6C23
 
 | | Cryo-EM structure of PRC2 bound to cofactors AEBP2 and JARID2 in the Compact Active State | | 分子名称: | Histone-binding protein RBBP4, Histone-lysine N-methyltransferase EZH2, JARID2-substrate, ... | | 著者 | Kasinath, V, Faini, M, Poepsel, S, Reif, D, Feng, A, Stjepanovic, G, Aebersold, R, Nogales, E. | | 登録日 | 2018-01-05 | | 公開日 | 2018-01-24 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Structures of human PRC2 with its cofactors AEBP2 and JARID2.
Science, 359, 2018
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8JH4
 | | RNA polymerase II elongation complex containing 60 bp upstream DNA loop, stalled at SHL(-1) of the nucleosome | | 分子名称: | DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Akatsu, M, Fujita, R, Ogasawara, M, Ehara, H, Kujirai, T, Takizawa, Y, Sekine, S, Kurumizaka, H. | | 登録日 | 2023-05-22 | | 公開日 | 2023-11-29 | | 最終更新日 | 2023-12-20 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Cryo-EM structures of RNA polymerase II-nucleosome complexes rewrapping transcribed DNA.
J.Biol.Chem., 299, 2023
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7DDX
 | | Crystal structure of KANK1 S1179F mutant in complex wtih eIF4A1 | | 分子名称: | Eukaryotic initiation factor 4A-I, GLYCEROL, KN motif and ankyrin repeat domains 1, ... | | 著者 | Pan, W, Xu, Y, Wei, Z. | | 登録日 | 2020-10-30 | | 公開日 | 2021-09-08 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Nephrotic-syndrome-associated mutation of KANK2 induces pathologic binding competition with physiological interactor KIF21A.
J.Biol.Chem., 297, 2021
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8I0V
 | | The cryo-EM structure of human post-Bact complex | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, Crooked neck-like protein 1, ... | | 著者 | Zhan, X, Lu, Y, Shi, Y. | | 登録日 | 2023-01-11 | | 公開日 | 2024-07-31 | | 最終更新日 | 2024-08-07 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Molecular basis for the activation of human spliceosome.
Nat Commun, 15, 2024
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6HKT
 | | Structure of an H1-bound 6-nucleosome array | | 分子名称: | DNA (1122-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | | 著者 | Garcia-Saez, I, Dimitrov, S, Petosa, C. | | 登録日 | 2018-09-08 | | 公開日 | 2018-10-31 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (9.7 Å) | | 主引用文献 | Structure of an H1-Bound 6-Nucleosome Array Reveals an Untwisted Two-Start Chromatin Fiber Conformation.
Mol. Cell, 72, 2018
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7R1D
 | | Structure of MuvB complex | | 分子名称: | Histone-binding protein RBBP4, Protein lin-37 homolog, Protein lin-9 homolog | | 著者 | Koliopoulos, M.G, Alfieri, C. | | 登録日 | 2022-02-02 | | 公開日 | 2022-08-10 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structure of a nucleosome-bound MuvB transcription factor complex reveals DNA remodelling.
Nat Commun, 13, 2022
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2HXY
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7QWS
 | | Structure of ribosome translating beta-tubulin in complex with TTC5 and NAC | | 分子名称: | 28S rRNA, 5.8S rRNA, 5S rRNA, ... | | 著者 | Jomaa, A, Gamerdinger, M, Hsieh, H, Wallisch, A, Chandrasekaran, V, Ulusoy, Z, Scaiola, A, Hegde, R, Shan, S, Ban, N, Deuerling, E. | | 登録日 | 2022-01-25 | | 公開日 | 2022-03-09 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Mechanism of signal sequence handover from NAC to SRP on ribosomes during ER-protein targeting.
Science, 375, 2022
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3UVX
 | | Crystal Structure of the first bromodomain of human BRD4 in complex with a diacetylated histone 4 peptide (H4K12acK16ac) | | 分子名称: | 1,2-ETHANEDIOL, Bromodomain-containing protein 4, FORMIC ACID, ... | | 著者 | Filippakopoulos, P, Picaud, S, Keates, T, Ugochukwu, E, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2011-11-30 | | 公開日 | 2012-01-25 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | | 主引用文献 | Histone recognition and large-scale structural analysis of the human bromodomain family.
Cell(Cambridge,Mass.), 149, 2012
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7PEX
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7PEZ
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7PF3
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7PET
 | | The 4x177 nucleosome array containing H1 | | 分子名称: | DNA (702-MER), Histone H1.4, Histone H2A type 1-B/E, ... | | 著者 | Dombrowski, M, Cramer, P. | | 登録日 | 2021-08-11 | | 公開日 | 2022-08-03 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (9.5 Å) | | 主引用文献 | Histone H1 binding to nucleosome arrays depends on linker DNA length and trajectory.
Nat.Struct.Mol.Biol., 29, 2022
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7PF5
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7PF4
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7PFU
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7PF6
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7PEV
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7PF2
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7PFA
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7PFF
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7PEU
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7PFD
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7PFT
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7PFE
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