PDB: 226262 件ウェブページステータス検索Chemie searchBIRD

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8HCR	Cryo-EM structure of the Mycobacterium tuberculosis cytochrome bcc:aa3 supercomplex and a novel inhibitor targeting subunit cytochrome cI 分子名称: CYTOCHROME AA3 SUBUNIT CtaC, CYTOCHROME AA3 SUBUNIT CtaJ, Cytochrome bc1 complex Rieske iron-sulfur subunit, ... 著者 Mathiyazakan, V, Gruber, G. 登録日 2022-11-02 公開日 2023-05-03 最終更新日 2023-09-13 実験手法 ELECTRON MICROSCOPY 主引用文献 Cryo-Electron Microscopy Structure of the Mycobacterium tuberculosi s Cytochrome bcc : aa 3 Supercomplex and a Novel Inhibitor Targeting Subunit Cytochrome c I. Antimicrob.Agents Chemother., 67, 2023
4URA	Crystal structure of human JMJD2A in complex with compound 14a 分子名称: 1,2-ETHANEDIOL, 2-(2H-1,2,3-triazol-4-yl)pyridine-4-carboxylic acid, LYSINE-SPECIFIC DEMETHYLASE 4A, ... 著者 Krojer, T, England, K.S, Vollmar, M, Crawley, L, Williams, E, Riesebos, E, Szykowska, A, Burgess-Brown, N, Oppermann, U, Brennan, P.E, Bountra, C, Arrowsmith, C.H, Edwards, A, von Delft, F. 登録日 2014-06-27 公開日 2015-06-17 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.23 Å) 主引用文献 Optimisation of a triazolopyridine based histone demethylase inhibitor yields a potent and selective KDM2A (FBXL11) inhibitor. Medchemcomm, 5, 2014
2RMK	Rac1/PRK1 Complex 分子名称: MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, Ras-related C3 botulinum toxin substrate 1, ... 著者 Modha, R, Campbell, L.J, Nietlispach, D, Buhecha, H.R, Owen, D, Mott, H.R. 登録日 2007-10-25 公開日 2007-11-13 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 The Rac1 Polybasic Region Is Required for Interaction with Its Effector PRK1 J.Biol.Chem., 283, 2008
8H3J	Crystal Structure of Pathogenesis-related Protein HcPR10 from Halostachys caspica in complex with trans-Zeatin-riboside 分子名称: N-[(2E)-4-hydroxy-3-methylbut-2-en-1-yl]adenosine, PR10 著者 Wang, Z, Ren, Y. 登録日 2022-10-08 公開日 2023-05-17 最終更新日 2024-07-17 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Halostachys caspica pathogenesis-related protein 10 acts as a cytokinin reservoir to regulate plant growth and development. Front Plant Sci, 14, 2023
2ROK	Solution structure of the cap-binding domain of PARN complexed with the cap analog 分子名称: 7N-METHYL-8-HYDROGUANOSINE-5'-MONOPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, poly(A)-specific ribonuclease 著者 Nagata, T, Suzuki, S, Endo, R, Shirouzu, M, Terada, T, Inoue, M, Kigawa, T, Guntert, P, Hayashizaki, Y, Muto, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2008-03-28 公開日 2009-02-10 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 The RRM domain of poly(A)-specific ribonuclease has a noncanonical binding site for mRNA cap analog recognition. Nucleic Acids Res., 36, 2008
8HN7	Crystal structure of monoclonal antibody complexed with SARS-CoV-2 RBD 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of monoclonal antibody 3C11, Light chain of monoclonal antibody 3C11, ... 著者 Qi, J, Chen, Y. 登録日 2022-12-07 公開日 2023-05-17 最終更新日 2023-06-07 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Characterization of RBD-specific cross-neutralizing antibodies responses against SARS-CoV-2 variants from COVID-19 convalescents. Front Immunol, 14, 2023
4UTT	Structural characterisation of NanE, ManNac6P C2 epimerase, from Clostridium perfingens 分子名称: ACETATE ION, CHLORIDE ION, PUTATIVE N-ACETYLMANNOSAMINE-6-PHOSPHATE 2-EPIMERASE 著者 Pelissier, M.C, Sebban-Kreuzer, C, Guerlesquin, F, Brannigan, J.A, Davies, G.J, Bourne, Y, Vincent, F. 登録日 2014-07-23 公開日 2014-10-22 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.71 Å) 主引用文献 Structural and Functional Characterization of the Clostridium Perfringens N-Acetylmannosamine-6-Phosphate 2-Epimerase Essential for the Sialic Acid Salvage Pathway. J.Biol.Chem., 289, 2014
