PDB: 30476 件ウェブページステータス検索Chemie searchBIRD

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5JOD	Structure of proplasmepsin IV from Plasmodium falciparum 分子名称: GLYCEROL, Proplasmepsin IV 著者 Recacha, R, Akopjana, I, Tars, K, Jaudzems, K. 登録日 2016-05-02 公開日 2016-08-17 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.528 Å) 主引用文献 Crystal structure of Plasmodium falciparum proplasmepsin IV: the plasticity of proplasmepsins. Acta Crystallogr.,Sect.F, 72, 2016
5JOY	Bacteroides ovatus Xyloglucan PUL GH43A in complex with AraLOG 分子名称: (Z)-L-Arabinonhydroximo-1,4-lactone, 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... 著者 Thompson, A.J, Hemsworth, G.R, Stepper, J, Sobala, L.F, Coyle, T, Larsbrink, J, Spadiut, O, Stubbs, K.A, Brumer, H, Davies, G.J. 登録日 2016-05-03 公開日 2016-08-10 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural dissection of a complex Bacteroides ovatus gene locus conferring xyloglucan metabolism in the human gut. Open Biology, 6, 2016
8GIJ	TEM-1 Beta Lactamase Variant 80.b 分子名称: TEM-1 Beta Lactmase Variant 80.b 著者 Fram, B.F, Gauthier, N.P, Khan, A, Sander, C. 登録日 2023-03-14 公開日 2024-04-17 最終更新日 2024-07-17 実験手法 X-RAY DIFFRACTION (1.59 Å) 主引用文献 Simultaneous enhancement of multiple functional properties using evolution-informed protein design. Nat Commun, 15, 2024
5K78	Dbr1 in complex with 16-mer branched RNA 分子名称: FE (II) ION, RNA lariat debranching enzyme, putative, ... 著者 Clark, N.E, Taylor, A.B, Hart, P.J. 登録日 2016-05-25 公開日 2016-12-07 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.64 Å) 主引用文献 The RNA lariat debranching enzyme Dbr1: metal dependence and branched RNA co-crystal structures Proc.Natl.Acad.Sci.USA, 2016
7WZO	Crystal structure of the SARS-CoV-2 nucleocapsid protein N-terminal domain in complex with Ubl1 分子名称: Nucleoprotein, nsp3 著者 Ni, X.C, Zhou, R.J, Lei, J. 登録日 2022-02-18 公開日 2023-02-01 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.64 Å) 主引用文献 Structural insights into ribonucleoprotein dissociation by nucleocapsid protein interacting with non-structural protein 3 in SARS-CoV-2. Commun Biol, 6, 2023
8GII	TEM-1 Beta Lactamase Variant 80.a 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, TEM-1 Variant 80.a 著者 Fram, B.F, Gauthier, N.P, Khan, A.R, Sander, C. 登録日 2023-03-14 公開日 2024-04-17 最終更新日 2024-07-17 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Simultaneous enhancement of multiple functional properties using evolution-informed protein design. Nat Commun, 15, 2024
8GIR	Structure of Ternary Complex of mouse cGAS with dsDNA and Bound ATP: with 10mM Mg2+ and 0.2mM Mn2+ 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, MANGANESE (II) ION, ... 著者 Wu, S, Sohn, J. 登録日 2023-03-14 公開日 2024-04-17 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
8GIS	Structure of Ternary Complex of mouse cGAS with dsDNA and Bound ATP: with 10mM Mg2+ and 0.5mM Mn2+ 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, MANGANESE (II) ION, ... 著者 Wu, S, Sohn, J. 登録日 2023-03-14 公開日 2024-04-17 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.46 Å) 主引用文献 The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
8GIO	Structure of Ternary Complex of mouse cGAS with dsDNA and Bound ATP: with 10mM Mg2+ and 0.1mM Mn2+ 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, MANGANESE (II) ION, ... 著者 Wu, S, Sohn, J. 登録日 2023-03-14 公開日 2024-04-17 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.67 Å) 主引用文献 The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
