PDB: 2705 件ウェブページステータス検索Chemie searchBIRD

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8P8M	Yeast 60S ribosomal subunit, RPL39 deletion 分子名称: 25S rRNA, 5.8S rRNA, 5S rRNA, ... 著者 Rabl, J, Banerjee, A, Boehringer, D, Zavolan, M. 登録日 2023-06-01 公開日 2024-06-12 実験手法 ELECTRON MICROSCOPY (2.66 Å) 主引用文献 Yeast 60S ribosomal subunit, RPL39 deletion To Be Published
8CVM	Cutibacterium acnes 50S ribosomal subunit with P-site tRNA and Sarecycline bound in the local refined map 分子名称: 23S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... 著者 Lomakin, I.B, Devarkar, S.C, Bunick, C.G. 登録日 2022-05-18 公開日 2023-03-15 最終更新日 2023-04-19 実験手法 ELECTRON MICROSCOPY (2.66 Å) 主引用文献 Sarecycline inhibits protein translation in Cutibacterium acnes 70S ribosome using a two-site mechanism. Nucleic Acids Res., 51, 2023
6XZA	E. coli 70S ribosome in complex with dirithromycin, and deacylated tRNA(iMet) (focused classification). 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Pichkur, E.B, Polikanov, Y.S, Myasnikov, A.G, Konevega, A.L. 登録日 2020-02-03 公開日 2020-11-04 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (2.66 Å) 主引用文献 Insights into the improved macrolide inhibitory activity from the high-resolution cryo-EM structure of dirithromycin bound to the E. coli 70S ribosome. Rna, 26, 2020
7M4X	A. baumannii Ribosome-Eravacycline complex: P-site tRNA 70S 分子名称: 16s Ribosomal RNA, 23s ribosomal RNA, 30S ribosomal protein S10, ... 著者 Morgan, C.E, Yu, E.W. 登録日 2021-03-22 公開日 2021-05-19 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (2.66 Å) 主引用文献 Cryo-EM Determination of Eravacycline-Bound Structures of the Ribosome and the Multidrug Efflux Pump AdeJ of Acinetobacter baumannii. Mbio, 12, 2021
8V87	60S ribosome biogenesis intermediate (Dbp10 post-catalytic structure - Overall map) 分子名称: 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 25S ribosomal RNA, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, ... 著者 Cruz, V.E, Weirich, C.S, Peddada, N, Erzberger, J.P. 登録日 2023-12-04 公開日 2024-05-01 実験手法 ELECTRON MICROSCOPY (2.66 Å) 主引用文献 The DEAD-box ATPase Dbp10/DDX54 initiates peptidyl transferase center formation during 60S ribosome biogenesis. Nat Commun, 15, 2024
7N30	Elongating 70S ribosome complex in a hybrid-H2* pre-translocation (PRE-H2*) conformation 分子名称: 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ... 著者 Rundlet, E.J, Holm, M, Schacherl, M, Natchiar, K.S, Altman, R.B, Spahn, C.M.T, Myasnikov, A.G, Blanchard, S.C. 登録日 2021-05-30 公開日 2021-07-14 最終更新日 2021-08-11 実験手法 ELECTRON MICROSCOPY (2.66 Å) 主引用文献 Structural basis of early translocation events on the ribosome. Nature, 595, 2021
6SXN	Crystal structure of P212121 apo form of CrtE 分子名称: Geranylgeranyl pyrophosphate synthase 著者 Feng, Y, Morgan, R.M.L, Nixon, P.J. 登録日 2019-09-26 公開日 2020-06-24 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.66 Å) 主引用文献 Crystal Structure of Geranylgeranyl Pyrophosphate Synthase (CrtE) Involved in Cyanobacterial Terpenoid Biosynthesis. Front Plant Sci, 11, 2020
7Q0R	Structure of the Candida albicans 80S ribosome in complex with blasticidin s 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0, ... 著者 Kolosova, O, Zgadzay, Y, Stetsenko, A, Jenner, L, Guskov, A, Yusupova, G, Yusupov, M. 登録日 2021-10-16 公開日 2022-05-25 最終更新日 2022-06-08 実験手法 ELECTRON MICROSCOPY (2.67 Å) 主引用文献 E-site drug specificity of the human pathogen Candida albicans ribosome. Sci Adv, 8, 2022
