PDB: 66507 件ウェブページステータス検索Chemie searchBIRD

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2GHI	Crystal Structure of Plasmodium yoelii Multidrug Resistance Protein 2 分子名称: SULFATE ION, transport protein 著者 Dong, A, Gao, M, Choe, J, Zhao, Y, Lew, J, Wasney, G, Alam, Z, Melone, M, Kozieradzki, I, Vedadi, M, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Bochkarev, A, Hui, R, Artz, J.D, Structural Genomics Consortium (SGC) 登録日 2006-03-27 公開日 2006-04-25 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms. Mol.Biochem.Parasitol., 151, 2007
5ZR3	Crystal structure of Hsp90-alpha N-terminal domain in complex with 4-(3-isopropyl-4-(4-(1-methyl-1H-pyrazol-4-yl)-1H-imidazol-1-yl)-1H-pyrazolo[3,4-b]pyridin-1-yl)-3-methylbenzamide 分子名称: 3-methyl-4-{4-[4-(1-methyl-1H-pyrazol-4-yl)-1H-imidazol-1-yl]-3-(propan-2-yl)-1H-pyrazolo[3,4-b]pyridin-1-yl}benzamide, Heat shock protein HSP 90-alpha 著者 Uno, T, Chong, K.T, Suzuki, T. 登録日 2018-04-23 公開日 2019-01-02 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Discovery of 3-Ethyl-4-(3-isopropyl-4-(4-(1-methyl-1 H-pyrazol-4-yl)-1 H-imidazol-1-yl)-1 H-pyrazolo[3,4- b]pyridin-1-yl)benzamide (TAS-116) as a Potent, Selective, and Orally Available HSP90 Inhibitor. J. Med. Chem., 62, 2019
4ZNJ	Thermus Phage P74-26 Large Terminase ATPase domain mutant R139A (I 2 3 space group) 分子名称: Phage terminase large subunit, SULFATE ION 著者 Hilbert, B.J, Hayes, J.A, Stone, N.P, Duffy, C.M, Kelch, B.A. 登録日 2015-05-04 公開日 2015-07-08 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.532 Å) 主引用文献 Structure and mechanism of the ATPase that powers viral genome packaging. Proc.Natl.Acad.Sci.USA, 112, 2015
5ZYI	Crystal structure of CERT START domain in complex with compound E16 分子名称: 2-[4-[4-pentyl-3-[(1~{S},2~{R})-2-pyridin-2-ylcyclopropyl]phenyl]phenyl]sulfonylethanol, LIPID-TRANSFER PROTEIN CERT 著者 Suzuki, M, Nakao, N, Ueno, M, Sakai, S, Egawa, D, Hanzawa, H, Kawasaki, S, Kumagai, K, Kobayashi, S, Hanada, K. 登録日 2018-05-25 公開日 2019-02-27 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Natural ligand-nonmimetic inhibitors of the lipid-transfer protein CERT Commun Chem, 2019
5DJL	Structure of WT Human Glutathione Transferase in complex with cisplatin in the presence of glutathione. 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, CARBONATE ION, ... 著者 Parker, L.J. 登録日 2015-09-02 公開日 2016-11-02 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A structure-based mechanism of cisplatin resistance mediated by Glutathione Transferase P1-1 Proc.Natl.Acad.Sci.USA, 2019
7Z6E	Structure of the C1-PH-CNH regulatory module of MRCK1 分子名称: Serine/threonine-protein kinase mrck-1, ZINC ION 著者 Truebestein, L, Leonard, T.A. 登録日 2022-03-11 公開日 2023-02-22 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Structure and regulation of the myotonic dystrophy kinase-related Cdc42-binding kinase. Structure, 31, 2023
4ZBW	Crystal structure of death effector domain of Caspase8 in Homo Sapiens 分子名称: Caspase-8 著者 Shen, C, Wang, T, Quan, J. 登録日 2015-04-15 公開日 2015-07-01 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of the death effector domains of caspase-8 Biochem.Biophys.Res.Commun., 463, 2015
5ZYJ	Crystal structure of CERT START domain in complex with compound E16A 分子名称: 2-[4-[4-pentyl-3-[(1~{S},2~{R})-2-pyridin-2-ylcyclopropyl]phenyl]phenyl]sulfonylethanol, GLYCEROL, LIPID-TRANSFER PROTEIN CERT 著者 Suzuki, M, Nakao, N, Ueno, M, Sakai, S, Egawa, D, Hanzawa, H, Kawasaki, S, Kumagai, K, Kobayashi, S, Hanada, K. 登録日 2018-05-25 公開日 2019-02-27 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Natural ligand-nonmimetic inhibitors of the lipid-transfer protein CERT Commun Chem, 2019
