PDB: 17012 件ウェブページステータス検索Chemie searchBIRD

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3KK7	Crystal structure of Putative cell invasion protein with MAC/Perforin domain (NP_812351.1) from BACTERIODES THETAIOTAOMICRON VPI-5482 at 2.46 A resolution 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, CHLORIDE ION, ... 著者 Joint Center for Structural Genomics (JCSG) 登録日 2009-11-04 公開日 2009-11-24 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (2.46 Å) 主引用文献 Structure of a membrane-attack complex/perforin (MACPF) family protein from the human gut symbiont Bacteroides thetaiotaomicron. Acta Crystallogr.,Sect.F, 66, 2010
1TN6	Protein Farnesyltransferase Complexed with a Rap2a Peptide Substrate and a FPP Analog at 1.8A Resolution 分子名称: ACETIC ACID, Protein farnesyltransferase alpha subunit, Protein farnesyltransferase beta subunit, ... 著者 Reid, T.S, Terry, K.L, Casey, P.J, Beese, L.S. 登録日 2004-06-11 公開日 2004-11-02 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystallographic analysis of CaaX prenyltransferases complexed with substrates defines rules of protein substrate selectivity J.Mol.Biol., 343, 2004
3KPW	Crystal Structure of hPNMT in Complex AdoHcy and 1-Aminoisoquinoline 分子名称: ISOQUINOLIN-1-AMINE, Phenylethanolamine N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE 著者 Drinkwater, N, Martin, J.L. 登録日 2009-11-17 公開日 2010-09-29 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Fragment-based screening by X-ray crystallography, MS and isothermal titration calorimetry to identify PNMT (phenylethanolamine N-methyltransferase) inhibitors. Biochem.J., 431, 2010
1DEU	CRYSTAL STRUCTURE OF HUMAN PROCATHEPSIN X: A CYSTEINE PROTEASE WITH THE PROREGION COVALENTLY LINKED TO THE ACTIVE SITE CYSTEINE 分子名称: PROCATHEPSIN X 著者 Sivaraman, J, Nagler, D.K, Zhang, R, Menard, R, Cygler, M. 登録日 1999-11-15 公開日 2000-02-18 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structure of human procathepsin X: a cysteine protease with the proregion covalently linked to the active site cysteine. J.Mol.Biol., 295, 2000
3KQP	Crystal Structure of hPNMT in Complex AdoHcy and 6-Aminoquinoline 分子名称: Phenylethanolamine N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, quinolin-6-amine 著者 Drinkwater, N, Martin, J.L. 登録日 2009-11-17 公開日 2010-09-29 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Fragment-based screening by X-ray crystallography, MS and isothermal titration calorimetry to identify PNMT (phenylethanolamine N-methyltransferase) inhibitors. Biochem.J., 431, 2010
1TPK	CRYSTAL STRUCTURE OF THE KRINGLE-2 DOMAIN OF TISSUE PLASMINOGEN ACTIVATOR AT 2.4-ANGSTROMS RESOLUTION 分子名称: CHLORIDE ION, TISSUE PLASMINOGEN ACTIVATOR 著者 De vos, A.M, Ultsch, M.H, Kelley, R.F, Padmanabhan, K, Tulinsky, A, Westbrook, M.L, Kossiakoff, A.A. 登録日 1991-09-24 公開日 1992-07-15 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of the kringle 2 domain of tissue plasminogen activator at 2.4-A resolution. Biochemistry, 31, 1992
3KTV	Crystal structure of the human SRP19/S-domain SRP RNA complex 分子名称: MAGNESIUM ION, POTASSIUM ION, SRP RNA, ... 著者 Wild, K, Bange, G, Bozkurt, G, Sinning, I. 登録日 2009-11-26 公開日 2010-02-16 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.8 Å) 主引用文献 Structural insights into the assembly of the human and archaeal signal recognition particles. Acta Crystallogr.,Sect.D, 66, 2010
3KQT	Crystal Structure of hPNMT in Complex AdoHcy and 2-Amino-1-methylbenzimidazole 分子名称: 1-methyl-1H-benzimidazol-2-amine, Phenylethanolamine N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE 著者 Drinkwater, N, Martin, J.L. 登録日 2009-11-17 公開日 2010-09-29 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.399 Å) 主引用文献 Fragment-based screening by X-ray crystallography, MS and isothermal titration calorimetry to identify PNMT (phenylethanolamine N-methyltransferase) inhibitors. Biochem.J., 431, 2010
