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4QYX
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Crystal structure of YDR533Cp
分子名称: Probable chaperone protein HSP31
著者Wilson, M.A, Amour, S.T, Collins, J.L, Ringe, D, Petsko, G.A.
登録日2014-07-26
公開日2014-08-06
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献The 1.8-A resolution crystal structure of YDR533Cp from Saccharomyces cerevisiae: A member of the DJ-1/ThiJ/PfpI superfamily.
Proc.Natl.Acad.Sci.USA, 101, 2004
2A24
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BU of 2a24 by Molmil
HADDOCK Structure of HIF-2a/ARNT PAS-B Heterodimer
分子名称: Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain protein 1
著者Card, P.B, Erbel, P.J, Gardner, K.H.
登録日2005-06-21
公開日2006-01-17
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structural basis of ARNT PAS-B dimerization: use of a common beta-sheet interface for hetero- and homodimerization.
J.Mol.Biol., 353, 2005
2KRG
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BU of 2krg by Molmil
Solution Structure of human sodium/ hydrogen exchange regulatory factor 1(150-358)
分子名称: Na(+)/H(+) exchange regulatory cofactor NHE-RF1
著者Bhattacharya, S, Dai, Z, Li, J, Baxter, S, Callaway, D.J.E, Cowburn, D, Bu, Z.
登録日2009-12-17
公開日2009-12-29
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献A conformational switch in the scaffolding protein NHERF1 controls autoinhibition and complex formation.
J.Biol.Chem., 285, 2010
5FNZ
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BU of 5fnz by Molmil
F206W mutant of FAD synthetase from Corynebacterium ammoniagenes
分子名称: PYROPHOSPHATE, RIBOFLAVIN BIOSYNTHESIS PROTEIN RIBF, SULFATE ION
著者Martinez-Julvez, M, Herguedas, B, Milagros, M.
登録日2015-11-17
公開日2016-11-30
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献The trimer interface in the quaternary structure of the bifunctional prokaryotic FAD synthetase from Corynebacterium ammoniagenes.
Sci Rep, 7, 2017
6LOG
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BU of 6log by Molmil
Crystal structure of human CCL5-12AAA14 mutant
分子名称: C-C motif chemokine 5
著者Chen, Y.C, Li, J.Y, Huang, C.H, Sue, S.C.
登録日2020-01-05
公開日2020-03-18
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献N-terminal Backbone Pairing Shifts in CCL5- 12 AAA 14 Dimer Interface: Structural Significance of the FAY Sequence.
Int J Mol Sci, 21, 2020
1QDV
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BU of 1qdv by Molmil
N-TERMINAL DOMAIN, VOLTAGE-GATED POTASSIUM CHANNEL KV1.2 RESIDUES 33-131
分子名称: KV1.2 VOLTAGE-GATED POTASSIUM CHANNEL
著者Minor Jr, D.L, Lin, Y.-F, Mobley, B.C, Yu, M, Jan, Y.N, Jan, L.Y, Berger, J.M.
登録日1999-07-10
公開日2000-09-20
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The polar T1 interface is linked to conformational changes that open the voltage-gated potassium channel.
Cell(Cambridge,Mass.), 102, 2000
1GQE
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BU of 1gqe by Molmil
Polypeptide Chain Release Factor 2 (RF2) from Escherichia coli
分子名称: RELEASE FACTOR 2
著者Vestergaard, B, Kjeldgaard, M.
登録日2001-11-22
公開日2002-04-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Bacterial Polypeptide Release Factor Rf2 is Structurally Distinct from Eukaryotic Erf1.
Mol.Cell, 8, 2001
1QDW
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N-TERMINAL DOMAIN, VOLTAGE-GATED POTASSIUM CHANNEL KV1.2 RESIDUES 33-119
分子名称: KV1.2 VOLTAGE-GATED POTASSIUM CHANNEL
著者Minor Jr, D.L, Lin, Y.-F, Mobley, B.C, Avelar, A, Jan, Y.N, Jan, L.Y, Berger, J.M.
登録日1999-07-10
公開日2000-09-20
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The polar T1 interface is linked to conformational changes that open the voltage-gated potassium channel.
Cell(Cambridge,Mass.), 102, 2000
8CP5
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BU of 8cp5 by Molmil
Structure of Aspartate-N-hydroxylase (FzmM)from Streptomyces sp. V2: complex with NADPH and Sulphate
分子名称: DI(HYDROXYETHYL)ETHER, FAD-binding protein, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Rotilio, L, Mattevi, A.