6ZR8	The crystal structure of 2-(4-Benzhydrylpiperazin-1-yl)-N-(4-sulfamoylphenyl)acetamide in complex with human carbonic anhydrase II 分子名称: 2-[4-(diphenylmethyl)piperazin-1-yl]-~{N}-(4-sulfamoylphenyl)ethanamide, Carbonic anhydrase 2, ZINC ION 著者 Di Fiore, A, De Simone, G, D'Ambrosio, K. 登録日 2020-07-11 公開日 2021-06-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 The crystal structures of 2-(4-benzhydrylpiperazin-1-yl)-N-(4-sulfamoylphenyl)acetamide in complex with human carbonic anhydrase II and VII provide insights into selective CA inhibitor development New J.Chem., 45, 2021
6ZR9	The crystal structure of the complex of hCAVII with 2-(4-benzhydrylpiperazin-1-yl)-N-(4-sulfamoylphenyl)acetamide 分子名称: 2-[4-(diphenylmethyl)piperazin-1-yl]-~{N}-(4-sulfamoylphenyl)ethanamide, Carbonic anhydrase 7, ZINC ION 著者 D'Ambrosio, K, De Simone, G, Di Fiore, A. 登録日 2020-07-11 公開日 2021-06-16 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 The crystal structures of 2-(4-benzhydrylpiperazin-1-yl)-N-(4-sulfamoylphenyl)acetamide in complex with human carbonic anhydrase II and VII provide insights into selective CA inhibitor development New J.Chem., 45, 2021
5DRR	Crystal structure of the Pseudomonas aeruginosa LpxC/LPC-058 complex 分子名称: 4-[4-(4-aminophenyl)buta-1,3-diyn-1-yl]-N-[(2S,3S)-4,4-difluoro-3-hydroxy-1-(hydroxyamino)-3-methyl-1-oxobutan-2-yl]benzamide, NITRATE ION, UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase, ... 著者 Lee, C.-J, Najeeb, J, Zhou, P. 登録日 2015-09-16 公開日 2016-03-09 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.59 Å) 主引用文献 Drug design from the cryptic inhibitor envelope. Nat Commun, 7, 2016
4ZL4	Plasmepsin V from Plasmodium vivax bound to a transition state mimetic (WEHI-842) 分子名称: (2R)-1-[(2R)-2-(2-methoxyethoxy)propoxy]propan-2-amine, 1,2-ETHANEDIOL, Aspartic protease PM5, ... 著者 Czabotar, P.E, Hodder, A.N, Smith, B.J, Sleebs, B.E, Gazdic, M, Boddey, J.A, Cowman, A.F. 登録日 2015-05-01 公開日 2015-07-15 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.37 Å) 主引用文献 Structural basis for plasmepsin V inhibition that blocks export of malaria proteins to human erythrocytes. Nat.Struct.Mol.Biol., 22, 2015
5DSA	Crystal structure of Holliday junctions stabilized by 5-methylcytosine in GCC junction core 分子名称: 5'-D(*CP*CP*GP*GP*CP*GP*5CMP*CP*GP*G)-3', CALCIUM ION 著者 Vander Zanden, C.M, Ho, P.S. 登録日 2015-09-17 公開日 2016-09-28 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.6896 Å) 主引用文献 Effect of Hydroxymethylcytosine on the Structure and Stability of Holliday Junctions. Biochemistry, 55, 2016
6A3L	Crystal structure of cytochrome c' from Shewanella violacea DSS12 分子名称: Cytochrome c, HEME C 著者 Suka, A, Oki, H, Kato, Y, Kawahara, K, Ohkubo, T, Maruno, T, Kobayashi, Y, Fujii, S, Wakai, S, Sambongi, Y. 登録日 2018-06-15 公開日 2019-06-12 最終更新日 2019-10-02 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Stability of cytochromes c' from psychrophilic and piezophilic Shewanella species: implications for complex multiple adaptation to low temperature and high hydrostatic pressure. Extremophiles, 23, 2019
5DT9	Crystal structure of a putative D-Erythronate-4-Phosphate Dehydrogenase from Vibrio cholerae 分子名称: CHLORIDE ION, Erythronate-4-phosphate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... 著者 Stogios, P.J, Skarina, T, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2015-09-17 公開日 2015-09-30 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.663 Å) 主引用文献 Crystal structure of a putative D-Erythronate-4-Phosphate Dehydrogenase from Vibrio cholerae To Be Published
4ZR8	Structure of uroporphyrinogen decarboxylase from Acinetobacter baumannii 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, MAGNESIUM ION, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2015-05-11 公開日 2015-06-03 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structure of uroporphyrinogen decarboxylase from Acinetobacter baumannii To be Published
