3FD9
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6B40
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![BU of 6b40 by Molmil](/molmil-images/mine/6b40) | BbRAGL-3'TIR synaptic complex with nicked DNA refined with C2 symmetry | 分子名称: | 31TIR intact strand, 31TIR pre-nicked strand of flanking DNA, 31TIR pre-nicked strand of signal DNA, ... | 著者 | Zhang, Y, Cheng, T.C, Xiong, Y, Schatz, D.G. | 登録日 | 2017-09-25 | 公開日 | 2019-03-20 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Transposon molecular domestication and the evolution of the RAG recombinase. Nature, 569, 2019
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1U7B
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6EVU
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![BU of 6evu by Molmil](/molmil-images/mine/6evu) | Adhesin domain of PrgB from Enterococcus faecalis | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, PHOSPHATE ION, PrgB | 著者 | Schmitt, A, Berntsson, R.P.A. | 登録日 | 2017-11-02 | 公開日 | 2018-05-16 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.598 Å) | 主引用文献 | PrgB promotes aggregation, biofilm formation, and conjugation through DNA binding and compaction. Mol. Microbiol., 109, 2018
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2W4B
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![BU of 2w4b by Molmil](/molmil-images/mine/2w4b) | Epstein-Barr virus alkaline nuclease D203S mutant | 分子名称: | ALKALINE EXONUCLEASE | 著者 | Buisson, M, Geoui, T, Flot, D, Tarbouriech, N, Burmeister, W.P. | 登録日 | 2008-11-24 | 公開日 | 2009-06-30 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | A Bridge Crosses the Active Site Canyon of the Epstein-Barr Virus Nuclease with DNase and Rnase Activity. J.Mol.Biol., 391, 2009
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2MT3
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6NUD
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![BU of 6nud by Molmil](/molmil-images/mine/6nud) | Small conformation of ssRNA-bound CRISPR_Csm complex | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CRISPR system Cms protein Csm2, CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A), ... | 著者 | Zhang, K, Pintilie, G, Li, S, Zhu, Y, Chiu, W, Huang, Z. | 登録日 | 2019-01-31 | 公開日 | 2019-03-13 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Coupling of ssRNA cleavage with DNase activity in type III-A CRISPR-Csm revealed by cryo-EM and biochemistry. Cell Res., 29, 2019
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4DT1
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![BU of 4dt1 by Molmil](/molmil-images/mine/4dt1) | Crystal structure of the Psy3-Csm2 complex | 分子名称: | Chromosome segregation in meiosis protein 2, ETHANOL, Platinum sensitivity protein 3 | 著者 | Tao, Y, Niu, L, Teng, M. | 登録日 | 2012-02-20 | 公開日 | 2012-04-11 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.899 Å) | 主引用文献 | Structural analysis of Shu proteins reveals a DNA binding role essential for resisting damage J.Biol.Chem., 287, 2012
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1KEJ
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![BU of 1kej by Molmil](/molmil-images/mine/1kej) | Crystal Structure of Murine Terminal Deoxynucleotidyl Transferase complexed with ddATP | 分子名称: | 2',3'-DIDEOXYADENOSINE-5'-TRIPHOSPHATE, COBALT (II) ION, SODIUM ION, ... | 著者 | Delarue, M, Boule, J.B, Lescar, J, Expert-Bezancon, N, Jourdan, N, Sukumar, N, Rougeon, F, Papanicolaou, C. | 登録日 | 2001-11-16 | 公開日 | 2002-05-16 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystal structures of a template-independent DNA polymerase: murine terminal deoxynucleotidyltransferase. EMBO J., 21, 2002
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6WF5
