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1RGQ
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M9A HCV Protease complex with pentapeptide keto-amide inhibitor
分子名称: N-(PYRAZIN-2-YLCARBONYL)LEUCYLISOLEUCYL-N~1~-{1-[2-({1-CARBOXY-2-[4-(PHOSPHONOOXY)PHENYL]ETHYL}AMINO)-1,1-DIHYDROXY-2-OXOETHYL]BUT-3-ENYL}-3-CYCLOHEXYLALANINAMIDE, NS3 Protease, NS4A peptide, ...
著者Liu, Y, Stoll, V.S, Richardson, P.L, Saldivar, A, Klaus, J.L, Molla, A, Kohlbrenner, W, Kati, W.M.
登録日2003-11-12
公開日2004-10-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Hepatitis C NS3 protease inhibition by peptidyl-alpha-ketoamide inhibitors: kinetic mechanism and structure.
Arch.Biochem.Biophys., 421, 2004
4HSA
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BU of 4hsa by Molmil
Structure of interleukin 17a in complex with il17ra receptor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-17 receptor A, ...
著者Liu, S.
登録日2012-10-29
公開日2013-05-22
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Crystal structures of interleukin 17A and its complex with IL-17 receptor A.
Nat Commun, 4, 2013
2M7Y
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BU of 2m7y by Molmil
The Mengovirus Leader protein
分子名称: Leader peptide, ZINC ION
著者Cornilescu, C.C, Porter, F.W, Zhao, K.Q, Davis, V, Palmenberg, A.C, Markley, J.L.
登録日2013-05-02
公開日2013-10-23
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Full Length Mengovirus Leader
To be Published
1SVB
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BU of 1svb by Molmil
ENVELOPE GLYCOPROTEIN FROM TICK-BORNE ENCEPHALITIS VIRUS
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, TICK-BORNE ENCEPHALITIS VIRUS GLYCOPROTEIN
著者Rey, F.A, Harrison, S.C.
登録日1995-11-27
公開日1996-06-10
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The envelope glycoprotein from tick-borne encephalitis virus at 2 A resolution.
Nature, 375, 1995
3FGH
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BU of 3fgh by Molmil
Human mitochondrial transcription factor A box B
分子名称: CADMIUM ION, CHLORIDE ION, SODIUM ION, ...
著者Gangelhoff, T.A, Mungalachetty, P, Nix, J, Churchill, M.E.A.
登録日2008-12-06
公開日2009-04-07
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Structural analysis and DNA binding of the HMG domains of the human mitochondrial transcription factor A
Nucleic Acids Res., 37, 2009
2MTS
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BU of 2mts by Molmil
Three-Dimensional Structure and Interaction Studies of Hepatitis C Virus p7 in 1,2-Dihexanoyl-sn-glycero-3-phosphocholine by Solution Nuclear Magnetic Resonance
分子名称: HEPATITIS C VIRUS P7 PROTEIN
著者Cook, G.A, Dawson, L.A, Tian, Y, Opella, S.J.
登録日2014-08-29
公開日2014-10-15
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Three-dimensional structure and interaction studies of hepatitis C virus p7 in 1,2-dihexanoyl-sn-glycero-3-phosphocholine by solution nuclear magnetic resonance.
Biochemistry, 52, 2013
2N1P
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BU of 2n1p by Molmil
Structure of the C-terminal membrane domain of HCV NS5B protein
分子名称: Non-structural protein 5B, NS5B
著者Montserret, R, Penin, F.
登録日2015-04-15
公開日2016-04-20
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structure of the C-terminal membrane domain of HCV NS5B protein.
To be Published
2O8M
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BU of 2o8m by Molmil
Crystal structure of the S139A mutant of Hepatitis C Virus NS3/4A protease
分子名称: Protease, SODIUM ION, ZINC ION
著者Fischmann, T.O, Prongay, A.J, Madison, V.M, Yao, N.
登録日2006-12-12
公開日2007-10-09
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Discovery of the HCV NS3/4A protease inhibitor (1R,5S)-N-[3-amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]-3- [2(S)-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]- 6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2(S)-carboxamide (Sch 503034) II. Key steps in structure-based optimization
J.Med.Chem., 50, 2007
7EL2
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BU of 7el2 by Molmil
Crystal structure of apo-HpaR from Acinetobacter baumannii
分子名称: Homoprotocatechuate degradation operon regulator HpaR
著者Permsirivisarn, P, Pakotiprapha, D.