8FL2	Human nuclear pre-60S ribosomal subunit (State I1) 分子名称: 28S rRNA, 5.8S rRNA, 5S rRNA, ... 著者 Vanden Broeck, A, Klinge, S. 登録日 2022-12-21 公開日 2023-07-12 最終更新日 2023-07-19 実験手法 ELECTRON MICROSCOPY (2.67 Å) 主引用文献 Principles of human pre-60 S biogenesis. Science, 381, 2023
8FKY	Human nucleolar pre-60S ribosomal subunit (State F) 分子名称: 28S rRNA, 5.8S rRNA, 60S ribosomal protein L10a, ... 著者 Vanden Broeck, A, Klinge, S. 登録日 2022-12-21 公開日 2023-07-12 最終更新日 2023-07-19 実験手法 ELECTRON MICROSCOPY (2.67 Å) 主引用文献 Principles of human pre-60 S biogenesis. Science, 381, 2023
8JDM	Structure of the Human cytoplasmic Ribosome with human tRNA Tyr(GalQ34) and mRNA(UAU) (rotated state) 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... 著者 Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T. 登録日 2023-05-14 公開日 2023-12-06 最終更新日 2023-12-27 実験手法 ELECTRON MICROSCOPY (2.67 Å) 主引用文献 Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth. Cell, 186, 2023
4WFS	Crystal Structure of tRNA-dihydrouridine(20) synthase catalytic domain 分子名称: CHLORIDE ION, FLAVIN MONONUCLEOTIDE, SULFATE ION, ... 著者 Bou-Nader, C, Pecqueur, L, Kamah, A, Bregeon, D, Golinelli-Pimpaneau, B, Guimaraes, B.G, Fontecave, M, Hamdane, D. 登録日 2014-09-17 公開日 2015-10-07 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.68 Å) 主引用文献 An extended dsRBD is required for post-transcriptional modification in human tRNAs. Nucleic Acids Res., 43, 2015
5H9D	Crystal structure of Heptaprenyl Diphosphate Synthase from Staphylococcus aureus 分子名称: C-terminal peptide from Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 family protein, Farnesyl pyrophosphate synthetase, Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 family protein, ... 著者 Wei, H.L, Liu, W.D, Zheng, Y.Y, Ko, T.P, Chen, C.C, Guo, R.T. 登録日 2015-12-28 公開日 2016-12-28 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.68 Å) 主引用文献 Structure, Function, and Inhibition of Staphylococcus aureus Heptaprenyl Diphosphate Synthase ChemMedChem, 11, 2016
8HU1	E. coli 70S ribosome complexed with tRNA_Ile2 bearing L34 and ct6A37 in classical state 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Akiyama, N, Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T. 登録日 2022-12-22 公開日 2024-04-03 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (2.69 Å) 主引用文献 Structural insights into the decoding capability of isoleucine tRNAs with lysidine and agmatidine. Nat.Struct.Mol.Biol., 31, 2024
6Z3T	Structure of canine Sec61 inhibited by mycolactone 分子名称: Protein transport protein Sec61 subunit alpha isoform 1, Protein transport protein Sec61 subunit beta, Protein transport protein Sec61 subunit gamma, ... 著者 Gerard, S.F, Higgins, M.K. 登録日 2020-05-21 公開日 2020-07-22 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (2.69 Å) 主引用文献 Structure of the Inhibited State of the Sec Translocon. Mol.Cell, 79, 2020
3JWN	Complex of FimC, FimF, FimG and FimH 分子名称: Chaperone protein fimC, FimH protein, GLYCEROL, ... 著者 Le Trong, I, Aprikian, P, Stenkamp, R.E, Sokurenko, E.V. 登録日 2009-09-18 公開日 2010-06-16 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.69 Å) 主引用文献 Structural basis for mechanical force regulation of the adhesin FimH via finger trap-like beta sheet twisting. Cell(Cambridge,Mass.), 141, 2010
7N31	Elongating 70S ribosome complex in a post-translocation (POST) conformation 分子名称: 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ... 著者 Rundlet, E.J, Holm, M, Schacherl, M, Natchiar, K.S, Altman, R.B, Spahn, C.M.T, Myasnikov, A.G, Blanchard, S.C. 登録日 2021-05-31 公開日 2021-07-14 最終更新日 2021-08-11 実験手法 ELECTRON MICROSCOPY (2.69 Å) 主引用文献 Structural basis of early translocation events on the ribosome. Nature, 595, 2021
