6IDJ

Crystal structure of human DHODH in complex with ferulenol

Summary for 6IDJ

DescriptorDihydroorotate dehydrogenase (quinone), mitochondrial, SULFATE ION, ACETATE ION, ... (7 entities in total)
Functional Keywordscoccidium, mitochondria, electron transport chain, dihydroorotate dehydrogenase, membrane protein
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total molecular weight44080.67
Authors
Primary citation
Shiba, T.,Inaoka, D.K.,Sato, D.,Hartuti, E.D.,Amalia, E.,Nagahama, M.,Yoshioka, Y.,Matsubayashi, M.,Balogun, E.O.,Tsuji, N.,Kita, K.,Harada, S.
Structural and functional features of Eimeria tenella dihydroorotate dehydrogenase, a potential drug target
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.9 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.18920 2.0% 5.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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PDB entries from 2020-07-29