登録日2021-04-07
公開日2022-01-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Mechanism of transcription regulation by Acinetobacter baumannii HpaR in the catabolism of p-hydroxyphenylacetate.
Febs J., 289, 2022
7EL3
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BU of 7el3 by Molmil
Crystal structure of HpaR-DNA complex from Acinetobacter baumannii
分子名称: Chains: C, Chains: D, GLYCEROL, ...
著者Permsirivisarn, P, Pakotiprapha, D.
登録日2021-04-07
公開日2022-01-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Mechanism of transcription regulation by Acinetobacter baumannii HpaR in the catabolism of p-hydroxyphenylacetate.
Febs J., 289, 2022
2KEQ
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BU of 2keq by Molmil
Solution structure of DnaE intein from Nostoc punctiforme
分子名称: DNA polymerase III alpha subunit, Nucleic acid binding OB-fold tRNA/helicase-type
著者Oeemig, J.S, Aranko, A.S, Djupsj, J.B, Iwai, H.
登録日2009-02-02
公開日2009-05-19
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of DnaE intein from Nostoc punctiforme: structural basis for the design of a new split intein suitable for site-specific chemical modification.
Febs Lett., 583, 2009
4GIZ
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BU of 4giz by Molmil
Crystal structure of full-length human papillomavirus oncoprotein E6 in complex with LXXLL peptide of ubiquitin ligase E6AP at 2.55 A resolution
分子名称: Maltose-binding periplasmic protein, UBIQUITIN LIGASE EA6P: chimeric protein, Protein E6, ...
著者McEwen, A.G, Zanier, K, Charbonnier, S, Poussin, P, Cura, V, Vande Pol, S, Trave, G, Cavarelli, J.
登録日2012-08-09
公開日2013-01-23
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structural basis for hijacking of cellular LxxLL motifs by papillomavirus E6 oncoproteins.
Science, 339, 2013
2HYE
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BU of 2hye by Molmil
Crystal Structure of the DDB1-Cul4A-Rbx1-SV5V Complex
分子名称: Cullin-4A, DNA damage-binding protein 1, Nonstructural protein V, ...
著者Angers, S, Li, T, Yi, X, MacCoss, M.J, Moon, R.T, Zheng, N.
登録日2006-08-05
公開日2006-10-03
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery.
Nature, 443, 2006
2P5P
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BU of 2p5p by Molmil
Crystal Structure Analysis of the West Nile virus envelope (E) protein domain III
分子名称: Genome polyprotein
著者Gao, F, Yuan, F, Gao, G.F.
登録日2007-03-16
公開日2008-03-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal Structure Analysis of the West Nile virus envelope (E) protein domain III
To be Published
2K9H
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BU of 2k9h by Molmil
The hantavirus glycoprotein G1 tail contains a dual CCHC-type classical zinc fingers
分子名称: Glycoprotein, ZINC ION
著者Estrada, D.F, Boudreaux, D.M, Zhong, D, St Jeor, S.C, De Guzman, R.N.
登録日2008-10-13
公開日2009-01-27
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The Hantavirus Glycoprotein G1 Tail Contains Dual CCHC-type Classical Zinc Fingers.
J.Biol.Chem., 284, 2009
4I77
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BU of 4i77 by Molmil
Lebrikizumab Fab bound to IL-13
分子名称: Interleukin-13, Lebrikizumab heavy chain, Lebrikizumab light chain
著者Eigenbrot, C, Ultsch, M.
登録日2012-11-30
公開日2013-02-06
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Basis of Signaling Blockade by Anti-IL-13 Antibody Lebrikizumab.
J.Mol.Biol., 425, 2013
3GAN
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BU of 3gan by Molmil
Crystal structure of gene product from Arabidopsis thaliana At3g22680 with bound suramin
分子名称: 8,8'-[CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO]]BIS-1,3,5-NAPHTHALENETRISULFON IC ACID, CHLORIDE ION, Uncharacterized protein At3g22680
著者Burgie, E.S, Bingman, C.A, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG)
登録日2009-02-17
公開日2009-03-03
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of gene product from Arabidopsis thaliana At3g22680 with bound suramin
To be Published
1HV2
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BU of 1hv2 by Molmil
SOLUTION STRUCTURE OF YEAST ELONGIN C IN COMPLEX WITH A VON HIPPEL-LINDAU PEPTIDE
分子名称: ELONGIN C, VON HIPPEL-LINDAU DISEASE TUMOR SUPPRESSOR
著者Botuyan, M.V, Mer, G, Yi, G.-S, Koth, C.M, Case, D.A, Edwards, A.M, Chazin, W.J, Arrowsmith, C.H.
