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7N37

Crystal structure of 3-site deamidated variant of human gamma(S)-crystallin

Summary for 7N37
Entry DOI10.2210/pdb7n37/pdb
DescriptorGamma-crystallin S, MAGNESIUM ION, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (4 entities in total)
Functional Keywordsstructural protein, crystallin, human crystallin, gamma(s) crystallin, eye lens protein
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total formula weight21196.13
Authors
Norton-Baker, B.,Mehrabi, P.,Martin, R.W. (deposition date: 2021-05-31, release date: 2022-03-23, Last modification date: 2023-10-18)
Primary citationNorton-Baker, B.,Mehrabi, P.,Kwok, A.O.,Roskamp, K.W.,Rocha, M.A.,Sprague-Piercy, M.A.,von Stetten, D.,Miller, R.J.D.,Martin, R.W.
Deamidation of the human eye lens protein gamma S-crystallin accelerates oxidative aging.
Structure, 30:763-776.e4, 2022
Cited by
PubMed: 35338852
DOI: 10.1016/j.str.2022.03.002
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.3 Å)
Structure validation

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