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![BU of 6wf5 by Molmil](/molmil-images/mine/6wf5) | Crystal structure of human Naa50 in complex with a truncated cofactor derived inhibitor (compound 2) | 分子名称: | (2R)-2-hydroxy-3,3-dimethyl-N-{3-oxo-3-[(2-sulfanylethyl)amino]propyl}butanamide, ACE-MET-LEU-GLY-PRO-NH2, N-alpha-acetyltransferase 50 | 著者 | Greasley, S.E, Feng, J, Deng, Y.-L, Stewart, A.E. | 登録日 | 2020-04-03 | 公開日 | 2020-07-01 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | Characterization of SpecificN-alpha-Acetyltransferase 50 (Naa50) Inhibitors Identified Using a DNA Encoded Library. Acs Med.Chem.Lett., 11, 2020
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6NUE
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![BU of 6nue by Molmil](/molmil-images/mine/6nue) | Small conformation of apo CRISPR_Csm complex | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CRISPR system Cms protein Csm2, CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A), ... | 著者 | Zhang, K, Pintilie, G, Li, S, Zhu, Y, Chiu, W, Huang, Z. | 登録日 | 2019-01-31 | 公開日 | 2019-03-13 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Coupling of ssRNA cleavage with DNase activity in type III-A CRISPR-Csm revealed by cryo-EM and biochemistry. Cell Res., 29, 2019
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6WF3
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![BU of 6wf3 by Molmil](/molmil-images/mine/6wf3) | Crystal structure of human Naa50 in complex with a cofactor derived inhibitor (compound 1) | 分子名称: | ACE-MET-LEU-GLY-PRO-NH2, COENZYME A, N-alpha-acetyltransferase 50 | 著者 | Greasley, S.E, Feng, J, Deng, Y.-L, Stewart, A.E. | 登録日 | 2020-04-03 | 公開日 | 2020-07-01 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.291 Å) | 主引用文献 | Characterization of SpecificN-alpha-Acetyltransferase 50 (Naa50) Inhibitors Identified Using a DNA Encoded Library. Acs Med.Chem.Lett., 11, 2020
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5J0E
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![BU of 5j0e by Molmil](/molmil-images/mine/5j0e) | Crystal structures of Pribnow box consensus promoter sequence (P32) | 分子名称: | Complementary sequence, Pribnow box consensus promoter sequence, ZINC ION | 著者 | Mandal, P.K, Collie, G.W, Kauffmann, B, Huc, I. | 登録日 | 2016-03-28 | 公開日 | 2016-05-18 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | 主引用文献 | Structure elucidation of the Pribnow box consensus promoter sequence by racemic DNA crystallography. Nucleic Acids Res., 44, 2016
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436D
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3BVQ
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![BU of 3bvq by Molmil](/molmil-images/mine/3bvq) | Crystal Structure of Apo NotI Restriction Endonuclease | 分子名称: | FE (III) ION, NotI restriction endonuclease, SULFATE ION | 著者 | Lambert, A.R, Sussman, D, Shen, B, Stoddard, B.L. | 登録日 | 2008-01-07 | 公開日 | 2008-01-22 | 最終更新日 | 2017-10-25 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structures of the Rare-Cutting Restriction Endonuclease NotI Reveal a Unique Metal Binding Fold Involved in DNA Binding. Structure, 16, 2008
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4RSI
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4RSJ
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2W45
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![BU of 2w45 by Molmil](/molmil-images/mine/2w45) | Epstein-Barr virus alkaline nuclease | 分子名称: | ALKALINE EXONUCLEASE | 著者 | Buisson, M, Geoui, T, Flot, D, Tarbouriech, N, Burmeister, W.P. | 登録日 | 2008-11-21 | 公開日 | 2009-06-30 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | A Bridge Crosses the Active Site Canyon of the Epstein-Barr Virus Nuclease with DNase and Rnase Activity. J.Mol.Biol., 391, 2009
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3KIO
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![BU of 3kio by Molmil](/molmil-images/mine/3kio) | mouse RNase H2 complex | 分子名称: | Ribonuclease H2 subunit A, Ribonuclease H2 subunit B, Ribonuclease H2 subunit C | 著者 | Shaban, N, Harvey, S, Perrino, F.W, Hollis, T. | 登録日 | 2009-11-02 | 公開日 | 2009-11-17 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | The structure of the mammalian RNase H2 complex provides insight into RNA:DNA hybrid processing to prevent immune dysfunction. J.Biol.Chem., 285, 2010
