8FSW
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5JB9
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6WC2
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8FSU
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8FSV
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8FST
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8HY7
| EGFR kinase domain mutant "TMLR" with compound 28f | 分子名称: | Epidermal growth factor receptor, ~{N}-[3-[[6-fluoranyl-2-[[4-(4-methylpiperazin-1-yl)phenyl]amino]quinazolin-4-yl]amino]phenyl]prop-2-enamide | 著者 | Wang, Y.X, Wu, C.Y. | 登録日 | 2023-01-06 | 公開日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.91 Å) | 主引用文献 | The crystal structure of EGFR kinase domain(T790M/L858R) in complex with compound 28f To Be Published
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4ZFL
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5JAW
| Structure of a beta galactosidase with inhibitor | 分子名称: | (1S,2S,3S,4S,5R,6R)-5-amino-6-(hydroxymethyl)cyclohexane-1,2,3,4-tetrol, ACETATE ION, Beta-galactosidase, ... | 著者 | Offen, W, Davies, G. | 登録日 | 2016-04-12 | 公開日 | 2017-05-10 | 最終更新日 | 2024-10-23 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Towards broad spectrum activity-based glycosidase probes: synthesis and evaluation of deoxygenated cyclophellitol aziridines. Chem. Commun. (Camb.), 53, 2017
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8FT0
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8FSY
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8FSX
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4ZH7
| Structural basis of Lewisb antigen binding by the Helicobacter pylori adhesin BabA | 分子名称: | Outer membrane protein-adhesin, alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-3)-[alpha-L-fucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose | 著者 | Howard, T, Hage, N, Phillips, C, Brassington, C.A, Debreczeni, J, Overman, R, Gellert, P, Stolnik, S, Winkler, G.S, Falcone, F.H. | 登録日 | 2015-04-24 | 公開日 | 2015-08-19 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | Structural basis of Lewis(b) antigen binding by the Helicobacter pylori adhesin BabA. Sci Adv, 1, 2015
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5JC9
| Structure of the Escherichia coli ribosome with the U1052G mutation in the 16S rRNA | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 1,4-DIAMINOBUTANE, ... | 著者 | Cocozaki, A, Ferguson, A. | 登録日 | 2016-04-14 | 公開日 | 2016-07-06 | 最終更新日 | 2016-08-03 | 実験手法 | X-RAY DIFFRACTION (3.03 Å) | 主引用文献 | Resistance mutations generate divergent antibiotic susceptibility profiles against translation inhibitors. Proc.Natl.Acad.Sci.USA, 113, 2016
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8FT3
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8I34
| The crystal structure of EPD-BCP1 from a marine sponge | 分子名称: | (2~{Z},4~{E},6~{E},8~{E},10~{E},12~{E},14~{E},16~{E})-4,8,13,17-tetramethyl-3-oxidanyl-19-[(4~{R})-2,6,6-trimethyl-4-oxidanyl-cyclohexen-1-yl]-1-[(1~{R},4~{S})-1,2,2-trimethyl-4-oxidanyl-cyclopentyl]nonadeca-2,4,6,8,10,12,14,16-octaen-18-yn-1-one, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ASTAXANTHIN, ... | 著者 | Shomura, Y, Kawasaki, S. | 登録日 | 2023-01-16 | 公開日 | 2023-08-16 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | 主引用文献 | An ependymin-related blue carotenoprotein decorates marine blue sponge. J.Biol.Chem., 299, 2023
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8IC1