5JRL	Crystal Structure of the Sphingopyxin I Lasso Peptide Isopeptidase SpI-IsoP (Native) 分子名称: Dipeptidyl aminopeptidases/acylaminoacyl-peptidases-like protein 著者 Fage, C.D, Hegemann, J.D, Bange, G, Marahiel, M.A. 登録日 2016-05-06 公開日 2016-09-14 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structure and Mechanism of the Sphingopyxin I Lasso Peptide Isopeptidase. Angew.Chem.Int.Ed.Engl., 55, 2016
8GBK	Dri1 hemoprotein variant H79A-R90A with a zinc-mirror heme site 分子名称: HEME B/C, Ssr1698 protein 著者 Yee, E.F, Blaby-Haas, C. 登録日 2023-02-26 公開日 2024-04-24 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 A hemoprotein with a zinc-mirror heme site ties heme availability to carbon metabolism in cyanobacteria. Nat Commun, 15, 2024
5KAW	The structure of SAV2435 bound to TETRAPHENYLPHOSPHONIUM and RHODAMINE 6G 分子名称: GLYCEROL, RHODAMINE 6G, SA2223 protein, ... 著者 Moreno, A, Wade, H. 登録日 2016-06-02 公開日 2016-08-24 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Solution Binding and Structural Analyses Reveal Potential Multidrug Resistance Functions for SAV2435 and CTR107 and Other GyrI-like Proteins. Biochemistry, 55, 2016
5JSM	BRAFV600E Kinase Domain In Complex with Chemically Linked Vemurafenib Inhibitor VEM-3-VEM 分子名称: BENZAMIDINE, CHLORIDE ION, DIMETHYL SULFOXIDE, ... 著者 Grasso, M.J, Marmorstein, R. 登録日 2016-05-08 公開日 2016-09-14 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.19 Å) 主引用文献 Chemically Linked Vemurafenib Inhibitors Promote an Inactive BRAF(V600E) Conformation. Acs Chem.Biol., 11, 2016
8GIM	Structure of Ternary Complex of mouse cGAS with dsDNA and Bound ATP: with 10mM Mg2+ 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, MAGNESIUM ION, ... 著者 Wu, S, Sohn, J. 登録日 2023-03-14 公開日 2024-05-22 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.63 Å) 主引用文献 The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
8GIP	Structure of Ternary Complex of mouse cGAS with dsDNA and Bound ATP: with 10mM Mg2+ and 0.040mM Mn2+ 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, MAGNESIUM ION, ... 著者 Wu, S, Sohn, J. 登録日 2023-03-14 公開日 2024-05-22 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
8GIN	Structure of Ternary Complex of mouse cGAS with dsDNA and Bound ATP: with 10mM Mg2+ and 0.015mM Mn2+ 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, MAGNESIUM ION, ... 著者 Wu, S, Sohn, J. 登録日 2023-03-14 公開日 2024-05-22 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
5JT4	L16A mutant of cytochrome c prime from Alcaligenes xylosoxidans: Ferrous state 分子名称: ASCORBIC ACID, Cytochrome c', HEME C, ... 著者 Kekilli, D, Strange, R.W, Hough, M.A. 登録日 2016-05-09 公開日 2017-03-08 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Engineering proximal vs. distal heme-NO coordination via dinitrosyl dynamics: implications for NO sensor design. Chem Sci, 8, 2017
5KC1	Structure of the C-terminal dimerization domain of Atg38 分子名称: 1,2-ETHANEDIOL, AMMONIUM ION, Autophagy-related protein 38, ... 著者 Ohashi, Y, Soler, N, Garcia-Ortegon, M, Zhang, L, Perisic, O, Masson, G.R, Johnson, C.M, Williams, R.J. 登録日 2016-06-04 公開日 2016-10-05 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Characterization of Atg38 and NRBF2, a fifth subunit of the autophagic Vps34/PIK3C3 complex. Autophagy, 12, 2016