登録日2023-03-01
公開日2023-07-12
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.54 Å)
主引用文献A biosynthetic aspartate N-hydroxylase performs successive oxidations by holding intermediates at a site away from the catalytic center.
J.Biol.Chem., 299, 2023
8CP2
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BU of 8cp2 by Molmil
Structure of Aspartate-N-hydroxylase (FzmM)from Streptomyces sp. V2: complex with NADPH and L-aspartate
分子名称: 3-NITROPROPANOIC ACID, ASPARTIC ACID, DI(HYDROXYETHYL)ETHER, ...
著者Rotilio, L, Mattevi, A.
登録日2023-03-01
公開日2023-07-12
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A biosynthetic aspartate N-hydroxylase performs successive oxidations by holding intermediates at a site away from the catalytic center.
J.Biol.Chem., 299, 2023
5XD9
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BU of 5xd9 by Molmil
Crystal structure analysis of 3,6-anhydro-L-galactonate cycloisomerase
分子名称: 3,6-anhydro-alpha-L-galactonate cycloisomerase, MAGNESIUM ION
著者Lee, S, Choi, I.-G, Kim, H.-Y.
登録日2017-03-27
公開日2017-09-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure analysis of 3,6-anhydro-l-galactonate cycloisomerase suggests emergence of novel substrate specificity in the enolase superfamily
Biochem. Biophys. Res. Commun., 491, 2017
1HF0
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BU of 1hf0 by Molmil
Crystal structure of the DNA-binding domain of Oct-1 bound to DNA as a dimer
分子名称: DNA 5'-D(*CP*AP*CP*AP*TP*TP*TP*GP*AP*AP*AP*GP*GP* CP*AP*AP*AP*TP*GP*GP*AP*G)-3', DNA 5'-D(*CP*TP*CP*CP*AP*TP*TP*TP*GP*CP*CP*TP*TP* TP*CP*AP*AP*AP*TP*GP*TP*G)-3', OCTAMER-BINDING TRANSCRIPTION FACTOR 1
著者Remenyi, A, Tomilin, A, Pohl, E, Scholer, H.R, Wilmanns, M.
登録日2000-11-27
公開日2001-11-10
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Differential Dimer Activities of the Transcription Factor Oct-1 by DNA-Induced Interface Swapping
Mol.Cell, 8, 2001
5BXX
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BU of 5bxx by Molmil
Crystal structure of the ectoine synthase from the cold-adapted marine bacterium Sphingopyxis alaskensis
分子名称: L-ectoine synthase
著者Widderich, N, Kobus, S, Hoeppner, A, Bremer, E, Smits, S.H.J.
登録日2015-06-09
公開日2016-04-27
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Biochemistry and Crystal Structure of Ectoine Synthase: A Metal-Containing Member of the Cupin Superfamily.
Plos One, 11, 2016
6O47
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human cGAS core domain (K427E/K428E) bound with RU-521
分子名称: (3~{S})-3-[1-[4,5-bis(chloranyl)-1~{H}-benzimidazol-2-yl]-3-methyl-5-oxidanyl-pyrazol-4-yl]-3~{H}-2-benzofuran-1-one, 2-(4,5-dichloro-1H-benzimidazol-2-yl)-5-methyl-4-[(1R)-3-oxo-1,3-dihydro-2-benzofuran-1-yl]-1,2-dihydro-3H-pyrazol-3-one, CITRIC ACID, ...
著者Xie, W, Lama, L, Adura, C, Glickman, J.F, Tuschl, T, Patel, D.J.
登録日2019-02-28
公開日2019-05-29
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.196 Å)
主引用文献Human cGAS catalytic domain has an additional DNA-binding interface that enhances enzymatic activity and liquid-phase condensation.
Proc.Natl.Acad.Sci.USA, 116, 2019
6EFE
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BU of 6efe by Molmil
NMR Solution Structure of vil14a
分子名称: Kappa-conotoxin vil14a
著者Dovell, S, Mari, F, Moller, C, Melaun, C.
登録日2018-08-16
公開日2018-09-05
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Definition of the R-superfamily of conotoxins: Structural convergence of helix-loop-helix peptidic scaffolds.
Peptides, 107, 2018
5UNQ
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Crystal Structure of Pt0534 Inactivated by 2-Oxo-3-pentynoate
分子名称: Putative tautomerase
著者LeVieux, J, Baas, B.J, Zhang, Y.J, Whitman, C.P.
