PDB: 13258 件ウェブページステータス検索Chemie searchBIRD

---

3GXW	Structure of the SH2 domain of the Candida glabrata transcription elongation factor Spt6, crystal form A 分子名称: SODIUM ION, SUCCINIC ACID, Transcription elongation factor SPT6 著者 Dengl, S, Mayer, A, Sun, M, Cramer, P. 登録日 2009-04-03 公開日 2009-05-26 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure and in vivo requirement of the yeast Spt6 SH2 domain J.Mol.Biol., 389, 2009
3KAD	Structure-guided design of alpha-amino acid-derived Pin1 inhibitors 分子名称: 3-(1H-benzimidazol-2-yl)-N-(3-phenylpropanoyl)-D-alanine, DODECAETHYLENE GLYCOL, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 著者 Baker, L.M, Dokurno, P, Robinson, D.A, Surgenor, A.E, Murray, J.B, Potter, A.J, Moore, J.D. 登録日 2009-10-19 公開日 2009-12-22 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structure-guided design of alpha-amino acid-derived Pin1 inhibitors Bioorg.Med.Chem.Lett., 20, 2010
3JA8	Cryo-EM structure of the MCM2-7 double hexamer 分子名称: ADENOSINE-5'-DIPHOSPHATE, Minichromosome Maintenance 2, Minichromosome Maintenance 3, ... 著者 Li, N, Zhai, Y, Zhang, Y, Li, W, Yang, M, Lei, J, Tye, B.K, Gao, N. 登録日 2015-05-09 公開日 2015-08-05 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structure of the eukaryotic MCM complex at 3.8 angstrom Nature, 524, 2015
3KAB	Structure-guided design of alpha-amino acid-derived Pin1 inhibitors 分子名称: 6-methyl-1H-indole-2-carboxylic acid, DODECAETHYLENE GLYCOL, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, ... 著者 Baker, L.M, Dokurno, P, Robinson, D.A, Surgenor, A.E, Murray, J.B, Potter, A.J, Moore, J.D. 登録日 2009-10-19 公開日 2009-12-22 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.19 Å) 主引用文献 Structure-guided design of alpha-amino acid-derived Pin1 inhibitors Bioorg.Med.Chem.Lett., 20, 2010
3WWQ	Crystal structure of FAAP20 UBZ domain in complex with Lys63-linked diubiquitin 分子名称: Fanconi anemia-associated protein of 20 kDa, Ubiquitin, ZINC ION 著者 Sato, Y, Fukai, S. 登録日 2014-06-23 公開日 2015-05-13 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural Basis for Ubiquitin Recognition by Ubiquitin-Binding Zinc Finger of FAAP20 Plos One, 10, 2015
3KAG	Structure-guided design of alpha-amino acid-derived Pin1 inhibitors 分子名称: 3-(1H-benzimidazol-2-yl)-N-[(2-methylfuran-3-yl)carbonyl]-D-alanine, DODECAETHYLENE GLYCOL, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 著者 Baker, L.M, Dokurno, P, Robinson, D.A, Surgenor, A.E, Murray, J.B, Potter, A.J, Moore, J.D. 登録日 2009-10-19 公開日 2009-12-22 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure-guided design of alpha-amino acid-derived Pin1 inhibitors Bioorg.Med.Chem.Lett., 20, 2010
3KCE	Structure-guided design of alpha-amino acid-derived Pin1 inhibitors 分子名称: 5-methyl-1H-indole-2-carboxylic acid, DODECAETHYLENE GLYCOL, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 著者 Baker, L.M, Dokurno, P, Robinson, D.A, Surgenor, A.E, Murray, J.B, Potter, A.J, Moore, J.D. 登録日 2009-10-21 公開日 2009-12-22 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure-guided design of alpha-amino acid-derived Pin1 inhibitors Bioorg.Med.Chem.Lett., 20, 2010
3DBL	Structural Dissection of a Gating Mechanism Preventing Misactivation of Ubiquitin by NEDD8's E1 (APPBP1-UBA3Arg190wt-NEDD8Ala72Gln) 分子名称: NEDD8, NEDD8-activating enzyme E1 catalytic subunit, NEDD8-activating enzyme E1 regulatory subunit, ... 著者 Souphron, J, Schulman, B.A. 登録日 2008-06-01 公開日 2008-08-12 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural dissection of a gating mechanism preventing misactivation of ubiquitin by NEDD8's E1. Biochemistry, 47, 2008
