PDB: 13258 件ウェブページステータス検索Chemie searchBIRD

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2H8R	Hepatocyte Nuclear Factor 1b bound to DNA: MODY5 Gene Product 分子名称: 5'-D(*CP*TP*TP*GP*GP*TP*TP*AP*AP*TP*AP*AP*TP*TP*CP*AP*CP*CP*AP*G)-3', 5'-D(*GP*CP*TP*GP*GP*TP*GP*AP*AP*TP*TP*AP*TP*TP*AP*AP*CP*CP*AP*A)-3', Hepatocyte nuclear factor 1-beta 著者 Lu, P, Rha, G.B, Chi, Y.I. 登録日 2006-06-07 公開日 2007-06-19 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural basis of disease-causing mutations in hepatocyte nuclear factor 1beta. Biochemistry, 46, 2007
4N9D	Fragment-based Design of 3-Aminopyridine-derived Amides as Potent Inhibitors of Human Nicotinamide Phosphoribosyltransferase (NAMPT) 分子名称: 1,2-ETHANEDIOL, 4-({[(4-tert-butylphenyl)sulfonyl]amino}methyl)-N-(pyridin-3-yl)benzamide, Nicotinamide phosphoribosyltransferase, ... 著者 Dragovich, P.S, Zhao, G, Baumeister, T, Bravo, B, Giannetti, A.M, Ho, Y, Hua, R, Li, G, Liang, X, O'Brien, T, Skelton, N.J, Wang, C, Zhao, Q, Oh, A, Wang, W, Wang, Y, Xiao, Y, Yuen, P, Zak, M, Zheng, X. 登録日 2013-10-20 公開日 2014-02-19 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.701 Å) 主引用文献 Fragment-based design of 3-aminopyridine-derived amides as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT). Bioorg.Med.Chem.Lett., 24, 2014
4MQW	Structure of follicle-stimulating hormone in complex with the entire ectodomain of its receptor (P31) 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Follicle-stimulating hormone receptor, ... 著者 Jiang, X, Liu, H, Chen, X, He, X. 登録日 2013-09-16 公開日 2014-04-09 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Evidence for Follicle-stimulating Hormone Receptor as a Functional Trimer. J.Biol.Chem., 289, 2014
2H1E	Tandem chromodomains of budding yeast CHD1 分子名称: Chromo domain protein 1 著者 Flanagan IV, J.F, Khorasanizadeh, S. 登録日 2006-05-16 公開日 2007-03-27 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Molecular Implications of Evolutionary Differences in CHD Double Chromodomains. J.Mol.Biol., 369, 2007
2JGZ	Crystal structure of phospho-CDK2 in complex with Cyclin B 分子名称: CELL DIVISION PROTEIN KINASE 2, G2/MITOTIC-SPECIFIC CYCLIN-B1 著者 Brown, N.R, Petri, E, Lowe, E.D, Skamnaki, V, Johnson, L.N. 登録日 2007-02-17 公開日 2007-05-22 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Cyclin B and cyclin A confer different substrate recognition properties on CDK2. Cell Cycle, 6, 2007
2K3Y	Solution structure of EAF3 chromo barrel domain bound to histone h3 with a dimethyllysine analog H3K36ME2 分子名称: Chromatin modification-related protein EAF3 著者 Mer, G, Xu, C. 登録日 2008-05-19 公開日 2008-09-16 最終更新日 2023-11-15 実験手法 SOLUTION NMR 主引用文献 Structural Basis for the Recognition of Methylated Histone H3K36 by the Eaf3 Subunit of Histone Deacetylase Complex Rpd3S. Structure, 16, 2008
4N9C	Fragment-based Design of 3-Aminopyridine-derived Amides as Potent Inhibitors of Human Nicotinamide Phosphoribosyltransferase (NAMPT) 分子名称: 5-nitro-1H-benzimidazole, Nicotinamide phosphoribosyltransferase, PHOSPHATE ION 著者 Dragovich, P.S, Zhao, G, Baumeister, T, Bravo, B, Giannetti, A.M, Ho, Y, Hua, R, Li, G, Liang, X, O'Brien, T, Skelton, N.J, Wang, C, Zhao, Q, Oh, A, Wang, W, Wang, Y, Xiao, Y, Yuen, P, Zak, M, Zheng, X. 登録日 2013-10-20 公開日 2014-02-19 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.751 Å) 主引用文献 Fragment-based design of 3-aminopyridine-derived amides as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT). Bioorg.Med.Chem.Lett., 24, 2014
