PDB: 55698 件ウェブページステータス検索Chemie searchBIRD

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7Q4S	Structure of the Pseudomonas aeruginosa bacteriophage JG004 endolysin Pae87, apo form. 分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Endolysin, TETRAETHYLENE GLYCOL 著者 Seoane-Blanco, M, van Raaij, M.J. 登録日 2021-11-02 公開日 2022-02-23 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Monomodular Pseudomonas aeruginosa phage JG004 lysozyme (Pae87) contains a bacterial surface-active antimicrobial peptide-like region and a possible substrate-binding subdomain. Acta Crystallogr D Struct Biol, 78, 2022
7N77	Cryo-EM structure of ATP13A2 D458N/D962N mutant in the AlF-bound E1P-like state 分子名称: CHOLESTEROL HEMISUCCINATE, Isoform 3 of Polyamine-transporting ATPase 13A2, MAGNESIUM ION, ... 著者 Sim, S.I, Park, E. 登録日 2021-06-09 公開日 2021-11-10 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structural basis of polyamine transport by human ATP13A2 (PARK9). Mol.Cell, 81, 2021
7NIC	CryoEM structure of disease related M854K MDA5-dsRNA filament in complex with ADP-AlF4(minor class) 分子名称: ADENOSINE-5'-DIPHOSPHATE, Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*GP*UP*CP*AP*AP*GP*CP*CP*GP*AP*GP*GP*AP*GP*A)-3'), ... 著者 Yu, Q, Modis, Y. 登録日 2021-02-11 公開日 2021-11-17 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 MDA5 disease variant M854K prevents ATP-dependent structural discrimination of viral and cellular RNA. Nat Commun, 12, 2021
7NIQ	CryoEM structure of disease related M854K MDA5-dsRNA filament in complex with ADP-AlF4(Major class) 分子名称: ADENOSINE-5'-DIPHOSPHATE, Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*AP*UP*CP*UP*CP*CP*UP*CP*GP*GP*CP*UP*UP*G)-3'), ... 著者 Yu, Q, Modis, Y. 登録日 2021-02-13 公開日 2021-11-17 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 MDA5 disease variant M854K prevents ATP-dependent structural discrimination of viral and cellular RNA. Nat Commun, 12, 2021
7Q1W	Ruminococcus gnavus ATC29149 endo-beta-1,4-galactosidase (RgGH98) E411A in complex with blood group A (BgA II) tetrasaccharide 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, GLYCEROL, ... 著者 Owen, C.D, Wu, H, Crost, E.H, van Bakel, W, Gascuena, A.M, Latousakis, D, Hicks, T, Walpole, S, Urbanowicz, P.A, Ndeh, D, Monaco, S, Salom, L.S, Griffiths, R, Colvile, A, Spencer, D.I.R, Walsh, M.A, Angulo, J, Juge, N. 登録日 2021-10-21 公開日 2022-03-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 The human gut symbiont Ruminococcus gnavus shows specificity to blood group A antigen during mucin glycan foraging: Implication for niche colonisation in the gastrointestinal tract. Plos Biol., 19, 2021
7PK6	Providencia stuartii Arginine decarboxylase (Adc), stack structure 分子名称: Biodegradative arginine decarboxylase 著者 Jessop, M, Desfosses, A, Bacia-Verloop, M, Gutsche, I. 登録日 2021-08-25 公開日 2022-04-20 実験手法 ELECTRON MICROSCOPY (2.15 Å) 主引用文献 Structural and biochemical characterisation of the Providencia stuartii arginine decarboxylase shows distinct polymerisation and regulation. Commun Biol, 5, 2022
7N36	Crystal structure of wild-type human gamma(S)-crystallin 分子名称: Gamma-crystallin S 著者 Norton-Baker, B, Mehrabi, P, Martin, R.W. 登録日 2021-05-31 公開日 2022-03-23 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Deamidation of the human eye lens protein gamma S-crystallin accelerates oxidative aging. Structure, 30, 2022
7N37	Crystal structure of 3-site deamidated variant of human gamma(S)-crystallin 分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Gamma-crystallin S, MAGNESIUM ION 著者 Norton-Baker, B, Mehrabi, P, Martin, R.W. 登録日 2021-05-31 公開日 2022-03-23 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Deamidation of the human eye lens protein gamma S-crystallin accelerates oxidative aging. Structure, 30, 2022
