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3F62
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Crystal Structure of Human IL-18 in complex with Ectromelia virus IL-18 Binding Protein
分子名称: Interleukin 18 binding protein, Interleukin-18
著者Krumm, B.E, Li, Y, Deng, J.
登録日2008-11-05
公開日2009-01-06
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for antagonism of human interleukin 18 by poxvirus interleukin 18-binding protein.
Proc.Natl.Acad.Sci.USA, 105, 2008
7T78
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BU of 7t78 by Molmil
CRYSTAL STRUCTURE OF GLUCOKINASE (HEXOKINASE 4) COMPLEXED WITH LIGAND DIETHYL ({2-[3-(4-METHANESULFONYLPHENO XY)-5-{[(2S)-1-METHOXYPROPAN-2-YL]OXY}BENZAMIDO]-1,3-THIAZ OL-4-YL}METHYL)PHOSPHONATE
分子名称: 1,2-ETHANEDIOL, Isoform 2 of Hexokinase-4, SODIUM ION, ...
著者Muckelbauer, J.K.
登録日2021-12-14
公開日2022-03-02
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Discovery of a Partial Glucokinase Activator Clinical Candidate: Diethyl ((3-(3-((5-(Azetidine-1-carbonyl)pyrazin-2-yl)oxy)-5-isopropoxybenzamido)-1 H -pyrazol-1-yl)methyl)phosphonate (BMS-820132).
J.Med.Chem., 65, 2022
4QS9
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Arabidopsis Hexokinase 1 (AtHXK1) mutant S177A structure in glucose-bound form
分子名称: Hexokinase-1, beta-D-glucopyranose
著者Feng, J, Zhao, S, Liu, L.
登録日2014-07-03
公開日2015-02-11
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.103 Å)
主引用文献Biochemical and structural study of Arabidopsis hexokinase 1
Acta Crystallogr.,Sect.D, 71, 2015
4QS8
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Arabidopsis Hexokinase 1 (AtHXK1) structure in ligand-free form
分子名称: Hexokinase-1
著者Feng, J, Zhao, S, Liu, L.
登録日2014-07-03
公開日2015-02-11
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.798 Å)
主引用文献Biochemical and structural study of Arabidopsis hexokinase 1
Acta Crystallogr.,Sect.D, 71, 2015
4RCH
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BU of 4rch by Molmil
Discovery of 2-Pyridyl Ureas as Glucokinase Activators
分子名称: 1-{3-[(2-ethylpyridin-3-yl)oxy]-5-(pyridin-2-ylsulfanyl)pyridin-2-yl}-3-methylurea, Glucokinase, alpha-D-glucopyranose
著者Voegtli, W, Vigers, G.P.A.
登録日2014-09-16
公開日2014-10-08
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Discovery of 2-pyridylureas as glucokinase activators.
J.Med.Chem., 57, 2014
8J6K
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BU of 8j6k by Molmil
Crystal structure of pro-interleukin-18 and caspase-4 complex
分子名称: Arginine ADP-riboxanase OspC3, Caspase-4 subunit p10, Caspase-4 subunit p20, ...
著者Sun, Q, Hou, Y.J, Ding, J.
登録日2023-04-26
公開日2023-11-29
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.12 Å)
主引用文献Recognition and maturation of IL-18 by caspase-4 noncanonical inflammasome.
Nature, 624, 2023
5K93
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BU of 5k93 by Molmil
PapD wild-type chaperone
分子名称: Chaperone protein PapD
著者Sarowar, S, Li, H.
登録日2016-05-31
公開日2016-07-20
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The Escherichia coli P and Type 1 Pilus Assembly Chaperones PapD and FimC Are Monomeric in Solution.
J.Bacteriol., 198, 2016
6Z3T
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BU of 6z3t by Molmil
Structure of canine Sec61 inhibited by mycolactone
分子名称: Protein transport protein Sec61 subunit alpha isoform 1, Protein transport protein Sec61 subunit beta, Protein transport protein Sec61 subunit gamma, ...
著者Gerard, S.F, Higgins, M.K.
登録日2020-05-21
公開日2020-07-22
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (2.69 Å)
主引用文献Structure of the Inhibited State of the Sec Translocon.
