PDB: 13422 件ウェブページステータス検索Chemie searchBIRD

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3DUH	Structure of Interleukin-23 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-12 subunit beta, Interleukin-23 subunit alpha 著者 Lupardus, P.J, Garcia, K.C. 登録日 2008-07-17 公開日 2008-08-19 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The structure of interleukin-23 reveals the molecular basis of p40 subunit sharing with interleukin-12. J.Mol.Biol., 382, 2008
5KIT	Crystal Structure of Nicotinamide Phosphoribosyltransferase (Nampt) in Complex with Inhibitors 37 分子名称: 1,2-ETHANEDIOL, Nicotinamide phosphoribosyltransferase, PHOSPHATE ION, ... 著者 Li, D, Wang, W. 登録日 2016-06-17 公開日 2016-08-31 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Minimizing CYP2C9 Inhibition of Exposed-Pyridine NAMPT (Nicotinamide Phosphoribosyltransferase) Inhibitors. J.Med.Chem., 59, 2016
5KPP	Structure of human PARP1 catalytic domain bound to a quinazoline-2,4(1H,3H)-dione inhibitor 分子名称: 1-[[4-fluoranyl-3-[(3R)-3-methyl-4-[2,2,2-tris(fluoranyl)ethyl]piperazin-1-yl]carbonyl-phenyl]methyl]quinazoline-2,4-dione, Poly [ADP-ribose] polymerase 1 著者 Cao, R, Wang, Y.L, Zhou, J, Huang, N, Xu, B.L. 登録日 2016-07-05 公開日 2016-11-30 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.33 Å) 主引用文献 Structure of human PARP1 catalytic domain bound to a quinazoline-2,4(1H,3H)-dione inhibitor To Be Published
3ELO	Crystal Structure of Human Pancreatic Prophospholipase A2 分子名称: Phospholipase A2, SULFATE ION 著者 Xu, W, Yi, L, Feng, Y, Chen, L, Liu, J. 登録日 2008-09-22 公開日 2009-04-14 最終更新日 2014-02-05 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Structural insight into the activation mechanism of human pancreatic prophospholipase A2 J.Biol.Chem., 284, 2009
5KPM	Glycogen Synthase Kinase 3 beta Complexed with BRD3731 分子名称: (4~{S})-3-(2,2-dimethylpropyl)-4,7,7-trimethyl-4-phenyl-2,6,8,9-tetrahydropyrazolo[3,4-b]quinolin-5-one, Glycogen synthase kinase-3 beta 著者 Lakshminarasimhan, D, White, A, Nadupalli, A, Suto, R.K. 登録日 2016-07-04 公開日 2018-03-14 最終更新日 2018-03-21 実験手法 X-RAY DIFFRACTION (2.69 Å) 主引用文献 Exploiting an Asp-Glu "switch" in glycogen synthase kinase 3 to design paralog-selective inhibitors for use in acute myeloid leukemia. Sci Transl Med, 10, 2018
5KPL	Glycogen Synthase Kinase 3 beta Complexed with BRD0705 分子名称: (4~{S})-4-ethyl-7,7-dimethyl-4-phenyl-2,6,8,9-tetrahydropyrazolo[3,4-b]quinolin-5-one, Glycogen synthase kinase-3 beta 著者 Lakshminarasimhan, D, White, A, Nadupalli, A, Suto, R.K. 登録日 2016-07-04 公開日 2018-03-14 最終更新日 2018-03-21 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Exploiting an Asp-Glu "switch" in glycogen synthase kinase 3 to design paralog-selective inhibitors for use in acute myeloid leukemia. Sci Transl Med, 10, 2018
2V4O	Crystal structure of Salmonella typhimurium SurE at 2.75 angstrom resolution in monoclinic form 分子名称: GLYCEROL, MAGNESIUM ION, MULTIFUNCTIONAL PROTEIN SUR E, ... 著者 Anju, P, Savithri, H.S, Murthy, M.R.N. 登録日 2008-09-26 公開日 2008-12-09 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.71 Å) 主引用文献 Structural and Functional Studies on a Mesophilic Stationary Phase Survival Protein (Sur E) from Salmonella Typhimurium FEBS J., 275, 2008
3FVI	Crystal Structure of Complex of Phospholipase A2 with Octyl Sulfates 分子名称: CALCIUM ION, CHLORIDE ION, Phospholipase A2, ... 著者 Pan, Y.H. 登録日 2009-01-15 公開日 2010-03-16 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structure of a premicellar complex of alkyl sulfates with the interfacial binding surfaces of four subunits of phospholipase A2. Biochim.Biophys.Acta, 1804, 2010
