PDB: 30805 件ウェブページステータス検索Chemie searchBIRD

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8HMS	Crystal Structure of PKM2 mutant C474S 分子名称: 1,2-ETHANEDIOL, 1,6-di-O-phosphono-beta-D-fructofuranose, GLYCEROL, ... 著者 Upadhyay, S, Kumar, A, Patel, A.K. 登録日 2022-12-05 公開日 2023-01-11 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural and mechanistic insights into cancer patient-derived mutations in Pyruvate Kinase muscle isoform 2 To Be Published
5JZS	HsaD bound to 3,5-dichloro-4-hydroxybenzoic acid 分子名称: 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase BphD, 3,5-dichloro-4-hydroxybenzoic acid 著者 Ryan, A, Polycarpou, E, Lack, N, Evangelopoulos, D, Sieg, C, Halman, A, Bhakta, S, Sinclair, A, Eleftheriadou, O, McHugh, T.D, Keany, S, Lowe, E.D, Ballet, R, Abuhammad, A, Ciulli, A, Sim, E. 登録日 2016-05-17 公開日 2017-04-05 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 Investigation of the mycobacterial enzyme HsaD as a potential novel target for anti-tubercular agents using a fragment-based drug design approach. Br. J. Pharmacol., 174, 2017
8HMQ	Crystal Structure of PKM2 mutant P403A 分子名称: 1,2-ETHANEDIOL, 1,6-di-O-phosphono-beta-D-fructofuranose, GLYCEROL, ... 著者 Upadhyay, S, Kumar, A, Patel, A.K. 登録日 2022-12-05 公開日 2023-01-11 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural and mechanistic insights into cancer patient-derived mutations in Pyruvate Kinase muscle isoform 2 To Be Published
8HMR	Crystal Structure of PKM2 mutant L144P 分子名称: 1,2-ETHANEDIOL, 1,6-di-O-phosphono-beta-D-fructofuranose, MAGNESIUM ION, ... 著者 Upadhyay, S, Kumar, A, Patel, A.K. 登録日 2022-12-05 公開日 2023-01-11 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural and mechanistic insights into cancer patient-derived mutations in Pyruvate Kinase muscle isoform 2 To Be Published
5JX8	New improved structure of D4 in trigonal space group 分子名称: GLYCEROL, SULFATE ION, Uracil-DNA glycosylase 著者 Schormann, N, Chattopadhyay, D. 登録日 2016-05-12 公開日 2017-02-08 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Poxvirus uracil-DNA glycosylase-An unusual member of the family I uracil-DNA glycosylases. Protein Sci., 25, 2016
8IC6	exo-beta-D-arabinanase ExoMA2 from Microbacterium arabinogalactanolyticum in complex with Tris 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ... 著者 Fukushima, R, Kashima, T, Ishiwata, A, Fujita, K, Fushinobu, S. 登録日 2023-02-10 公開日 2023-08-16 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Identification and characterization of endo-alpha-, exo-alpha-, and exo-beta-D-arabinofuranosidases degrading lipoarabinomannan and arabinogalactan of mycobacteria. Nat Commun, 14, 2023
8I30	Crystal structure of the SARS-CoV-2 main protease in complex with 32j 分子名称: (2~{R})-1-[4,4-bis(fluoranyl)cyclohexyl]carbonyl-4,4-bis(fluoranyl)-~{N}-[(2~{R},3~{S})-3-oxidanyl-4-oxidanylidene-1-phenyl-4-(pyridin-2-ylmethylamino)butan-2-yl]pyrrolidine-2-carboxamide, 3C-like proteinase nsp5, CHLORIDE ION 著者 Zeng, R, Huang, C, Xie, L.W, Wang, K, Liu, Y.Z, Yang, S.Y, Lei, J. 登録日 2023-01-16 公開日 2023-08-16 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Discovery and structure-activity relationship studies of novel alpha-ketoamide derivatives targeting the SARS-CoV-2 main protease. Eur.J.Med.Chem., 259, 2023
5JYE	Structures of Streptococcus agalactiae GBS GAPDH in different enzymatic states 分子名称: Glyceraldehyde-3-phosphate dehydrogenase, MAGNESIUM ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Schormann, N, Chattopadhyay, D. 登録日 2016-05-13 公開日 2016-12-21 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.23 Å) 主引用文献 Crystal Structures of Group B Streptococcus Glyceraldehyde-3-Phosphate Dehydrogenase: Apo-Form, Binary and Ternary Complexes. PLoS ONE, 11, 2016