登録日2017-01-31
公開日2017-11-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.976 Å)
主引用文献A global view of structure-function relationships in the tautomerase superfamily.
J. Biol. Chem., 293, 2018
2PJY
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BU of 2pjy by Molmil
Structural basis for cooperative assembly of the TGF-beta signaling complex
分子名称: TGF-beta receptor type-1, TGF-beta receptor type-2, Transforming growth factor beta-3
著者Groppe, J, Zubieta, C.
登録日2007-04-16
公開日2008-02-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Cooperative assembly of TGF-beta superfamily signaling complexes is mediated by two disparate mechanisms and distinct modes of receptor binding.
Mol.Cell, 29, 2008
6FI9
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BU of 6fi9 by Molmil
Crystal Structure of a zinc-responsive MarR family member, Lactococcus lactis ZitR
分子名称: Transcriptional regulator ZitR, ZINC ION
著者Varela, P.F, Legrand, P.
登録日2018-01-17
公開日2019-02-20
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Biophysical and structural characterization of a zinc-responsive repressor of the MarR superfamily.
PLoS ONE, 14, 2019
7ALN
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BU of 7aln by Molmil
Cryo-EM structure of the divergent actomyosin complex from Plasmodium falciparum Myosin A in the Rigor state
分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin-1, Jasplakinolide, ...
著者Robert-Paganin, J, Xu, X.-P, Swift, M.F, Auguin, D, Robblee, J.P, Lu, H, Fagnant, P.M, Krementsova, E.B, Trybus, K.M, Houdusse, A, Volkmann, N, Hanein, D.
登録日2020-10-06
公開日2021-04-28
実験手法ELECTRON MICROSCOPY (3.77 Å)
主引用文献The actomyosin interface contains an evolutionary conserved core and an ancillary interface involved in specificity.
Nat Commun, 12, 2021
2KQM
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Solution structure of the KI O18/O8 Y87H immunoglobulin light chain variable domain
分子名称: Ig kappa chain V-I region AU
著者Volkman, B.F, Peterson, F.C, Ramirez-Alvarado, M, Baden, E.M.
登録日2009-11-11
公開日2010-03-16
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献A single mutation promotes amyloidogenicity through a highly promiscuous dimer interface.
Structure, 18, 2010
2LKY
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BU of 2lky by Molmil
Solution structure of MSMEG_1053, the second DUF3349 annotated protein in the genome of Mycobacterium smegmatis, Seattle Structural Genomics Center for Infectious Disease target MysmA.17112.b
分子名称: Uncharacterized protein
著者Buchko, G.W, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2011-10-22
公開日2011-11-16
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural diversity in the Mycobacteria DUF3349 superfamily.
Protein Sci., 29, 2020
2KQN
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Solution structure of the AL-09 H87Y immunoglobulin light chain variable domain
分子名称: Ig kappa chain V-I region AU
著者Volkman, B.F, Peterson, F.C, Ramirez-Alvarado, M, Baden, E.M.
登録日2009-11-11
公開日2010-03-16
最終更新日2022-03-16
実験手法SOLUTION NMR
主引用文献A single mutation promotes amyloidogenicity through a highly promiscuous dimer interface.
Structure, 18, 2010
2M0N
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Solution structure of a DUF3349 annotated protein from Mycobacterium abscessus, MAB_3403c. Seattle Structural Genomics Center for Infectious Disease target MyabA.17112.a.A2
分子名称: Putative uncharacterized protein
著者Buchko, G.W, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2012-10-30
公開日2012-11-21
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural diversity in the Mycobacteria DUF3349 superfamily.
Protein Sci., 29, 2020
6QYQ
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Crystal structure of human thymidylate synthase (hTS) variant R175C
分子名称: CHLORIDE ION, N-[4-({[(6S)-2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid, SULFATE ION, ...
著者Pozzi, C, Mangani, M.
登録日2019-03-09
公開日2019-04-17
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural and Functional Characterization of the Human Thymidylate Synthase (hTS) Interface Variant R175C, New Perspectives for the Development of hTS Inhibitors.
Molecules, 24, 2019
6VIE
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Structure of caspase-1 in complex with gasdermin D
分子名称: Caspase-1 subunit p10, Caspase-1 subunit p20, Gasdermin-D
著者Liu, Z, Xiao, T.S.
登録日2020-01-13
公開日2020-07-01
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Caspase-1 Engages Full-Length Gasdermin D through Two Distinct Interfaces That Mediate Caspase Recruitment and Substrate Cleavage.
Immunity, 53, 2020

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