5KDZ	The crystal structure of the T252A mutant of CYP199A4 in complex with 4-methoxybenzoate 分子名称: 4-METHOXYBENZOIC ACID, CHLORIDE ION, Cytochrome P450, ... 著者 Coleman, T, Bruning, J.B, Bell, S.G. 登録日 2016-06-08 公開日 2018-02-07 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.424 Å) 主引用文献 The crystal structure of the T252A mutant of CYP199A4 in complex with 4-methoxybenzoate To Be Published
7XP7	Crystal Structure of the Flavoprotein ColB1 Catalyzing Assembly Line-Tethered Cysteine Dehydrogenation 分子名称: Cyclohexanecarboxyl-CoA dehydrogenase, FLAVIN-ADENINE DINUCLEOTIDE 著者 Ma, X.Y, Tang, Z.J, Liu, W, Ma, M. 登録日 2022-05-03 公開日 2023-02-08 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structure-Based Mechanistic Insights into ColB1, a Flavoprotein Functioning in-trans in the 2,2'-Bipyridine Assembly Line for Cysteine Dehydrogenation. Acs Chem.Biol., 18, 2023
7XHQ	Small-molecule Allosteric Regulation Mechanism of SHP2 分子名称: 2-[(3S,4R)-4-azanyl-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl]-5-[2,3-bis(chloranyl)phenyl]-3-methyl-pyrrolo[2,1-f][1,2,4]triazin-4-one, Tyrosine-protein phosphatase non-receptor type 11 著者 Luo, Y, Zhu, J, Yu, K, Liu, B. 登録日 2022-04-09 公開日 2023-02-15 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Discovery of the SHP2 allosteric inhibitor 2-((3R,4R)-4-amino-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl)-5-(2,3-dichlorophenyl)-3-methylpyrrolo[2,1-f][1,2,4] triazin-4(3H)-one. J Enzyme Inhib Med Chem, 38, 2023
7WW0	The crystal structure of FinI complex with SAH 分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, ... 著者 Zhou, J, Lu, J. 登録日 2022-02-12 公開日 2023-02-15 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 The crystal structure of FinI complex with SAH To Be Published
7WUZ	Structural study of the complex of cblC methylmalonic aciduria and homocysteinuria-related protein MMACHC with cyanocobalamin 分子名称: CYANOCOBALAMIN, Cyanocobalamin reductase / alkylcobalamin dealkylase, L(+)-TARTARIC ACID, ... 著者 Feng, Y, Qin, X. 登録日 2022-02-09 公開日 2023-02-15 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Structural study of the complex of cblC methylmalonic aciduria and homocysteinuria-related protein MMACHC with cyanocobalamin To Be Published
8HTR	Crystal structure of Bcl2 in complex with S-9c 分子名称: 4-[4-[(2~{S})-2-(2-chlorophenyl)pyrrolidin-1-yl]phenyl]-~{N}-[3-nitro-4-(oxan-4-ylmethylamino)phenyl]sulfonyl-2-(1~{H}-pyrrolo[2,3-b]pyridin-5-yloxy)benzamide, Apoptosis regulator Bcl-2 著者 Liu, J, Xu, M, Feng, Y, Liu, Y. 登録日 2022-12-21 公開日 2024-05-15 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Discovery of the Clinical Candidate Sonrotoclax (BGB-11417), a Highly Potent and Selective Inhibitor for Both WT and G101V Mutant Bcl-2. J.Med.Chem., 67, 2024
7WUY	The crystal structure of FinI in complex with SAM and fischerin 分子名称: 1,2-ETHANEDIOL, 3-[[(1~{S},2~{R},4~{a}~{S},8~{a}~{S})-2-methyl-1,2,4~{a},5,6,7,8,8~{a}-octahydronaphthalen-1-yl]carbonyl]-5-[(1~{S},2~{R},5~{S},6~{S})-2,5-bis(oxidanyl)-7-oxabicyclo[4.1.0]heptan-2-yl]-4-oxidanyl-1~{H}-pyridin-2-one, DI(HYDROXYETHYL)ETHER, ... 著者 Zhou, J, Lu, J. 登録日 2022-02-09 公開日 2023-02-15 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 The crystal structure of FinI in complex with SAM and fischerin To Be Published

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