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2XCS
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![BU of 2xcs by Molmil](/molmil-images/mine/2xcs) | The 2.1A crystal structure of S. aureus Gyrase complex with GSK299423 and DNA | 分子名称: | 5'-5UA*D(GP*CP*CP*GP*TP*AP*GP*GP*GP*CP*CP *CP*TP*AP*CP*GP*GP*CP*T)-3', 6-METHOXY-4-(2-{4-[([1,3]OXATHIOLO[5,4-C]PYRIDIN-6-YLMETHYL)AMINO]PIPERIDIN-1-YL}ETHYL)QUINOLINE-3-CARBONITRILE, DNA GYRASE SUBUNIT B, ... | 著者 | Bax, B.D, Chan, P.F, Eggleston, D.S, Fosberry, A, Gentry, D.R, Gorrec, F, Giordano, I, Hann, M.M, Hennessy, A, Hibbs, M, Huang, J, Jones, E, Jones, J, Brown, K.K, Lewis, C.J, May, E.W, Singh, O, Spitzfaden, C, Shen, C, Shillings, A, Theobald, A.F, Wohlkonig, A, Pearson, N.D, Gwynn, M.N. | 登録日 | 2010-04-25 | 公開日 | 2010-08-04 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Type Iia Topoisomerase Inhibition by a New Class of Antibacterial Agents. Nature, 466, 2010
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2QHB
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2XCR
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![BU of 2xcr by Molmil](/molmil-images/mine/2xcr) | The 3.5A crystal structure of the catalytic core (B'A' region) of Staphylococcus aureus DNA Gyrase complexed with GSK299423 and DNA | 分子名称: | 5'-D(*5UA*GP*CP*CP*GP*TP*AP*GP*GP*GP*CP*CP*CP*TP*AP*CP*GP *GP*CP*TP)-3', 5'-D(*AP*GP*CP*CP*GP*TP*AP*GP*GP*GP*CP*CP*CP*TP*AP*CP*GP *GP*CP*TP)-3', 6-METHOXY-4-(2-{4-[([1,3]OXATHIOLO[5,4-C]PYRIDIN-6-YLMETHYL)AMINO]PIPERIDIN-1-YL}ETHYL)QUINOLINE-3-CARBONITRILE, ... | 著者 | Bax, B.D, Chan, P.F, Eggleston, D.S, Fosberry, A, Gentry, D.R, Gorrec, F, Giordano, I, Hann, M.M, Hennessy, A, Hibbs, M, Huang, J, Jones, E, Jones, J, Brown, K.K, Lewis, C.J, May, E.W, Singh, O, Spitzfaden, C, Shen, C, Shillings, A, Theobald, A.F, Wohlkonig, A, Pearson, N.D, Gwynn, M.N. | 登録日 | 2010-04-25 | 公開日 | 2010-08-04 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Type Iia Topoisomerase Inhibition by a New Class of Antibacterial Agents. Nature, 466, 2010
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4WJA
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![BU of 4wja by Molmil](/molmil-images/mine/4wja) | Crystal Structure of PAXX | 分子名称: | Uncharacterized protein C9orf142 | 著者 | Xing, M, Yang, M, Huo, W, Feng, F, Wei, L, Ning, S, Yan, Z, Li, W, Wang, Q, Hou, M, Dong, C, Guo, R, Gao, G, Ji, J, Lan, L, Liang, H, Xu, D. | 登録日 | 2014-09-29 | 公開日 | 2015-03-11 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Interactome analysis identifies a new paralogue of XRCC4 in non-homologous end joining DNA repair pathway. Nat Commun, 6, 2015
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6OAB
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![BU of 6oab by Molmil](/molmil-images/mine/6oab) | Cdc48-Npl4 complex processing poly-ubiquitinated substrate in the presence of ADP-BeFx, state 2 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Cell division control protein 48, ... | 著者 | Twomey, E.C, Ji, Z, Wales, T.E, Bodnar, N.O, Engen, J.R, Rapoport, T.A. | 登録日 | 2019-03-15 | 公開日 | 2019-07-03 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Substrate processing by the Cdc48 ATPase complex is initiated by ubiquitin unfolding. Science, 365, 2019
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7Z4E
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![BU of 7z4e by Molmil](/molmil-images/mine/7z4e) | SpCas9 bound to 8-nucleotide complementary DNA substrate | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, Non-target strand of 8 nucleotide complementary DNA substrate, Target strand of 8 nucleotide complementary DNA substrate, ... | 著者 | Pacesa, M, Jinek, M. | 登録日 | 2022-03-03 | 公開日 | 2022-08-31 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (4.14 Å) | 主引用文献 | R-loop formation and conformational activation mechanisms of Cas9. Nature, 609, 2022
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