2HOA	STRUCTURE DETERMINATION OF THE ANTP(C39->S) HOMEODOMAIN FROM NUCLEAR MAGNETIC RESONANCE DATA IN SOLUTION USING A NOVEL STRATEGY FOR THE STRUCTURE CALCULATION WITH THE PROGRAMS DIANA, CALIBA, HABAS AND GLOMSA 分子名称: ANTENNAPEDIA PROTEIN 著者 Guntert, P, Qian, Y.-Q, Otting, G, Muller, M, Gehring, W.J, Wuthrich, K. 登録日 1992-04-04 公開日 1993-10-31 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Structure determination of the Antp (C39----S) homeodomain from nuclear magnetic resonance data in solution using a novel strategy for the structure calculation with the programs DIANA, CALIBA, HABAS and GLOMSA. J.Mol.Biol., 217, 1991
2HWA	Crystal structure of Lys12Thr/Cys117Val mutant of human acidic fibroblast growth factor at 1.65 angstrom resolution. 分子名称: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION 著者 Dubey, V.K, Lee, J, Somasundaram, T, Blaber, M. 登録日 2006-08-01 公開日 2007-06-12 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Spackling the crack: stabilizing human fibroblast growth factor-1 by targeting the N and C terminus beta-strand interactions. J.Mol.Biol., 371, 2007
2HW9	Crystal structure of Lys12Cys/Cys117Val mutant of human acidic fibroblast Growth factor at 1.60 angstrom resolution. 分子名称: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION 著者 Dubey, V.K, Lee, J, Somasundaram, T, Blaber, M. 登録日 2006-08-01 公開日 2007-06-12 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Spackling the crack: stabilizing human fibroblast growth factor-1 by targeting the N and C terminus beta-strand interactions. J.Mol.Biol., 371, 2007
2JCW	REDUCED BRIDGE-BROKEN YEAST CU/ZN SUPEROXIDE DISMUTASE ROOM TEMPERATURE (298K) STRUCTURE 分子名称: COPPER (I) ION, CU/ZN SUPEROXIDE DISMUTASE, ZINC ION 著者 Hart, P.J, Balbirnie, M.M, Ogihara, N.L, Nersissian, A.M, Weiss, M.S, Valentine, J.S, Eisenberg, D. 登録日 1998-12-21 公開日 1999-06-08 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 A structure-based mechanism for copper-zinc superoxide dismutase. Biochemistry, 38, 1999
2JWT	Solution structure of Engrailed homeodomain WT 分子名称: Segmentation polarity homeobox protein engrailed 著者 Religa, T.L. 登録日 2007-10-24 公開日 2008-04-01 最終更新日 2024-05-08 実験手法 SOLUTION NMR 主引用文献 Comparison of multiple crystal structures with NMR data for engrailed homeodomain J.Biomol.Nmr, 40, 2008
2K40	NMR structure of HESX-1 homeodomain double mutant R31L/E42L 分子名称: Homeobox expressed in ES cells 1 著者 Asensio, J, Torrado, M, Gonzalez, C, Bastida, A. 登録日 2008-05-26 公開日 2009-05-05 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 The role of conserved salt-bridges on homeodomain stability To be Published
2LQW	Solution structure of phosphorylated CRKL 分子名称: Crk-like protein 著者 Jankowski, W, Saleh, T, Kalodimos, C. 登録日 2012-03-16 公開日 2012-05-16 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Domain organization differences explain Bcr-Abl's preference for CrkL over CrkII. Nat.Chem.Biol., 8, 2012
6IPU	Human nucleosome core particle containing 145 bp of DNA 分子名称: CHLORIDE ION, DNA (145-MER), Histone H2A type 1-B/E, ... 著者 DeFalco, L, Davey, C.A. 登録日 2018-11-04 公開日 2020-01-15 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 PARP1 exhibits enhanced association and catalytic efficiency with gamma H2A.X-nucleosome. Nat Commun, 10, 2019
7ACK	CDK2/cyclin A2 in complex with an imidazo[1,2-c]pyrimidin-5-one inhibitor 分子名称: 1,2-ETHANEDIOL, 8-cyclohexyl-6~{H}-imidazo[1,2-c]pyrimidin-5-one, Cyclin-A2, ... 著者 Skerlova, J, Pachl, P, Rezacova, P. 登録日 2020-09-11 公開日 2021-03-24 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Imidazo[1,2-c]pyrimidin-5(6H)-one inhibitors of CDK2: Synthesis, kinase inhibition and co-crystal structure. Eur.J.Med.Chem., 216, 2021
