7AEW
14-3-3 sigma bound to bis-phosphorylated aminopeptidase N (APN, CD13) via canonical and non-canonical binding motifs
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (AAA) | 14-3-3 protein sigma | polymer | 236 | 26542.9 | 1 | UniProt (P31947) Pfam (PF00244) | Homo sapiens (Human) | Epithelial cell marker protein 1,Stratifin |
| 2 | B, C (CCC, BBB) | Aminopeptidase N | polymer | 38 | 4069.1 | 2 | UniProt (P15144) | Homo sapiens | hAPN,Alanyl aminopeptidase,Aminopeptidase M,AP-M,Microsomal aminopeptidase,Myeloid plasma membrane glycoprotein CD13,gp150 |
| 3 | D, E, F, G (AAA) | SODIUM ION | non-polymer | 23.0 | 4 | Chemie (NA) | |||
| 4 | H (AAA) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | I, J, K (AAA, CCC, BBB) | water | water | 18.0 | 426 | Chemie (HOH) |
Sequence modifications
AAA: 1 - 231 (UniProt: P31947)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Met -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 34681.1 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 127.4 | |
| All* | Total formula weight | 34808.5 |