8H6C	Crystal structure of human GCN5 histone acetyltransferase domain bound with malonyl-CoA 分子名称: Histone acetyltransferase KAT2A, MALONYL-COENZYME A 著者 Li, N, Tao, Y.J, Guo, Y.R. 登録日 2022-10-16 公開日 2023-05-03 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Molecular Basis of KAT2A Selecting Acyl-CoA Cofactors for Histone Modifications. Res, 6, 2023
2STT	SOLUTION NMR STRUCTURE OF THE HUMAN ETS1/DNA COMPLEX, 25 STRUCTURES 分子名称: DNA (5'-D(*TP*CP*GP*AP*AP*CP*TP*TP*CP*CP*GP*GP*CP*TP*CP*GP*A)-3'), DNA (5'-D(*TP*CP*GP*AP*GP*CP*CP*GP*GP*AP*AP*GP*TP*TP*CP*GP*A)-3'), ETS1 著者 Clore, G.M, Werner, M.H, Gronenborn, A.M. 登録日 1996-08-05 公開日 1997-03-12 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Correction of the NMR structure of the ETS1/DNA complex. J.Biomol.NMR, 10, 1997
4UXB	Human ARTD1 (PARP1) - Catalytic domain in complex with inhibitor PJ34 分子名称: N~2~,N~2~-DIMETHYL-N~1~-(6-OXO-5,6-DIHYDROPHENANTHRIDIN-2-YL)GLYCINAMIDE, POLY ADP-RIBOSE POLYMERASE 1, SULFATE ION 著者 Tresaugues, L, Thorsell, A.G, Karlberg, T, Schuler, H. 登録日 2014-08-21 公開日 2015-09-02 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.22 Å) 主引用文献 Structural Basis for Potency and Promiscuity in Poly(ADP-ribose) Polymerase (PARP) and Tankyrase Inhibitors. J. Med. Chem., 60, 2017
8H9U	Human ATP synthase state 3a (combined) 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase F(0) complex subunit B1, ... 著者 Lai, Y, Zhang, Y, Liu, F, Gao, Y, Gong, H, Rao, Z. 登録日 2022-10-25 公開日 2023-05-31 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (2.61 Å) 主引用文献 Structure of the human ATP synthase. Mol.Cell, 83, 2023
2TCI	X-RAY CRYSTALLOGRAPHIC STUDIES ON HEXAMERIC INSULINS IN THE PRESENCE OF HELIX-STABILIZING AGENTS, THIOCYANATE, METHYLPARABEN AND PHENOL 分子名称: THIOCYANATE INSULIN, THIOCYANATE ION, ZINC ION 著者 Whittingham, J.L, Dodson, E.J, Moody, P.C.E, Dodson, G.G. 登録日 1995-09-13 公開日 1996-01-29 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 X-ray crystallographic studies on hexameric insulins in the presence of helix-stabilizing agents, thiocyanate, methylparaben, and phenol. Biochemistry, 34, 1995
4UZC	KSHV LANA (ORF73) C-terminal domain, spiral: hexagonal crystal form 分子名称: ORF 73 著者 Hellert, J, Krausze, J, Luhrs, T. 登録日 2014-09-05 公開日 2015-05-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.7 Å) 主引用文献 The 3D Structure of Kaposi Sarcoma Herpesvirus Lana C-Terminal Domain Bound to DNA. Proc.Natl.Acad.Sci.USA, 112, 2015
8H3M	Conformation 1 of SARS-CoV-2 Omicron BA.1 Variant Spike protein complexed with MO1 Fab 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, MO1 heavy chain, Spike glycoprotein 著者 Ishimaru, H, Nishimura, M, Sutandhio, S, Shigematsu, H, Kato, K, Hasegawa, N, Mori, Y. 登録日 2022-10-09 公開日 2023-05-10 最終更新日 2023-08-02 実験手法 ELECTRON MICROSCOPY (2.48 Å) 主引用文献 Identification and Analysis of Monoclonal Antibodies with Neutralizing Activity against Diverse SARS-CoV-2 Variants. J.Virol., 97, 2023
4V45	E. COLI (lacZ) BETA-GALACTOSIDASE-TRAPPED 2-F-GALACTOSYL-ENZYME INTERMEDIATE 分子名称: 2-deoxy-2-fluoro-beta-D-galactopyranose, Beta-Galactosidase, MAGNESIUM ION, ... 著者 Juers, D.H, McCarter, J.D, Withers, S.G, Matthews, B.W. 登録日 2001-09-13 公開日 2014-07-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 A Structural View of the Action of Escherichia Coli (Lacz) Beta-Galactosidase Biochemistry, 40, 2001
4V4M	1.45 Angstrom Structure of STNV coat protein 分子名称: CALCIUM ION, Coat protein 著者 Lane, S.W, Dennis, C.A, Lane, C.L, Trinh, C.H, Rizkallah, P.J, Stockley, P.G, Phillips, S.E.V. 登録日 2011-04-28 公開日 2014-07-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Construction and crystal structure of recombinant STNV capsids. J.Mol.Biol., 413, 2011
