PDB: 97138 件ウェブページステータス検索Chemie searchBIRD

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2BQZ	Crystal structure of a ternary complex of the human histone methyltransferase Pr-SET7 (also known as SET8) 分子名称: HISTONE H4, S-ADENOSYL-L-HOMOCYSTEINE, SET8 PROTEIN 著者 Xiao, B, Jing, C, Kelly, G, Walker, P.A, Muskett, F.W, Frenkiel, T.A, Martin, S.R, Sarma, K, Reinberg, D, Gamblin, S.J, Wilson, J.R. 登録日 2005-04-28 公開日 2005-06-08 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Specificity and Mechanism of the Histone Methyltransferase Pr-Set7 Genes Dev., 19, 2005
1STC	CAMP-DEPENDENT PROTEIN KINASE, ALPHA-CATALYTIC SUBUNIT IN COMPLEX WITH STAUROSPORINE 分子名称: CAMP-DEPENDENT PROTEIN KINASE, PROTEIN KINASE INHIBITOR, STAUROSPORINE 著者 Prade, L, Engh, R.A, Girod, A, Kinzel, V, Huber, R, Bossemeyer, D. 登録日 1997-10-10 公開日 1998-02-25 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Staurosporine-induced conformational changes of cAMP-dependent protein kinase catalytic subunit explain inhibitory potential. Structure, 5, 1997
4AMS	A Megaviridae ORFan gene encode a new nucleotidyl transferase 分子名称: MAGNESIUM ION, MG662 著者 Lartigue, A, Claverie, J.M, Priet, S, Abergel, C. 登録日 2012-03-13 公開日 2013-03-20 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 A Megaviridae Orphan Gene Encodes a New Nucleotidyl Transferase To be Published
2HLD	Crystal structure of yeast mitochondrial F1-ATPase 分子名称: ATP synthase alpha chain, mitochondrial, ATP synthase beta chain, ... 著者 Kabaleeswaran, V, Puri, N, Walker, J.E, Leslie, A.G, Mueller, D.M. 登録日 2006-07-06 公開日 2006-11-28 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Novel features of the rotary catalytic mechanism revealed in the structure of yeast F(1) ATPase. Embo J., 25, 2006
6DBP	RNA-recognition motif 1 of human MSI2 分子名称: RNA-binding protein Musashi homolog 2 著者 Goldgur, Y, Kharas, M.G, Minuesa, G. 登録日 2018-05-03 公開日 2019-05-08 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.603 Å) 主引用文献 Small-molecule targeting of MUSASHI RNA-binding activity in acute myeloid leukemia. Nat Commun, 10, 2019
6DHI	Butelase 1: Auto-Catalytic Cleavage as an Evolutionary Constraint for Macrocyclizing Endopeptidases 分子名称: Asparaginyl endopeptidase 著者 Bond, C.S, Haywood, J. 登録日 2018-05-20 公開日 2018-08-15 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 The macrocyclizing protease butelase 1 remains autocatalytic and reveals the structural basis for ligase activity. Plant J., 98, 2019
1J04	Structural mechanism of enzyme mistargeting in hereditary kidney stone disease in vitro 分子名称: (AMINOOXY)ACETIC ACID, GLYCEROL, alanine--glyoxylate aminotransferase 著者 Zhang, X, Djordjevic, S, Bartlam, M, Ye, S, Rao, Z, Danpure, C.J. 登録日 2002-10-30 公開日 2003-11-11 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural implications of a G170R mutation of alanine:glyoxylate aminotransferase that is associated with peroxisome-to-mitochondrion mistargeting. Acta Crystallogr.,Sect.F, 66, 2010
3SRV	Crystal structure of spleen tyrosine kinase (SYK) in complex with a diaminopyrimidine carboxamide inhibitor 分子名称: 2-{[(3R,4R)-3-aminotetrahydro-2H-pyran-4-yl]amino}-4-[(4-methylphenyl)amino]pyrimidine-5-carboxamide, GLYCEROL, Tyrosine-protein kinase SYK 著者 Somers, D.O, Neu, M. 登録日 2011-07-07 公開日 2011-09-21 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Discovery of GSK143, a highly potent, selective and orally efficacious spleen tyrosine kinase inhibitor. Bioorg.Med.Chem.Lett., 21, 2011
1DR1	2.2 ANGSTROMS CRYSTAL STRUCTURE OF CHICKEN LIVER DIHYDROFOLATE REDUCTASE COMPLEXED WITH NADP+ AND BIOPTERIN 分子名称: 7,8-DIHYDROBIOPTERIN, CALCIUM ION, DIHYDROFOLATE REDUCTASE, ... 著者 Mctigue, M.A, Davies /II, J.F, Kaufman, B.T, Xuong, N.-H, Kraut, J. 登録日 1992-03-14 公開日 1993-10-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of chicken liver dihydrofolate reductase complexed with NADP+ and biopterin. Biochemistry, 31, 1992
