with kanamycin, mRNA, and A-, P-, and E-site tRNAs 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... 著者 Seely, S.M, Gagnon, M.G. 登録日 2022-10-19 公開日 2023-08-09 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.89 Å) 主引用文献 Molecular basis of the pleiotropic effects by the antibiotic amikacin on the ribosome. Nat Commun, 14, 2023
4U50	Crystal structure of Verrucarin bound to the yeast 80S ribosome 分子名称: (4S,5R,10E,12Z,16R,16aS,17S,18R,19aR,23aR)-4-hydroxy-5,16a,21-trimethyl-4,5,6,7,16,16a,22,23-octahydro-3H,18H,19aH-spiro[16,18-methano[1,6,12]trioxacyclooctadecino[3,4-d]chromene-17,2'-oxirane]-3,9,14-trione, 18S ribosomal RNA, 25S ribosomal RNA, ... 著者 Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. 登録日 2014-07-24 公開日 2014-10-22 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural basis for the inhibition of the eukaryotic ribosome. Nature, 513, 2014
4U4Y	Crystal structure of Pactamycin bound to the yeast 80S ribosome 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... 著者 Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. 登録日 2014-07-24 公開日 2014-10-22 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural basis for the inhibition of the eukaryotic ribosome. Nature, 513, 2014
4U53	Crystal structure of Deoxynivalenol bound to the yeast 80S ribosome 分子名称: (3beta,7alpha)-3,7,15-trihydroxy-12,13-epoxytrichothec-9-en-8-one, 18S ribosomal RNA, 25S ribosomal RNA, ... 著者 Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. 登録日 2014-07-24 公開日 2014-10-22 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Structural basis for the inhibition of the eukaryotic ribosome. Nature, 513, 2014
4U56	Crystal structure of Blasticidin S bound to the yeast 80S ribosome 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... 著者 Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. 登録日 2014-07-24 公開日 2014-10-22 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.45 Å) 主引用文献 Structural basis for the inhibition of the eukaryotic ribosome. Nature, 513, 2014
4U51	Crystal structure of Narciclasine bound to the yeast 80S ribosome 分子名称: (2S,3R,4S,4aR)-2,3,4,7-tetrahydroxy-3,4,4a,5-tetrahydro[1,3]dioxolo[4,5-j]phenanthridin-6(2H)-one, 18S ribosomal RNA, 25S ribosomal RNA, ... 著者 Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. 登録日 2014-07-24 公開日 2014-10-22 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural basis for the inhibition of the eukaryotic ribosome. Nature, 513, 2014
4U4O	Crystal structure of Geneticin bound to the yeast 80S ribosome 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... 著者 Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. 登録日 2014-07-24 公開日 2014-10-22 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Structural basis for the inhibition of the eukaryotic ribosome. Nature, 513, 2014
4U4R	Crystal structure of Lactimidomycin bound to the yeast 80S ribosome 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 4-{(2R,5S,6E)-2-hydroxy-5-methyl-7-[(2R,3S,4E,6Z,10E)-3-methyl-12-oxooxacyclododeca-4,6,10-trien-2-yl]-4-oxooct-6-en-1-yl}piperidine-2,6-dione, ... 著者 Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. 登録日 2014-07-24 公開日 2014-10-22 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.801 Å) 主引用文献 Structural basis for the inhibition of the eukaryotic ribosome. Nature, 513, 2014
4U52	Crystal structure of Nagilactone C bound to the yeast 80S ribosome 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... 著者 Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. 登録日 2014-07-24 公開日 2014-10-22 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural basis for the inhibition of the eukaryotic ribosome. Nature, 513, 2014
4U4N	Crystal structure of Edeine bound to the yeast 80S ribosome 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... 著者 Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. 登録日 2014-07-24 公開日 2014-10-22 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structural basis for the inhibition of the eukaryotic ribosome. Nature, 513, 2014
4U3M	Crystal structure of Anisomycin bound to the yeast 80S ribosome 分子名称: 18S rRNA, 25s rRNA, 40S ribosomal protein S0-A, ... 著者 Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. 登録日 2014-07-22 公開日 2014-10-22 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural basis for the inhibition of the eukaryotic ribosome. Nature, 513, 2014
4U4Q	Crystal structure of Homoharringtonine bound to the yeast 80S ribosome 分子名称: (3beta)-O~3~-[(2R)-2,6-dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methylheptanoyl]cephalotaxine, 18S ribosomal RNA, 25S ribosomal RNA, ... 著者 Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. 登録日 2014-07-24 公開日 2014-10-22 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural basis for the inhibition of the eukaryotic ribosome. Nature, 513, 2014
4U3N	Crystal structure of CCA trinucleotide bound to the yeast 80S ribosome 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... 著者 Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. 登録日 2014-07-22 公開日 2014-10-22 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural basis for the inhibition of the eukaryotic ribosome. Nature, 513, 2014

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