PDB: 5653 件ウェブページステータス検索Chemie searchBIRD

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4D9J	Structure of a 16 nm protein cage designed by fusing symmetric oligomeric domains 分子名称: Designed 16nm tetrahedral protein cage containing Non-haem bromoperoxidase BPO-A2 and Matrix protein 1 著者 Lai, Y.-T, Cascio, D, Yeates, T.O. 登録日 2012-01-11 公開日 2012-06-20 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.92 Å) 主引用文献 Structure of a 16-nm cage designed by using protein oligomers. Science, 336, 2012
6MQ2	De Novo Design of membrane protein--mini-eVgL membrane protein, C2221 form-2 分子名称: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, mini-eVgL membrane protein 著者 Mravic, M, Liu, L, Degrado, W.F. 登録日 2018-10-09 公開日 2019-04-03 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Packing of apolar side chains enables accurate design of highly stable membrane proteins. Science, 363, 2019
6MPW	De Novo Design of membrane protein--mini-eVgL membrane protein, C2221 form-1 分子名称: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, mini-eVgL membrane protein 著者 Mravic, M, Liu, L, DeGrado, W.F. 登録日 2018-10-08 公開日 2019-04-03 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Packing of apolar side chains enables accurate design of highly stable membrane proteins. Science, 363, 2019
6Z35	De-novo Maquette 2 protein with buried ion-pair 分子名称: Maquette 2-1ip 著者 Baumgart, M, Roepke, M, Muehlbauer, M, Asami, S, Mader, S, Fredriksson, K, Groll, M, Gamiz-Hernandez, A.P, Kaila, V.R.I. 登録日 2020-05-19 公開日 2021-04-07 最終更新日 2024-06-19 実験手法 SOLUTION NMR 主引用文献 Design of buried charged networks in artificial proteins. Nat Commun, 12, 2021
6AJE	Crystal structure of DHODH in complex with ferulenol from Eimeria tenella 分子名称: 4-oxidanyl-3-[(2~{E},6~{E})-3,7,11-trimethyldodeca-2,6,10-trienyl]chromen-2-one, Dihydroorotate dehydrogenase (quinone), mitochondrial, ... 著者 Shiba, T, Inaoka, D.K, Sato, D, Hartuti, E.D, Amalia, E, Nagahama, M, Yoshioka, Y, Matsubayashi, M, Balogun, E.O, Tsuji, N, Kita, K, Harada, S. 登録日 2018-08-27 公開日 2019-08-28 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.65 Å) 主引用文献 Structural and Biochemical Features of Eimeria tenella Dihydroorotate Dehydrogenase, a Potential Drug Target. Genes (Basel), 11, 2020
6VL6	De novo designed tetrahedral nanoparticle T33_dn2 presenting BG505 SOSIP trimers 分子名称: T33_dn2A, T33_dn2B 著者 Ward, A.B, Antanasijevic, A. 登録日 2020-01-22 公開日 2020-08-12 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (4.6 Å) 主引用文献 Targeting HIV Env immunogens to B cell follicles in nonhuman primates through immune complex or protein nanoparticle formulations. NPJ Vaccines, 5, 2020
6OC0	Crystal structure of human DHODH with OSU-03012 分子名称: Dihydroorotate dehydrogenase (quinone), mitochondrial, FLAVIN MONONUCLEOTIDE, ... 著者 Durst, M.A, Lavie, A. 登録日 2019-03-21 公開日 2019-11-13 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Metabolic Modifier Screen Reveals Secondary Targets of Protein Kinase Inhibitors within Nucleotide Metabolism. Cell Chem Biol, 27, 2020
6OC1	Crystal structure of human DHODH with TAK-632 分子名称: Dihydroorotate dehydrogenase (quinone), mitochondrial, FLAVIN MONONUCLEOTIDE, ... 著者 Durst, M.A, Lavie, A. 登録日 2019-03-21 公開日 2019-11-13 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Metabolic Modifier Screen Reveals Secondary Targets of Protein Kinase Inhibitors within Nucleotide Metabolism. Cell Chem Biol, 27, 2020
