2MTS

Three-Dimensional Structure and Interaction Studies of Hepatitis C Virus p7 in 1,2-Dihexanoyl-sn-glycero-3-phosphocholine by Solution Nuclear Magnetic Resonance

Summary for 2MTS

• Entry DOI: 10.2210/pdb2mts/pdb
• Related: 2MTR
• NMR Information: BMRB: 25181
• Descriptor: HEPATITIS C VIRUS P7 PROTEIN (1 entity in total)
• Functional Keywords: membrane protein, viroporin, ion channel
• Biological source: Hepatitis C virus
• Cellular location: Core protein p21: Host endoplasmic reticulum membrane ; Single-pass membrane protein . Core protein p19: Virion . Envelope glycoprotein E1: Virion membrane ; Single-pass type I membrane protein . Envelope glycoprotein E2: Virion membrane ; Single-pass type I membrane protein . p7: Host endoplasmic reticulum membrane ; Multi-pass membrane protein . Protease NS2-3: Host endoplasmic reticulum membrane ; Multi-pass membrane protein . Serine protease NS3: Host endoplasmic reticulum membrane ; Peripheral membrane protein . Non-structural protein 4A: Host endoplasmic reticulum membrane ; Single-pass type I membrane protein . Non-structural protein 4B: Host endoplasmic reticulum membrane ; Multi-pass membrane protein . Non-structural protein 5A: Host endoplasmic reticulum membrane ; Peripheral membrane protein . RNA-directed RNA polymerase: Host endoplasmic reticulum membrane ; Single-pass type I membrane protein : O92972
• Total number of polymer chains: 1
• Total formula weight: 6693.92

Authors

Cook, G.A.,Dawson, L.A.,Tian, Y.,Opella, S.J. (deposition date: 2014-08-29, release date: 2014-10-15, Last modification date: 2023-06-14)

• Primary citation: Cook, G.A.,Dawson, L.A.,Tian, Y.,Opella, S.J.; Three-dimensional structure and interaction studies of hepatitis C virus p7 in 1,2-dihexanoyl-sn-glycero-3-phosphocholine by solution nuclear magnetic resonance.; Biochemistry, 52:5295-5303, 2013; PubMed: 23841474; DOI: 10.1021/bi4006623

Experimental method

SOLUTION NMR