1TQN	Crystal Structure of Human Microsomal P450 3A4 分子名称: PROTOPORPHYRIN IX CONTAINING FE, cytochrome P450 3A4 著者 Yano, J.K, Wester, M.R, Schoch, G.A, Griffin, K.J, Stout, C.D, Johnson, E.F. 登録日 2004-06-17 公開日 2004-07-27 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 The Structure of Human Microsomal Cytochrome P450 3A4 Determined by X-ray Crystallography to 2.05-A Resolution J.Biol.Chem., 279, 2004
1TQE	Mechanism of recruitment of class II histone deacetylases by myocyte enhancer factor-2 分子名称: Histone deacetylase 9, MEF2 binding site of nur77 promoter, Myocyte-specific enhancer factor 2B 著者 Chen, L, Han, A, He, J, Wu, Y, Liu, J.O. 登録日 2004-06-17 公開日 2004-12-21 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Mechanism of Recruitment of Class II Histone Deacetylases by Myocyte Enhancer Factor-2. J.Mol.Biol., 345, 2005
1DCQ	CRYSTAL STRUCTURE OF THE ARF-GAP DOMAIN AND ANKYRIN REPEATS OF PAPBETA. 分子名称: PYK2-ASSOCIATED PROTEIN BETA, ZINC ION 著者 Mandiyan, V, Andreev, J, Schlessinger, J, Hubbard, S.R. 登録日 1999-11-05 公開日 1999-12-22 最終更新日 2016-12-14 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of the ARF-GAP domain and ankyrin repeats of PYK2-associated protein beta. EMBO J., 18, 1999
1DCY	CRYSTAL STRUCTURE OF HUMAN S-PLA2 IN COMPLEX WITH INDOLE 3 ACTIVE SITE INHIBITOR 分子名称: 1-BENZYL-5-METHOXY-2-METHYL-1H-INDOL-3-YL)-ACETIC ACID, CALCIUM ION, PHOSPHOLIPASE A2 著者 Chirgadze, N.Y, Schevitz, R.W, Wery, J.-P. 登録日 1999-11-05 公開日 1999-11-12 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structure-based design of the first potent and selective inhibitor of human non-pancreatic secretory phospholipase A2. Nat.Struct.Biol., 2, 1995
5SZJ	Structure of human Rab10 in complex with the bMERB domain of Mical-cL 分子名称: DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, MICAL C-terminal-like protein, ... 著者 Rai, A, Oprisko, A, Campos, J, Fu, Y, Friese, T, Itzen, A, Goody, R.S, Mueller, M.P, Gazdag, E.M. 登録日 2016-08-14 公開日 2016-08-24 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.66 Å) 主引用文献 bMERB domains are bivalent Rab8 family effectors evolved by gene duplication. Elife, 5, 2016
3KYC	Human SUMO E1 complex with a SUMO1-AMP mimic 分子名称: 5'-deoxy-5'-(sulfamoylamino)adenosine, SUMO-activating enzyme subunit 1, SUMO-activating enzyme subunit 2, ... 著者 Lima, C.D. 登録日 2009-12-05 公開日 2010-02-16 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Active site remodelling accompanies thioester bond formation in the SUMO E1. Nature, 463, 2010
3KPU	Crystal Structure of hPNMT in Complex AdoHcy and 4-quinolinol 分子名称: Phenylethanolamine N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, quinolin-4-ol 著者 Drinkwater, N, Martin, J.L. 登録日 2009-11-17 公開日 2010-09-29 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Fragment-based screening by X-ray crystallography, MS and isothermal titration calorimetry to identify PNMT (phenylethanolamine N-methyltransferase) inhibitors. Biochem.J., 431, 2010
3KR0	Crystal Structure of hPNMT in Complex AdoHcy and 2-amino-1H-benzo[d]imidazol-6-ol 分子名称: 2-AMINO-5-HYDROXY-BENZIMIDAZOLE, Phenylethanolamine N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE 著者 Drinkwater, N, Martin, J.L. 登録日 2009-11-17 公開日 2010-09-29 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Fragment-based screening by X-ray crystallography, MS and isothermal titration calorimetry to identify PNMT (phenylethanolamine N-methyltransferase) inhibitors. Biochem.J., 431, 2010
