PDB: 45176 件ウェブページステータス検索Chemie searchBIRD

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1GHY	A NOVEL SERINE PROTEASE INHIBITION MOTIF INVOLVING A MULTI-CENTERED SHORT HYDROGEN BONDING NETWORK AT THE ACTIVE SITE 分子名称: 2-(3-HYDROXY-PYRIDIN-2-YL)-1H-BENZOIMIDAZOLE-5-CARBOXAMIDINE, ACETYL HIRUDIN, CALCIUM ION, ... 著者 Katz, B.A, Elrod, K, Luong, C, Rice, M, Mackman, R.L, Sprengeler, P.A, Spencer, J, Hatayte, J, Janc, J, Link, J, Litvak, J, Rai, R, Rice, K, Sideris, S, Verner, E, Young, W. 登録日 2001-01-22 公開日 2002-01-22 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 A novel serine protease inhibition motif involving a multi-centered short hydrogen bonding network at the active site. J.Mol.Biol., 307, 2001
1GE4	CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT LEFT-HANDED HELICAL POSITIONS 分子名称: LYSOZYME C, SODIUM ION 著者 Takano, K, Yamagata, Y, Yutani, K. 登録日 2000-10-06 公開日 2000-11-08 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Role of non-glycine residues in left-handed helical conformation for the conformational stability of human lysozyme Proteins, 44, 2001
1XKN	Crystal Structure of the Putative Peptidyl-arginine Deiminase from Chlorobium tepidum, NESG Target CtR21 分子名称: CHLORIDE ION, SODIUM ION, putative peptidyl-arginine deiminase 著者 Forouhar, F, Befeler, A.R, Vorobiev, S.M, Hussain, M, Ciano, M, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) 登録日 2004-09-29 公開日 2004-11-16 最終更新日 2017-10-11 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal Structure of the Putative Peptidyl-arginine Deiminase from Chlorobium tepidum, NESG Target CtR21 To be Published
1GFG	CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS 分子名称: LYSOZYME, SODIUM ION 著者 Funahashi, J, Takano, K, Yamagata, Y, Yutani, K. 登録日 2000-12-04 公開日 2000-12-20 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Positive contribution of hydration structure on the surface of human lysozyme to the conformational stability. J.Biol.Chem., 277, 2002
1GFR	CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS 分子名称: LYSOZYME, SODIUM ION 著者 Funahashi, J, Takano, K, Yamagata, Y, Yutani, K. 登録日 2000-12-04 公開日 2000-12-27 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Positive contribution of hydration structure on the surface of human lysozyme to the conformational stability. J.Biol.Chem., 277, 2002
1GHW	A NOVEL SERINE PROTEASE INHIBITION MOTIF INVOLVING A MULTI-CENTERED SHORT HYDROGEN BONDING NETWORK AT THE ACTIVE SITE 分子名称: 2-(2-HYDROXY-PHENYL)-1H-BENZOIMIDAZOLE-5-CARBOXAMIDINE, ACETYL HIRUDIN, SODIUM ION, ... 著者 Katz, B.A, Elrod, K, Luong, C, Rice, M, Mackman, R.L, Sprengeler, P.A, Spencer, J, Hatayte, J, Janc, J, Link, J, Litvak, J, Rai, R, Rice, K, Sideris, S, Verner, E, Young, W. 登録日 2001-01-22 公開日 2002-01-22 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 A novel serine protease inhibition motif involving a multi-centered short hydrogen bonding network at the active site J.Mol.Biol., 307, 2001
7XKA	Structure of human beta2 adrenergic receptor bound to constrained epinephrine 分子名称: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Camelid Antibody Fragment, Endolysin,Beta-2 adrenergic receptor, ... 著者 Xu, X, Shonberg, J, Kaindl, J, Clark, M, Stobel, A, Maul, L, Mayer, D, Hubner, H, Venkatakrishnan, A, Dror, R, Kobilka, B.K, Sunahara, R, Liu, X, Gmeiner, P. 登録日 2022-04-19 公開日 2023-04-26 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Constrained catecholamines gain beta 2 AR selectivity through allosteric effects on pocket dynamics. Nat Commun, 14, 2023
1GN0	Escherichia coli GlpE sulfurtransferase soaked with KCN 分子名称: 1,2-ETHANEDIOL, SODIUM ION, THIOSULFATE SULFURTRANSFERASE GLPE 著者 Spallarossa, A, Donahue, J.T, Larson, T.J, Bolognesi, M, Bordo, D. 登録日 2001-10-01 公開日 2001-11-29 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Escherichia Coli Glpe is a Prototype Sulfurtransferase for the Single-Domain Rhodanese Homology Superfamily Structure, 9, 2001