7N38	Crystal structure of 5-site deamidated variant of human gamma(S)-crystallin 分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Gamma-crystallin S, MAGNESIUM ION 著者 Norton-Baker, B, Mehrabi, P, Martin, R.W. 登録日 2021-05-31 公開日 2022-03-23 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.22 Å) 主引用文献 Deamidation of the human eye lens protein gamma S-crystallin accelerates oxidative aging. Structure, 30, 2022
7N39	Crystal structure of 7-site deamidated variant of human gamma(S)-crystallin 分子名称: Gamma-crystallin S, SULFATE ION 著者 Norton-Baker, B, Mehrabi, P, Martin, R.W. 登録日 2021-05-31 公開日 2022-03-23 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.56 Å) 主引用文献 Deamidation of the human eye lens protein gamma S-crystallin accelerates oxidative aging. Structure, 30, 2022
7N3A	Crystal structure of 9-site deamidated variant of human gamma(S)-crystallin 分子名称: Gamma-crystallin S 著者 Norton-Baker, B, Mehrabi, P, Martin, R.W. 登録日 2021-05-31 公開日 2022-03-23 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Deamidation of the human eye lens protein gamma S-crystallin accelerates oxidative aging. Structure, 30, 2022
7N3B	Crystal structure of aged 9-site deamidated variant of human gamma(S)-crystallin 分子名称: Gamma-crystallin S 著者 Norton-Baker, B, Mehrabi, P, Martin, R.W. 登録日 2021-05-31 公開日 2022-03-23 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Deamidation of the human eye lens protein gamma S-crystallin accelerates oxidative aging. Structure, 30, 2022
7N1S	Crystal Structure Analysis of Xac Nucleotide Pyrophosphatase/Phosphodiesterase 分子名称: Phosphodiesterase-nucleotide pyrophosphatase, TETRAETHYLENE GLYCOL, ZINC ION 著者 Fernandez, D, Li, L, Brown, J.A, Carozza, J.A. 登録日 2021-05-28 公開日 2022-06-01 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 ENPP1's regulation of extracellular cGAMP is a ubiquitous mechanism of attenuating STING signaling. Proc.Natl.Acad.Sci.USA, 119, 2022
5BNV	Crystal structure of Human MCM2 HBD chaperoning a histone H3-H4 tetramer 分子名称: DNA replication licensing factor MCM2, Histone H3.3, Histone H4, ... 著者 Huang, H, Patel, D.J. 登録日 2015-05-26 公開日 2015-06-17 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.795 Å) 主引用文献 A unique binding mode enables MCM2 to chaperone histones H3-H4 at replication forks. Nat.Struct.Mol.Biol., 22, 2015
7PZF	Crystal structure of the OmpK36 TD insertion chimera from Klebsiella pneumonia 分子名称: LITHIUM ION, OmpK36, TETRADECANE 著者 Kwong, H, Beis, K. 登録日 2021-10-12 公開日 2022-07-06 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.499 Å) 主引用文献 Widespread emergence of OmpK36 loop 3 insertions among multidrug-resistant clones of Klebsiella pneumoniae. Plos Pathog., 18, 2022
5EXL	FACTOR XIA IN COMPLEX WITH THE INHIBITOR 4-(aminomethyl)-~{N}-[(1~{S})-1-[4-(3-oxidanyl-1~{H}-indazol-5-yl)pyridin-2-yl]-2-phenyl-ethyl]cyclohexane-1-carboxamide 分子名称: 1,2-ETHANEDIOL, 4-(aminomethyl)-~{N}-[(1~{S})-1-[4-(3-oxidanyl-1~{H}-indazol-5-yl)pyridin-2-yl]-2-phenyl-ethyl]cyclohexane-1-carboxamide, Coagulation factor XIa light chain, ... 著者 Wei, A. 登録日 2015-11-23 公開日 2016-04-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Orally bioavailable pyridine and pyrimidine-based Factor XIa inhibitors: Discovery of the methyl N-phenyl carbamate P2 prime group Bioorg.Med.Chem., 24, 2016