3KRW	Human GRK2 in complex with Gbetgamma subunits and balanol (soak) 分子名称: BALANOL, Beta-adrenergic receptor kinase 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Tesmer, J.J.G, Tesmer, V.M. 登録日 2009-11-19 公開日 2010-02-16 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structure of human g protein-coupled receptor kinase 2 in complex with the kinase inhibitor balanol. J.Med.Chem., 53, 2010
5T3R	Crystal structure of BT1762-1763 分子名称: MAGNESIUM ION, SODIUM ION, SusC homolog, ... 著者 van den Berg, B. 登録日 2016-08-26 公開日 2016-12-14 最終更新日 2019-10-16 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structural basis for nutrient acquisition by dominant members of the human gut microbiota. Nature, 541, 2017
5T5G	human SETD8 in complex with MS2177 分子名称: 7-(2-aminoethoxy)-6-methoxy-2-(pyrrolidin-1-yl)-N-[5-(pyrrolidin-1-yl)pentyl]quinazolin-4-amine, N-lysine methyltransferase KMT5A, UNKNOWN ATOM OR ION 著者 Yu, W, Tempel, W, Babault, N, Ma, A, Butler, K.V, Jin, J, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Brown, P.J, Structural Genomics Consortium (SGC) 登録日 2016-08-30 公開日 2016-09-28 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure-Based Design of a Covalent Inhibitor of the SET Domain-Containing Protein 8 (SETD8) Lysine Methyltransferase. J. Med. Chem., 59, 2016
5SVO	Structure of IDH2 mutant R140Q 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Isocitrate dehydrogenase [NADP], mitochondrial, ... 著者 Xie, X, Kulathila, R. 登録日 2016-08-06 公開日 2017-02-08 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Allosteric Mutant IDH1 Inhibitors Reveal Mechanisms for IDH1 Mutant and Isoform Selectivity. Structure, 25, 2017
1UW5	Structure of PITP-alpha complexed to phosphatidylinositol 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOINOSITOL, PHOSPHATIDYLINOSITOL TRANSFER PROTEIN ALPHA ISOFORM 著者 Tilley, S.J, Skippen, A, Murray-Rust, J, Cockcroft, S, McDonald, N.Q. 登録日 2004-01-30 公開日 2004-03-04 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structure-Function Analysis of Human [Corrected] Phosphatidylinositol Transfer Protein Alpha Bound to Phosphatidylinositol. Structure, 12, 2004
1VA1	Solution Structure of Transcription Factor Sp1 DNA Binding Domain (Zinc Finger 1) 分子名称: Transcription factor Sp1, ZINC ION 著者 Oka, S, Shiraishi, Y, Yoshida, T, Ohkubo, T, Sugiura, Y, Kobayashi, Y. 登録日 2004-02-07 公開日 2005-02-08 最終更新日 2023-12-27 実験手法 SOLUTION NMR 主引用文献 NMR structure of transcription factor Sp1 DNA binding domain Biochemistry, 43, 2004
1DX9	W57A Apoflavodoxin from Anabaena 分子名称: Flavodoxin, SULFATE ION 著者 Romero, A, Sancho, J. 登録日 1999-12-23 公開日 2000-04-10 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Dissecting the Energetics of the Apoflavodoxin-Fmn Complex J.Biol.Chem., 275, 2000
1V49	Solution structure of microtubule-associated protein light chain-3 分子名称: Microtubule-associated proteins 1A/1B light chain 3B 著者 Kouno, T, Mizuguchi, M, Tanida, I, Ueno, T, Kominami, E, Kawano, K. 登録日 2003-11-11 公開日 2004-12-28 最終更新日 2023-12-27 実験手法 SOLUTION NMR 主引用文献 Solution structure of microtubule-associated protein light chain 3 and identification of its functional subdomains. J.Biol.Chem., 280, 2005
5VMW	Kaiso (ZBTB33) zinc finger DNA binding domain in complex with a double CpG-methylated DNA resembling the specific Kaiso binding sequence (KBS) 分子名称: CHLORIDE ION, DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*(5CM)P*GP*(5CM)P*GP*GP*GP*AP*AP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*TP*TP*CP*CP*(5CM)P*GP*(5CM)P*GP*AP*AP*TP*AP*AP*CP*G)-3'), ... 著者 Nikolova, E.N, Stanfield, R.L, Martinez-Yamout, M.A, Dyson, H.J, Wright, P.E. 登録日 2017-04-28 公開日 2018-04-04 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.397 Å) 主引用文献 CH···O Hydrogen Bonds Mediate Highly Specific Recognition of Methylated CpG Sites by the Zinc Finger Protein Kaiso. Biochemistry, 57, 2018

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