5K29	Trypanosoma brucei bromodomain BDF5 (Tb427tmp.01.5000) 分子名称: UNKNOWN ATOM OR ION, uncharacterized protein BDF5 著者 Lin, Y.H, Tempel, W, Walker, J.R, Loppnau, P, Amani, M, Hou, C.F.D, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Hui, R, Structural Genomics Consortium (SGC) 登録日 2016-05-18 公開日 2016-07-13 最終更新日 2016-11-02 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Trypanosoma brucei bromodomain BDF5 (Tb427tmp.01.5000) To Be Published
8IC8	Exo-alpha-D-arabinofuranosidase from Microbacterium arabinogalactanolyticum 分子名称: Exo-alpha-D-arabinofuranosidase, PHOSPHATE ION 著者 Kashima, T, Arakawa, T, Yamada, C, Ishiwata, A, Fujita, K, Fushinobu, S. 登録日 2023-02-11 公開日 2023-08-16 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.42 Å) 主引用文献 Identification and characterization of endo-alpha-, exo-alpha-, and exo-beta-D-arabinofuranosidases degrading lipoarabinomannan and arabinogalactan of mycobacteria. Nat Commun, 14, 2023
5JZM	Structure of wild type Amidase from Vibrio cholerae 0395 at low temparature at 1.8 Angstroms resolution. 分子名称: Intracellular protease/amidase 著者 Chowdhury, S.R, Sen, U. 登録日 2016-05-17 公開日 2016-06-15 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Structure of wild type Amidase from Vibrio cholerae 0395 at high temparature at 1.8 Angstroms resolution. To Be Published
5KH3	Crystal structure of fragment (3-(5-Chloro-1,3-benzothiazol-2-yl)propanoic acid) bound in the ubiquitin binding pocket of the HDAC6 zinc-finger domain 分子名称: 3-(5-chloranyl-1,3-benzothiazol-2-yl)propanoic acid, Histone deacetylase 6, UNKNOWN ATOM OR ION, ... 著者 Harding, R.J, Dong, A, Ravichandran, M, Ferreira de Freitas, R, Schapira, M, Bountra, C, Edwards, A.M, Santhakumar, V, Arrowsmith, C.M, Structural Genomics Consortium (SGC) 登録日 2016-06-14 公開日 2016-07-27 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Small Molecule Antagonists of the Interaction between the Histone Deacetylase 6 Zinc-Finger Domain and Ubiquitin. J. Med. Chem., 60, 2017
5JOD	Structure of proplasmepsin IV from Plasmodium falciparum 分子名称: GLYCEROL, Proplasmepsin IV 著者 Recacha, R, Akopjana, I, Tars, K, Jaudzems, K. 登録日 2016-05-02 公開日 2016-08-17 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.528 Å) 主引用文献 Crystal structure of Plasmodium falciparum proplasmepsin IV: the plasticity of proplasmepsins. Acta Crystallogr.,Sect.F, 72, 2016
5JOY	Bacteroides ovatus Xyloglucan PUL GH43A in complex with AraLOG 分子名称: (Z)-L-Arabinonhydroximo-1,4-lactone, 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... 著者 Thompson, A.J, Hemsworth, G.R, Stepper, J, Sobala, L.F, Coyle, T, Larsbrink, J, Spadiut, O, Stubbs, K.A, Brumer, H, Davies, G.J. 登録日 2016-05-03 公開日 2016-08-10 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural dissection of a complex Bacteroides ovatus gene locus conferring xyloglucan metabolism in the human gut. Open Biology, 6, 2016
8I0E	Sb3GT1 complex with UDP 分子名称: Glycosyltransferase, URIDINE-5'-DIPHOSPHATE 著者 Wang, H.T, Wang, Z.L, Ye, M. 登録日 2023-01-10 公開日 2023-09-20 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Insights into the missing apiosylation step in flavonoid apiosides biosynthesis of Leguminosae plants. Nat Commun, 14, 2023
5JRL	Crystal Structure of the Sphingopyxin I Lasso Peptide Isopeptidase SpI-IsoP (Native) 分子名称: Dipeptidyl aminopeptidases/acylaminoacyl-peptidases-like protein 著者 Fage, C.D, Hegemann, J.D, Bange, G, Marahiel, M.A. 登録日 2016-05-06 公開日 2016-09-14 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structure and Mechanism of the Sphingopyxin I Lasso Peptide Isopeptidase. Angew.Chem.Int.Ed.Engl., 55, 2016
