3MJR
 
 | Human dCK complex with Acyclic Nucleoside | 分子名称: | 9-HYROXYETHOXYMETHYLGUANINE, Deoxycytidine kinase, URIDINE-5'-DIPHOSPHATE | 著者 | Hazra, S, Lavie, A. | 登録日 | 2010-04-13 | 公開日 | 2010-07-28 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | The Sugar Ring of the Nucleoside Is Required for Productive Substrate Positioning in the Active Site of Human Deoxycytidine Kinase (dCK): Implications for the Development of dCK-Activated Acyclic Guanine Analogues. J.Med.Chem., 53, 2010
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9QAJ
 
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6BJ7
 
 | Crystal Structure of Purine Nucleoside Phosphorylase Isoform 2 from Schistosoma mansoni in complex with 4-chloro-6-methylpyrimidin-2-amine | 分子名称: | 4-chloro-6-methylpyrimidin-2-amine, DIMETHYL SULFOXIDE, Purine nucleoside phosphorylase | 著者 | Faheem, M, Neto, J.B, Collins, P, Pearce, N.M, Valadares, N.F, Bird, L, Pereira, H.M, Delft, F.V, Barbosa, J.A.R.G. | 登録日 | 2017-11-05 | 公開日 | 2018-11-07 | 最終更新日 | 2024-10-30 | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | 主引用文献 | Crystal Structure of Purine Nucleoside Phosphorylase Isoform 2 from Schistosoma mansoni in complex with 4-chloro-6-methylpyrimidin-2-amine To Be Published
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6BJ6
 
 | Crystal Structure of Purine Nucleoside Phosphorylase Isoform 2 from Schistosoma mansoni in complex with 2-{[(S)-benzenesulfinyl]methyl}benzoic acid | 分子名称: | 2-{[(S)-phenylsulfinyl]methyl}benzoic acid, DIMETHYL SULFOXIDE, Purine nucleoside phosphorylase | 著者 | Faheem, M, Neto, J.B, Collins, P, Pearce, N.M, Valadares, N.F, Bird, L, Pereira, H.M, Delft, F.V, Barbosa, J.A.R.G. | 登録日 | 2017-11-05 | 公開日 | 2018-11-07 | 最終更新日 | 2024-10-23 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | Crystal Structure of Purine Nucleoside Phosphorylase Isoform 2 from Schistosoma mansoni in complex with 2-{[(S)-benzenesulfinyl]methyl}benzoic acid To Be Published
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6LD2
 
 | Zika NS5 polymerase domain | 分子名称: | (1S,2S,4S,5R)-2,4-dimethoxy-5-thiophen-2-yl-cyclohexane-1-carboxylic acid, RNA-directed RNA polymerase NS5, ZINC ION | 著者 | El Sahili, A, Lescar, J. | 登録日 | 2019-11-20 | 公開日 | 2020-08-12 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Non-nucleoside Inhibitors of Zika Virus RNA-Dependent RNA Polymerase. J.Virol., 94, 2020
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6LD1
 
 | Zika NS5 polymerase domain | 分子名称: | 1,2-ETHANEDIOL, RNA-directed RNA polymerase NS5, ZINC ION | 著者 | El Sahili, A, Lescar, J. | 登録日 | 2019-11-20 | 公開日 | 2020-08-12 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Non-nucleoside Inhibitors of Zika Virus RNA-Dependent RNA Polymerase. J.Virol., 94, 2020
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6LD5
 
 | Zika NS5 polymerase domain | 分子名称: | 2,4-dimethoxy-5-thiophen-2-yl-benzoic acid, RNA-directed RNA polymerase NS5, ZINC ION, ... | 著者 | El Sahili, A, Lescar, J. | 登録日 | 2019-11-20 | 公開日 | 2020-08-19 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Non-nucleoside Inhibitors of Zika Virus RNA-Dependent RNA Polymerase. J.Virol., 94, 2020
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6LD4
 
 | Zika NS5 polymerase domain | 分子名称: | 2,4-dimethoxy-5-thiophen-2-yl-benzoic acid, 3-methoxybenzenesulfonamide, RNA-directed RNA polymerase NS5, ... | 著者 | El Sahili, A, Lescar, J. | 登録日 | 2019-11-20 | 公開日 | 2020-08-19 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Non-nucleoside Inhibitors of Zika Virus RNA-Dependent RNA Polymerase. J.Virol., 94, 2020
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6LD3
 
