PDB: 71589 件ウェブページステータス検索Chemie searchBIRD

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4V0C	Crystal Structure of the Kv7.1 proximal C-terminal Domain in Complex with Calmodulin 分子名称: CALCIUM ION, CALMODULIN, POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 1, ... 著者 Sachyani, D, Hirsch, J.A. 登録日 2014-09-14 公開日 2014-11-05 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.86 Å) 主引用文献 Structural Basis of a Kv7.1 Potassium Channel Gating Module: Studies of the Intracellular C-Terminal Domain in Complex with Calmodulin. Structure, 22, 2014
5W85	CRYSTAL STRUCTURE OF IRAK-4 WITH A 4,6-DIAMINONICOTINAMIDE INHIBITOR (COMPOUND NUMBER 9) 分子名称: 6-[(1,3-benzothiazol-6-yl)amino]-4-{[(2S)-1-hydroxy-3-phenylpropan-2-yl]amino}-N-methylpyridine-3-carboxamide, Interleukin-1 receptor-associated kinase 4 著者 Sack, J.S. 登録日 2017-06-21 公開日 2017-10-11 最終更新日 2017-10-25 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Discovery and structure-based design of 4,6-diaminonicotinamides as potent and selective IRAK4 inhibitors. Bioorg. Med. Chem. Lett., 27, 2017
5WF0	70S ribosome-EF-Tu H84A complex with GTP and near-cognate tRNA (Complex C2) 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Fislage, M, Frank, J. 登録日 2017-07-11 公開日 2018-05-02 最終更新日 2019-11-20 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-TuH84A. Nucleic Acids Res., 46, 2018
4KV2	Ubiquitin-like domain of the mycobacterium tuberculosis type VII secretion system protein ECCD1 分子名称: ESX-1 secretion system protein eccD1 著者 Korotkov, K.V, Evans, T.J. 登録日 2013-05-22 公開日 2014-04-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Structures of EccB1 and EccD1 from the core complex of the mycobacterial ESX-1 type VII secretion system. Bmc Struct.Biol., 16, 2016
5AA9	Structure of L1198F Mutant Human Anaplastic Lymphoma Kinase in Complex with PF-06463922 ((10R)-7-amino-12-fluoro-2,10,16-trimethyl- 15-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo(4,3-h)(2,5,11) benzoxadiazacyclotetradecine-3-carbonitrile). 分子名称: (10R)-7-amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo[4,3-h][2,5,11]benzoxadiazacyclotetradecine-3-carbonitrile, ALK TYROSINE KINASE RECEPTOR 著者 McTigue, M, Deng, Y.-L, Liu, W, Brooun, A, Stewart, A. 登録日 2015-07-23 公開日 2016-06-08 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Resensitization to Crizotinib by the Lorlatinib Alk Resistance Mutation L1198F. N.Engl.J.Med., 374, 2016
5AAB	Structure of C1156Y,L1198F Mutant Human Anaplastic Lymphoma Kinase in Complex with Crizotinib 分子名称: 3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-yl-1H-pyrazol-4-yl)pyridin-2-amine, ALK TYROSINE KINASE RECEPTOR 著者 McTigue, M, Deng, Y, Liu, W, Brooun, A, Stewart, A. 登録日 2015-07-23 公開日 2016-06-08 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Resensitization to Crizotinib by the Lorlatinib Alk Resistance Mutation L1198F. N.Engl.J.Med., 374, 2016
5WJU	Cryo-EM structure of B. subtilis flagellar filaments A39V, N133H 分子名称: Flagellin 著者 Wang, F, Burrage, A.M, Kearns, D.B, Egelman, E.H. 登録日 2017-07-24 公開日 2017-10-25 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 A structural model of flagellar filament switching across multiple bacterial species. Nat Commun, 8, 2017
5WFK	70S ribosome-EF-Tu H84A complex with GTP and near-cognate tRNA (Complex C3) 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Fislage, M, Frank, J. 登録日 2017-07-12 公開日 2018-05-02 最終更新日 2019-11-20 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-TuH84A. Nucleic Acids Res., 46, 2018
5WJY	Cryo-EM structure of B. subtilis flagellar filaments S285P 分子名称: Flagellin 著者 Wang, F, Burrage, A.M, Kearns, D.B, Egelman, E.H. 登録日 2017-07-24 公開日 2017-10-25 最終更新日 2020-01-01 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 A structural model of flagellar filament switching across multiple bacterial species. Nat Commun, 8, 2017
