Human SUMO E1 complex with a SUMO1-AMP mimic

Summary for 3KYC

DescriptorSUMO-activating enzyme subunit 1, SUMO-activating enzyme subunit 2, Small ubiquitin-related modifier 1, ... (6 entities in total)
Functional Keywordse1, sumo, ubiquitin, thioester, adenylation, inhibitor, acyl-adenylate intermediate, acetylation, ligase, nucleus, phosphoprotein, ubl conjugation pathway, atp-binding, nucleotide-binding, polymorphism, cytoplasm, isopeptide bond, membrane
Biological sourceHomo sapiens (human)
Cellular locationNucleus  Q9UBE0
Cytoplasm Q9UBT2
Nucleus membrane P63165
Total number of polymer chains3
Total molecular weight123564.07
Lima, C.D. (deposition date: 2009-12-05, release date: 2010-02-16, Last modification date: 2017-11-01)
Primary citation
Olsen, S.K.,Capili, A.D.,Lu, X.,Tan, D.S.,Lima, C.D.
Active site remodelling accompanies thioester bond formation in the SUMO E1.
Nature, 463:906-912, 2010
PubMed: 20164921 (PDB entries with the same primary citation)
DOI: 10.1038/nature08765
MImport into Mendeley
Experimental method
NMR Information

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.253152.5%10.5%5.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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