4I77
Lebrikizumab Fab bound to IL-13
Summary for 4I77
Entry DOI | 10.2210/pdb4i77/pdb |
Descriptor | Lebrikizumab heavy chain, Lebrikizumab light chain, Interleukin-13, ... (4 entities in total) |
Functional Keywords | immunoglobulin, immune system recognition, immune system-cytokine complex, immune system/cytokine |
Biological source | Homo sapiens More |
Cellular location | Secreted: P35225 |
Total number of polymer chains | 3 |
Total formula weight | 59650.22 |
Authors | Eigenbrot, C.,Ultsch, M. (deposition date: 2012-11-30, release date: 2013-02-06, Last modification date: 2023-09-20) |
Primary citation | Ultsch, M.,Bevers, J.,Nakamura, G.,Vandlen, R.,Kelley, R.F.,Wu, L.C.,Eigenbrot, C. Structural Basis of Signaling Blockade by Anti-IL-13 Antibody Lebrikizumab. J.Mol.Biol., 425:1330-1339, 2013 Cited by PubMed: 23357170DOI: 10.1016/j.jmb.2013.01.024 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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