5AGT	Crystal structure of the LeuRS editing domain of Mycobacterium tuberculosis in complex with the adduct (S)-3-(Aminomethyl)-4-chloro-7-ethoxybenzo[c][1,2]oxaborol-1(3H)-ol-AMP 分子名称: 4-Chloro-3-aminomethyl-7-[ethoxy]-3H-benzo[C][1,2]oxaborol-1-ol modified adenosine, GLYCEROL, LEUCINE--TRNA LIGASE, ... 著者 Palencia, A, Li, X, Alley, M.R.K, Ding, C, Easom, E.E, Hernandez, V, Meewan, M, Mohan, M, Rock, F.L, Franzblau, S.G, Wang, Y, Lenaerts, A.J, Parish, T, Cooper, C.B, Waters, M.G, Ma, Z, Mendoza, A, Barros, D, Cusack, S, Plattner, J.J. 登録日 2015-02-03 公開日 2016-03-02 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Discovery of Novel Oral Protein Synthesis Inhibitors of Mycobacterium Tuberculosis that Target Leucyl-tRNA Synthetase. Antimicrob.Agents Chemother., 60, 2016
5A0Z	STRUCTURE OF CUTC CHOLINE LYASE CHOLINE FREE FORM FROM KLEBSIELLA PNEUMONIAE 分子名称: CHOLINE TRIMETHYLAMINE LYASE 著者 Kalnins, G, Tars, K. 登録日 2015-04-27 公開日 2015-07-29 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structure and Function of Cutc Choline Lyase from Human Microbiota Bacterium Klebsiella Pneumoniaee J.Biol.Chem., 290, 2015
5AB7	Crystal structure of Trypanosoma brucei SCP2-thiolase like protein (TbSLP) in complex with malonyl-CoA. 分子名称: MALONYL-COENZYME A, SCP2-THIOLASE LIKE PROTEIN, SULFATE ION 著者 Harijan, R.K, Kiema, T.R, Wierenga, R.K. 登録日 2015-08-02 公開日 2016-05-04 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The Scp2-Thiolase-Like Protein (Slp) of Trypanosoma Brucei is an Enzyme Involved in Lipid Metabolism. Proteins, 84, 2016
5A05	Crystal structure of aldose-aldose oxidoreductase from Caulobacter crescentus complexed with maltotriose 分子名称: ALDOSE-ALDOSE OXIDOREDUCTASE, MALONATE ION, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... 著者 Taberman, H, Rouvinen, J, Parkkinen, T. 登録日 2015-04-17 公開日 2015-10-21 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.897 Å) 主引用文献 Structure and Function of Caulobacter Crescentus Aldose-Aldose Oxidoreductase. Biochem.J., 472, 2015
4GX9	Crystal structure of a DNA polymerase III alpha-epsilon chimera 分子名称: DNA polymerase III subunit epsilon,DNA polymerase III subunit alpha 著者 Li, N, Horan, N, Xu, Z.-Q, Jacques, D, Dixon, N.E, Oakley, A.J. 登録日 2012-09-04 公開日 2013-04-03 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Proofreading exonuclease on a tether: the complex between the E. coli DNA polymerase III subunits alpha, {varepsilon}, theta and beta reveals a highly flexible arrangement of the proofreading domain Nucleic Acids Res., 41, 2013
2MAR	Solution structure of Ani s 5 Anisakis simplex allergen 分子名称: SXP/RAL-2 family protein 著者 Garcia-Mayoral, M.F, Trevino, M.A, Perez-Pinar, T, Caballero, M.L, Knaute, T, Umpierrez, A, Bruix, M, Rodriguez-Perez, R. 登録日 2013-07-17 公開日 2014-07-02 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Relationships between IgE/IgG4 epitopes, structure and function in Anisakis simplex Ani s 5, a member of the SXP/RAL-2 protein family Plos Negl Trop Dis, 8, 2014
3S55	Crystal structure of a putative short-chain dehydrogenase/reductase from Mycobacterium abscessus bound to NAD 分子名称: CALCIUM ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Putative short-chain dehydrogenase/reductase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2011-05-20 公開日 2011-06-08 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Mycofactocin-associated mycobacterial dehydrogenases with non-exchangeable NAD cofactors. Sci Rep, 7, 2017
