5JB9
Crystal structure of factor IXa K98T variant in complex with PPACK
Summary for 5JB9
Entry DOI | 10.2210/pdb5jb9/pdb |
Related PRD ID | PRD_000020 |
Descriptor | Coagulation factor IX, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, CALCIUM ION, ... (6 entities in total) |
Functional Keywords | blood clotting, hydrolase, glycoprotein, haemostasis |
Biological source | Homo sapiens (Human) More |
Cellular location | Secreted : P00740 P00740 |
Total number of polymer chains | 2 |
Total formula weight | 33130.23 |
Authors | Kristensen, L.H.,Brandstetter, H. (deposition date: 2016-04-13, release date: 2016-06-01, Last modification date: 2024-01-10) |
Primary citation | Kristensen, L.H.,Olsen, O.H.,Blouse, G.E.,Brandstetter, H. Releasing the brakes in coagulation Factor IXa by co-operative maturation of the substrate-binding site. Biochem.J., 473:2395-2411, 2016 Cited by PubMed: 27208168DOI: 10.1042/BCJ20160336 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.3 Å) |
Structure validation
Download full validation report