7PVW	Crystal structure of the intertwined dimer of the c-Src SH3 domain E93V-S94A-R95S-T96G-N112G-N113Y-T114N-E115H mutant 分子名称: ACETATE ION, Isoform 1 of Proto-oncogene tyrosine-protein kinase Src, TETRAETHYLENE GLYCOL 著者 Camara-Artigas, A, Salinas Garcia, M.C. 登録日 2021-10-05 公開日 2022-09-14 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 The effect of the hinge loops composition in the domain swapping of the SH3 domain To be published
5EXM	FACTOR XIA IN COMPLEX WITH THE INHIBITOR methyl ~{N}-[4-[2-[(1~{S})-1-[[4-(aminomethyl)cyclohexyl]carbonylamino]-2-phenyl-ethyl]pyridin-4-yl]phenyl]carbamate 分子名称: 1,2-ETHANEDIOL, Coagulation factor XIa light chain, SULFATE ION, ... 著者 Wei, A. 登録日 2015-11-23 公開日 2016-04-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Orally bioavailable pyridine and pyrimidine-based Factor XIa inhibitors: Discovery of the methyl N-phenyl carbamate P2 prime group Bioorg.Med.Chem., 24, 2016
7Q10	Acetyltrasferase(3) type IIIa in complex with 3-N-methyl-nemycin B 分子名称: 3N methyl nemycin B, ACETATE ION, Aminoglycoside N(3)-acetyltransferase III, ... 著者 Pontillo, N, Guskov, A. 登録日 2021-10-17 公開日 2022-11-02 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 3-N-alkylation in aminoglycoside antibiotic neomycin B overcomes bacterial resistance mediated by acetyltransferase (3) IIIa To Be Published
7Q1D	Acetyltrasferase(3) type IIIa in complex with 3-N-methyl-nemycin B 分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Aminoglycoside N(3)-acetyltransferase III, CHLORIDE ION, ... 著者 Pontillo, N, Guskov, A. 登録日 2021-10-18 公開日 2022-11-02 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.43 Å) 主引用文献 3-N-alkylation in aminoglycoside antibiotic neomycin B overcomes bacterial resistance mediated by acetyltransferase (3) IIIa To Be Published
7Q1X	Acetyltrasferase(3) type IIIa in complex with neomycin B 分子名称: Aminoglycoside N(3)-acetyltransferase III, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Pontillo, N, Guskov, A. 登録日 2021-10-21 公開日 2022-11-02 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 The 3-N-alkylation of the neomycin B outmaneuvers the aminoglycoside resistant enzyme acetyltransferase(3)IIIa via an unexpected mechanism To Be Published
7Q0Q	Acetyltrasferase(3) type IIIa in complex with 3-N-methyl-nemycin B 分子名称: 3N methyl nemycin B, ACETATE ION, Aminoglycoside N(3)-acetyltransferase III, ... 著者 Pontillo, N, Guskov, A. 登録日 2021-10-16 公開日 2022-11-02 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 The 3-N-alkylation of the neomycin B outmaneuvers the aminoglycoside resistant enzyme acetyltransferase(3)IIIa via an unexpected mechanism To Be Published
7Q5C	Crystal structure of OmpG in space group 96 分子名称: Outer membrane porin G, SODIUM ION, TETRAETHYLENE GLYCOL, ... 著者 Nguyen, T.T.M, Khan, A.R, Barringer, R, McManus, J.J, Race, P.R. 登録日 2021-11-03 公開日 2022-11-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.717 Å) 主引用文献 Experimental phase diagrams to optimise OmpG To Be Published
5C0C	1E6 TCR in complex with HLA-A02 carrying RQFGPDWIVA 分子名称: 1,2-ETHANEDIOL, 1E6 TCR Alpha Chain, 1E6 TCR Beta Chain, ... 著者 Rizkallah, P.J, Bulek, A.M, Cole, D.K, Sewell, A.K. 登録日 2015-06-12 公開日 2016-05-04 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.974 Å) 主引用文献 Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity. J.Clin.Invest., 126, 2016
7PLJ	Structure of Polyphosphate kinase 2 from Deinococcus radiodurans, in complex with ATP and polyphosphates. 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DI(HYDROXYETHYL)ETHER, ... 著者 Silva, S.T.N, Romao, C.V. 登録日 2021-08-31 公開日 2023-03-22 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Structure of Polyphosphate kinase 2 from Deinococcus radiodurans, in complex with ATP and polyphosphates. To Be Published

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