8HZZ	GuApiGT (UGT79B74) 分子名称: SULFATE ION, apiosyltransferase 著者 Wang, H.T, Wang, Z.L, Li, F.D, Ye, M. 登録日 2023-01-10 公開日 2023-09-20 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Insights into the missing apiosylation step in flavonoid apiosides biosynthesis of Leguminosae plants. Nat Commun, 14, 2023
5JSM	BRAFV600E Kinase Domain In Complex with Chemically Linked Vemurafenib Inhibitor VEM-3-VEM 分子名称: BENZAMIDINE, CHLORIDE ION, DIMETHYL SULFOXIDE, ... 著者 Grasso, M.J, Marmorstein, R. 登録日 2016-05-08 公開日 2016-09-14 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.19 Å) 主引用文献 Chemically Linked Vemurafenib Inhibitors Promote an Inactive BRAF(V600E) Conformation. Acs Chem.Biol., 11, 2016
5JT4	L16A mutant of cytochrome c prime from Alcaligenes xylosoxidans: Ferrous state 分子名称: ASCORBIC ACID, Cytochrome c', HEME C, ... 著者 Kekilli, D, Strange, R.W, Hough, M.A. 登録日 2016-05-09 公開日 2017-03-08 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Engineering proximal vs. distal heme-NO coordination via dinitrosyl dynamics: implications for NO sensor design. Chem Sci, 8, 2017
5K78	Dbr1 in complex with 16-mer branched RNA 分子名称: FE (II) ION, RNA lariat debranching enzyme, putative, ... 著者 Clark, N.E, Taylor, A.B, Hart, P.J. 登録日 2016-05-25 公開日 2016-12-07 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.64 Å) 主引用文献 The RNA lariat debranching enzyme Dbr1: metal dependence and branched RNA co-crystal structures Proc.Natl.Acad.Sci.USA, 2016
8IA3	Crystal structure of human USF2 bHLHLZ domain in complex with DNA 分子名称: DNA (5'-D(*GP*CP*GP*CP*GP*TP*CP*AP*CP*GP*TP*GP*CP*CP*CP*GP*TP*C)-3'), DNA (5'-D(P*GP*AP*CP*GP*GP*GP*CP*AP*CP*GP*TP*GP*AP*CP*GP*CP*GP*C)-3'), Upstream stimulatory factor 2 著者 Huang, C, Fang, P, Wang, J. 登録日 2023-02-07 公開日 2023-09-20 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Tetramerization of upstream stimulating factor USF2 requires the elongated bent leucine zipper of the bHLH-LZ domain. J.Biol.Chem., 299, 2023
8I0D	Sb3GT1 375S/Q377H mutant complex with UDP-Glc 分子名称: Glycosyltransferase, URIDINE-5'-DIPHOSPHATE-GLUCOSE 著者 Wang, H.T, Wang, Z.L, Ye, M. 登録日 2023-01-10 公開日 2023-09-20 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.43 Å) 主引用文献 Insights into the missing apiosylation step in flavonoid apiosides biosynthesis of Leguminosae plants. Nat Commun, 14, 2023
5KAW	The structure of SAV2435 bound to TETRAPHENYLPHOSPHONIUM and RHODAMINE 6G 分子名称: GLYCEROL, RHODAMINE 6G, SA2223 protein, ... 著者 Moreno, A, Wade, H. 登録日 2016-06-02 公開日 2016-08-24 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Solution Binding and Structural Analyses Reveal Potential Multidrug Resistance Functions for SAV2435 and CTR107 and Other GyrI-like Proteins. Biochemistry, 55, 2016
8IBO	Crystal structure of Wild-Type Mycobacterium tuberculosis ClpC1 N-terminal domain in complex with Lassomycin 分子名称: ACETATE ION, Lassomycin, Negative regulator of genetic competence ClpC/mecB 著者 Jagdev, M.K, Vasudevan, D. 登録日 2023-02-10 公開日 2023-09-20 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Crystal structure of the N-terminal domain of MtClpC1 in complex with the anti-mycobacterial natural peptide Lassomycin. Int.J.Biol.Macromol., 253, 2023
8IBP	Crystal structure of Mycobacterium tuberculosis R21K ClpC1 N-terminal domain in complex with Lassomycin 分子名称: ACETATE ION, Lassomycin, Negative regulator of genetic competence ClpC/mecB 著者 Jagdev, M.K, Vasudevan, D. 登録日 2023-02-10 公開日 2023-09-20 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Crystal structure of the N-terminal domain of MtClpC1 in complex with the anti-mycobacterial natural peptide Lassomycin. Int.J.Biol.Macromol., 253, 2023

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