6DII	Structure of Arabidopsis Fatty Acid Amide Hydrolase in Complex with methyl linolenyl fluorophosphonate 分子名称: Fatty acid amide hydrolase, methyl-9Z,12Z,15Z-octadecatrienylphosphonofluoridate 著者 Aziz, M, Wang, X, Tripathi, A, Bankaitis, V, Chapman, K.D. 登録日 2018-05-23 公開日 2019-03-27 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural analysis of a plant fatty acid amide hydrolase provides insights into the evolutionary diversity of bioactive acylethanolamides. J.Biol.Chem., 294, 2019
3S3V	human dihydrofolate reductase Q35K/N64F double mutant binary complex with trimethoprim 分子名称: Dihydrofolate reductase, SULFATE ION, TRIMETHOPRIM 著者 Cody, V, Pace, J, Piraino, J, Queener, S.F. 登録日 2011-05-18 公開日 2011-09-28 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 Crystallographic analysis reveals a novel second binding site for trimethoprim in active site double mutants of human dihydrofolate reductase. J.Struct.Biol., 176, 2011
6DG5	Structure of a de novo designed Interleukin-2/Interleukin-15 mimetic complex with IL-2Rb and IL-2Rg 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cytokine receptor common subunit gamma, ... 著者 Jude, K.M, Silva, D.-A, Yu, S, Baker, D, Garcia, K.C. 登録日 2018-05-16 公開日 2019-01-16 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.516 Å) 主引用文献 De novo design of potent and selective mimics of IL-2 and IL-15. Nature, 565, 2019
1LPC	HIGH RESOLUTION STRUCTURE OF RECOMBINANT DIANTHIN ANTIVIRAL PROTEIN-POTENT ANTI-HIV AGENT (COMPLEX WITH CYCLIC AMP) 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, DIANTHIN 30 著者 Kurinov, I.V, Rajamohan, F, Uckun, F.M. 登録日 2002-05-07 公開日 2004-05-11 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 High resolution X-ray structure and potent anti-HIV activity of recombinant dianthin antiviral protein. Arzneimittelforschung, 54, 2004
6DHV	Structure of Arabidopsis Fatty Acid Amide Hydrolase 分子名称: Fatty acid amide hydrolase 著者 Aziz, M, Wang, X, Tripathi, A, Bankaitis, V, Chapman, K.D. 登録日 2018-05-21 公開日 2019-03-27 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.099 Å) 主引用文献 Structural analysis of a plant fatty acid amide hydrolase provides insights into the evolutionary diversity of bioactive acylethanolamides. J.Biol.Chem., 294, 2019
6E2H	Crystal structure of human Ash2L (SPRY domain and SDI motif) in complex with full length DPY-30 分子名称: Protein dpy-30 homolog, Set1/Ash2 histone methyltransferase complex subunit ASH2 著者 Joshi, M, Brunzelle, J.S, Couture, J.F. 登録日 2018-07-11 公開日 2018-08-08 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.236 Å) 主引用文献 Structural Analysis of the Ash2L/Dpy-30 Complex Reveals a Heterogeneity in H3K4 Methylation. Structure, 26, 2018
4AMQ	A Megaviridae Orfan gene encodes a new nucleotidyl transferase 分子名称: L544, MAGNESIUM ION, MANGANESE (II) ION 著者 Lartigue, A, Claverie, J.M, Priet, S, Abergel, C. 登録日 2012-03-13 公開日 2013-03-20 実験手法 X-RAY DIFFRACTION (2.17 Å) 主引用文献 A Megaviridae Orphan Gene Encodes a New Nucleotidyl Transferase To be Published
6BXD	Crystal structure of Variable Lymphocyte Receptor 2 (VLR2) 分子名称: 2-{2-[2-2-(METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, SULFATE ION, Variable Lymphocyte Receptor 2 著者 Gunn, R.J, Wilson, I.A, Cooper, M.D, Herrin, B.R. 登録日 2017-12-18 公開日 2018-05-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.103 Å) 主引用文献 VLR Recognition of TLR5 Expands the Molecular Characterization of Protein Antigen Binding by Non-Ig-based Antibodies. J. Mol. Biol., 430, 2018
