7N37
Crystal structure of 3-site deamidated variant of human gamma(S)-crystallin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Gamma-crystallin S | polymer | 178 | 20962.6 | 1 | UniProt (P22914) Pfam (PF00030) | Homo sapiens (Human) | Beta-crystallin S,Gamma-S-crystallin |
| 2 | B (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 3 | C (A) | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 209.2 | 1 | Chemie (BTB) | |||
| 4 | D (A) | water | water | 18.0 | 181 | Chemie (HOH) |
Sequence modifications
A: 2 - 178 (UniProt: P22914)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | expression tag |
| Asp 15 | Asn 15 | engineered mutation |
| Glu 121 | Gln 121 | engineered mutation |
| Asp 144 | Asn 144 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 20962.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 233.5 | |
| All* | Total formula weight | 21196.1 |