3DBH	Structural Dissection of a Gating Mechanism Preventing Misactivation of Ubiquitin by NEDD8's E1 (APPBP1-UBA3Arg190Ala-NEDD8Ala72Arg) 分子名称: NEDD8, NEDD8-activating enzyme E1 catalytic subunit, NEDD8-activating enzyme E1 regulatory subunit, ... 著者 Souphron, J, Schulman, B.A. 登録日 2008-05-31 公開日 2008-08-12 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Structural dissection of a gating mechanism preventing misactivation of ubiquitin by NEDD8's E1. Biochemistry, 47, 2008
3LFS	Crystal structure of CDK2 with SAR37, an aminoindazole type inhibitor 分子名称: Cell division protein kinase 2, N-(6-chloro-5-phenyl-1H-indazol-3-yl)butanamide 著者 Dreyer, M.K, Wendt, K.U, Schimanski-Breves, S, Loenze, P. 登録日 2010-01-18 公開日 2010-03-02 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Rational design of potent GSK3beta inhibitors with selectivity for Cdk1 and Cdk2. Bioorg.Med.Chem.Lett., 20, 2010
3CB5	Crystal Structure of the S. pombe Peptidase Homology Domain of FACT complex subunit Spt16 (form A) 分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FACT complex subunit spt16 著者 Stuwe, T, Hothorn, M, Lejeune, E, Bortfeld-Miller, M, Scheffzek, K, Ladurner, A.G. 登録日 2008-02-21 公開日 2008-06-17 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 The FACT Spt16 "peptidase" domain is a histone H3-H4 binding module Proc.Natl.Acad.Sci.USA, 105, 2008
3LKX	Human nac dimerization domain 分子名称: Nascent polypeptide-associated complex subunit alpha, Transcription factor BTF3 著者 Liu, Y, Hu, Y, Li, X, Niu, L, Teng, M. 登録日 2010-01-28 公開日 2010-03-23 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The crystal structure of the human nascent polypeptide-associated complex domain reveals a nucleic acid-binding region on the NACA subunit Biochemistry, 49, 2010
3CBB	Crystal Structure of Hepatocyte Nuclear Factor 4alpha in complex with DNA: Diabetes Gene Product 分子名称: Hepatocyte Nuclear Factor 4-alpha promoter element DNA, Hepatocyte Nuclear Factor 4-alpha, DNA binding domain, ... 著者 Lu, P, Rha, G.B, Melikishvili, M, Adkins, B.C, Fried, M.G, Chi, Y.I. 登録日 2008-02-21 公開日 2008-10-07 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural basis of natural promoter recognition by a unique nuclear receptor, HNF4alpha. Diabetes gene product. J.Biol.Chem., 283, 2008
3C9C	Structural Basis of Histone H4 Recognition by p55 分子名称: CADMIUM ION, Chromatin assembly factor 1 p55 subunit, Histone H4, ... 著者 Song, J.J, Garlick, J.D, Kingston, R.E. 登録日 2008-02-15 公開日 2008-05-13 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural basis of histone H4 recognition by p55. Genes Dev., 22, 2008
3LFN	Crystal structure of CDK2 with SAR57, an aminoindazole type inhibitor 分子名称: Cell division protein kinase 2, N-[6-(4-hydroxyphenyl)-5-phenyl-1H-indazol-3-yl]butanamide 著者 Dreyer, M.K, Wendt, K.U, Schimanski-Breves, S, Loenze, P. 登録日 2010-01-18 公開日 2010-03-02 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Rational design of potent GSK3beta inhibitors with selectivity for Cdk1 and Cdk2. Bioorg.Med.Chem.Lett., 20, 2010
3CER	Crystal structure of the exopolyphosphatase-like protein Q8G5J2. Northeast Structural Genomics Consortium target BlR13 分子名称: Possible exopolyphosphatase-like protein, SULFATE ION 著者 Kuzin, A.P, Su, M, Chen, Y, Neely, H, Seetharaman, J, Shastry, R, Fang, Y, Cunningham, K, Ma, L.-C, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) 登録日 2008-02-29 公開日 2008-04-01 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of the exopolyphosphatase-like protein Q8G5J2. Northeast Structural Genomics Consortium target BlR13. To be Published