登録日2001-01-05
公開日2001-09-06
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure and dynamics of yeast elongin C in complex with a von Hippel-Lindau peptide.
J.Mol.Biol., 312, 2001
2LQN
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BU of 2lqn by Molmil
Solution structure of CRKL
分子名称: Crk-like protein
著者Jankowski, W, Saleh, T, Kalodimos, C.
登録日2012-03-09
公開日2012-05-16
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Domain organization differences explain Bcr-Abl's preference for CrkL over CrkII.
Nat.Chem.Biol., 8, 2012
3DFX
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BU of 3dfx by Molmil
Opposite GATA DNA binding
分子名称: DNA (5'-D(*DAP*DAP*DGP*DGP*DTP*DTP*DAP*DTP*DCP*DTP*DCP*DTP*DGP*DAP*DTP*DTP*DTP*DAP*DTP*DC)-3'), DNA (5'-D(*DTP*DTP*DGP*DAP*DTP*DAP*DAP*DAP*DTP*DCP*DAP*DGP*DAP*DGP*DAP*DTP*DAP*DAP*DCP*DC)-3'), Trans-acting T-cell-specific transcription factor GATA-3, ...
著者Bates, D.L, Kim, G.K, Guo, L, Chen, L.
登録日2008-06-12
公開日2008-07-29
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structures of multiple GATA zinc fingers bound to DNA reveal new insights into DNA recognition and self-association by GATA.
J.Mol.Biol., 381, 2008
5EDN
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BU of 5edn by Molmil
Structure of HOXB13-DNA(TCG) complex
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DNA (5'-D(P*GP*GP*AP*CP*CP*TP*CP*GP*TP*AP*AP*AP*AP*CP*AP*CP*AP*AP*C)-3'), DNA (5'-D(P*GP*TP*TP*GP*TP*GP*TP*TP*TP*TP*AP*CP*GP*AP*GP*GP*TP*CP*C)-3'), ...
著者Morgunova, E, Yin, Y, Jolma, A, Popov, A, Taipale, J.
登録日2015-10-21
公開日2016-11-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Two distinct DNA sequences recognized by transcription factors represent enthalpy and entropy optima.
Elife, 7, 2018
2R6M
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BU of 2r6m by Molmil
Crystal structure of rat CK2-beta subunit
分子名称: Casein kinase II subunit beta, ZINC ION
著者Shen, Y.
登録日2007-09-06
公開日2008-09-23
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal structures of catalytic and regulatory subunits of rat protein kinase CK2
CHIN.SCI.BULL., 54, 2009
6INL
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BU of 6inl by Molmil
Crystal structure of CDK2 IN complex with Inhibitor CVT-313
分子名称: 2,2'-{[6-{[(4-methoxyphenyl)methyl]amino}-9-(propan-2-yl)-9H-purin-2-yl]azanediyl}di(ethan-1-ol), Cyclin-dependent kinase 2
著者Talapati, S.R, Krishnamurthy, N.R.
登録日2018-10-25
公開日2019-10-30
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structure of cyclin-dependent kinase 2 (CDK2) in complex with the specific and potent inhibitor CVT-313.
Acta Crystallogr.,Sect.F, 76, 2020
3QWR
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BU of 3qwr by Molmil
Crystal structure of IL-23 in complex with an adnectin
分子名称: ADNECTIN, Interleukin-12 subunit beta, Interleukin-23 subunit alpha, ...
著者Wei, A, Sheriff, S.
登録日2011-02-28
公開日2012-02-01
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Structures of adnectin/protein complexes reveal an expanded binding footprint.
Structure, 20, 2012
2JK1
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BU of 2jk1 by Molmil
Crystal structure of the wild-type HupR receiver domain
分子名称: HYDROGENASE TRANSCRIPTIONAL REGULATORY PROTEIN HUPR1, MAGNESIUM ION
著者Davies, K.M, Lowe, E.D, Venien-Bryan, C, Johnson, L.N.
登録日2008-05-26
公開日2008-11-11
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The Hupr Receiver Domain Crystal Structure in its Nonphospho and Inhibitory Phospho States.
J.Mol.Biol., 385, 2009

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