6VFJ	De novo designed icosahedral nanoparticle I53_dn5 分子名称: I53_dn5A, I53_dn5B 著者 Antanasijevic, A, Ward, A.B. 登録日 2020-01-05 公開日 2020-08-12 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (5.35 Å) 主引用文献 Tailored design of protein nanoparticle scaffolds for multivalent presentation of viral glycoprotein antigens. Elife, 9, 2020
6VFI	De novo designed octahedral nanoparticle O43_dn18 分子名称: O43_dn18A, O43_dn18B 著者 Antanasijevic, A, Ward, A.B. 登録日 2020-01-05 公開日 2020-08-12 最終更新日 2020-08-19 実験手法 ELECTRON MICROSCOPY (4.54 Å) 主引用文献 Tailored design of protein nanoparticle scaffolds for multivalent presentation of viral glycoprotein antigens. Elife, 9, 2020
6AJ5	Crystal structure of ligand-free type DHODH from Eimeria tenella 分子名称: Dihydroorotate dehydrogenase (quinone), mitochondrial, FLAVIN MONONUCLEOTIDE, ... 著者 Shiba, T, Inaoka, D.K, Sato, D, Hartuti, E.D, Amalia, E, Nagahama, M, Yoshioka, Y, Matsubayashi, M, Balogun, E.O, Tsuji, N, Kita, K, Harada, S. 登録日 2018-08-27 公開日 2019-08-28 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Structural and Biochemical Features of Eimeria tenella Dihydroorotate Dehydrogenase, a Potential Drug Target. Genes (Basel), 11, 2020
6VFH	De novo designed tetrahedral nanoparticle T33_dn10 分子名称: T33_dn10A, T33_dn10B 著者 Antanasijevic, A, Ward, A.B. 登録日 2020-01-05 公開日 2020-08-12 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.86 Å) 主引用文献 Tailored design of protein nanoparticle scaffolds for multivalent presentation of viral glycoprotein antigens. Elife, 9, 2020
6QU7	Crystal structure of human DHODH in complex with BAY 2402234 分子名称: ACETATE ION, Dihydroorotate dehydrogenase (quinone), mitochondrial, ... 著者 Friberg, A, Gradl, S. 登録日 2019-02-26 公開日 2019-06-05 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (1.52 Å) 主引用文献 The novel dihydroorotate dehydrogenase (DHODH) inhibitor BAY 2402234 triggers differentiation and is effective in the treatment of myeloid malignancies. Leukemia, 33, 2019
4Z08	Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 1 KE07 design 分子名称: de novo designed kemp eliminase KE07 著者 Jackson, C.J, Hong, N.-S, Carr, P.D. 登録日 2015-03-25 公開日 2016-04-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 1 KE07 design To Be Published
5EYV	Crystal Structure of Adenylosuccinate lyase from Schistosoma mansoni in APO form. 分子名称: Adenylosuccinate lyase 著者 Romanello, L, Torini, J.R, Bird, L.E, Nettleship, J.E, Owens, R.J, Reddivari, Y, Brandao-Neto, J, Pereira, H.M. 登録日 2015-11-25 公開日 2016-11-30 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Structural and kinetic analysis of Schistosoma mansoni Adenylosuccinate Lyase (SmADSL). Mol. Biochem. Parasitol., 214, 2017
5G1N	Aspartate transcarbamoylase domain of human CAD bound to PALA 分子名称: 1,2-ETHANEDIOL, CAD PROTEIN, N-(PHOSPHONACETYL)-L-ASPARTIC ACID 著者 Ruiz-Ramos, A, Grande-Garcia, A, Moreno-Morcillo, M.D, Ramon-Maiques, S. 登録日 2016-03-29 公開日 2016-06-22 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure and Functional Characterization of Human Aspartate Transcarbamoylase, the Target of the Anti-Tumoral Drug Pala. Structure, 24, 2016
5G1O	Aspartate transcarbamoylase domain of human CAD in apo form 分子名称: 1,2-ETHANEDIOL, CAD protein, GLYCEROL 著者 Ruiz-Ramos, A, Grande-Garcia, A, Moreno-Morcillo, M.D, Ramon-Maiques, S. 登録日 2016-03-29 公開日 2016-06-22 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure and Functional Characterization of Human Aspartate Transcarbamoylase, the Target of the Anti-Tumoral Drug Pala. Structure, 24, 2016
