4ZFL

Ergothioneine-biosynthetic Ntn hydrolase variant EgtC_C2A with natural substrate

Summary for 4ZFL

• Entry DOI: 10.2210/pdb4zfl/pdb
• Related: 4ZFJ 4ZFK
• Descriptor: Amidohydrolase EgtC, (1S)-1-carboxy-4-({(1R)-1-carboxy-2-[(S)-{4-[(2S)-2-carboxy-2-(trimethylammonio)ethyl]-1H-imidazol-2-yl}sulfinyl]ethyl}amino)-4-oxobutan-1-aminium, GLYCEROL, ... (4 entities in total)
• Functional Keywords: ntn hydrolase, ergothioneine biosynthesis, sulfur chemistry, mycobacteria, hydrolase
• Biological source: Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
• Total number of polymer chains: 12
• Total formula weight: 306856.74

Authors

Vit, A.,Seebeck, F.P.,Blankenfeldt, W. (deposition date: 2015-04-21, release date: 2015-07-01, Last modification date: 2024-01-10)

• Primary citation: Vit, A.,Mashabela, G.T.,Blankenfeldt, W.,Seebeck, F.P.; Structure of the Ergothioneine-Biosynthesis Amidohydrolase EgtC.; Chembiochem, 16:1490-1496, 2015; PubMed: 26079795; DOI: 10.1002/cbic.201500168

Experimental method

X-RAY DIFFRACTION (1.7 Å)