3TSC	Crystal structure of short chain dehydrogenase MAP_2410 from Mycobacterium paratuberculosis bound to NAD 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Putative oxidoreductase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2011-09-12 公開日 2011-10-05 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Mycofactocin-associated mycobacterial dehydrogenases with non-exchangeable NAD cofactors. Sci Rep, 7, 2017
1YX8	NMR structure of Calsensin, 20 low energy structures. 分子名称: Calsensin 著者 Venkitaramani, D.V, Fulton, D.B, Andreotti, A.H, Johansen, K.M, Johansen, J. 登録日 2005-02-19 公開日 2005-04-05 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Solution structure and backbone dynamics of Calsensin, an invertebrate neuronal calcium-binding protein. Protein Sci., 14, 2005
3CUR	Structure of a double methionine mutant of NI-FE hydrogenase 分子名称: CARBONMONOXIDE-(DICYANO) IRON, FE3-S4 CLUSTER, GLYCEROL, ... 著者 Volbeda, A. 登録日 2008-04-17 公開日 2008-08-05 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Experimental approaches to kinetics of gas diffusion in hydrogenase Proc.Natl.Acad.Sci.Usa, 105, 2008
1CXR	AUTOMATED 2D NOESY ASSIGNMENT AND STRUCTURE CALCULATION OF CRAMBIN(S22/I25) WITH SELF-CORRECTING DISTANCE GEOMETRY BASED NOAH/DIAMOD PROGRAMS 分子名称: CRAMBIN 著者 Xu, Y, Wu, J, Gorenstein, D, Braun, W. 登録日 1999-08-30 公開日 1999-09-07 最終更新日 2018-03-14 実験手法 SOLUTION NMR 主引用文献 Automated 2D NOESY assignment and structure calculation of Crambin(S22/I25) with the self-correcting distance geometry based NOAH/DIAMOD programs. J.Magn.Reson., 136, 1999
2MP4	Solution Structure of ADF like UNC-60A Protein of Caenorhabditis elegans 分子名称: Actin-depolymerizing factor 1, isoforms a/b 著者 Shukla, V, Yadav, R, Kabra, A, Kumar, D, Ono, S, Arora, A. 登録日 2014-05-11 公開日 2014-06-11 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 NMR Structure and Backbone dynamics of ADF like UNC-60A protein from Caenorhabditis elegans: its divergence from conventional ADF/cofilin To be Published
5HT6	Crystal structure of the SET domain of the human MLL5 methyltransferase 分子名称: Histone-lysine N-methyltransferase 2E 著者 le Maire, A, Mas-y-Mas, S, Dumas, C, Lebedev, A. 登録日 2016-01-26 公開日 2016-11-16 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.093 Å) 主引用文献 The Human Mixed Lineage Leukemia 5 (MLL5), a Sequentially and Structurally Divergent SET Domain-Containing Protein with No Intrinsic Catalytic Activity. Plos One, 11, 2016
3LXN	Structural and Thermodynamic Characterization of the TYK2 and JAK3 Kinase Domains in Complex with CP-690550 and CMP-6 分子名称: 3-{(3R,4R)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}-3-oxopropanenitrile, Non-receptor tyrosine-protein kinase TYK2 著者 Chrencik, J.E, Benson, T.E. 登録日 2010-02-25 公開日 2010-06-02 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural and thermodynamic characterization of the TYK2 and JAK3 kinase domains in complex with CP-690550 and CMP-6. J.Mol.Biol., 400, 2010
3LSV	Structure of the A237F mutant of the pentameric ligand gated ion channel from Gloeobacter Violaceus 分子名称: Ligand-gated ion channel 著者 Nury, H, Corringer, P.J, Delarue, M. 登録日 2010-02-13 公開日 2010-04-28 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 One-microsecond molecular dynamics simulation of channel gating in a nicotinic receptor homologue. Proc.Natl.Acad.Sci.USA, 107, 2010
6DUK	EGFR with an allosteric inhibitor 分子名称: (2R)-2-(5-fluoro-2-hydroxyphenyl)-2-{1-oxo-6-[4-(piperazin-1-yl)phenyl]-1,3-dihydro-2H-isoindol-2-yl}-N-(1,3-thiazol-2-yl)acetamide, Epidermal growth factor receptor, MAGNESIUM ION, ... 著者 Park, E, Eck, M.J. 登録日 2018-06-21 公開日 2019-06-05 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Single and Dual Targeting of Mutant EGFR with an Allosteric Inhibitor. Cancer Discov, 9, 2019

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