5KPK	Glycogen Synthase Kinase 3 beta Complexed with BRD0209 分子名称: (4~{S})-3-cyclopropyl-4,7,7-trimethyl-4-phenyl-2,6,8,9-tetrahydropyrazolo[3,4-b]quinolin-5-one, Glycogen synthase kinase-3 beta 著者 Lakshminarasimhan, D, White, A, Nadupalli, A, Suto, R.K. 登録日 2016-07-04 公開日 2018-03-14 最終更新日 2018-03-21 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Exploiting an Asp-Glu "switch" in glycogen synthase kinase 3 to design paralog-selective inhibitors for use in acute myeloid leukemia. Sci Transl Med, 10, 2018
5KPO	Structure of human PARP1 catalytic domain bound to a quinazoline-2,4(1H,3H)-dione inhibitor 分子名称: 1-[[3-(4-ethyl-3-oxidanylidene-piperazin-1-yl)carbonyl-4-fluoranyl-phenyl]methyl]quinazoline-2,4-dione, Poly [ADP-ribose] polymerase 1 著者 Cao, R, Wang, Y.L, Zhou, J, Yao, H.P, Huang, N, Xu, B.L. 登録日 2016-07-05 公開日 2016-12-21 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Structure of human PARP1 catalytic domain bound to a quinazoline-2,4(1H,3H)-dione inhibitor To Be Published
3FVJ	Crystal structure of phospholipase A2 1B crystallized in the presence of octyl sulfate 分子名称: CALCIUM ION, CHLORIDE ION, Phospholipase A2, ... 著者 Pan, Y.H. 登録日 2009-01-15 公開日 2010-03-16 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure of a premicellar complex of alkyl sulfates with the interfacial binding surfaces of four subunits of phospholipase A2. Biochim.Biophys.Acta, 1804, 2010
3G6D	Crystal structure of the complex between CNTO607 Fab and IL-13 分子名称: CNTO607 Fab Heavy chain, CNTO607 Fab Light chain, Interleukin-13, ... 著者 Teplyakov, A, Obmolova, G, Gilliland, G.L. 登録日 2009-02-06 公開日 2009-04-07 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Epitope mapping of anti-interleukin-13 neutralizing antibody CNTO607. J.Mol.Biol., 389, 2009
1VRL	MutY adenine glycosylase in complex with DNA and soaked adenine free base 分子名称: 5'-D(*AP*AP*GP*AP*CP*(8OG)P*TP*GP*GP*AP*C)-3', 5'-D(*TP*GP*TP*CP*CP*AP*(HPD)P*GP*TP*CP*T)-3', ADENINE, ... 著者 Fromme, J.C, Banerjee, A, Huang, S.J, Verdine, G.L. 登録日 2005-03-08 公開日 2005-03-22 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural basis for removal of adenine mispaired with 8-oxoguanine by MutY adenine DNA glycosylase Nature, 427, 2004
7ACK	CDK2/cyclin A2 in complex with an imidazo[1,2-c]pyrimidin-5-one inhibitor 分子名称: 1,2-ETHANEDIOL, 8-cyclohexyl-6~{H}-imidazo[1,2-c]pyrimidin-5-one, Cyclin-A2, ... 著者 Skerlova, J, Pachl, P, Rezacova, P. 登録日 2020-09-11 公開日 2021-03-24 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Imidazo[1,2-c]pyrimidin-5(6H)-one inhibitors of CDK2: Synthesis, kinase inhibition and co-crystal structure. Eur.J.Med.Chem., 216, 2021
3LKX	Human nac dimerization domain 分子名称: Nascent polypeptide-associated complex subunit alpha, Transcription factor BTF3 著者 Liu, Y, Hu, Y, Li, X, Niu, L, Teng, M. 登録日 2010-01-28 公開日 2010-03-23 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The crystal structure of the human nascent polypeptide-associated complex domain reveals a nucleic acid-binding region on the NACA subunit Biochemistry, 49, 2010
5XV8	Solution structure of the complex between UVSSA acidic region and TFIIH p62 PH domain 分子名称: General transcription factor IIH subunit 1, UV-stimulated scaffold protein A 著者 Okuda, M, Nishimura, Y. 登録日 2017-06-27 公開日 2017-11-08 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Common TFIIH recruitment mechanism in global genome and transcription-coupled repair subpathways Nucleic Acids Res., 45, 2017
3LFN	Crystal structure of CDK2 with SAR57, an aminoindazole type inhibitor 分子名称: Cell division protein kinase 2, N-[6-(4-hydroxyphenyl)-5-phenyl-1H-indazol-3-yl]butanamide 著者 Dreyer, M.K, Wendt, K.U, Schimanski-Breves, S, Loenze, P. 登録日 2010-01-18 公開日 2010-03-02 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Rational design of potent GSK3beta inhibitors with selectivity for Cdk1 and Cdk2. Bioorg.Med.Chem.Lett., 20, 2010