3ZTP	Orthorhombic crystal form P21212 of the Aquifex aeolicus nucleoside diphosphate kinase 分子名称: GLYCEROL, NUCLEOSIDE DIPHOSPHATE KINASE, SULFATE ION 著者 Boissier, F, Georgescauld, F, Moynie, L, Dupuy, J.-W, Sarger, C, Podar, M, Lascu, I, Giraud, M.-F, Dautant, A. 登録日 2011-07-12 公開日 2012-03-14 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.37 Å) 主引用文献 An Intersubunit Disulfide Bridge Stabilizes the Tetrameric Nucleoside Diphosphate Kinase of Aquifex Aeolicus. Proteins, 80, 2012
3ZTQ	Hexagonal crystal form P61 of the Aquifex aeolicus nucleoside diphosphate kinase 分子名称: NUCLEOSIDE DIPHOSPHATE KINASE 著者 Boissier, F, Georgescauld, F, Moynie, L, Dupuy, J.-W, Sarger, C, Podar, M, Lascu, I, Giraud, M.-F, Dautant, A. 登録日 2011-07-12 公開日 2012-02-29 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 An Inter-Subunit Disulphide Bridge Stabilizes the Tetrameric Nucleoside Diphosphate Kinase of Aquifex Aeolicus Proteins, 80, 2012
6BXE	Crystal structure of Variable Lymphocyte Receptor 9 (VLR9) 分子名称: Variable lymphocyte receptor diversity region 著者 Gunn, R.J, Wilson, I.A, Cooper, M.D, Herrin, B.R. 登録日 2017-12-18 公開日 2018-05-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.651 Å) 主引用文献 VLR Recognition of TLR5 Expands the Molecular Characterization of Protein Antigen Binding by Non-Ig-based Antibodies. J. Mol. Biol., 430, 2018
4BTX	Crystal structure of human vascular adhesion protein-1 in complex with pyridazinone inhibitors 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-isopropylamino-2-phenyl-6-(1H-1,2,4-triazol-5-yl)-3(2H)-pyridazinone, CALCIUM ION, ... 著者 Bligt-Linden, E, Pihlavisto, M, Szatmari, I, Otwinowski, Z, Smith, D.J, Lazar, L, Fulop, F, Salminen, T.A. 登録日 2013-06-19 公開日 2013-12-18 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.78 Å) 主引用文献 Novel Pyridazinone Inhibitors for Vascular Adhesion Protein- 1 (Vap-1): Old Target - New Inhibition Mode. J.Med.Chem., 56, 2013
6CT6	Crystal structure of lactate dehydrogenase from Eimeria maxima with NADH and oxamate 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Lactate dehydrogenase, OXAMIC ACID, ... 著者 Wirth, J.D, Xu, C, Theobald, D.L. 登録日 2018-03-22 公開日 2019-03-27 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.705 Å) 主引用文献 The Mechanistic, Structural, and Evolutionary Origin of Lactate Dehydrogenase Substrate Specificity in Apicomplexa To Be Published
1HD9	The Bowman-Birk Inhibitor Reactive Site Loop Sequence Represents an Independent Structural Beta-Hairpin Motif 分子名称: BOWMAN-BIRK INHIBITOR DERIVED PEPTIDE 著者 Brauer, A.B.E, Kelly, G, McBride, J.D, Cooke, R.M, Matthews, S.J, Leatherbarrow, R.J. 登録日 2000-11-13 公開日 2001-03-29 最終更新日 2023-11-15 実験手法 SOLUTION NMR 主引用文献 The Bowman-Birk Inhibitor Reactive Site Loop Sequence Represents an Independent Structural Beta-Hairpin Motif J.Mol.Biol., 306, 2001
6D24	Trypanosoma cruzi Glucose-6-P Dehydrogenase in complex with G6P 分子名称: 6-O-phosphono-beta-D-glucopyranose, CHLORIDE ION, GLYCEROL, ... 著者 Botti, H, Ortiz, C, Comini, M.A, Larrieux, N, Buschiazzo, A. 登録日 2018-04-12 公開日 2018-05-02 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (3.35 Å) 主引用文献 Glucose-6-Phosphate Dehydrogenase from the Human Pathogen Trypanosoma cruzi Evolved Unique Structural Features to Support Efficient Product Formation. J.Mol.Biol., 431, 2019
6D3I	ftv7 dioxygenase with 2,4-D bound 分子名称: (2,4-DICHLOROPHENOXY)ACETIC ACID, 2-OXOGLUTARIC ACID, COBALT (II) ION, ... 著者 Rydel, T.J, Halls, C.E. 登録日 2018-04-16 公開日 2018-08-15 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3.196 Å) 主引用文献 Development of enzymes for robust aryloxyphenoxypropionate and synthetic auxin herbicide tolerance traits in maize and soybean crops. Pest Manag. Sci., 75, 2019

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