8BF9	Molecular view of ER membrane remodeling by the Sec61/TRAP translocon. 分子名称: 60S ribosomal protein L39, Large ribosomal subunit protein eL31, Large ribosomal subunit protein eL38, ... 著者 Karki, S, Javanainen, M, Tranter, D, Rehan, S, Huiskonen, J, Happonen, L, Paavilainen, V. 登録日 2022-10-24 公開日 2023-11-01 最終更新日 2023-12-20 実験手法 ELECTRON MICROSCOPY (2.69 Å) 主引用文献 Molecular view of ER membrane remodeling by the Sec61/TRAP translocon. Embo Rep., 24, 2023
5AHU	T. Brucei Farnesyl Diphosphate Synthase Complexed with Bisphosphonate BPH-1326 分子名称: FARNESYL PYROPHOSPHATE SYNTHASE, PUTATIVE, MAGNESIUM ION, ... 著者 Yang, G, Oldfield, E, No, J.H. 登録日 2015-02-09 公開日 2015-10-28 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.69 Å) 主引用文献 Inhibition of Trypanosoma Brucei Cell Growth by Lipophilic Bisphosphonates: An in Vitro and in Vivo Investigation. Antimicrob.Agents Chemother., 59, 2015
7ZCI	Complex I from E. coli, LMNG-purified, under Turnover at pH 6, Resting state 分子名称: 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, CALCIUM ION, ... 著者 Kravchuk, V, Kampjut, D, Sazanov, L. 登録日 2022-03-28 公開日 2022-09-21 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (2.69 Å) 主引用文献 A universal coupling mechanism of respiratory complex I. Nature, 609, 2022
8RJB	Structure of the rabbit 80S ribosome stalled on a 2-TMD rhodopsin intermediate in complex with Sec61-RAMP4 分子名称: 28S rRNA, 5.8S rRNA, 5S rRNA, ... 著者 Lewis, A.J.O, Hegde, R.S. 登録日 2023-12-20 公開日 2024-01-24 最終更新日 2024-08-07 実験手法 ELECTRON MICROSCOPY (2.69243 Å) 主引用文献 Structural analysis of the dynamic ribosome-translocon complex. Elife, 13, 2024
5HNA	Crystal structure of Plasmodium vivax geranylgeranylpyrophosphate synthase complexed with BPH-1251 分子名称: 4-chloro-2-{[3-(decyloxy)-5-hydroxybenzyl]oxy}-5-sulfamoylbenzoic acid, Farnesyl pyrophosphate synthase, putative 著者 Liu, Y.-L, Zhang, Y, Oldfield, E. 登録日 2016-01-18 公開日 2016-09-07 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.693 Å) 主引用文献 Dynamic Structure and Inhibition of a Malaria Drug Target: Geranylgeranyl Diphosphate Synthase. Biochemistry, 55, 2016
2QN2	Glycogen Phosphorylase b in complex with Maslinic Acid 分子名称: Glycogen phosphorylase, muscle form, maslinic acid 著者 Zographos, S.E, Leonidas, D.D, Alexacou, K.-M, Hayes, J, Oikonomakos, N.G. 登録日 2007-07-17 公開日 2008-06-03 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.698 Å) 主引用文献 Naturally occurring pentacyclic triterpenes as inhibitors of glycogen phosphorylase: synthesis, structure-activity relationships, and X-ray crystallographic studies J.Med.Chem., 51, 2008
1QTY	VASCULAR ENDOTHELIAL GROWTH FACTOR IN COMPLEX WITH DOMAIN 2 OF THE FLT-1 RECEPTOR 分子名称: FMS-LIKE TYROSINE KINASE 1, VASCULAR ENDOTHELIAL GROWTH FACTOR 著者 Wiesmann, C, de Vos, A.M. 登録日 1999-06-29 公開日 2000-01-12 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Solution structure of the VEGF-binding domain of Flt-1: comparison of its free and bound states. J.Mol.Biol., 293, 1999
2AZK	Crystal structure for the mutant W136E of Sulfolobus solfataricus hexaprenyl pyrophosphate synthase 分子名称: Geranylgeranyl pyrophosphate synthetase 著者 Sun, H.Y, Ko, T.P, Kuo, C.J, Guo, R.T, Chou, C.C, Liang, P.H, Wang, A.H.J. 登録日 2005-09-12 公開日 2006-03-14 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Homodimeric hexaprenyl pyrophosphate synthase from the thermoacidophilic crenarchaeon Sulfolobus solfataricus displays asymmetric subunit structures J.Bacteriol., 187, 2005

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