PDB: 17012 件ウェブページステータス検索Chemie searchBIRD

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1SE0	Crystal structure of DIAP1 BIR1 bound to a Grim peptide 分子名称: Apoptosis 1 inhibitor, Cell death protein Grim, ZINC ION 著者 Yan, N, Wu, J.W, Shi, Y. 登録日 2004-02-15 公開日 2004-04-27 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Molecular mechanisms of DrICE inhibition by DIAP1 and removal of inhibition by Reaper, Hid and Grim. Nat.Struct.Mol.Biol., 11, 2004
1S5I	Fab (LNKB-2) of monoclonal antibody to Human Interleukin-2, crystal structure 分子名称: Fab-fragment of monoclonal antibody 著者 Pletnev, V.Z, Goryacheva, E.A, Tsygannik, I.N, Nesmeyanov, V.A, Pletnev, S.V, Pangborn, W, Duax, W. 登録日 2004-01-21 公開日 2004-05-25 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 [A new crystal form of the Fab fragment of a monoclonal antibody to human interleukin-2: the three-dimensional structure at 2.7 A resolution]. Bioorg. Khim., 30
5U2E	BRD4 first bromodomain (BD1) in complex with dual PI3 kinase (PI3K) inhibitor SF2535 分子名称: Bromodomain-containing protein 4, ethyl 4-[5-(morpholin-4-yl)-7-oxo-7H-thieno[3,2-b]pyran-3-yl]benzoate 著者 Andrews, F.H, Kutateladze, T.G. 登録日 2016-11-30 公開日 2017-02-08 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.991 Å) 主引用文献 Dual-activity PI3K-BRD4 inhibitor for the orthogonal inhibition of MYC to block tumor growth and metastasis. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
3KJP	Crystal Structure of hPOT1V2-GGTTAGGGTTAG 分子名称: 5'-D(*G*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*G)-3', Protection of telomeres protein 1 著者 Nandakumar, J, Cech, T.R, Podell, E.R. 登録日 2009-11-03 公開日 2010-01-19 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 How telomeric protein POT1 avoids RNA to achieve specificity for single-stranded DNA. Proc.Natl.Acad.Sci.USA, 107, 2010
4Y2G	Structure of BRCA1 BRCT domains in complex with Abraxas single phosphorylated peptide 分子名称: BRCA1-A complex subunit Abraxas, Breast cancer type 1 susceptibility protein 著者 Wu, Q, Blundell, T.L. 登録日 2015-02-09 公開日 2016-01-27 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure of BRCA1-BRCT/Abraxas Complex Reveals Phosphorylation-Dependent BRCT Dimerization at DNA Damage Sites. Mol.Cell, 61, 2016
1SH6	Crystal structure of actin-binding domain of mouse plectin 分子名称: Plectin 1 著者 Sevcik, J, Urbanikova, L. 登録日 2004-02-25 公開日 2004-05-25 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Actin-binding domain of mouse plectin: crystal structure and binding to vimentin Eur.J.Biochem., 271, 2004
5JH5	Structural Basis for the Hierarchical Assembly of the Core of PRC1.1 分子名称: BCL-6 corepressor-like protein 1, Lysine-specific demethylase 2B, Polycomb group RING finger protein 1, ... 著者 Wong, S.J, Taylor, A.B, Hart, P.J, Kim, C.A. 登録日 2016-04-20 公開日 2016-09-14 最終更新日 2016-10-19 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 KDM2B Recruitment of the Polycomb Group Complex, PRC1.1, Requires Cooperation between PCGF1 and BCORL1. Structure, 24, 2016
4XUS	Crystal structure of the pre-catalytic ternary complex of DNA polymerase lambda with a templating A and an incoming dTTP 分子名称: 2',3'-DIDEOXYCYTIDINE-5'-MONOPHOSPHATE, DNA (5'-D(*CP*AP*GP*TP*A)-3'), DNA (5'-D(*CP*GP*GP*CP*AP*GP*TP*AP*CP*TP*G)-3'), ... 著者 Burak, M.J, Guja, K.E, Garcia-Diaz, M. 登録日 2015-01-26 公開日 2016-02-03 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Nucleotide binding interactions modulate dNTP selectivity and facilitate 8-oxo-dGTP incorporation by DNA polymerase lambda. Nucleic Acids Res., 43, 2015