| endo-alpha-D-arabinanase EndoMA1 D51N mutant from Microbacterium arabinogalactanolyticum in complex with arabinooligosaccharides | 分子名称: | (3~{a}~{S},5~{R},6~{R},6~{a}~{S})-5-(hydroxymethyl)-2,2-dimethyl-3~{a},5,6,6~{a}-tetrahydrofuro[2,3-d][1,3]dioxol-6-ol, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | 著者 | Li, J, Nakashima, C, Ishiwata, A, Fujita, K, Fushinobu, S. | 登録日 | 2023-02-10 | 公開日 | 2023-08-16 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Identification and characterization of endo-alpha-, exo-alpha-, and exo-beta-D-arabinofuranosidases degrading lipoarabinomannan and arabinogalactan of mycobacteria. Nat Commun, 14, 2023
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8FYZ
| Crystal structure of human PARP1 ART domain bound to inhibitor UKTT10 (compound 13) | 分子名称: | (2P)-2-{3-[(4R)-3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-carbonyl]phenyl}-1H-benzimidazole-4-carboxamide, CITRIC ACID, DIMETHYL SULFOXIDE, ... | 著者 | Rouleau-Turcotte, E, Pascal, J.M. | 登録日 | 2023-01-27 | 公開日 | 2024-02-07 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Novel modifications of PARP inhibitor veliparib increase PARP1 binding to DNA breaks. Biochem.J., 481, 2024
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5JGZ
| Spin-Labeled T4 Lysozyme Construct T151V1 | 分子名称: | CHLORIDE ION, Endolysin, HEXANE-1,6-DIOL, ... | 著者 | Balo, A.R, Feyrer, H, Ernst, O.P. | 登録日 | 2016-04-20 | 公開日 | 2017-02-15 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.534 Å) | 主引用文献 | Toward Precise Interpretation of DEER-Based Distance Distributions: Insights from Structural Characterization of V1 Spin-Labeled Side Chains. Biochemistry, 55, 2016
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8FT1
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6WGB
| Crystal structure of the fab portion of dupilumab | 分子名称: | Dupilumab Fab heavy chain, Dupilumab Fab light chain | 著者 | Druzina, Z, Atwell, S, Pustilnik, A, Antonysamy, S, Ho, C, Lieu, R, Hendle, J, Benach, J, Wang, J. | 登録日 | 2020-04-05 | 公開日 | 2020-09-16 | 最終更新日 | 2020-09-23 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Rapid and robust antibody Fab fragment crystallization utilizing edge-to-edge beta-sheet packing. Plos One, 15, 2020
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8IIA
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8FZ8
| Structure of cytochrome P450sky2 | 分子名称: | Cytochrome P450, OCTANOIC ACID (CAPRYLIC ACID), PROTOPORPHYRIN IX CONTAINING FE | 著者 | Murarka, V.C, Poulos, T.L. | 登録日 | 2023-01-27 | 公開日 | 2024-02-07 | 最終更新日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | 主引用文献 | Biosynthesis of a new skyllamycin in Streptomyces nodosus : a cytochrome P450 forms an epoxide in the cinnamoyl chain. Org.Biomol.Chem., 22, 2024
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8IC7
| exo-beta-D-arabinofuranosidase ExoMA2 from Microbacterium arabinogalactanolyticum in complex with beta-D-arabinofuranose | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, MAGNESIUM ION, ... | 著者 | Fukushima, R, Kashima, T, Ishiwata, A, Fujita, K, Fushinobu, S. | 登録日 | 2023-02-11 | 公開日 | 2023-08-16 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Identification and characterization of endo-alpha-, exo-alpha-, and exo-beta-D-arabinofuranosidases degrading lipoarabinomannan and arabinogalactan of mycobacteria. Nat Commun, 14, 2023
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8FK9
| Crystal Structure of the Tick Evasin EVA-ACA1001 Complexed to Human Chemokine CCL16 | 分子名称: | C-C motif chemokine 16, Evasin P991 | 著者 | Devkota, S.R, Bhusal, R.P, Aryal, P, Wilce, M.C.J, Stone, M.J. | 登録日 | 2022-12-21 | 公開日 | 2024-01-17 | 最終更新日 | 2024-07-31 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural basis of chemokine recognition by the class A3 tick evasin EVA-ACA1001. Protein Sci., 33, 2024
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