Mol.Cell, 79, 2020
8SPB
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Caspase-4/Pro-IL-18 complex
分子名称: Caspase-4 subunit p10, Caspase-4 subunit p20, Interleukin-18
著者Pascal, D, Dong, Y, Wu, H, Jon, K.
登録日2023-05-02
公開日2023-11-22
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural insights into cytokine cleavage by inflammatory caspase-4.
Nature, 624, 2023
8SV1
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BU of 8sv1 by Molmil
Caspase-1 complex with interleukin-18
分子名称: Caspase-1, Interleukin-18
著者Dong, Y, Pascal, D, Jon, K, Wu, H.
登録日2023-05-15
公開日2024-05-08
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Caspase-1 complex with interleukin-18
To Be Published
6R7L
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BU of 6r7l by Molmil
Ribosome-bound SecYEG translocon in a nanodisc
分子名称: Protein translocase subunit SecY, SecE,Protein translocase subunit SecE,Protein translocase subunit SecE,Protein translocase subunit SecE, SecG
著者Kater, L, Beckmann, R, Kedrov, A.
登録日2019-03-29
公開日2019-08-07
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (6 Å)
主引用文献Partially inserted nascent chain unzips the lateral gate of the Sec translocon.
Embo Rep., 20, 2019
6R2N
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BU of 6r2n by Molmil
Crystal structure of KlGlk1 glucokinase from Kluyveromyces lactis
分子名称: 1,2-ETHANEDIOL, BROMIDE ION, Glucokinase-1
著者Zak, K, Wator, E, Grudnik, P.
登録日2019-03-18
公開日2019-10-16
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.596 Å)
主引用文献Crystal Structure of Kluyveromyces lactis Glucokinase ( Kl Glk1).
Int J Mol Sci, 20, 2019
1ZE3
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BU of 1ze3 by Molmil
Crystal Structure of the Ternary Complex of FIMD (N-Terminal Domain) with FIMC and the Pilin Domain of FIMH
分子名称: 1,2-ETHANEDIOL, Chaperone protein fimC, FimH protein, ...
著者Nishiyama, M, Horst, R, Eidam, O, Herrmann, T, Ignatov, O, Vetsch, M, Bettendorff, P, Jelesarov, I, Grutter, M.G, Wuthrich, K, Glockshuber, R, Capitani, G.
登録日2005-04-17
公開日2005-06-14
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Structural basis of chaperone-subunit complex recognition by the type 1 pilus assembly platform FimD.
Embo J., 24, 2005
1Z9S
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BU of 1z9s by Molmil
Crystal Structure of the native chaperone:subunit:subunit Caf1M:Caf1:Caf1 complex
分子名称: Chaperone protein Caf1M, F1 capsule antigen
著者Zavialov, A.V, Tischenko, V.M, Fooks, L.J, Brandsdal, B.O, Aqvist, J, Zav'yalov, V.P, Macintyre, S, Knight, S.D.
登録日2005-04-04
公開日2005-06-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Resolving the energy paradox of chaperone/usher-mediated fibre assembly
Biochem.J., 389, 2005
6VYG
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BU of 6vyg by Molmil
Cryo-EM structure of Plasmodium vivax hexokinase (Closed state)
分子名称: Phosphotransferase
著者Srivastava, S.S, Darling, J.E, Suryadi, J, Morris, J.C, Drew, M.E, Subramaniam, S.
登録日2020-02-26
公開日2020-05-06
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Plasmodium vivax and human hexokinases share similar active sites but display distinct quaternary architectures
Iucrj, 7, 2020
7WIJ
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BU of 7wij by Molmil
Cryo-EM structure of prenyltransferase domain of Macrophoma phaseolina macrophomene synthase
分子名称: Geranylgeranyl diphosphate synthase
著者Mori, T, Adachi, N, Abe, I.
登録日2022-01-03
公開日2022-06-22
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.17 Å)
主引用文献Discovery of non-squalene triterpenes.
Nature, 606, 2022
7XHA
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BU of 7xha by Molmil
Structure of the SecA/SecYE/proOmpA(4Y)-sfGFP complex with ADP.BeF3-.