5ZVC	P domain of GII.13 norovirus capsid complexed with Lewis A trisaccharide 分子名称: GLYCEROL, Major capsid protein VP1, beta-D-galactopyranose-(1-3)-[alpha-L-fucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose 著者 Chen, Y, Li, X. 登録日 2018-05-10 公開日 2018-10-03 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural Adaptations of Norovirus GII.17/13/21 Lineage through Two Distinct Evolutionary Paths. J. Virol., 93, 2019
4WF6	Anthrax toxin lethal factor with bound small molecule inhibitor MK-31 分子名称: 1,2-ETHANEDIOL, Lethal factor, N~2~-[(4-fluoro-3-methylphenyl)sulfonyl]-N-hydroxy-D-alaninamide, ... 著者 Maize, K.M, De la Mora-Rey, T, Finzel, B.C. 登録日 2014-09-12 公開日 2015-09-09 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.6521 Å) 主引用文献 Probing the S2' Subsite of the Anthrax Toxin Lethal Factor Using Novel N-Alkylated Hydroxamates. J.Med.Chem., 58, 2015
6A4P	HEWL crystals soaked in 2.5M GuHCl for 40 minutes 分子名称: CHLORIDE ION, GUANIDINE, Lysozyme C, ... 著者 Tushar, R, Kini, R.M, Koh, C.Y, Hosur, M.V. 登録日 2018-06-20 公開日 2019-03-13 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 X-ray crystallographic analysis of time-dependent binding of guanidine hydrochloride to HEWL: First steps during protein unfolding. Int. J. Biol. Macromol., 122, 2019
5ZV9	P domain of GII.13 norovirus capsid 分子名称: GLYCEROL, Major capsid protein VP1 著者 Chen, Y, Li, X. 登録日 2018-05-09 公開日 2018-10-03 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural Adaptations of Norovirus GII.17/13/21 Lineage through Two Distinct Evolutionary Paths. J. Virol., 93, 2019
5DSB	Crystal structure of Holliday junctions stabilized by 5-hydroxymethylcytosine in GCC junction core 分子名称: 5'-D(*CP*CP*GP*GP*CP*GP*5HCP*CP*GP*G)-3', CALCIUM ION 著者 Vander Zanden, C.M, Rowe, R.K, Broad, A.J, Ho, P.S. 登録日 2015-09-17 公開日 2016-09-28 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.4959 Å) 主引用文献 Effect of Hydroxymethylcytosine on the Structure and Stability of Holliday Junctions. Biochemistry, 55, 2016
5DRI	Crystal structure of Mycobacterium tuberculosis malate synthase in complex with 2-hydroxy-4-(1H-indol-5-yl)-4-oxobut-2-enoic acid inhibitor 分子名称: (2Z)-2-hydroxy-4-(1H-indol-5-yl)-4-oxobut-2-enoic acid, MAGNESIUM ION, Malate synthase G 著者 Krieger, I.V, Huang, H.-L, Sacchettini, J.C. 登録日 2015-09-15 公開日 2016-09-28 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Mycobacterium tuberculosis Malate Synthase Structures with Fragments Reveal a Portal for Substrate/Product Exchange. J. Biol. Chem., 291, 2016
7AA4	Structure of ClpC1-NTD bound to a CymA analogue 分子名称: Negative regulator of genetic competence ClpC/mecB, polymer Cyclomarin A analogue 著者 Meinhart, A, Morreale, F.E, Kaiser, M, Clausen, T. 登録日 2020-09-03 公開日 2021-08-11 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 BacPROTACs mediate targeted protein degradation in bacteria. Cell, 185, 2022
4WOC	Proteinase-K Post-Surface Acoustic Waves 分子名称: Proteinase K, SULFATE ION 著者 French, J.B. 登録日 2014-10-15 公開日 2015-02-18 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.601 Å) 主引用文献 Precise Manipulation and Patterning of Protein Crystals for Macromolecular Crystallography Using Surface Acoustic Waves. Small, 11, 2015
5ZY8	Crystal structure of C terminal truncated HadBC (3R-Hydroxyacyl-ACP Dehydratase) complex from Mycobacterium tuberculosis 分子名称: 3-hydroxyacyl-ACP dehydratase, UPF0336 protein Rv0637 著者 Singh, B.K, Biswas, R, Bhattacharyya, S, Basak, A, Das, A.K. 登録日 2018-05-23 公開日 2019-06-12 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.899 Å) 主引用文献 The C-terminal end of mycobacterial HadBC regulates AcpM interaction during the FAS-II pathway: a structural perspective. Febs J., 2022

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