7AEW

14-3-3 sigma bound to bis-phosphorylated aminopeptidase N (APN, CD13) via canonical and non-canonical binding motifs

This is a non-PDB format compatible entry.

Summary for 7AEW

• Entry DOI: 10.2210/pdb7aew/pdb
• Related: 6xwd
• Descriptor: 14-3-3 protein sigma, Aminopeptidase N, SODIUM ION, ... (5 entities in total)
• Functional Keywords: extracellular 14-3-3, phosphorylation, aminopeptidase n, cd13, protein binding, peptide binding protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 34808.54

Authors

Kiehstaller, S.,Hennig, S. (deposition date: 2020-09-18, release date: 2020-11-04, Last modification date: 2024-01-31)

• Primary citation: Kiehstaller, S.,Ottmann, C.,Hennig, S.; MMP activation-associated aminopeptidase N reveals a bivalent 14-3-3 binding motif.; J.Biol.Chem., 295:18266-18275, 2020; PubMed: 33109610; DOI: 10.1074/jbc.RA120.014708

Experimental method

X-RAY DIFFRACTION (1.2 Å)