1GJ5	SELECTIVITY AT S1, H2O DISPLACEMENT, UPA, TPA, SER190/ALA190 PROTEASE, STRUCTURE-BASED DRUG DESIGN 分子名称: 2-(2-HYDROXY-BIPHENYL)-1H-BENZOIMIDAZOLE-5-CARBOXAMIDINE, ACETYL HIRUDIN, SODIUM ION, ... 著者 Katz, B.A, Sprengeler, P.A, Luong, C, Verner, E, Spencer, J.R, Breitenbucher, J.G, Hui, H, McGee, D, Allen, D, Martelli, A, Mackman, R.L. 登録日 2001-04-27 公開日 2002-04-27 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Engineering inhibitors highly selective for the S1 sites of Ser190 trypsin-like serine protease drug targets. Chem.Biol., 8, 2001
7LK8	Crystal structure of KPC-2 T215P mutant 分子名称: Beta-lactamase, SODIUM ION 著者 Furey, I, Palzkill, T, Sankaran, B, Hu, L, Prasad, B.V.V. 登録日 2021-02-01 公開日 2021-05-26 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.43 Å) 主引用文献 Local interactions with the Glu166 base and the conformation of an active site loop play key roles in carbapenem hydrolysis by the KPC-2 beta-lactamase. J.Biol.Chem., 296, 2021
1D3Y	STRUCTURE OF THE DNA TOPOISOMERASE VI A SUBUNIT 分子名称: DNA TOPOISOMERASE VI A SUBUNIT, MAGNESIUM ION, SODIUM ION 著者 Nichols, M.D, DeAngelis, K.A, Keck, J.L, Berger, J.M. 登録日 1999-10-01 公開日 1999-11-05 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure and function of an archaeal topoisomerase VI subunit with homology to the meiotic recombination factor Spo11. EMBO J., 18, 1999
1GLH	CATION BINDING TO A BACILLUS (1,3-1,4)-BETA-GLUCANASE. GEOMETRY, AFFINITY AND EFFECT ON PROTEIN STABILITY 分子名称: 1,3-1,4-BETA-GLUCANASE, SODIUM ION 著者 Keitel, T, Heinemann, U. 登録日 1994-11-25 公開日 1995-02-07 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Cation binding to a Bacillus (1,3-1,4)-beta-glucanase. Geometry, affinity and effect on protein stability Eur.J.Biochem., 222, 1994
7MFP	crystal structure of the L136 aminotransferase K185A from acanthamoeba polyphaga mimivirus in the presence of the UDP-viosamine external aldimine 分子名称: (2R,3R,4S,5S,6R)-3,4-dihydroxy-5-[(E)-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)amino]-6-methyloxan-2-yl [(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen diphosphate (non-preferred name), 1,2-ETHANEDIOL, CHLORIDE ION, ... 著者 Seltzner, C.A, Thoden, J.B, Holden, H.M. 登録日 2021-04-10 公開日 2021-04-28 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Characterization of an aminotransferase from Acanthamoeba polyphaga Mimivirus. Protein Sci., 30, 2021
7MFQ	crystal structure of the L136 aminotransferase from acanthamoeba polyphaga mimivirus in complex with the TDP-viosamine external aldimine 分子名称: (2R,3R,4S,5S,6R)-3,4-DIHYDROXY-5-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)IMINO]-6-METHYLTETRAHYDRO-2H-PYRAN-2-YL [(2R,3S,5R)-3-HYDROXY-5-(5-METHYL-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)TETRAHYDROFURAN-2-YL]METHYL DIHYDROGEN DIPHOSPHATE, 1,2-ETHANEDIOL, CHLORIDE ION, ... 著者 Seltzner, C.A, Thoden, J.B, Holden, H.M. 登録日 2021-04-10 公開日 2021-04-28 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Characterization of an aminotransferase from Acanthamoeba polyphaga Mimivirus. Protein Sci., 30, 2021
1GNY	xylan-binding module CBM15 分子名称: SODIUM ION, XYLANASE 10C, beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose 著者 Szabo, S, Jamal, S, Xie, H, Charnock, S.J, Bolam, D.N, Gilbert, H.J, Davies, G.J. 登録日 2001-10-10 公開日 2001-11-29 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 Structure of a Family 15 Carbohydrate-Binding Module in Complex with Xylopentaose: Evidence that Xylan Binds in an Approximate Three-Fold Helical Conformation J.Biol.Chem., 276, 2001
7ML9	The Mpp75Aa1.1 beta-pore-forming protein from Brevibacillus laterosporus 分子名称: 1,2-ETHANEDIOL, ACETATE ION, Insecticidal protein, ... 著者 Rydel, T.J, Zheng, M, Evdokimov, A. 登録日 2021-04-27 公開日 2021-05-05 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Structural and functional characterization of Mpp75Aa1.1, a putative beta-pore forming protein from Brevibacillus laterosporus active against the western corn rootworm. Plos One, 16, 2021