6ZVC	14-3-3 Sigma in complex with phosphorylated Gab2pT391 peptide - 48h incubation 分子名称: 14-3-3 protein sigma, MAGNESIUM ION, phosphorylated Gab2pT391 peptide 著者 Ballone, A, Lau, R.A, Zweipfenning, F.P.A, Ottmann, C. 登録日 2020-07-24 公開日 2021-08-04 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.51 Å) 主引用文献 A new soaking procedure for X-ray crystallography structural determination of protein-peptide complexes To Be Published
6ZVB	14-3-3 Sigma in complex with phosphorylated Gab2pT391 peptide - 24h incubation 分子名称: 14-3-3 protein sigma, MAGNESIUM ION, phosphorylated Gab2pT391 peptide 著者 Ballone, A, Lau, R.A, Zweipfenning, F.P.A, Ottmann, C. 登録日 2020-07-24 公開日 2021-08-04 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.51 Å) 主引用文献 A new soaking procedure for X-ray crystallography structural determination of protein-peptide complexes To Be Published
6ZVD	14-3-3 Sigma in complex with phosphorylated Gab2pT391 peptide - 96h incubation 分子名称: 14-3-3 protein sigma, MAGNESIUM ION, phosphorylated Gab2pT391 peptide 著者 Ballone, A, Lau, R.A, Zweipfenning, F.P.A, Ottmann, C. 登録日 2020-07-24 公開日 2021-08-04 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 A new soaking procedure for X-ray crystallography structural determination of protein-peptide complexes To Be Published
6ZVE	14-3-3 Sigma in complex with phosphorylated Gab2pT391 peptide - 1h incubation 分子名称: 14-3-3 protein sigma, MAGNESIUM ION, phosphorylated Gab2pT391 peptide 著者 Ballone, A, Lau, R.A, Zweipfenning, F.P.A, Ottmann, C. 登録日 2020-07-24 公開日 2021-08-04 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.51 Å) 主引用文献 A new soaking procedure for X-ray crystallography structural determination of protein-peptide complexes To Be Published
7AEW	14-3-3 sigma bound to bis-phosphorylated aminopeptidase N (APN, CD13) via canonical and non-canonical binding motifs 分子名称: 14-3-3 protein sigma, Aminopeptidase N, CHLORIDE ION, ... 著者 Kiehstaller, S, Hennig, S. 登録日 2020-09-18 公開日 2020-11-04 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 MMP activation-associated aminopeptidase N reveals a bivalent 14-3-3 binding motif. J.Biol.Chem., 295, 2020
7B5S	Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: CUL1-RBX1-ARIH1 Ariadne. Transition State 1 分子名称: Cullin-1, E3 ubiquitin-protein ligase ARIH1, E3 ubiquitin-protein ligase RBX1, ... 著者 Horn-Ghetko, D, Prabu, J.R, Schulman, B.A. 登録日 2020-12-07 公開日 2021-02-10 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Ubiquitin ligation to F-box protein targets by SCF-RBR E3-E3 super-assembly. Nature, 590, 2021
7B15	14-3-3sigma in complex with SHN3pT869 phosphopeptide crystal structure 分子名称: 14-3-3 protein sigma, MAGNESIUM ION, SHN3pT869 著者 Soini, L, Leysen, S, Davis, J, Ottmann, C. 登録日 2020-11-23 公開日 2021-09-29 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.59 Å) 主引用文献 14-3-3 sigma in complex with phosphopeptides To Be Published
7B13	14-3-3sigma in complex with SHN3pS542 phosphopeptide crystal structure 分子名称: 14-3-3 protein sigma, MAGNESIUM ION, SHN3pS542 著者 Soini, L, Leysen, S, Davis, J, Ottmann, C. 登録日 2020-11-23 公開日 2021-09-29 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.37 Å) 主引用文献 14-3-3 sigma in complex with phosphopeptides To Be Published
6JXD	Human nucleosome core particle with cohesive end DNA termini 分子名称: DNA (147-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... 著者 DeFalco, L, Davey, C.A. 登録日 2019-04-23 公開日 2020-01-15 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 PARP1 exhibits enhanced association and catalytic efficiency with gamma H2A.X-nucleosome. Nat Commun, 10, 2019

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