5TWV	Cryo-EM structure of the pancreatic ATP-sensitive K+ channel SUR1/Kir6.2 in the presence of ATP and glibenclamide 分子名称: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ATP-sensitive inward rectifier potassium channel 11 著者 Martin, G.M, Yoshioka, C, Chen, J.Z, Shyng, S.L. 登録日 2016-11-14 公開日 2017-01-25 最終更新日 2019-12-25 実験手法 ELECTRON MICROSCOPY (6.3 Å) 主引用文献 Cryo-EM structure of the ATP-sensitive potassium channel illuminates mechanisms of assembly and gating. Elife, 6, 2017
5J2B	Ternary complex crystal structure of DNA polymerase Beta with A:C mismatch at the primer terminus 分子名称: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CHLORIDE ION, DNA polymerase beta, ... 著者 Batra, V.K, Wilson, S.H. 登録日 2016-03-29 公開日 2016-10-26 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structures of DNA Polymerase Mispaired DNA Termini Transitioning to Pre-catalytic Complexes Support an Induced-Fit Fidelity Mechanism. Structure, 24, 2016
3KEH	Crystal Structure of N370S Glucocerebrosidase mutant at pH 7.4 分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Wei, R.R, Boucher, S, Pan, C.Q, Edmunds, T. 登録日 2009-10-26 公開日 2010-10-27 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal Structure of Glucocerebrosidase Containing the N370S mutation: Implication on Chaperon Therapy To be Published
5J2H	Ternary complex crystal structure of DNA polymerase Beta with G:T mismatch at the primer terminus 分子名称: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CHLORIDE ION, DNA polymerase beta, ... 著者 Batra, V.K, Wilson, S.H. 登録日 2016-03-29 公開日 2016-10-26 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structures of DNA Polymerase Mispaired DNA Termini Transitioning to Pre-catalytic Complexes Support an Induced-Fit Fidelity Mechanism. Structure, 24, 2016
5J2R	Solution structure of Ras Binding Domain (RBD) of B-Raf 分子名称: N-[2-methoxy-5-({[(E)-2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonyl}methyl)phenyl]glycine, Serine/threonine-protein kinase B-raf 著者 Dutta, K, Vasquez-Del Carpio, R, Aggarwal, A.K, Reddy, E.P. 登録日 2016-03-29 公開日 2016-05-04 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 A Small Molecule RAS-Mimetic Disrupts RAS Association with Effector Proteins to Block Signaling. Cell, 165, 2016
5JJA	Crystal structure of a PP2A B56gamma/BubR1 complex 分子名称: Mitotic checkpoint serine/threonine-protein kinase BUB1 beta, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform 著者 Wang, Z, Wang, J, Rao, Z, Xu, W. 登録日 2016-04-22 公開日 2016-07-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Crystal structure of a PP2A B56-BubR1 complex and its implications for PP2A substrate recruitment and localization. Protein Cell, 7, 2016
4Y17	SdiA in complex with 3-oxo-C8-homoserine lactone 分子名称: 3-OXO-OCTANOIC ACID (2-OXO-TETRAHYDRO-FURAN-3-YL)-AMIDE, Transcriptional regulator of ftsQAZ gene cluster 著者 Nguyen, N.X, Nguyen, Y, Sperandio, V, Jiang, Y. 登録日 2015-02-06 公開日 2015-04-08 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.84 Å) 主引用文献 Structural and Mechanistic Roles of Novel Chemical Ligands on the SdiA Quorum-Sensing Transcription Regulator. Mbio, 6, 2015
5U4Y	IgG Fc bound to 3 helix of the B-domain from Protein A 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, IgG1 fc, Immunoglobulin G-binding protein A, ... 著者 Ultsch, M.H, Eigenbrot, C. 登録日 2016-12-06 公開日 2017-05-17 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.4994 Å) 主引用文献 3-2-1: Structural insights from stepwise shrinkage of a three-helix Fc-binding domain to a single helix. Protein Eng. Des. Sel., 30, 2017
3KGQ	Carboxypeptidase A liganded to an organic small-molecule: conformational changes 分子名称: ACETONE, CITRIC ACID, Carboxypeptidase A1, ... 著者 Fernandez, D, Boix, E, Pallares, I, Aviles, F.X, Vendrell, J. 登録日 2009-10-29 公開日 2010-10-27 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural and Functional Analysis of the Complex between Citrate and the Zinc Peptidase Carboxypeptidase A Enzyme Res, 2011, 2011