 | Zika NS5 polymerase domain | 分子名称: | 2,4-dimethoxy-5-thiophen-2-yl-benzoic acid, RNA-directed RNA polymerase NS5, ZINC ION, ... | 著者 | El Sahili, A, Lescar, J. | 登録日 | 2019-11-20 | 公開日 | 2020-08-19 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Non-nucleoside Inhibitors of Zika Virus RNA-Dependent RNA Polymerase. J.Virol., 94, 2020
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6YTM
 
 | Human Brd2(BD2) L383V mutant in complex with ET-JQ1-OMe | 分子名称: | (2S)-1-[3-{[(2R)-2-hydroxypropyl]oxy}-2,2-bis({[(2R)-2-hydroxypropyl]oxy}methyl)propoxy]propan-2-ol, Bromodomain-containing protein 2, methyl (2R)-2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.0^{2,6}]trideca-2(6),4,7,10,12-pentaen-9-yl]butanoate | 著者 | Bond, A.G, Ciulli, A, Cowan, A.D. | 登録日 | 2020-04-24 | 公開日 | 2020-05-27 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | 主引用文献 | Stereoselective synthesis of allele-specific BET inhibitors. Org.Biomol.Chem., 18, 2020
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1E2I
 
 | The nucleoside binding site of Herpes simplex type 1 thymidine kinase analyzed by X-ray crystallography | 分子名称: | 9-HYDROXYPROPYLADENINE, R-ISOMER, S-ISOMER, ... | 著者 | Vogt, J, Scapozza, L, Schulz, G.E. | 登録日 | 2000-05-23 | 公開日 | 2000-11-06 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Nucleoside Binding Site of Herpes Simplex Type 1 Thymidine Kinase Analyzed by X-Ray Crystallography Proteins, 41, 2000
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2DXE
 
 | Crystal structure of nucleoside diphosphate kinase in complex with GDP | 分子名称: | CHLORIDE ION, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Kato-Murayama, M, Murayama, K, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2006-08-25 | 公開日 | 2007-02-25 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal structure of nucleoside diphosphate kinase in complex with GDP To be Published
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8UW1
 
 | Cryo-EM structure of DNMT3A1 UDR in complex with H2AK119Ub-nucleosome | 分子名称: | DNA (146-MER), DNA (cytosine-5)-methyltransferase 3A, Histone H2A, ... | 著者 | Gretarsson, K, Abini-Agbomson, S, Armache, K.-J, Lu, C. | 登録日 | 2023-11-05 | 公開日 | 2024-09-11 | 最終更新日 | 2025-05-21 | 実験手法 | ELECTRON MICROSCOPY (2.88 Å) | 主引用文献 | Cancer-associated DNA hypermethylation of Polycomb targets requires DNMT3A dual recognition of histone H2AK119 ubiquitination and the nucleosome acidic patch. Sci Adv, 10, 2024
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1E2J
 
 | The nucleoside binding site of Herpes simplex type 1 thymidine kinase analyzed by X-ray crystallography | 分子名称: | SULFATE ION, THYMIDINE, THYMIDINE KINASE | 著者 | Vogt, J, Scapozza, L, Schulz, G.E. | 登録日 | 2000-05-23 | 公開日 | 2000-11-06 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Nucleoside Binding Site of Herpes Simplex Type 1 Thymidine Kinase Analyzed by X-Ray Crystallography Proteins: Struct.,Funct., Genet., 41, 2000
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1E2H
 
 | The nucleoside binding site of Herpes simplex type 1 thymidine kinase analyzed by X-ray crystallography | 分子名称: | SULFATE ION, THYMIDINE KINASE | 著者 | Vogt, J, Scapozza, L, Schulz, G.E. | 登録日 | 2000-05-23 | 公開日 | 2000-11-06 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Nucleoside Binding Site of Herpes Simplex Type 1 Thymidine Kinase Analyzed by X-Ray Crystallography Proteins: Struct.,Funct., Genet., 41, 2000
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8WG5
 
 | Cryo-EM structure of USP16 bound to H2AK119Ub nucleosome | 分子名称: | DNA (147-MER), Histone H2A type 1-B/E, Histone H2B type 1-K, ... | 著者 | Ai, H.S, He, Z.Z, Deng, Z.H, Liu, L. | 登録日 | 2023-09-20 | 公開日 | 2023-12-27 | 最終更新日 | 2024-11-27 | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | 主引用文献 | Structural and mechanistic basis for nucleosomal H2AK119 deubiquitination by single-subunit deubiquitinase USP16. Nat.Struct.Mol.Biol., 31, 2024
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6BI9
 
