6VL6

De novo designed tetrahedral nanoparticle T33_dn2 presenting BG505 SOSIP trimers

Summary for 6VL6

Entry DOI	10.2210/pdb6vl6/pdb
EMDB information	21231
Descriptor	T33_dn2A, T33_dn2B (2 entities in total)
Functional Keywords	hiv env, de novo, nanoparticles, vaccine design, de novo protein
Biological source	synthetic construct More
Total number of polymer chains	24
Total formula weight	348506.82
Authors	Ward, A.B.,Antanasijevic, A. (deposition date: 2020-01-22, release date: 2020-08-12, Last modification date: 2024-03-06)
Primary citation	Martin, J.T.,Cottrell, C.A.,Antanasijevic, A.,Carnathan, D.G.,Cossette, B.J.,Enemuo, C.A.,Gebru, E.H.,Choe, Y.,Viviano, F.,Fischinger, S.,Tokatlian, T.,Cirelli, K.M.,Ueda, G.,Copps, J.,Schiffner, T.,Menis, S.,Alter, G.,Schief, W.R.,Crotty, S.,King, N.P.,Baker, D.,Silvestri, G.,Ward, A.B.,Irvine, D.J. Targeting HIV Env immunogens to B cell follicles in nonhuman primates through immune complex or protein nanoparticle formulations. NPJ Vaccines, 5:72-72, 2020 Cited by PubMed: 32802411 DOI: 10.1038/s41541-020-00223-1 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4.6 Å)

Structure validation