5U6G	Crystal Structure of the holo Domain-Swapped Dimer mutant Q108K:K40D Human Cellular Retinol Binding Protein II bound with all trans retinal 分子名称: RETINAL, Retinol-binding protein 2 著者 Assar, Z, Geiger, J.H. 登録日 2016-12-08 公開日 2017-10-18 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal Structure of the holo Domain-Swapped Dimer mutant Q108K:K40D Human Cellular Retinol Binding Protein II bound with all trans retinal To Be Published
5IXF	Solution structure of the STAM2 SH3 with AMSH derived peptide complex 分子名称: STAM-binding protein, Signal transducing adapter molecule 2 著者 Hologne, M, Cantrelle, F.X, Trivelli, X, Walker, O. 登録日 2016-03-23 公開日 2016-12-07 最終更新日 2024-06-19 実験手法 SOLUTION NMR 主引用文献 NMR Reveals the Interplay among the AMSH SH3 Binding Motif, STAM2, and Lys63-Linked Diubiquitin. J.Mol.Biol., 428, 2016
3KMR	Crystal structure of RARalpha ligand binding domain in complex with an agonist ligand (Am580) and a coactivator fragment 分子名称: 4-{[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbonyl]amino}benzoic acid, Nuclear receptor coactivator 1, Retinoic acid receptor alpha 著者 Bourguet, W, Teyssier, C. 登録日 2009-11-11 公開日 2010-06-02 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A unique secondary-structure switch controls constitutive gene repression by retinoic acid receptor. Nat.Struct.Mol.Biol., 17, 2010
3KFA	Structural analysis of DFG-in and DFG-out dual Src-Abl inhibitors sharing a common vinyl purine template 分子名称: 3-{(E)-2-[6-(cyclopropylamino)-9H-purin-9-yl]ethenyl}-4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]benzamide, Tyrosine-protein kinase ABL1 著者 Zhou, T. 登録日 2009-10-27 公開日 2009-12-22 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.22 Å) 主引用文献 Structural analysis of DFG-in and DFG-out dual Src-Abl inhibitors sharing a common vinyl purine template. Chem.Biol.Drug Des., 75, 2010
5JQS	Crystal structure of deubiquitinase MINDY-1 in complex with Ubiquitin 分子名称: 1,4-DIETHYLENE DIOXIDE, CHLORIDE ION, Protein FAM63A, ... 著者 Abdul Rehman, S.A, Kulathu, Y. 登録日 2016-05-05 公開日 2016-06-22 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 MINDY-1 Is a Member of an Evolutionarily Conserved and Structurally Distinct New Family of Deubiquitinating Enzymes. Mol.Cell, 63, 2016
3KYT	Crystal structure of orphan nuclear receptor RORgamma in complex with natural ligand 分子名称: 20-HYDROXYCHOLESTEROL, Nuclear receptor ROR-gamma, Nuclear receptor coactivator 2 著者 Martynowski, D, Li, Y. 登録日 2009-12-07 公開日 2010-03-16 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Structural basis for hydroxycholesterols as natural ligands of orphan nuclear receptor RORgamma. Mol.Endocrinol., 24, 2010
3KZF	Structure of Giardia Carbamate Kinase 分子名称: Carbamate kinase, GLYCEROL 著者 Galkin, A, Herzberg, O. 登録日 2009-12-08 公開日 2010-04-07 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 X-ray structure and characterization of carbamate kinase from the human parasite Giardia lamblia. Acta Crystallogr.,Sect.F, 66, 2010
5JS6	Crystal structure of 17beta-hydroxysteroid dehydrogenase 14 T205 variant in complex with NAD. 分子名称: 17-beta-hydroxysteroid dehydrogenase 14, CHLORIDE ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... 著者 Bertoletti, N, Marchais-Oberwinkler, S, Heine, A, Klebe, G. 登録日 2016-05-07 公開日 2016-07-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.002 Å) 主引用文献 New Insights into Human 17 beta-Hydroxysteroid Dehydrogenase Type 14: First Crystal Structures in Complex with a Steroidal Ligand and with a Potent Nonsteroidal Inhibitor. J.Med.Chem., 59, 2016

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