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ...
著者Dong, L, Li, L.
登録日2022-04-07
公開日2023-01-11
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.35 Å)
主引用文献Structural basis of SecA-mediated protein translocation.
Proc.Natl.Acad.Sci.USA, 120, 2023
7XHB
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BU of 7xhb by Molmil
Structure of the SecA/SecYE/proOmpA(4Y)-sfGFP complex with ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Protein translocase subunit SecA, ...
著者Dong, L, Li, L.
登録日2022-04-07
公開日2023-01-11
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.33 Å)
主引用文献Structural basis of SecA-mediated protein translocation.
Proc.Natl.Acad.Sci.USA, 120, 2023
3JC2
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BU of 3jc2 by Molmil
The structure of the mammalian Sec61 channel opened by a signal sequence
分子名称: Prolactin, Protein transport protein Sec61 subunit alpha isoform 1, Protein transport protein Sec61 subunit beta, ...
著者Voorhees, R.M, Hegde, R.S.
登録日2015-11-15
公開日2016-01-13
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structure of the Sec61 channel opened by a signal sequence.
Science, 351, 2016
3JWN
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BU of 3jwn by Molmil
Complex of FimC, FimF, FimG and FimH
分子名称: Chaperone protein fimC, FimH protein, GLYCEROL, ...
著者Le Trong, I, Aprikian, P, Stenkamp, R.E, Sokurenko, E.V.
登録日2009-09-18
公開日2010-06-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Structural basis for mechanical force regulation of the adhesin FimH via finger trap-like beta sheet twisting.
Cell(Cambridge,Mass.), 141, 2010
3MP7
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Lateral opening of a translocon upon entry of protein suggests the mechanism of insertion into membranes
分子名称: Preprotein translocase subunit secE, Preprotein translocase subunit secY
著者Egea, P.F, Stroud, R.M, Center for Structures of Membrane Proteins (CSMP)
登録日2010-04-26
公開日2010-10-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Lateral opening of a translocon upon entry of protein suggests the mechanism of insertion into membranes.
Proc.Natl.Acad.Sci.USA, 107, 2010
3ME0
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BU of 3me0 by Molmil
Structure of the E. coli chaperone PAPD in complex with the pilin domain of the PapGII adhesin
分子名称: Chaperone protein papD, PapG protein
著者Ford, B.A, Elam, J.S, Dodson, K.W, Pinkner, J.S, Hultgren, S.J.
登録日2010-03-31
公開日2011-04-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Structure of the E. Coli Chaperone PapD in Complex with the Pilin Domain of the PapGII Adhesin
To be Published
3MJK
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Structure of a growth factor precursor
分子名称: Platelet-derived growth factor subunit A
著者Liu, H, He, X.
登録日2010-04-12
公開日2010-06-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structures of a platelet-derived growth factor/propeptide complex and a platelet-derived growth factor/receptor complex.
Proc.Natl.Acad.Sci.USA, 107, 2010
3O1W
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BU of 3o1w by Molmil
Crystal structure of dimeric KlHxk1 in crystal form III
分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, GLYCEROL, Hexokinase, ...
著者Kuettner, E.B, Kettner, K, Keim, A, Kriegel, T.M, Strater, N.
登録日2010-07-22
公開日2010-10-13
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Crystal Structure of Hexokinase KlHxk1 of Kluyveromyces lactis: A MOLECULAR BASIS FOR UNDERSTANDING THE CONTROL OF YEAST HEXOKINASE FUNCTIONS VIA COVALENT MODIFICATION AND OLIGOMERIZATION.
J.Biol.Chem., 285, 2010
7ZZI
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Plasmodium falciparum hexokinase complexed with glucose and citrate
分子名称: 1,2-ETHANEDIOL, CITRIC ACID, Phosphotransferase, ...
著者Fritz-Wolf, K, Dillenberger, M, Rahlfs, S, Becker, K.
登録日2022-05-25
公開日2023-08-30
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Analysis of Plasmodium falciparum Hexokinase Provides Novel Information about Catalysis Due to a Plasmodium -Specific Insertion.
Int J Mol Sci, 24, 2023

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