5G1P
Aspartate transcarbamoylase domain of human CAD bound to carbamoyl phosphate
Summary for 5G1P
Entry DOI | 10.2210/pdb5g1p/pdb |
Related | 5G1N 5G1O |
Descriptor | CAD PROTEIN, PHOSPHORIC ACID MONO(FORMAMIDE)ESTER (3 entities in total) |
Functional Keywords | transferase, de novo pyrimidine synthesis, transcarbamoylase, transcarbamylase, cad, carbamoyl phosphate synthetase, dihydroorotase, cooperativity |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Cytoplasm : P27708 |
Total number of polymer chains | 6 |
Total formula weight | 210314.65 |
Authors | Ruiz-Ramos, A.,Grande-Garcia, A.,Moreno-Morcillo, M.D.,Ramon-Maiques, S. (deposition date: 2016-03-29, release date: 2016-06-22, Last modification date: 2024-01-10) |
Primary citation | Ruiz-Ramos, A.,Velazquez-Campoy, A.,Grande-Garcia, A.,Moreno-Morcillo, M.,Ramon-Maiques, S. Structure and Functional Characterization of Human Aspartate Transcarbamoylase, the Target of the Anti-Tumoral Drug Pala. Structure, 24:1081-, 2016 Cited by PubMed: 27265852DOI: 10.1016/J.STR.2016.05.001 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.19 Å) |
Structure validation
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