5EYT	Crystal Structure of Adenylosuccinate Lyase from Schistosoma mansoni in complex with AMP 分子名称: ADENOSINE MONOPHOSPHATE, Adenylosuccinate lyase 著者 Romanello, L, Torini, J.R, Bird, L, Nettleship, J, Owens, R, Reddivari, Y, Brandao-Neto, J, Pereira, H.M. 登録日 2015-11-25 公開日 2016-11-30 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.3649 Å) 主引用文献 Structural and kinetic analysis of Schistosoma mansoni Adenylosuccinate Lyase (SmADSL). Mol. Biochem. Parasitol., 214, 2017
5G1P	Aspartate transcarbamoylase domain of human CAD bound to carbamoyl phosphate 分子名称: CAD PROTEIN, PHOSPHORIC ACID MONO(FORMAMIDE)ESTER 著者 Ruiz-Ramos, A, Grande-Garcia, A, Moreno-Morcillo, M.D, Ramon-Maiques, S. 登録日 2016-03-29 公開日 2016-06-22 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.19 Å) 主引用文献 Structure and Functional Characterization of Human Aspartate Transcarbamoylase, the Target of the Anti-Tumoral Drug Pala. Structure, 24, 2016
6IDJ	Crystal structure of human DHODH in complex with ferulenol 分子名称: 4-oxidanyl-3-[(2~{E},6~{E})-3,7,11-trimethyldodeca-2,6,10-trienyl]chromen-2-one, ACETATE ION, Dihydroorotate dehydrogenase (quinone), ... 著者 Shiba, T, Inaoka, D.K, Sato, D, Hartuti, E.D, Amalia, E, Nagahama, M, Yoshioka, Y, Matsubayashi, M, Balogun, E.O, Tsuji, N, Kita, K, Harada, S. 登録日 2018-09-10 公開日 2019-09-11 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural and Biochemical Features of Eimeria tenella Dihydroorotate Dehydrogenase, a Potential Drug Target. Genes (Basel), 11, 2020
5ILQ	Crystal structure of truncated unliganded Aspartate Transcarbamoylase from Plasmodium falciparum 分子名称: Aspartate carbamoyltransferase, GLYCEROL, SULFATE ION 著者 Lunev, S, Bosch, S.S, Batista, F.D.A, Wrenger, C, Groves, M.R. 登録日 2016-03-04 公開日 2016-06-08 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of truncated aspartate transcarbamoylase from Plasmodium falciparum. Acta Crystallogr.,Sect.F, 72, 2016
6YPO	Arabidopsis aspartate transcarbamoylase bound to UMP 分子名称: GLYCEROL, PYRB, URIDINE-5'-MONOPHOSPHATE 著者 Ramon Maiques, S, Del Cano Ochoa, F, Bellin, L, Mohlmann, T. 登録日 2020-04-16 公開日 2021-03-03 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 Mechanisms of feedback inhibition and sequential firing of active sites in plant aspartate transcarbamoylase. Nat Commun, 12, 2021
6YS6	Arabidopsis aspartate transcarbamoylase complex with PALA 分子名称: GLYCEROL, N-(PHOSPHONACETYL)-L-ASPARTIC ACID, PYRB, ... 著者 Ramon Maiques, S, Del Cano Ochoa, F, Bellin, L, Mohlmann, T. 登録日 2020-04-21 公開日 2021-03-03 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Mechanisms of feedback inhibition and sequential firing of active sites in plant aspartate transcarbamoylase. Nat Commun, 12, 2021
6YSP	Arabidopsis aspartate transcarbamoylase complex with PALA and carbamoyl phosphate 分子名称: GLYCEROL, N-(PHOSPHONACETYL)-L-ASPARTIC ACID, PHOSPHORIC ACID MONO(FORMAMIDE)ESTER, ... 著者 Ramon Maiques, S, Del Cano Ochoa, F, Bellin, L, Mohlmann, T. 登録日 2020-04-23 公開日 2021-03-03 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.38 Å) 主引用文献 Mechanisms of feedback inhibition and sequential firing of active sites in plant aspartate transcarbamoylase. Nat Commun, 12, 2021
6YW9	Arabidopsis aspartate transcarbamoylase mutant F161A complex with PALA 分子名称: GLYCEROL, N-(PHOSPHONACETYL)-L-ASPARTIC ACID, PYRB 著者 Ramon Maiques, S, Del Cano Ochoa, F, Bellin, L, Mohlmann, T. 登録日 2020-04-29 公開日 2021-03-03 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 Mechanisms of feedback inhibition and sequential firing of active sites in plant aspartate transcarbamoylase. Nat Commun, 12, 2021

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