6ZVC	14-3-3 Sigma in complex with phosphorylated Gab2pT391 peptide - 48h incubation 分子名称: 14-3-3 protein sigma, MAGNESIUM ION, phosphorylated Gab2pT391 peptide 著者 Ballone, A, Lau, R.A, Zweipfenning, F.P.A, Ottmann, C. 登録日 2020-07-24 公開日 2021-08-04 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.51 Å) 主引用文献 A new soaking procedure for X-ray crystallography structural determination of protein-peptide complexes To Be Published
6ZVB	14-3-3 Sigma in complex with phosphorylated Gab2pT391 peptide - 24h incubation 分子名称: 14-3-3 protein sigma, MAGNESIUM ION, phosphorylated Gab2pT391 peptide 著者 Ballone, A, Lau, R.A, Zweipfenning, F.P.A, Ottmann, C. 登録日 2020-07-24 公開日 2021-08-04 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.51 Å) 主引用文献 A new soaking procedure for X-ray crystallography structural determination of protein-peptide complexes To Be Published
6ZVD	14-3-3 Sigma in complex with phosphorylated Gab2pT391 peptide - 96h incubation 分子名称: 14-3-3 protein sigma, MAGNESIUM ION, phosphorylated Gab2pT391 peptide 著者 Ballone, A, Lau, R.A, Zweipfenning, F.P.A, Ottmann, C. 登録日 2020-07-24 公開日 2021-08-04 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 A new soaking procedure for X-ray crystallography structural determination of protein-peptide complexes To Be Published
6ZVE	14-3-3 Sigma in complex with phosphorylated Gab2pT391 peptide - 1h incubation 分子名称: 14-3-3 protein sigma, MAGNESIUM ION, phosphorylated Gab2pT391 peptide 著者 Ballone, A, Lau, R.A, Zweipfenning, F.P.A, Ottmann, C. 登録日 2020-07-24 公開日 2021-08-04 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.51 Å) 主引用文献 A new soaking procedure for X-ray crystallography structural determination of protein-peptide complexes To Be Published
5X6U	Crystal structure of human heteropentameric complex 分子名称: Ragulator complex protein LAMTOR1, Ragulator complex protein LAMTOR2, Ragulator complex protein LAMTOR3, ... 著者 Yonehara, R, Nada, S, Nakai, T, Nakai, M, Kitamura, A, Ogawa, A, Nakatsumi, H, Nakayama, K.I, Li, S, Standley, D.M, Yamashita, E, Nakagawa, A, Okada, M. 登録日 2017-02-23 公開日 2017-12-06 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural basis for the assembly of the Ragulator-Rag GTPase complex. Nat Commun, 8, 2017
3LE6	The structure of cyclin dependent kinase 2 (CKD2) with a pyrazolobenzodiazepine inhibitor 分子名称: 5-(2-chlorophenyl)-3-methyl-7-nitropyrazolo[3,4-b][1,4]benzodiazepine, Cell division protein kinase 2 著者 Lukacs, C.M, Swain, A, Crowther, R.L, Kammlott, R.U, Liu, J.J. 登録日 2010-01-14 公開日 2010-11-17 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Pyrazolobenzodiazepines: part I. Synthesis and SAR of a potent class of kinase inhibitors. Bioorg.Med.Chem.Lett., 20, 2010
3LW1	Binary complex of 14-3-3 sigma and p53 pT387-peptide 分子名称: 14-3-3 protein sigma, CHLORIDE ION, GLYCEROL, ... 著者 Schumacher, B, Mondry, J, Thiel, P, Weyand, M, Ottmann, C. 登録日 2010-02-23 公開日 2010-03-23 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.28 Å) 主引用文献 Structure of the p53 C-terminus bound to 14-3-3: Implications for stabilization of the p53 tetramer Febs Lett., 584, 2010
5Y38	Crystal structure of C7orf59-HBXIP complex 分子名称: Ragulator complex protein LAMTOR4, Ragulator complex protein LAMTOR5, SULFATE ION 著者 Zhang, T, Ding, J. 登録日 2017-07-28 公開日 2017-12-06 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural basis for Ragulator functioning as a scaffold in membrane-anchoring of Rag GTPases and mTORC1 Nat Commun, 8, 2017

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