 | Crystal Structure of Purine Nucleoside Phosphorylase Isoform 2 from Schistosoma mansoni in complex with 1,2,5-trimethyl-1H-pyrrole-3-carboxylic acid | 分子名称: | 1,2,5-trimethyl-1H-pyrrole-3-carboxylic acid, DIMETHYL SULFOXIDE, Purine nucleoside phosphorylase | 著者 | Faheem, M, Neto, J.B, Collins, P, Pearce, N.M, Valadares, N.F, Bird, L, Pereira, H.M, Delft, F.V, Barbosa, J.A.R.G. | 登録日 | 2017-11-01 | 公開日 | 2018-11-07 | 最終更新日 | 2024-11-20 | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | 主引用文献 | Crystal Structure of Purine Nucleoside Phosphorylase Isoform 2 from Schistosoma mansoni in complex with 1,2,5-trimethyl-1H-pyrrole-3-carboxylic acid To Be Published
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6BI1
 
 | Crystal Structure of Purine Nucleoside Phosphorylase Isoform 2 from Schistosoma mansoni in complex with (2R)-2-amino-3-(benzyloxy)propan-1-ol | 分子名称: | DIMETHYL SULFOXIDE, O-benzyl-L-serine, Purine nucleoside phosphorylase | 著者 | Faheem, M, Neto, J.B, Collins, P, Pearce, N.M, Valadares, N.F, Bird, L, Pereira, H.M, Delft, F.V, Barbosa, J.A.R.G. | 登録日 | 2017-10-31 | 公開日 | 2018-11-07 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | 主引用文献 | Crystal Structure of Purine Nucleoside Phosphorylase Isoform 2 from Schistosoma mansoni in complex with (2R)-2-amino-3-(benzyloxy)propan-1-ol To Be Published
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9II7
 
 | RNA polymerase II elongation complex stalled at SHL(-1) of the nucleosome containing histone variant H2A.B | 分子名称: | DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... | 著者 | Akatsu, M, Kujirai, T, Rina, H, Ehara, H, Takizawa, Y, Sekine, S, Kurumizaka, H. | 登録日 | 2024-06-19 | 公開日 | 2025-06-11 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structural basis of RNAPII transcription on the nucleosome containing histone variant H2A.B. Embo J., 2025
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5GAN
 
 | The overall structure of the yeast spliceosomal U4/U6.U5 tri-snRNP at 3.7 Angstrom | 分子名称: | 13 kDa ribonucleoprotein-associated protein, GUANOSINE-5'-TRIPHOSPHATE, Pre-mRNA-processing factor 31, ... | 著者 | Nguyen, T.H.D, Galej, W.P, Bai, X.C, Oubridge, C, Scheres, S.H.W, Newman, A.J, Nagai, K. | 登録日 | 2015-12-15 | 公開日 | 2016-01-27 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Cryo-EM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 angstrom resolution. Nature, 530, 2016
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2DXD
 
 | Crystal structure of nucleoside diphosphate kinase in complex with ATP analog | 分子名称: | ADENOSINE MONOPHOSPHATE, CHLORIDE ION, Nucleoside diphosphate kinase | 著者 | Kato-Murayama, M, Murayama, K, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2006-08-25 | 公開日 | 2007-02-25 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Crystal structure of nucleoside diphosphate kinase in complex with ATP analog To be Published
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2DYA
 
 | Crystal structure of complex between Adenine nucleotide and nucleoside diphosphate kinase | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, MAGNESIUM ION, ... | 著者 | Kato-Murayama, M, Murayama, K, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2006-09-08 | 公開日 | 2007-03-08 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Crystal structure of complex between Adenine nucleotide and nucleoside diphosphate kinase To be Published
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2DXF
 
 | Crystal structure of nucleoside diphosphate kinase in complex with GTP analog | 分子名称: | CHLORIDE ION, Nucleoside diphosphate kinase, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | 著者 | Kato-Murayama, M, Murayama, K, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2006-08-25 | 公開日 | 2007-02-25 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal structure of nucleoside diphosphate kinase in complex with GTP analog To be Published
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2DY9
 
 | Crystal structure of nucleoside diphosphate kinase in complex with ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, MAGNESIUM ION, ... | 著者 | Kato-Murayama, M, Murayama, K, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2006-09-08 | 公開日 | 2007-03-08 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Crystal structure of nucleoside diphosphate kinase in complex with ADP To be Published
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9OAI
 
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