3LUE
Model of alpha-actinin CH1 bound to F-actin
Summary for 3LUE
Entry DOI | 10.2210/pdb3lue/pdb |
EMDB information | 5170 |
Descriptor | Actin, cytoplasmic 1, Alpha-actinin-3 (2 entities in total) |
Functional Keywords | calponin homology domains, acetylation, atp-binding, cytoplasm, cytoskeleton, methylation, nucleotide-binding, phosphoprotein, actin-binding, calcium, polymorphism, structural protein, deafness, disease mutation, dystonia |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 20 |
Total formula weight | 541231.77 |
Authors | Galkin, V.E.,Orlova, A.,Salmazo, A.,Djinovic-Carugo, K.,Egelman, E.H. (deposition date: 2010-02-17, release date: 2010-04-28, Last modification date: 2024-02-21) |
Primary citation | Galkin, V.E.,Orlova, A.,Salmazo, A.,Djinovic-Carugo, K.,Egelman, E.H. Opening of tandem calponin homology domains regulates their affinity for F-actin. Nat.Struct.Mol.Biol., 17:614-616, 2010 Cited by PubMed: 20383143DOI: 10.1038/nsmb.1789 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (15 Å) |
Structure validation
Download full validation report