8H56	Crystal structure of Rep' of porcine circovirus type 2 分子名称: Isoform Rep' of Replication-associated protein 著者 Guan, S.Y, Song, Y.F. 登録日 2022-10-12 公開日 2023-05-24 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.33 Å) 主引用文献 Crystal structure of the dimerized of porcine circovirus type II replication-related protein Rep'. Proteins, 91, 2023
2RP3	Solution Structure of Cyanovirin-N Domain B Mutant 分子名称: Cyanovirin-N 著者 Matei, E, Furey, W, Gronenborn, A.M. 登録日 2008-04-30 公開日 2008-08-19 最終更新日 2021-11-10 実験手法 SOLUTION NMR 主引用文献 Solution and crystal structures of a sugar binding site mutant of cyanovirin-N: no evidence of domain swapping Structure, 16, 2008
2RPN	A crucial role for high intrinsic specificity in the function of yeast SH3 domains 分子名称: Actin-binding protein, Actin-regulating kinase 1 著者 Stollar, E.J, Garcia, B, Chong, A, Forman-Kay, J, Davidson, A. 登録日 2008-06-12 公開日 2009-06-16 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Structural, functional, and bioinformatic studies demonstrate the crucial role of an extended peptide binding site for the SH3 domain of yeast Abp1p J.Biol.Chem., 284, 2009
8H9V	Human ATP synthase state 3b (combined) 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase F(0) complex subunit B1, ... 著者 Lai, Y, Zhang, Y, Liu, F, Gao, Y, Gong, H, Rao, Z. 登録日 2022-10-25 公開日 2023-05-31 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (3.02 Å) 主引用文献 Structure of the human ATP synthase. Mol.Cell, 83, 2023
4V8T	Cryo-EM Structure of the 60S Ribosomal Subunit in Complex with Arx1 and Rei1 分子名称: 25S RIBOSOMAL RNA, 5.8S RIBOSOMAL RNA, 5S RIBOSOMAL RNA, ... 著者 Greber, B.J, Boehringer, D, Montellese, C, Ban, N. 登録日 2012-08-07 公開日 2014-07-09 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (8.1 Å) 主引用文献 Cryo-Em Structures of Arx1 and Maturation Factors Rei1 and Jjj1 Bound to the 60S Ribosomal Subunit Nat.Struct.Mol.Biol., 19, 2012
8HFA	The structure of chitin deacetylase VdPDA1 from Verticillium dahliae 分子名称: NodB homology domain-containing protein, ZINC ION 著者 Liu, L, Zhou, Y, Yang, Q. 登録日 2022-11-10 公開日 2023-05-31 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.64 Å) 主引用文献 Inhibition of chitin deacetylases to attenuate plant fungal diseases. Nat Commun, 14, 2023
2RI3	Crystal structure of the 3-MBT repeats from human L3MBTL1 with N358Q point mutation 分子名称: DI(HYDROXYETHYL)ETHER, Lethal(3)malignant brain tumor-like protein 著者 Li, H, Patel, D.J. 登録日 2007-10-10 公開日 2007-12-11 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural Basis for Lower Lysine Methylation State-Specific Readout by MBT Repeats of L3MBTL1 and an Engineered PHD Finger. Mol.Cell, 28, 2007
4V96	The structure of a 1.8 MDa viral genome injection device suggests alternative infection mechanisms 分子名称: BPP, ORF46, ORF48 著者 Veesler, D, Spinelli, S, Mahony, J, Lichiere, J, Blangy, S, Bricogne, G, Legrand, P, Ortiz-Lombardia, M, Campanacci, V, van Sinderen, D, Cambillau, C. 登録日 2012-02-01 公開日 2014-07-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.8 Å) 主引用文献 Structure of the phage TP901-1 1.8 MDa baseplate suggests an alternative host adhesion mechanism. Proc.Natl.Acad.Sci.USA, 109, 2012
8HB9	Crystal Structure of Human IDH1 R132H Mutant in Complex with NADPH and Compound IHMT-IDH1-053 分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, Isocitrate dehydrogenase [NADP] cytoplasmic, ... 著者 Guo, G, Wang, B, Liu, J, Liu, Q. 登録日 2022-10-27 公開日 2023-05-24 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure-based discovery of IHMT-IDH1-053 as a potent irreversible IDH1 mutant selective inhibitor. Eur.J.Med.Chem., 256, 2023

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