3CUQ	Integrated structural and functional model of the human ESCRT-II complex 分子名称: Vacuolar protein-sorting-associated protein 25, Vacuolar protein-sorting-associated protein 36, Vacuolar-sorting protein SNF8 著者 Im, Y.J, Hurley, J.H. 登録日 2008-04-16 公開日 2008-11-04 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.61 Å) 主引用文献 Integrated structural model and membrane targeting mechanism of the human ESCRT-II complex Dev.Cell, 14, 2008
3LE6	The structure of cyclin dependent kinase 2 (CKD2) with a pyrazolobenzodiazepine inhibitor 分子名称: 5-(2-chlorophenyl)-3-methyl-7-nitropyrazolo[3,4-b][1,4]benzodiazepine, Cell division protein kinase 2 著者 Lukacs, C.M, Swain, A, Crowther, R.L, Kammlott, R.U, Liu, J.J. 登録日 2010-01-14 公開日 2010-11-17 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Pyrazolobenzodiazepines: part I. Synthesis and SAR of a potent class of kinase inhibitors. Bioorg.Med.Chem.Lett., 20, 2010
3LW1	Binary complex of 14-3-3 sigma and p53 pT387-peptide 分子名称: 14-3-3 protein sigma, CHLORIDE ION, GLYCEROL, ... 著者 Schumacher, B, Mondry, J, Thiel, P, Weyand, M, Ottmann, C. 登録日 2010-02-23 公開日 2010-03-23 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.28 Å) 主引用文献 Structure of the p53 C-terminus bound to 14-3-3: Implications for stabilization of the p53 tetramer Febs Lett., 584, 2010
3LUE	Model of alpha-actinin CH1 bound to F-actin 分子名称: Actin, cytoplasmic 1, Alpha-actinin-3 著者 Galkin, V.E, Orlova, A, Salmazo, A, Djinovic-Carugo, K, Egelman, E.H. 登録日 2010-02-17 公開日 2010-04-28 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (15 Å) 主引用文献 Opening of tandem calponin homology domains regulates their affinity for F-actin. Nat.Struct.Mol.Biol., 17, 2010
3DXK	Structure of Bos Taurus Arp2/3 Complex with Bound Inhibitor CK0944636 分子名称: Actin-related protein 2, Actin-related protein 2/3 complex subunit 1B, Actin-related protein 2/3 complex subunit 2, ... 著者 Nolen, B.J, Tomasevic, N, Russell, A, Pierce, D.W, Jia, Z, Hartman, J, Sakowicz, R, Pollard, T.D. 登録日 2008-07-24 公開日 2009-07-28 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Characterization of two classes of small molecule inhibitors of Arp2/3 complex Nature, 460, 2009
3DTB	The structure of rat cytosolic PEPCK in complex with phosphoglycolate and GDP 分子名称: 2-PHOSPHOGLYCOLIC ACID, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, BICARBONATE ION, ... 著者 Sullivan, S.M, Holyoak, T. 登録日 2008-07-14 公開日 2008-08-26 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Enzymes with lid-gated active sites must operate by an induced fit mechanism instead of conformational selection. Proc.Natl.Acad.Sci.Usa, 105, 2008
6MQ7	Crystal structure of CLASP1 TOG2 domain at 1.78A resolution 分子名称: CLIP-associating protein 1 著者 Leano, J.B, Slep, K.C. 登録日 2018-10-09 公開日 2019-07-17 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Structures of TOG1 and TOG2 from the human microtubule dynamics regulator CLASP1. Plos One, 14, 2019
3MSH	Crystal structure of Hepatitis B X-Interacting Protein at high resolution 分子名称: GLYCEROL, Hepatitis B virus X-interacting protein, ISOPROPYL ALCOHOL, ... 著者 Garcia-Saez, I, Skoufias, D. 登録日 2010-04-29 公開日 2010-11-10 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.51 Å) 主引用文献 Structural Characterization of HBXIP: The Protein That Interacts with the Anti-Apoptotic Protein Survivin and the Oncogenic Viral Protein HBx. J.Mol.Biol., 405, 2011
3CB6	Crystal Structure of the S. pombe Peptidase Homology Domain of FACT complex subunit Spt16 (form B) 分子名称: FACT complex subunit spt16 著者 Stuwe, T, Hothorn, M, Lejeune, E, Bortfeld-Miller, M, Scheffzek, K, Ladurner, A.G. 登録日 2008-02-21 公開日 2008-06-17 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 The FACT Spt16 "peptidase" domain is a histone H3-H4 binding module Proc.Natl.Acad.Sci.USA, 105, 2008

<484485486487488489490491492493494495496497498499>