7M3Q	Structure of the Smurf2 HECT Domain with a High Affinity Ubiquitin Variant (UbV) 分子名称: 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, CHLORIDE ION, ... 著者 Chowdhury, A, Singer, A.U, Ogunjimi, A.A, Teyra, J, Zhang, W, Sicheri, F, Sidhu, S.S. 登録日 2021-03-18 公開日 2021-04-21 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure of the Smurf2 HECT Domain with a High Affinity Ubiquitin Variant (UbV) To be published
1ZL0	Structure of Protein of Unknown Function PA5198 from Pseudomonas aeruginosa 分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... 著者 Osipiuk, J, Evdokimova, E, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2005-05-04 公開日 2005-06-21 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 X-ray crystal structure of hypothetical protein PA5198 at 1.1 A resolution. To be Published
7V9E	Crystal structure of a methyl transferase ribozyme 分子名称: BARIUM ION, GUANINE, RNA (68-MER), ... 著者 Deng, J, Lilley, D.M.J, Huang, L. 登録日 2021-08-25 公開日 2022-03-23 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure and mechanism of a methyltransferase ribozyme. Nat.Chem.Biol., 18, 2022
1ZOH	Crystal structure of protein kinase CK2 in complex with TBB-derivatives inhibitors 分子名称: 1,2-ETHANEDIOL, 5,6,7,8-TETRABROMO-1-METHYL-2,3-DIHYDRO-1H-IMIDAZO[1,2-A]BENZIMIDAZOLE, CHLORIDE ION, ... 著者 Battistutta, R, Mazzorana, M, Sarno, S, Kazimierczuk, Z, Zanotti, G, Pinna, L.A. 登録日 2005-05-13 公開日 2005-11-29 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 Inspecting the structure-activity relationship of protein kinase CK2 inhibitors derived from tetrabromo-benzimidazole. Chem.Biol., 12, 2005
1YVM	E. coli Methionine Aminopeptidase in complex with thiabendazole 分子名称: 2-(1,3-THIAZOL-4-YL)-1H-BENZIMIDAZOLE, COBALT (II) ION, Methionine aminopeptidase, ... 著者 Schiffmann, R, Heine, A, Klebe, G, Klein, C.D. 登録日 2005-02-16 公開日 2005-06-07 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Metal Ions as Cofactors for the Binding of Inhibitors to Methionine Aminopeptidase: A Critical View of the Relevance of In Vitro Metalloenzyme Assays. Angew.Chem.Int.Ed.Engl., 44, 2005
7VUK	Crystal Structure of the core region of Thermus thermophilus MutS2 complexed with ADP. 分子名称: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Fukui, K, Yano, T. 登録日 2021-11-02 公開日 2022-04-06 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.38 Å) 主引用文献 Structural and functional insights into the mechanism by which MutS2 recognizes a DNA junction. Structure, 30, 2022
3SAN	Crystal structure of influenza A virus neuraminidase N5 complexed with Zanamivir 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Wang, M.Y, Qi, J.X, Liu, Y, Vavricka, C.J, Wu, Y, Li, Q, Gao, G.F. 登録日 2011-06-03 公開日 2011-08-10 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Influenza a virus n5 neuraminidase has an extended 150-cavity J.Virol., 85, 2011
1Y3B	Crystal structure of the complex of subtilisin BPN' with chymotrypsin inhibitor 2 E60S mutant 分子名称: CALCIUM ION, CITRIC ACID, POLYETHYLENE GLYCOL (N=34), ... 著者 Radisky, E.S, Lu, C.J, Kwan, G, Koshland Jr, D.E. 登録日 2004-11-24 公開日 2005-05-17 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Role of the intramolecular hydrogen bond network in the inhibitory power of chymotrypsin inhibitor 2 Biochemistry, 44, 2005
1Y48	Crystal structure of the complex of subtilisin BPN' with chymotrypsin inhibitor 2 R65A mutant 分子名称: CALCIUM ION, CITRIC ACID, POLYETHYLENE GLYCOL (N=34), ... 著者 Radisky, E.S, Lu, C.J, Kwan, G, Koshland Jr, D.E. 登録日 2004-11-30 公開日 2005-05-17 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Role of the intramolecular hydrogen bond network in the inhibitory power of chymotrypsin inhibitor 2 Biochemistry, 44, 2005

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